Download PDF of Pilot Grant Announcement

UAB’s Nathan Shock Center of Excellence in the Basic Biology of Aging announces the availability of pilot/feasibility (P/F) project awards for investigators with a research focus on the comparative biology and/or energetics of aging and having the goal of future funding from the National Institutes of Health.

The projects must utilize one or more of the three research cores of the UAB Shock Center, which  are briefly described below. Applicants should contact the Research Development Core (contact information below) for guidance about the eligibility of their project and to be directed to the proper Research Cores to support their application. Budgets are generally less than $10,000 although larger budgets may be considered after consultation with Core leaders and/or co-leaders. Awards are for 1 year. Applications from institutions outside of the UAB are particularly encouraged.

Research Focus and Eligibility

The P/F studies may focus on any area of aging research that can be supported by our cores, with priority given to those examining comparative biology and/or energetics of aging.

The awards are intended to support faculty level scientists to obtain extramural funding for aging research. We particularly encourage applications from New Investigators (as defined by NIH) or established investigators new to aging research, and/or who are pursuing an entirely new direction in the field. P/F awards may be made to senior, accomplished post-doctoral fellows who are preparing to transition to faculty positions. Post-doctoral fellows should inquire with the RDC leaders prior to preparing an application, and their applications will require a letter of support from their PI along with a mentoring plan. Applicants new to aging biology research should identify a faculty mentor, with a strong record in the field, who is willing to serve as a mentor. Priority will be given to applications that demonstrate close relevance to the Shock Center mission and likelihood of future R01 funding.

Basic Alzheimer's disease studies are eligible if they contain a clear aging and/or energetics focus. Applicants must utilize the Shock Center Research Cores, which are described below and in the About Us section of the website.

Deadlines and Application Instructions

Application due dates in 2018 are January 1, April 1, July 1, and November 1. Funding period: One year from award date.

Applications must include:

  • The hypothesis and specific aims of the project (one page).
  • No more than one page of figures and figure legends.
  • Additional pages allowed for important references.
  • A one-paragraph statement (no more than half a page) of how this research will impact your future directions in aging research.
  • The Shock Center Core and Microbiome Core resources needed, including sample number if applicable and approximate time frame (half a page).
  • Current NIH-style biosketch including other support (up to five pages).

Applications should be submitted in pdf format to the Research Development Core, Dr. John Hartman (This email address is being protected from spambots. You need JavaScript enabled to view it.). Applicants are strongly encouraged to contact the Research Development Core leadership (contact information below) as a first step toward preparing an application.

UAB Shock Center Cores

  • Research Development Core: Thomas Buford (This email address is being protected from spambots. You need JavaScript enabled to view it.), Leader; Christy Carter (This email address is being protected from spambots. You need JavaScript enabled to view it.), Co-Leader; and John Hartman (This email address is being protected from spambots. You need JavaScript enabled to view it.), Co-Leader. The RDC administers the Pilot Grant Program and is the primary point of contact for interested applicants. Initial inquiries, questions about the application process, and final applications should be directed to the RDC.
  • Comparative Organismal Energetics Core: Tim Nagy (This email address is being protected from spambots. You need JavaScript enabled to view it.), Leader. This core provides state-of-the-art instrumentation and analyses for quantifying energy balance and body composition in diverse animals, including measures of energy expenditure (via indirect calorimetry), food intake, activity, and core body temperature. Body composition analyses can be performed on living and dead animals. Learn about their full list of services and COEC fees.
  • Comparative Mitochondrial Health Assessment Core: Jianhua Zhang, (This email address is being protected from spambots. You need JavaScript enabled to view it.), Leader. This core offers state-of-the-art services to investigators to facilitate research and training on mitochondrial function and mitophagy as it relates to aging. The core provides expertise in molecular energetics and metabolomics techniques in a variety of species from yeast to mice. Learn about our full list of services and CMHAC fees.
  • Comparative Data Analytics Core: David Allison, (This email address is being protected from spambots. You need JavaScript enabled to view it.), Leader. This core provides consultation in study design, research proposal development, and data analysis, including traditional, specialized, and customized analytical methods for scientists performing research on the basic biology of aging. CDAC also conducts high-level statistical investigations of secondary data to answer questions about the comparative biology and energetics of aging. CDAC works with investigators to develop new analytical tools and offers training in statistical methods for the comparative biology of energetics as it relates to aging.
  • Microbiome/Gnotobiotic Animal Core: Casey Morrow (This email address is being protected from spambots. You need JavaScript enabled to view it.), Leader. This core is recently affiliated with the Nathan Shock Center, and is described at the UAB Comprehensive Cancer Center website.

For further information, contact the Research Development Core and explore the UAB Nathan Shock Center website.