Center for Women's Reproductive Health (University-Wide Interdisciplinary Research Center)

Director:  Dwight Rouse, MD, MSPH

Established:  1993

 

Mission and Demographics

Established in 1993, the mission of the Center for Women’s Reproductive Health (CWRH) is to conduct research aimed at improving the reproductive health of all women, especially minority and under-served women and their families and to facilitate collaboration between UAB researchers and developing scholars interested in women's reproductive health issues.  The Center currently has 75 appointed faculty representing 16 departments and 6 schools at UAB.

Center Research  

The Center’s clinical research focus includes the following: improvement of infant mortality and pregnancy outcomes (particularly in disadvantaged and minority populations as well as in developing countries such as sub-Saharan Africa); prevention of premature labor; infectious disease in pregnancy and its relationship to premature labor; study of treatment strategies and their cost effectiveness in gynecological disorders such as infertility, dysfunctional uterine bleeding, pelvic inflammatory disease, menopause, pelvic relaxation/incontinence, and abnormal pap smears; study of treatment strategies aimed at cancerous gynecological disorders; development of novel therapeutics in reproductive tract cancers; prevention of maternal to fetal HIV transmission; evaluation of smoking cessation interventions; longitudinal studies aimed at nutrition status and intrauterine growth retardation and its relationship to child development; and cancer prevention and control. 

The Centre for Infectious Disease Research in Zambia (CIDRZ) continues its mission as an infectious disease and maternal-child health research unit, and to support and assist the Zambian government in its fight against AIDS.  Since its establishment in 1999, significant progress has been made in the development of service and research programs to fight AIDS.  Other significant health programs have since been added, including research and service programs for cervical cancer and TB.  A non-profit organization has been created to raise money to further develop a campus where faculty and staff will have the appropriate infrastructure for grants management, financial accounting, and training programs.  Because of funding from the President’s Emergency Plan for AIDS Relief (PEPFAR), CIDRZ currently supports HIV care and treatment at 50 clinical care sites in 22 districts and 4 provinces.  

The CWRH is also involved in basic/translational research, including extensive research activities in collaboration with the Division of Gene Therapy.  These activities include the development of novel strategies to accomplish gene therapy for ovarian cancer and rapid implementation of these strategies into clinical protocols.  Additional basic research activities include a productive collaborative relationship with the Microbiology Department in the area of mucosal immunology.  

Training

This Center has a number of training opportunities including K24 Mid-career Investigator Awards in the areas of Ovarian Cancer, Pelvic Floor disorders and Patient Oriented Obstetric Research.  It also has a K23 Young Investigator Award in the area of Perinatal HIV Prevention and several junior faculty have K01s.  In addition, the Center manages a K12 institutional training grant, the Women’s Reproductive Health Award, which trains Obstetrician/ Gynecologists in research careers.  Its intent is to train 4 to 6 Women’s Health Researchers from a number of different disciplines in a five year period.  The Center offers a competitive pilot/feasibility grant program each year for junior faculty.

The Center is also involved in a number of service programs.  The Colposcopy Clinic provides follow-up of abnormal pap smears for women referred by Jefferson and surrounding counties’ public health departments, as well as consultation/medical directorship of their patient screening protocols.  Center faculty are also involved in a service center, the Center for Genitourinary Disorders, that includes urogynecologists, urologists, geriatricians, health behaviorists, nurses and immunologists.  Finally, the Grace Clinic offers screening, evaluation and treatment for depression in pregnant and post partum women.

 

 

Approved by:  Dwight Rouse MD, Director

Date:  April 14, 2008

 

 

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