• Purpose:

    To engage a collaborative working group to coordinate, collate, and facilitate the rigorous and expeditious completion of COVID-19 health services, outcomes and population health studies conducted by interdisciplinary research teams addressing prescient questions germane to the individuals, communities and populations we serve in our city, county, state, and Deep South region. 

     

    Functions:

    • Collation / Clearinghouse of COVID-19 databases (e.g., health system registries, ADPH surveillance)
    • Determination and development of specific COVID-19 cohorts / phenotypes (e.g., testing, ICU)
    • Concept Proposal coordination: submission, review, feedback (web based, REDCap platform)
    • Identify interdisciplinary investigators to form research teams for ‘approved’ Concept Proposals
    • Database / Informatics liaison to generate study specific datasets
    • BERD liaison to provide feedback and support for design, data analysis, interpretation and dissemination
    • Explore multisite collaborative opportunities for Concept Proposals across the CCTS Partner Network
  • Leadership

    Emily Levitan, ScD

    Emily Levitan, ScD
    CORE Co-Chair
    Co-Director, Center for Outcomes and Effectiveness Research and Education
    Associate Professor, Epidemiology
    School of Public Health

    Michael Mugavero, MD, MHSc

    Michael Mugavero, MD, MHSc
    CORE Co-Chair
    Co-Director, Center for Outcomes and Effectiveness Research and Education
    Director, CCTS Training Academy
    Professor, Infectious Diseases
    School of Medicine

    Becky Reamey, PhD

    Becky Reamey, PhD
    Program Director, Scientific Community of Outcomes Researchers
    Program Director, Center for Clinical and Translational Science (CCTS) Training Academy

    Organizational Chart

    COVID CORE Flow 2 

    Advisory Committee

    Andrew Butler, MPT, MBA, PhD

    Andrew Butler, MPT, MBA, PhD
    Dean, School of Health Professions

    James Cimino, MD

    James Cimino, MD
    Senior Scientist, Informatics Institute
    School of Medicine

    Paulette Dilworth, PhD

    Paulette Dilworth, PhD
    Vice President Diversity, Equity and Inclusion

    Craig Hoesley, MD

    Craig Hoesley, MD
    Professor, Infectious Diseases
    School of Medicine

    Tony Jones, MD

    Keith A. (Tony) Jones, MD
    Senior Associate Dean
    Clinical Affairs

    Robert Kimberly, MD

    Robert Kimberly, MD
    Director, Center for Clinical and Translational Science
    Professor of Medicine, Immunology and Immunotherapeutics
    School of Medicine

    Jeanne Marrazzo, MD

    Jeanne Marrazzo, MD
    Professor of Medicine, Infectious Disease
    School of Medicine

    Kristi Menear, PhD

    Kristi Menear, PhD
    Professor, Department of Human Studies
    School of Medicine

    Paul Muntner, PhD

    Paul Muntner, PhD
    Professor and Associate Dean, Epidemiology 
    School of Public Health

    Kenneth Saag, MD

    Kenneth Saag, MD
    Director, Center for Outcomes and Effectiveness Research and Education
    Professor of Medicine, Immunology
    School of Medicine

    David Schwebel, PhD

    David Schwebel, PhD
    University Professor
    Associate Dean for Research
    College of Arts and Sciences

    David Vance, Phd, MGS, MS

    David Vance, Phd, MGS, MS
    Professor and Associate Dean
    School of Nursing

    Molly Wasko, PhD

    Molly Wasko, PhD
    Professor and Associate Dean
    Collat School of Business

     

  • Programmatic Groups: Building the Research Platform

    Programmatic groups convene interdisciplinary faculty spanning schools at UAB to define and prioritize existing (for secondary analyses) and desired (for future capture) data elements for inclusion in a shared CORE research platform. These time-limited groups define the data elements initially available and then transition to a dormant phase, with reactivation, as needed, as new data elements come available for addition to the CORE research platform. Programmatic groups are closed and included invited individuals spanning diverse scientific disciplines and Schools at UAB.

    Programmatic Working Group 1: Health System Data

    Co-Chairs:

    James Willig and Matt Wyatt

    Members:

    Sue Feldman, Craig Hoesley, Anand Iyer, Kierstin Kennedy, Yulia Khodneva, Rachael Lee, Audrey Lloyd, Patricia Patrician, David Redden

    Goals:

    • Define case definitions for cohorts (e.g. testing, PUI, confirmed cases)
    • Determine harmonized catalog of health systems data elements
      • Determine structured data elements amenable to query
      • Determine unstructured data elements requiring abstraction
    • Develop data management/data coordination procedures

     

    Programmatic Working Group 2: Questionnaire & Patient Reported Outcome Data

    Co-Chairs:

    Allyson Hall and Faith Fletcher

    Members:

    Mirjam-Collette Kempf, Merry-Lynn McDonald, Gabrielle Rocque, Patricia Patrician, Libby Van Gerwen

    Goals:

    • Identify potenal questionnaires/validated instruments and Patient Reported Outcomes (PROs) for adjunctive data capture
    • Determine prioritization for questionnaire and PRO administration
    • Define timing, frequency and preferred modality of questionnaire and PRO administration

     

     

    Programmatic Working Group 3: Community & Public Health Data

    Co-chairs:

    Irfan Asif and Monica Aswani

    Members:

