In the News

  • Oct. 23, 2020: Bioinformatics Powertalk Seminar with Dr. Shahid Mukhtar

    Oct. 23, 2020: Bioinformatics Powertalk Seminar with Dr. Shahid Mukhtar Friday, Oct. 23 | 10 to 11 a.m. | Zoom MeetingPlease join us for the Informatics Institute PowerTalk Seminar Series-Bioinformatics!"Getting to the Edge of Biological Networks"Shahid M. Mukhtar, Ph.D.Associate ProfessorDepartments of Biology and SurgeryScientistNutrition Obesity Research CenterUAB School of MedicineAbstract: Networks consist of systems’ components, referred to as nodes and interactions between them, termed ‘edges’. Network representation of a typical biological system constitutes the direct and indirect interactions among diverse molecular components. Network analysis has been a recent focus in biological sciences due to its ability to synthesize global visualizations of cellular processes and predict functions based on inferences from network properties. The work in my laboratory focuses on the interface of experimental biology and network science to decode the molecular relationships among various systems’ components. In this presentation, I’ll focus on understanding the effects of chemical warfare agent exposure on the skin at cellular and system levels using murine and porcine biological models. Arsenicals are highly toxic and reactive inorganic and organic derivatives of arsenic, which can be harmful to human health. We used a systems biology “top-down” approach to identify key regulators and downstream genes involved in arsenical toxicity, focusing on the data-driven study of molecular mechanisms, signaling pathways,[…]

  • Oct. 16, 2020: PowerTalk Seminar Series: Clinical Informatics with Dr. Stu Booth

    Oct. 16, 2020: PowerTalk Seminar Series: Clinical Informatics with Dr. Stu Booth Friday, Oct. 16 | 10 to 11 a.m. | Zoom MeetingPlease join us for the Informatics Institute PowerTalk Seminar Series-Clinical Informatics!"CDS in the Fast Lane: Lessons Learned in the Emergency Department"James "Stu" Booth, M.D., MSHIMedical & Quality OfficerAssistant ProfessorDepartment of Emergency MedicineUAB School of MedicineAbstract: This talk will explore the intersection of clinical decision support and the fast-paced hectic environment of the emergency department. It will include examples from personal experience implementing alerts and other forms of CDS in the UAB emergency departments over the last 8 years. The talk will cover basic strategies of incorporating design principles, process improvement methods, and emergency department-specific workflow.Register for Zoom MeetingClick here to register for the seminar. Once you have registered you will receive a confirmation email containing information on how to access the webinar. 

  • Oct. 9, 2020: Bioinformatics Powertalk Seminar with Dr. Zechen Chong

    Oct. 9, 2020: Bioinformatics Powertalk Seminar with Dr. Zechen Chong Friday, Oct. 9 | 10 to 11 a.m. | Zoom MeetingPlease join us for the Informatics Institute PowerTalk Seminar Series-Bioinformatics!"Genomic Tools for Third-Generation Sequencing Data Analysis"Zechen Chong, Ph.D.Assistant Professor of Genetics and ScientistInformatics InstituteUAB School of MedicineAbstract: Genomic structural variation detection and genome assembly have been key challenges throughout the genomics era. Third-generation sequencing (TGS) technologies, such as PacBio SMRT and Oxford Nanopore, generate real-time sequencing of long single-molecular reads. Thus, they have great potential in accurately detecting genomic rearrangements and performing de novo assembly of genomes. However, there are few available tools, and their performance has been far from optimal. Our research focuses on developing algorithms and applications using TGS data. We have designed a suite of novel software packages that efficiently and accurately detect structural variations (DeBreak) and gene fusions (Fulloy), assemble bacteria genomes (B-assembler), and evaluate assembly results (Inspector). Based on both simulation data and real sequencing data, these tools have demonstrated improved performance when compared with currently available solutions. Our enhancements will benefit the biomedical research community by advancing the discovery of disease-causing and associated variations and our overall understanding of genomic architecture.Register for Zoom MeetingClick here to register for the seminar. Once you have registered you will receive[…]

  • Sept. 25, 2020: Bioinformatics Powertalk Seminar with Dr. Ryan Melvin

    Sept. 25, 2020: Bioinformatics Powertalk Seminar with Dr. Ryan Melvin Friday, Sept. 25 | 10 to 11 a.m. | Zoom MeetingPlease join us for the Informatics Institute PowerTalk Seminar Series-Bioinformatics!"Community-Relative Distance with Applications to Bioinformatics"Ryan Melvin, Ph.D.Assistant Professor of SurgeryDepartment of AnesthesiologyUAB School of MedicineRegister for Zoom MeetingClick here to register for the seminar. Once you have registered you will receive a confirmation email containing information on how to access the webinar. 

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