Protein mass spectrometry 2002
(BMG 744)
Course will be held on Tuesdays and Fridays 9 - 11 am in the McCallum Building, 4th floor conference room (401)
Schedule
| Date | Lecturer | Topic |
|---|---|---|
| Jan 4 | S. Barnes | Introduction to course - chemistry of biologically active molecules - transfer of proteins into the gas phase; Pros and Cons of ESI, MALDI-TOF and ion traps [PDF File] |
| Jan 8 | Barnes/MS Staff | Peptide analysis by mass spectrometry; capillary LC-MS; MALDI-TOF analysis; introduction to peptide sequencing by MS of proteins [PDF File] |
| Jan 11 | C-C. Wang | Applications of CE-MS and other nanomethods to biology |
| Jan 15 | H. Kim | 2D-proteomics and mass spec |
| Jan 18 | Barnes/Brookes | Protein Complexes [PDF File] |
| Jan 22 | MS Staff | On-instrument protein analysis and peptide sequencing by MS |
| Jan 25 | A. Safavy | Chemical modifications of proteins - analysis by MALDI |
| Jan 29 | Student presentations on peptide analysis by MS | |
| Feb 1 | C. Cassady (UA) | Ion molecule reactions in the gas phase usingFT-MS - applications to peptide sequencing |
| Feb 5 | D. Muddiman (VCU) | FT-MS and proteomics |
| Feb 8 | P.Prevelige | Use of H-D exchange to probe protein structure |
| Feb 12 | S. Barnes | Use of mass spectrometry in enzymology |
| Feb 15 | Students Presentations | |
| Feb 19 | S.Barnes | Identifying protein - phosphorylation [PDF File] |
| Feb 22 | R. Orlando (Univ. Georgia) | Identifying protein - glycosylation |
| Feb 26 | S. Barnes | Integration of genomics, proteomics and bioinformatics [PDF File] |
| Mar 1 | S. Barnes | NO - CLASS |
| Mar 5 | S. Barnes | Future of mass spectrometry in the analysis of mutational hotspots and of large DNA molecules |
| Mar 8 | Student presentations |