    Ellen Eaton, Eric Ford, Brandi McCleskey, Becky Reamey

    Goals:

    • Identify and collate sources of COVID-19 community data capture
    • Liaise with Jefferson County Health Department and Alabama Department of Public Health re: COVID-19 surveillance data capture
    • Liaise with the City of Birmingham #BHMStrong team re: non-health related data capture germane to COVID-19 (e.g., economic, employment)

    Programmatic Working Group 4: Research Coordinating Committee

    Co-chairs:

    Emily Levitan and Mike Mugavero

    Members:

     Jeff Foster, Lisa Jackson, Dustin Long, Aadia Rana

    Goals:

    • Determine human subjects and regulatory considerations with IRB
    • Develop COVID-19 CORE Concept Proposal
    • Develop procedures for project coordination following concept proposal submission in collaboration with data management/data coordination and BERD (Biostatistics, Epidemiology, Research Design)

  • Scientific Groups: Conducting Thematic Outcomes Research Studies

    Scientific groups convene interdisciplinary investigators with shared interests in thematic areas to vet ideas, hone research questions, build interdisciplinary study teams and facilitate concept proposal submissions. Scientific groups are open to all interested faculty, staff, and students at UAB.

    Scientific Working Group 1: Health Disparities

    Co-Leaders:

    Faith Fletcher, Allyson Hall & Mandy Willig

    Join the Health Disparities Working Group:

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    Scientific Working Group 2: Neurocognition

    Co-Leaders:

    Richard Kennedy & David Vance

    Join the Neurocognition Working Group:

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    Scientific Working Group 3: Critical Care

    Co-leaders:

    Sheetal Gandotra, Russell Griffin & Derek Russell

    Join the Critical Care Working Group:

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    Scientific Working Group 4: Financial & Operational Implications

    Co-leaders:

    Eric Ford, Bunyamin (Ben) Ozaydin & Ferhat Zengul

    Join the Financial & Operational Implications Working Group:

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    Scientific Working Group 5: Chronic Co-morbidities

    Co-leaders:

    Lyse Norian & Gabrielle Rocque

    Join the Chronic Co-morbidities Working Group:

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    Scientific Working Group 6: Patient Safety & Quality

    Co-leaders:

    Patricia Patrician

    Join the Patient Safety & Quality Working Group:

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    Scientific Working Group 7: Healthcare Worker Well-being & Satisfaction

    Co-leaders:

    Greer Burkholder, Crystal Chapman-Lambert, Katherine Meese

    Join the Healthcare Worker Well-being & Satisfaction Working Group:

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    Suggest a new scientific working group:

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  • Process & FAQs

    • Once a Concept Proposal has been submitted, a member of the CORE team will reach out to schedule a Scientific Gateway Meeting. This is a call with the investigative teamt that includes representatives from Enterprise Data Warehouse (EDW), Clinical/Medical Informatics, CCTS BERD (Biostats, Epi, Research Design) and COERE/outcomes research. The concept proposal will be distributed to this group in advance of the call to facilitate a more informed discussion.
    •  The Scientific Gateway Meeting ultimately leads to a Data Gateway Meeting which is requested by submitting a Data Extraction/Transformation request form.  Data Extraction/Transformation requests generate a study specific analysis dataset. Once submitted, a member of the CORE team will reach out to schedule a Data Gateway Meeting. This is a call with the investigative team that includes representatives from Enterprise Data Warehouse (EDW) and Clinical/Medical Informatics. The completed Data Extraction/Transformation request form will be distributed to this group in advance of the call to facilitate a more informed discussion.

    Concept Proposal Gateway Flow Chart

    Submit a Concept Proposal

    Once submitted, a member of the CORE team will reach out to you to schedule a Scientific Gateway Meeting. This is call with your investigative team that will include representatives from Enterprise Data Warehouse (EDW), Clinical/Medical Informatics, CCTS BERD (Biostats, Epi, Research Design) and COERE/outcomes research. Your concept proposal will be distributed to this group in advance of the call to facilitate a more informed discussion.

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    Request Data Extraction/Transformation

    Request Data Extraction/Transformation to generate a study specific analysis dataset. Once submitted, a member of the CORE team will reach out to you to schedule a Data Gateway Meeting. This is call with your investigative team that will include representatives from Enterprise Data Warehouse (EDW) and Clinical/Medical Informatics. Your Data Extraction/Transformation Request will be distributed to this group in advance of the call to facilitate a more informed discussion.

    *Please note the following:

    1. Once we have completed the data request and mappings, depending on the complexity and existing work queue we will provide you with an estimated date of completion. Please keep in mind that our team serves multiple investigators and interests within the institution. 

    2. Expect to be contacted within 2 business days from form submission for clarification. 

    3. Once you receive data, please review carefully and ensure that it meets your needs. You will have 3 business days to contact us for clarifications/changes to request.  Requests for changes received after this time period will result in your query returning to the bottom of the New Request queue.

    **Data requests should NOT include protected health information (PHI) such as names, MRNs, birthdates, etc.

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    - Sheet 1: Variables that appear once in a dataset (demographics and patient related data as well as any variables you are calculating to be one indicator per person) - All subsequent Sheets: Patient identifier/FIN, Encounter or NA/Requested Variable Variables that appear more than once

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