Protein mass spectrometry 2005
(BMG 744)

Course will be held on Tuesdays and Fridays 9 - 11 am in the McCallum Building, 4th floor conference room (401)


Date Lecturer Topic
Jan 4 S Barnes/H Kim The world of proteins - beyond genomics [PDF File]
Jan 7 H. Kim The proteome, proteomics and where to start
Jan 11 C. Fenselau
(U. Maryland)
12 Noon seminar - Volker Hall room C - required attendance
Jan 14 M Niemann Techniques of protein separation [PDF File]
Jan 18 H Kim Protein separation by electrophoresis and other 2D-methods [PDF File]
Jan 21
Student presentations
Jan 25 S Barnes Mass spectrometry of proteins and peptides: principles and principal methods ( PDF File )
Jan 28 S Barnes MALDI of proteins and peptide mass fingerprinting; LC analysis and peptide sequencing (PDF File )
Feb 1
Class demo of methods
Feb 4
Mid-term exam
Feb 8 A Loraine Connecting proteomics into bioinformatics ( PDF File )
Feb 11 G Page Statistical issues in proteomics and mass spectrometry ( PDF File )
Feb 15 S Barnes Qualitative and quantitative burrowing of the proteome
Feb 18
Student presentations
Feb 22 T Townes Analysis of protein-protein interactions by affinity purification
Feb 25 P Prevelige Liquid phase protein structure and protein-protein surface mapping
Mar 1 S Barnes Enzymology, proteomics and mass spectrometry ( PDF File,   Paper I       Paper II )
Mar 4   Student presentations
Mar 8 S Barnes/S Wang Tissue and fluid proteomics ( PDF File )
Mar 11 H Kim Application of proteomics to the brain proteome
Mar 15 S Bailey The mitochondrial proteome ( PDF File )
Mar 18
Final exam