Small Animal Phenotyping
Core
Director: Tim R. Nagy, PhD
Department/Center
Association: Nutrition Sciences/Clinical
Established: 1996
The Small Animal Phenotyping Core provides investigators in the areas of
diabetes, obesity, and bone research with analysis of body composition (fat,
lean, and bone) and energy budgets in mice, rats, and other small animals.
Facility Description
Located in Volker Hall, the Core is fully equipped to
conduct body composition/energy expenditure/energy intake in small
rodents. Core equipment includes three
dual-energy X-ray absorptiometers, an in vivo
micro-CT scanner (30 to 100 micron resolution), an ex vivo micro-CT scanner (6-72 micron resolution), Faxitron MX-20, indirect and bomb calorimetry,
and glucose homeostasis studies. Our
latest additions to the Core are quantitative magnetic resonance machines that
allow us to determine fat and lean content in organisms and biopsies ranging
from 5mg to 100g (from fruit flies to 100 gram mice), and between 100g and 900g
(rats).
Research Information
The Core offers terminal and in vivo body composition analysis for investigators studying
changes in fat mass, lean mass, or bone density. In addition, the Core is also fully equipped
to measure the energy budgets of small rodents (food intake, energy
expenditure, core body temperature, and activity).
Contact Information
Director: Tim R. Nagy, PhD
Email: tnagy@uab.edu
Phone: 205-934-4088
Approved
by: Tim R. Nagy, PhD, Director
Date: March 7, 2008
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