Welcome to Biochemistry, Structural and Stem Cell Biology at UABThe Biochemistry, Structural and Stem Cell Biology (BSSB) program trains students to design and execute experiments to answer mechanistic questions in a broad range of disciplines. Three research areas are emphasized:
The laboratories affiliated with the “Biochemistry and Molecular Genetics” area of the BSB theme use a wide array of experimental approaches to answer important questions in diverse biological systems. To fully understand a biological system, one must define the system using detailed, quantitative approaches. This principal unifies the faculty associated with this research area. Whether investigating DNA repair and recombination in prokaryotic systems or disease progression in human systems, it is critical that the process be described in molecular detail.
We value the critical role that students play in academic research. Our goal is to providing our students with:
1. Effective mentoring in experimental and academic pursuits
2. World class facilities and equipment for the advancement of their research projects
3. Collegial and cohesive working environment, fostering growth and scientific maturation No one is born an expert in biochemistry. If you are curious and committed to a career in research, we are committed to providing the best possible training to help you reach your goals.
Welcome to Stem Cell Biology research at UAB. Research in Stem Cell Biology is a major focus of the Biochemistry and Structural Biology (BSB) graduate program faculty. Students interested in stem cell research will find a diverse group of BSB principle investigators ready to train them to become tomorrow’s leading scientists in the stem cell field. BSB faculty members are focused on understanding the mechanisms involved in stem cell self-renewal and lineage specification of adult and pluripotent stem cells. Somatic cell reprogramming, epigenetic regulation, directed differentiation, and stem cell therapies in preclinical disease models are all active areas of research. In addition to basic research on stem cells a major goal of BSB scientists is to translate the understanding of basic mechanisms into clinical applications. The close interactions of basic and clinical scientists in the program and throughout the UAB Medical Center provide unique opportunities to develop new therapies for inherited and acquired human disorders.
Currently, the Stem Cell Biology group at UAB is rapidly expanding with the establishment of the UAB Stem Cell Institute and the hiring of six new faculty members in 2011. The UAB Stem Cell Institute offers incoming students access to state of the art facilities, equipment, and instrumentation from flow cytometers to next generation sequencers. Please apply to pursue graduate studies in Stem Cell Biology by applying to UAB Biochemistry and Structural Biology Graduate Program.
We’re glad you’re interested in UAB Structural Biology! Students participating in UAB's world class structural biology program are exposed to a broad array of biophysical techniques used to address challenging biological problems at the atomic/molecular level. Our structural biology faculty members are drawn from departments across the entire campus and are a truly interdisciplinary group. They are highly regarded nationally and internationally and their trainees are similarly highly regarded and sought after.
Students enrolled in the structural biology program can participate in a range of structural biology based courses in addition to those available via the general GBS curriculum. Major structural biology facilities provide state-of-the-art equipment including high brilliance in-house X-ray generators, dedicated access to two powerful X-ray beamlines at the Argonne National lab’s Synchrotron facility, high-throughput nano-crystallization systems, ultra-high resolution NMR instrumentation, large computer clusters that support macromolecular modeling and in silico drug discovery, electron microscopes for high resolution cryo-electron microscopy and tomography, and each of the major mass spectrometry technologies to support most types of structural biology-related projects.
Faculty in each of these areas are dedicated to training students to become critical, independent thinkers who design and execute cutting edge experiments that answer critical biomedical questions in biomedical science. BSB students publish papers in the highest quality, peer-reviewed journals and successfully compete for postdoctoral positions at other premier academic institutions and companies around the world. The close interactions between basic and clinical scientists in the program and throughout the UAB Medical Center provides unique opportunities to develop new therapies for inherited and acquired human disorders.
Biochemistry and Structural Biology Graduate Theme Director:
|David Schneider, Ph.D.|
|Co-Director:||Thomas M. Ryan, Ph.D.|