Current Research

MASTERS Trial 

Metformin to Augment Strength Training Effective Response in Seniors

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Strength exercise training is the most effective intervention identified to combat loss of muscle function with advancing age; however, the response to exercise is blunted and highly variable in older adults.  This randomized, placebo-controlled trial - a collaboration between two major academic medical centers (University of Kentucky and University of Alabama at Birmingham) - is designed to determine if the addition of a medication (Metformin) will improve the effectiveness of strength training in older adults.  The overall goal is to establish a low cost, personalized approach to prevent frailty in the elderly.

Participants:  65+ years of age; no history of diabetes; no intensive strength training during the past three years; access to transportation; must meet all other inclusion and exclusion criteria.

Benefits:  Supervised exercise training 3 days per week for 14 weeks with certified trainers in a clinical research setting; free assessments of health and functional status, body composition, and fitness; opportunity to play a pivotal role in Biomedical research that will advance personalized exercise medicine for older adults.


Click here for details and form



Head, Neck, and Breast Cancer
    
The UAB Center for Exercise Medicine, UAB Division of Otolaryngology, and UAB Department of Radiation Oncology are sponsoring a pilot study for head/neck or breast cancer patients evaluating the effects of radiation and chemotherapy on muscle mass and function/strenth, and the effects of a strength training rehabilitation program.  Each participant will exercise under full supervision three days per week at UAB.
To participate in this study, candidates should meet the following criteria:


·        Adults 19 years or older with Head, Neck, or Breast cancer
·        Able to attend 3 exercise sessions per week at UAB for 8 weeks
·        Must pass pre-exercise screening

For more information, please contact Craig Tuggle at 205-975-6231 or by email at
tugg12@uab.edu.


Spinal Cord Injury
The Center for Exercise Medicine (UCEM) Core Muscle Research Laboratory are sponsoring a novel combination exercise program vs. HP diet on body composition and metabolic health in SCI individuals with type 2 diabetes or impaired glucose tolerance.  Each participatant will exercise under full supervision three days per week at UAB. 
To participate in this study, candidates should meet the following criteria:


·        Individuals must have complete or incomplete spinal cord injury (tetraplegia or paraplegia)
·        Able to attend 3 exercise sessions per week at UAB for 8 weeks
·        Must be manual wheelchair users

For more information, please contact Ceren Yarar-Fiser at 205-996-7938 or by email at cyarar@uab.edu.