obgyn research

The department of Obstetrics and Gynecology established the Center for Women's Reproductive Health (CWRH) 1993 with the mission to conduct research aimed at improving the reproductive health of all women, especially minority and under-served women and their families, and to facilitate collaboration between UAB researchers and developing scholars interested in women's reproductive health issues.

The CWRH works in conjunction with the department of Obstetrics and Gynecology and many other UAB entities - including the Schools of Health Related Professions, Medicine, Dentistry, and Public Health - to accomplish its mission.  Part of this mission includes recruiting researchers interested in women's reproductive health issues into a more formal research collaboration.

The center also supports extensive education and graduate training programs for young investigators and scientists to develop research careers in the area of women's health.

The CWRH is physically located just a few blocks from the UAB Women and Infants Center, and is comprised of three floors housing administrative and meeting space, dedicated research and lab space, and ample multi-disciplinary clinical space.

The Center's clinical research focus includes the following:

  • Improvement of infant mortality and pregnancy outcomes (particularly in disadvantaged and minority populations as well as in  sub-Saharan Africa); prevention of premature labor;
  • Infectious disease in pregnancy and its relationship to premature labor;
  • Study of treatment strategies and their cost effectiveness in gynecological disorders such as infertility, dysfunctional uterine bleeding, pelvic inflammatory disease, menopause, pelvic relaxation/incontinence, and abnormal pap smears; study of treatment strategies aimed at cancerous gynecological disorders;
  • Development of novel therapeutics in reproductive tract cancers; prevention of maternal to fetal HIV transmission;
  • Evaluation of smoking cessation interventions; longitudinal studies aimed at nutrition status and intrauterine growth retardation and its relationship to child development; and cancer prevention and control.

The CWRH is also involved in basic/translational research, including extensive research activities in collaboration with the Division of Gene Therapy. These activities include the development of novel strategies to accomplish gene therapy for ovarian cancer and rapid implementation of these strategies into clinical protocols.

In addition to research and clinic care the Center is involved in a number of service programs. The Colposcopy Clinic provides follow-up of abnormal pap smears for women referred by county health departments throughout Alabama, as well as consultation/medical directorship of their patient screening protocols.  Patients of the Center for Genitourinary Disorders are served by a team of urogynecologists, urologists, geriatricians, immunologists, health behaviorists, and nurses.

The department and CWRH are currently recruiting participants for research in the following divisions:

  • Maternal-Fetal Medicine
  • Urogynecology Care and Pelvic Reconstruction Surgery
  • Women’s Reproductive Healthcare