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Purpose:
To engage a collaborative working group to coordinate, collate, and facilitate the rigorous and expeditious completion of COVID-19 health services, outcomes and population health studies conducted by interdisciplinary research teams addressing prescient questions germane to the individuals, communities and populations we serve in our city, county, state, and Deep South region.
Functions:
- Collation / Clearinghouse of COVID-19 databases (e.g., health system registries, ADPH surveillance)
- Determination and development of specific COVID-19 cohorts / phenotypes (e.g., testing, ICU)
- Concept Proposal coordination: submission, review, feedback (web based, REDCap platform)
- Identify interdisciplinary investigators to form research teams for ‘approved’ Concept Proposals
- Database / Informatics liaison to generate study specific datasets
- BERD liaison to provide feedback and support for design, data analysis, interpretation and dissemination
- Explore multisite collaborative opportunities for Concept Proposals across the CCTS Partner Network
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Leadership
Emily Levitan, ScD
CORE Co-Chair
Co-Director, Center for Outcomes and Effectiveness Research and Education
Associate Professor, Epidemiology
School of Public HealthMichael Mugavero, MD, MHSc
CORE Co-Chair
Co-Director, Center for Outcomes and Effectiveness Research and Education
Director, CCTS Training Academy
Professor, Infectious Diseases
School of MedicineBecky Reamey, PhD
Program Director, Scientific Community of Outcomes Researchers
Program Director, Center for Clinical and Translational Science (CCTS) Training AcademyOrganizational Chart
Advisory Committee
Andrew Butler, MPT, MBA, PhD
Dean, School of Health ProfessionsJames Cimino, MD
Senior Scientist, Informatics Institute
School of MedicinePaulette Dilworth, PhD
Vice President Diversity, Equity and InclusionCraig Hoesley, MD
Professor, Infectious Diseases
School of MedicineKeith A. (Tony) Jones, MD
Senior Associate Dean
Clinical AffairsRobert Kimberly, MD
Director, Center for Clinical and Translational Science
Professor of Medicine, Immunology and Immunotherapeutics
School of MedicineJeanne Marrazzo, MD
Professor of Medicine, Infectious Disease
School of MedicineKristi Menear, PhD
Professor, Department of Human Studies
School of MedicinePaul Muntner, PhD
Professor and Associate Dean, Epidemiology
School of Public HealthKenneth Saag, MD
Director, Center for Outcomes and Effectiveness Research and Education
Professor of Medicine, Immunology
School of MedicineDavid Schwebel, PhD
University Professor
Associate Dean for Research
College of Arts and SciencesDavid Vance, Phd, MGS, MS
Professor and Associate Dean
School of NursingMolly Wasko, PhD
Professor and Associate Dean
Collat School of Business -
Programmatic Groups: Building the Research Platform
Programmatic groups convene interdisciplinary faculty spanning schools at UAB to define and prioritize existing (for secondary analyses) and desired (for future capture) data elements for inclusion in a shared CORE research platform. These time-limited groups define the data elements initially available and then transition to a dormant phase, with reactivation, as needed, as new data elements come available for addition to the CORE research platform. Programmatic groups are closed and included invited individuals spanning diverse scientific disciplines and Schools at UAB.
