Hugh Kaul Precision Medicine Institute

Leading the way in precision medicine

Our aim is to enhance the delivery of precision medicine by assembling and supporting UAB researchers and clinicians in an interdisciplinary program aimed at discovering and applying new knowledge.

Precision medicine is a concept reshaping the way we think about human health, diagnosis and treatment of disease. It focuses on individual patients to understand how their lifestyles, behavior, environment and genetics interact to affect their health. More importantly, this allows a systematic approach to integrate these factors into the prevention, diagnosis and treatment of disease tailored to the individual patient.

At UAB, we integrate efforts related to discovery with implementation studies to advance new approaches to precision medicine to the clinic as rapidly as possible. Our multidisciplinary efforts in each of these domains capitalize on the strengths of the UAB Health System, School of Medicine, University of Alabama Health Services Foundation and our strategic partners, HudsonAlpha Institute for Biotechnology and Southern Research.

The Hugh Kaul Foundation generously gave $7 million to establish the UAB Hugh Kaul Precision Medicine Institute in order to pave the way for significant growth and acceleration of precision medicine in Alabama, the region and beyond.

Focus Areas

Advancing health care using prevention, diagnosis and treatment

Rare Diseases

Rare Diseases

Ending the diagnostic odyssey and developing precisely targeted treatments based on a patient’s unique genetic makeup



Combining patient-specific clinical, demographic and genomic information to personalize medication choice to improve effectiveness of drug therapy, with current programs in multiple areas, including mental health and cardiovascular disease



Providing the most accurate and cutting-edge treatments to each individual cancer patient based on the genetic profile of the tumor

Are you a patient or provider wanting to learn more about precision medicine at UAB? Visit UAB Medicine.


Leveraging knowledge from the brightest minds in the field

  • Informatics Institute

    Integrating genomic information into the electronic health record

  • O'Neal Comprehensive Cancer Center at UAB

    Developing new approaches to early diagnosis, prevention and treatment of cancer

  • Undiagnosed Diseases Program

    Combining a multidisciplinary team with the power of genomic sequencing to end the diagnostic odyssey

  • Alabama Genomic Health Initiative (AGHI)

    Harnessing the power of genomics to enhance health of citizens in the state

  • All of Us Research Program

    Engaging diverse communities in our region to participate in a historic national study that will enhance precision medicine for decades to come

  • HudsonAlpha Institute for Biotechnology

    Bringing state-of-the-art genomic technology and expertise to solve medical puzzles in rare and common diseases

  • Southern Research

    Discovering new drugs to develop targeted treatments

    Our team

    Meet our experts


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