Changes to a key protein amplified its natural ability to counter kidney disease, according to UAB research. The team now will work to confirm those results and conduct toxicity and dosing studies that would need before they could conduct human clinical trials. The study was published in the journal Nature Medicine.
NIH pilot to help move heart-graft technology to market fasterA UAB-led team is one of 24 to receive an inaugural NIH Innovation Corps grant that will enable them to develop a much better understanding of the commercial landscape for a vascular graft technology and significantly refine its plan for bringing it to market.Competition produces creative proposals to reduce obesityNine researchers are halfway to the prize money for their winning entries in the annual Creativity is a Decision Awards. To collect prize money, winners must submit their proposal to an extramural sponsoring authority by Nov. 5.Study to examine how healthy moms pass deadly bacteria to infantsNarayana Sthanam, Ph.D., professor of structural biology, is working to discover how GBS escapes the motherâ€™s natural defense systems in hopes that knowledge will lead to a therapeutic intervention. His research is funded by a $1 million R01 grant from the NIH/NIAID.UAB enrolls nationâ€™s first patient in Phase III drug trial for preeclampsiaIf successful, the drug would be a significant clinical breakthrough for reducing pre-term births and infant mortality.Friedman committed to improving therapies for children with brain cancer
Gregory Friedman, M.D., is working to combat medulloblastoma â€” the most common malignant pediatric brain tumor â€” using genetically altered viruses that kill cancer cells and leave normal cells untouched.New approach for HPV screening can be effective in developing countriesThe first HPV and cytology study conducted in rural Nepal suggests self-collected samples may offer effective screening for the deadly infection.No evidence eating fruits and vegetables promotes weight-loss
Eating more fruits and vegetables is good for a number of reasons, but weight-loss isnâ€™t necessarily one of them, UAB researchers say.Simulator to help children learn to cross streets safelyProfessor David Schwebel, Ph.D., developed a new virtual-reality system to help reduce pedestrian injuries and deaths among children.Discovery of how brain tumor cells move points to possible therapyResearch that sheds light on the way gliomas migrate and cause brain tumors may reveal a new avenue to kill them. The findings, published June 19 in Nature Communications, show that gliomas disrupt normal neural connections and hijack control of blood vessels â€” which may open the door for chemotherapy.Informatics Institute will bridge big data and biomedical researchA new initiative in the School of Medicine will deliver the data to help drive research and advance discoveries.