• Purpose:

    To engage a collaborative working group to coordinate, collate, and facilitate the rigorous and expeditious completion of COVID-19 health services, outcomes and population health studies conducted by interdisciplinary research teams addressing prescient questions germane to the individuals, communities and populations we serve in our city, county, state, and Deep South region. 

     

    Functions:

    • Collation / Clearinghouse of COVID-19 databases (e.g., health system registries, ADPH surveillance)
    • Determination and development of specific COVID-19 cohorts / phenotypes (e.g., testing, ICU)
    • Concept Proposal coordination: submission, review, feedback (web based, REDCap platform)
    • Identify interdisciplinary investigators to form research teams for ‘approved’ Concept Proposals
    • Database / Informatics liaison to generate study specific datasets
    • BERD liaison to provide feedback and support for design, data analysis, interpretation and dissemination
    • Explore multisite collaborative opportunities for Concept Proposals across the CCTS Partner Network
    • Leadership

      Emily Levitan, ScD

      Emily Levitan, ScD
      CORE Co-Chair
      Co-Director, Center for Outcomes and Effectiveness Research and Education
      Associate Professor, Epidemiology
      School of Public Health

      Michael Mugavero, MD, MHSc

      Michael Mugavero, MD, MHSc
      CORE Co-Chair
      Co-Director, Center for Outcomes and Effectiveness Research and Education
      Director, CCTS Training Academy
      Professor, Infectious Diseases
      School of Medicine

      Becky Reamey, PhD

      Becky Reamey, PhD
      Program Director, Scientific Community of Outcomes Researchers
      Program Director, Center for Clinical and Translational Science (CCTS) Training Academy

       

    • Organizational Chart

      COVID CORE Flow 2 

    • Advisory Committee

      Andrew Butler, MPT, MBA, PhD

      Andrew Butler, MPT, MBA, PhD
      Dean, School of Health Professions

      James Cimino, MD

      James Cimino, MD
      Senior Scientist, Informatics Institute
      School of Medicine

      Paulette Dilworth, PhD

      Paulette Dilworth, PhD
      Vice President Diversity, Equity and Inclusion

      Craig Hoesley, MD

      Craig Hoesley, MD
      Professor, Infectious Diseases
      School of Medicine

      Tony Jones, MD

      Keith A. (Tony) Jones, MD
      Senior Associate Dean
      Clinical Affairs

      Robert Kimberly, MD

      Robert Kimberly, MD
      Director, Center for Clinical and Translational Science
      Professor of Medicine, Immunology and Immunotherapeutics
      School of Medicine

      Jeanne Marrazzo, MD

      Jeanne Marrazzo, MD
      Professor of Medicine, Infectious Disease
      School of Medicine

      Kristi Menear, PhD

      Kristi Menear, PhD
      Professor, Department of Human Studies
      School of Medicine

      Paul Muntner, PhD

      Paul Muntner, PhD
      Professor and Associate Dean, Epidemiology 
      School of Public Health

      Kenneth Saag, MD

      Kenneth Saag, MD
      Director, Center for Outcomes and Effectiveness Research and Education
      Professor of Medicine, Immunology
      School of Medicine

      David Schwebel, PhD

      David Schwebel, PhD
      University Professor
      Associate Dean for Research
      College of Arts and Sciences

      David Vance, Phd, MGS, MS

      David Vance, Phd, MGS, MS
      Professor and Associate Dean
      School of Nursing

      Molly Wasko, PhD

      Molly Wasko, PhD
      Professor and Associate Dean
      Collat School of Business

     

  • Programmatic Groups: Building the Research Platform

    Programmatic groups convene interdisciplinary faculty spanning schools at UAB to define and prioritize existing (for secondary analyses) and desired (for future capture) data elements for inclusion in a shared CORE research platform. These time-limited groups define the data elements initially available and then transition to a dormant phase, with reactivation, as needed, as new data elements come available for addition to the CORE research platform. Programmatic groups are closed and included invited individuals spanning diverse scientific disciplines and Schools at UAB.

    • Programmatic Working Group 1: Health System Data

      Co-Chairs:

      James Willig and Matt Wyatt

      Members:

      Sue Feldman, Craig Hoesley, Anand Iyer, Kierstin Kennedy, Yulia Khodneva, Rachael Lee, Audrey Lloyd, Patricia Patrician, David Redden

      Goals:

      • Define case definitions for cohorts (e.g. testing, PUI, confirmed cases)
      • Determine harmonized catalog of health systems data elements
        • Determine structured data elements amenable to query
        • Determine unstructured data elements requiring abstraction
      • Develop data management/data coordination procedures

       

    • Programmatic Working Group 2: Questionnaire & Patient Reported Outcome Data

      Co-Chairs:

      Allyson Hall and Faith Fletcher

      Members:

      Mirjam-Collette Kempf, Merry-Lynn McDonald, Gabrielle Rocque, Patricia Patrician, Libby Van Gerwen

      Goals:

      • Identify potenal questionnaires/validated instruments and Patient Reported Outcomes (PROs) for adjunctive data capture
      • Determine prioritization for questionnaire and PRO administration
      • Define timing, frequency and preferred modality of questionnaire and PRO administration

       

       

    • Programmatic Working Group 3: Community & Public Health Data

      Co-chairs:

      Irfan Asif and Monica Aswani

      Members:

      Ellen Eaton, Eric Ford, Brandi McCleskey, Becky Reamey

      Goals:

