Phone: (205) 996-5099
E-mail: qinwang@uab.edu

Research/Clinical Interest Description: The long term goal of our research is to reveal novel regulatory pathways controlling G protein-coupled receptors (GPCRs) functions at the molecular and cellular levels and to understand how these regulatory mechanisms influence GPCR-elicited physiological functions in vivo, so as to provide new insights for therapeutic strategies. Current projects include: 1) regulation of alpha2A adrenergic receptor trafficking and signaling in native neurons exploiting gene knock-in and knock-out mice; 2) regulation of adenosine-mediated synaptic plasticity and behavior; 3) functions of the alpha2A adrenergic receptor in neurodegenerative diseases.