Programmatic Working Group 1: Health System Data
Co-Chairs:
James Willig and Matt Wyatt
Members:
Sue Feldman, Craig Hoesley, Anand Iyer, Kierstin Kennedy, Yulia Khodneva, Rachael Lee, Audrey Lloyd, Patricia Patrician, David Redden
Goals:
- Define case definitions for cohorts (e.g. testing, PUI, confirmed cases)
- Determine harmonized catalog of health systems data elements
- Determine structured data elements amenable to query
- Determine unstructured data elements requiring abstraction
- Develop data management/data coordination procedures
Programmatic Working Group 2: Questionnaire & Patient Reported Outcome Data
Co-Chairs:
Allyson Hall and Faith Fletcher
Members:
Mirjam-Collette Kempf, Merry-Lynn McDonald, Gabrielle Rocque, Patricia Patrician, Libby Van Gerwen
Goals:
- Identify potenal questionnaires/validated instruments and Patient Reported Outcomes (PROs) for adjunctive data capture
- Determine prioritization for questionnaire and PRO administration
- Define timing, frequency and preferred modality of questionnaire and PRO administration
Programmatic Working Group 3: Community & Public Health Data
Co-chairs:
Irfan Asif and Monica Aswani
Members:
Ellen Eaton, Eric Ford, Brandi McCleskey, Becky Reamey
Goals:
- Identify and collate sources of COVID-19 community data capture
- Liaise with Jefferson County Health Department and Alabama Department of Public Health re: COVID-19 surveillance data capture
- Liaise with the City of Birmingham #BHMStrong team re: non-health related data capture germane to COVID-19 (e.g., economic, employment)
Programmatic Working Group 4: Research Coordinating Committee
Co-chairs:
Emily Levitan and Mike Mugavero
Members:
Jeff Foster, Lisa Jackson, Dustin Long, Aadia Rana
Goals:
- Determine human subjects and regulatory considerations with IRB
- Develop COVID-19 CORE Concept Proposal
- Develop procedures for project coordination following concept proposal submission in collaboration with data management/data coordination and BERD (Biostatistics, Epidemiology, Research Design)
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Scientific Groups: Conducting Thematic Outcomes Research Studies
Scientific groups convene interdisciplinary investigators with shared interests in thematic areas to vet ideas, hone research questions, build interdisciplinary study teams and facilitate concept proposal submissions. Scientific groups are open to all interested faculty, staff, and students at UAB.
Scientific Working Group 1: Health Disparities
Co-Leaders:
Faith Fletcher, Allyson Hall & Mandy Willig
Join the Health Disparities Working Group:
Scientific Working Group 2: Neurocognition
Co-Leaders:
Richard Kennedy & David Vance
Join the Neurocognition Working Group:
Scientific Working Group 3: Critical Care
Co-leaders:
Sheetal Gandotra, Russell Griffin & Derek Russell
Join the Critical Care Working Group:
Scientific Working Group 4: Financial & Operational Implications
Co-leaders:
Eric Ford, Bunyamin (Ben) Ozaydin & Ferhat Zengul
Join the Financial & Operational Implications Working Group:
Scientific Working Group 5: Chronic Co-morbidities
Co-leaders:
Lyse Norian & Gabrielle Rocque
Join the Chronic Co-morbidities Working Group:
Scientific Working Group 6: Patient Safety & Quality
Co-leaders:
Patricia Patrician
Join the Patient Safety & Quality Working Group:
Scientific Working Group 7: Healthcare Worker Well-being & Satisfaction
Co-leaders:
Greer Burkholder, Crystal Chapman-Lambert, Katherine Meese
Join the Healthcare Worker Well-being & Satisfaction Working Group:
Suggest a new scientific working group:
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Process & FAQs
- Once a Concept Proposal has been submitted, a member of the CORE team will reach out to schedule a Scientific Gateway Meeting. This is a call with the investigative teamt that includes representatives from Enterprise Data Warehouse (EDW), Clinical/Medical Informatics, CCTS BERD (Biostats, Epi, Research Design) and COERE/outcomes research. The concept proposal will be distributed to this group in advance of the call to facilitate a more informed discussion.
- The Scientific Gateway Meeting ultimately leads to a Data Gateway Meeting which is requested by submitting a Data Extraction/Transformation request form. Data Extraction/Transformation requests generate a study specific analysis dataset. Once submitted, a member of the CORE team will reach out to schedule a Data Gateway Meeting. This is a call with the investigative team that includes representatives from Enterprise Data Warehouse (EDW) and Clinical/Medical Informatics. The completed Data Extraction/Transformation request form will be distributed to this group in advance of the call to facilitate a more informed discussion.
Submit a Concept Proposal
Once submitted, a member of the CORE team will reach out to you to schedule a Scientific Gateway Meeting. This is call with your investigative team that will include representatives from Enterprise Data Warehouse (EDW), Clinical/Medical Informatics, CCTS BERD (Biostats, Epi, Research Design) and COERE/outcomes research. Your concept proposal will be distributed to this group in advance of the call to facilitate a more informed discussion.
Request Data Extraction/Transformation
Request Data Extraction/Transformation to generate a study specific analysis dataset. Once submitted, a member of the CORE team will reach out to you to schedule a Data Gateway Meeting. This is call with your investigative team that will include representatives from Enterprise Data Warehouse (EDW) and Clinical/Medical Informatics. Your Data Extraction/Transformation Request will be distributed to this group in advance of the call to facilitate a more informed discussion.
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