Micro Theme-Specific Courses

GBS 748 Fundamentals of Microbiology (Yother) November 18 - December 22
Monday-Friday, 8-10a.m., BBRB 263
This course presents essential concepts of modern microbiology relevant to bacteriology, virology, immunology, microbial pathogenesis, and structural biology. Through lectures and class participation, students will receive the foundation necessary to undertake more specialized and advanced courses in microbiology. The class is open to all first-year students in GBS themes and other graduate programs. This class in an advanced course.


GBS 760 Prokaryotic Genetics and Molecular Biology (Niederweis/Yother)
 January 5 - February 2
Monday-Friday, 8-10a.m., BBRB 263  (Syllabus)
This course is designed to familiarize students with advanced knowledge in recombination, transcription, translation, regulation of gene expression, transport mechanisms and protein export. The students will learn the fundamental principles of how structural components of bacterial cells are built and how bacteria-specific metabolic pathways can be exploited by antibiotics. We will cover state-of-the-art technologies such as whole genome sequencing, microarray experiments, methods to analyze protein-protein interactions and the metabolome of bacteria. In this course, we emphasize the training of critical thinking and foster the ability of the students to design their own experiments to solve scientific problems in bacteriology. The goal of the course is to provide a strong foundation for advanced bacteriology classes and for doing research in any bacteriology lab.

GBS 762 Virology (Frolova) February 3 - March 2
Monday-Friday, 8-10a.m., BBRB 263  (Syllabus)
This course is designed to familiarize students with the general steps involved in viral lifecycles and use this knowledge as a framework for understanding the similarities and differences in the lifecycles of (+) and (-) stranded RNA viruses, DNA viruses, and retroviruses. The course also covers the role of viruses in oncogenesis, the origin and evolution of viruses, the innate immune response to viral infections, and the development of antiviral chemotherapeutics. The goal of the course is to provide a strong foundation for advanced virology classes and to provide students with enough background in virology to be comfortable teaching in a college level microbiology class.

GBS 763 Microbial Pathogenesis (Briles) March 3 - 30
Monday-Friday, 8-10a.m., BBRB 263
The course in Bacterial Pathogenesis contains introductory lectures that provide an overview of major concepts including virulence factors, and host immune mechanisms. Most of the lectures describe the unique aspects of specific bacterial (and fungal) pathogens. Although many of the most important medical pathogens are covered, the course focuses especially on those bacterial and fungal pathogens studies most intensively at UAB. Each week students will be given a quiz based on the lectures of the preceding week. To answer the questions, an understanding of the lecture material will be needed. The questions are designed to help the students thinking about hypotheses and concepts in Bacterial Pathogenesis. The final grade in the course will be based on these quizzes and the student participation in discussions.
TEXT:  Todar's Online Textbook of Bacteriology

GBS 768 Communicating Science: Reading, Writing, and Presenting (Thompson) March 31 - April 27
Monday-Friday, 8-10a.m., BBRB 263
This first year graduate level course will teach students how to make formal scientific oral presentations and how to write a paper for publication in a scientific journal.

GBS 764 Structural Biology (Prevelige)  Not offered Spring 2015
Structural biology is central to understanding the function of biological macromolecules and is relevant to all fields of modern biological science. This course will provide a basic introduction to the elements of structural biology, including the levels of protein structure (primary, secondary, tertiary, quaternary), the basis of structure determination by X ray crystallography, NMR, and cryo-electron microscopy, and will explore the structure/function relationships in select systems.