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The mission of the UAB Human Neuromodulation Laboratory is to advance knowledge to facilitate comprehensive care for patients with movement disorders such as Parkinson’s disease, tremor, dystonia, and other movement disorders.

The overall scientific focus of the lab is to better understand how deep brain stimulation (DBS) interacts with human brain circuits that control movement. DBS is a remarkable therapy that delivers electrical impulses to target areas in the brain, including the subthalamic nucleus (STN), globus pallidus internus (GPI), and ventral intermediate nucleus of the thalamus (VIM), to improve motor symptoms from Parkinson’s disease and other movement disorders. Our multidisciplinary team consists of personnel from neurology, neurosurgery, neuropsychology, radiology, neurobiology, engineering, and biostatistics.

The lab has active research programs that focus on advancing knowledge on movement disorders pathophysiology, DBS mechanism of action, and novel techniques using emerging device and imaging technologies. Our clinical team provides a variety of services that include neurological evaluation, disease management, deep brain stimulation surgery, and postoperative programming.