Changes to a key protein amplified its natural ability to counter kidney disease, according to UAB research. The team now will work to confirm those results and conduct toxicity and dosing studies that would need before they could conduct human clinical trials. The study was published in the journal Nature Medicine.
Renowned expert named inaugural director of UAB Informatics InstituteJames J. Cimino, M.D., will lead UAB's new Informatics Institute, which was established in June 2014. Cimino, who previously was the chief of the Laboratory for Informatics Development at the NIH Clinical Center and a senior scientist at the National Library of Medicine, is a national leader in the field of biomedical informatics and co-editor of the most influential textbook on the subject.Research enters data-driven eraDuring the past few years, technological innovations have opened up an entirely new way to approach scientific questions. Data-driven research starts with massive information sets â€” the genomic profiles of thousands of patients, for example, or millions of spam emails â€” and then searches for emerging patterns in that data. In the latest issue of the U.S. Chamber of Commerceâ€™s "Business Horizon Quarterly", UAB President Ray Watts, M.D., explains the way data-driven research at UAB is being applied to find novel treatments for disease, create new products and businesses and train the next generation of innovation-savvy students.Common blood-pressure drug reverses diabetes in mice, human trials to beginFulbright scholar here to improve health care in Ukraine
Iryna Mazhak, Ph.D., a Fulbright Visiting Scholar from Ukraine, is developing a medical sociology course and textbook materials during her nine months at UAB. No such course or textbook exists in her homeland, she says.How safe are you on the Internet?Participate in a brief, large-scale survey of Internet users that will help UAB researchers design strong authentication systems for securing information privacy.NIH pilot to help move heart-graft technology to market fasterA UAB-led team is one of 24 to receive an inaugural NIH Innovation Corps grant that will enable them to develop a much better understanding of the commercial landscape for a vascular graft technology and significantly refine its plan for bringing it to market.Competition produces creative proposals to reduce obesityNine researchers are halfway to the prize money for their winning entries in the annual Creativity is a Decision Awards. To collect prize money, winners must submit their proposal to an extramural sponsoring authority by Nov. 5.Study to examine how healthy moms pass deadly bacteria to infantsNarayana Sthanam, Ph.D., professor of structural biology, is working to discover how GBS escapes the motherâ€™s natural defense systems in hopes that knowledge will lead to a therapeutic intervention. His research is funded by a $1 million R01 grant from the NIH/NIAID.UAB enrolls nationâ€™s first patient in Phase III drug trial for preeclampsiaIf successful, the drug would be a significant clinical breakthrough for reducing pre-term births and infant mortality.Friedman committed to improving therapies for children with brain cancer
Gregory Friedman, M.D., is working to combat medulloblastoma â€” the most common malignant pediatric brain tumor â€” using genetically altered viruses that kill cancer cells and leave normal cells untouched.