      • Identify and collate sources of COVID-19 community data capture
      • Liaise with Jefferson County Health Department and Alabama Department of Public Health re: COVID-19 surveillance data capture
      • Liaise with the City of Birmingham #BHMStrong team re: non-health related data capture germane to COVID-19 (e.g., economic, employment)
    • Programmatic Working Group 4: Research Coordinating Committee

      Co-chairs:

      Emily Levitan and Mike Mugavero

      Members:

       Jeff Foster, Lisa Jackson, Dustin Long, Aadia Rana

      Goals:

      • Determine human subjects and regulatory considerations with IRB
      • Develop COVID-19 CORE Concept Proposal
      • Develop procedures for project coordination following concept proposal submission in collaboration with data management/data coordination and BERD (Biostatistics, Epidemiology, Research Design)

  • Scientific Groups: Conducting Thematic Outcomes Research Studies

    Scientific groups convene interdisciplinary investigators with shared interests in thematic areas to vet ideas, hone research questions, build interdisciplinary study teams and facilitate concept proposal submissions. Scientific groups are open to all interested faculty, staff, and students at UAB.

    • Scientific Working Group 1: Health Disparities

      Co-Leaders:

      Faith Fletcher, Allyson Hall & Mandy Willig

      Join the Health Disparities Working Group:

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    • Scientific Working Group 2: Neurocognition

      Co-Chairs:

      Drs. Richard Kennedy & David Vance

      NeuroAdvisors:

      Shruti Agnihotri, Laura Dreer, Adam Gerstenecker, Ron Lazar, Kristine Lokken, Roy Martin, John Osborne, Pariya Wheeler 

      The UAB NeuroCOVID Group was formed in May 2020 in response to the emerging COVID-19 pandemic.  We are a group of clinicians and researchers across UAB (Department of Neurology, School of Nursing, Integrative Center for Aging Research, Informatic Institute, etc.) dedicated to understanding the impact of short-term and long-term COVID exposure on neuropsychological phenomenon ranging from cognition, “fogginess”, delirium, smell/taste, depression, and social isolation.  Our foci are transdisciplinary extending to various clinical populations (i.e., HIV, dementia, elderly).  We are developing protocols to collect neuroCOVID data from various UAB clinics and producing scholarly products (i.e., articles, presentations, grants).  We meet biweekly to share updates and opportunities for building community and infrastructure to generate cutting-edge scholarship in this area.

      For more information about our group and how to be involved, please contact Dr. David Vance (This email address is being protected from spambots. You need JavaScript enabled to view it.) for more information.

       Publications:

      Parallels Between Neuro HIV and Neuro COVID-19

    • Scientific Working Group 3: Critical Care

      Co-leaders:

      Sheetal Gandotra, Russell Griffin & Derek Russell

      Join the Critical Care Working Group:

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    • Scientific Working Group 4: Financial & Operational Implications

      Co-leaders:

      Eric Ford, Bunyamin (Ben) Ozaydin & Ferhat Zengul

      Join the Financial & Operational Implications Working Group:

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    • Scientific Working Group 5: Chronic Co-morbidities

      Co-leaders:

      Lyse Norian & Gabrielle Rocque

      Join the Chronic Co-morbidities Working Group:

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    • Scientific Working Group 6: Patient Safety & Quality

      Co-leaders:

      Patricia Patrician

      Join the Patient Safety & Quality Working Group:

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    • Scientific Working Group 7: Healthcare Worker Well-being & Satisfaction

      Co-leaders:

      Greer Burkholder, Crystal Chapman-Lambert, Katherine Meese

      Join the Healthcare Worker Well-being & Satisfaction Working Group:

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    Suggest a new scientific working group:

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    • Process & FAQs
      • Once a Concept Proposal has been submitted, a member of the CORE team will reach out to schedule a Scientific Gateway Meeting. This is a call with the investigative teamt that includes representatives from Enterprise Data Warehouse (EDW), Clinical/Medical Informatics, CCTS BERD (Biostats, Epi, Research Design) and COERE/outcomes research. The concept proposal will be distributed to this group in advance of the call to facilitate a more informed discussion.
      •  The Scientific Gateway Meeting ultimately leads to a Data Gateway Meeting which is requested by submitting a Data Extraction/Transformation request form.  Data Extraction/Transformation requests generate a study specific analysis dataset. Once submitted, a member of the CORE team will reach out to schedule a Data Gateway Meeting. This is a call with the investigative team that includes representatives from Enterprise Data Warehouse (EDW) and Clinical/Medical Informatics. The completed Data Extraction/Transformation request form will be distributed to this group in advance of the call to facilitate a more informed discussion.

      Concept Proposal Gateway Flow Chart

    • Request a Scientific Gateway Meeting

      Once submitted, a member of the CORE team will reach out to you to schedule a Scientific Gateway Meeting. This is a call with your investigative team that will include representatives from Enterprise Data Warehouse (EDW), Clinical/Medical Informatics, CCTS BERD (Biostats, Epi, Research Design) and COERE/outcomes research. Your concept proposal will be distributed to this group in advance of the call to facilitate a more informed discussion.

       

      Request a Scientific Gateway Meeting

    • Request a Data Gateway Meeting

      Request a Data Gateway meeting n to generate a study specific analysis-ready dataset. Once submitted, a member of the CORE team will reach out to you to schedule a Data Gateway Meeting. This is a call with your investigative team that will include representatives from Enterprise Data Warehouse (EDW) and Clinical/Medical Informatics. Your Data Extraction/Transformation Request will be distributed to this group in advance of the call to facilitate a more informed discussion.

       

      Request a Data Gateway Meeting 

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