|C. Roger White, Ph.D.
Director, Basic Science Section of the Division of Gerontology
Division of Geriatric Medicine and Palliative Care
Areas of Focus: Mechanistic properties of novel apolipoprotein (apo) A-I mimetic peptides
Dr. White has made major contributions in the field of HDL biology in recent years through studies that are defining mechanistic properties of novel apolipoprotein (apo) A-I mimetic peptides. He has shown that apoA-I mimetics reduce plasma content of cholesterol and lipidhydroperoxides in atherogenic models by improving the function of HDL particles and prevent inflammatory vascular injury associated with sepsis. His recent observation that apoA-I mimetic peptides can mediate reverse cholesterol transport while also serving as a reactive substrates for some oxidants has revealed the dual function nature of these novel therapeutic agents.
Dr. Roger White is currently an Associate Professor. He received his B.A. degree from Lake Forest College in Lake Forest, IL in 1978; and his M.S. degree in from University of Illinois, Urbana-Champaign, Illinois in 1984 and Ph.D. degree in 1989 also from the University of Illinois. Dr. Roger White received his postdoctoral training in the Vascular Biology & Hypertension Program at UAB and joined the faculty in the Division of Cardiovascular Disease at UAB in 1993.