Welcome

The goal of the UAB Vector Production Facility (VPF) is to accelerate the translation of novel viral vector-based therapies into Phase I trials in patients. Through the production of research and clinical grade vectors using Good Laboratory and current Good Manufacturing Practices, we assist investigators who wish to conduct safety and toxicity studies, submit investigational new drug (IND) applications and perform early stage clinical trials. The primary focus of the UAB VPF is the production of herpes simplex virus vectors and conditionally replicative adenoviral vectors, two promising platforms for cancer therapy.