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Knockout of TXNIP improves diabetes-associated hyperglycemia and hyperglucagonemia.
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Beta-cell regeneration– an area of research that may feel more science fiction than science today. But, it is a keen area of interest for UAB Comprehensive Diabetes Center (UCDC) researchers using cell biology approaches to discover curative treatments for Type[…]
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Published results suggest the COVID-19 pandemic exacerbated the slow increase in pediatric Type 2 diabetes.
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Department of Nutrition Sciences Professor, Tim Garvey, M.D., and team set out to investigate the effects of both cardiometabolic disease (CMD)–such as obesity and type 2 diabetes–and social determinants of health (SDoH)–like educational attainment, social vulnerability index, rurality, and healthcare[…]
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Researchers at the University of Alabama at Birmingham have recently discovered a rise in new-onset type 2 diabetes among Alabama youth during COVID-19 pandemic. Particularly, they found that the increase in cases disproportionately affected Medicaid enrollees and males.
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Carbohydrates are directly linked to the development of Type 2 diabetes, but a higher-carb diet is underused in research models.
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Many researchers are pursing treatment options for diabetes—a disease characterized by high glucose levels— through approaches that increase insulin. However, there are two pancreatic hormones that play a critical role in regulating glucose levels, insulin, produced by pancreatic beta cells,[…]
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In a new series, the UAB Comprehensive Diabetes Center (UCDC), a leader in the field of diabetes research, will highlight its dynamic faculty and trainees. The UCDC has members from across several schools and departments at UAB. Diabetes research capabilities[…]
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As cool mornings begin to break up the summer heat and fall quickly approaches, the UAB Comprehensive Diabetes Center (UCDC) is partnering with the UAB Heersink School of Medicine and campus departments to identify and recruit top talent in the[…]
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U.S. News & World Report (USNWR) recently ranked UAB Hospital as the best hospital in Alabama, naming several of its specialties as top-ranking in the nation as well. Of the rankings, UAB Hospital’s endocrinology and diabetes specialty came in a[…]
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Seven questions for Michael Sloane, Ph.D., on his seven-year quest to race on every continent.
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UAB Heersink School of Medicine staff council representatives have officially been named for the 2022-2024 term. See who has been elected to represent you!
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Dr. Guanlan Xu, corresponding author. Behold the beta-cell: a cell found in the islets of Langerhans in the pancreas that is responsible for all the insulin production and secretion needed to maintain normal blood sugar levels.
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The Council on Basic Cardiovascular Sciences, known as the BCVS, is one of the largest councils at the American Heart Association, and it is one of the largest organizations in cardiovascular sciences globally, with more than 4,700 members.
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This therapy, using sustained release of nitric oxide, may be a novel, efficient and safe way to prevent and treat multiple metabolic diseases.
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Benefits of the blood pressure medication verapamil include delayed disease progression, lowered insulin requirements and preservation of some beta cell function.
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Record $95 million Heersink lead gift to advance strategic growth and biomedical innovation.
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Use of the diabetes drug metformin — before a diagnosis of COVID-19 — was associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes.
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These lipids may act as a biomarker for Type 1 diabetes and offer a therapeutic target to prevent the disease.
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The drug candidate is a non-toxic small molecule that given orally effectively rescued mice from models of Type 1 and Type 2 diabetes.
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This award recognizes Robert Oster’s numerous statistical contributions to UAB faculty, staff and students.
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Impacting the health and well-being of a community is a cornerstone of UAB’s strategic plan and has been recognized globally by Times Higher Education.
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John Kearney, Ph.D., Distinguished Professor in the Department of Microbiology, will be honored for 45 years of service to UAB during the annual Service Awards banquet March 6.
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This suggests the possibility of cross-talk that heightens pathogenesis in Type 1 diabetes.
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Three School of Medicine faculty projects were recently funded as AMC21 2019 Multi-PI awardees.
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The biomarker can identify beta cell death in children and adults with recent-onset Type 1 diabetes and in antibody-positive at-risk subjects before disease onset.
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UAB and Children’s of Alabama have named the new director of Pediatric Endocrinology.
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UAB nutrition researchers are conducting a new study on Type 2 diabetes and addressing the disproportionate complications experienced by African American patients.
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A new study from UAB describes the impact of a peer coach intervention on hospitalizations and emergency room visits for individuals with diabetes and depression.
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Some 652 participants across four states will be recruited to test the effects of exercise and diet interventions in underserved cancer survivors.
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A gene called TXNIP was the answer, and it led to a drug called verapamil and a successful diabetes trial.
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Significant novel findings published by UAB researchers established verapamil as a successful therapeutic approach to target loss of beta cell function caused by Type 1 diabetes.
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Inhibition of this microRNA might improve response to newer diabetes drugs, such as Byetta, Victoza, Trulicity, Januvia, Onglyza and Tradjenta.
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Inhibition of this microRNA might improve response to newer diabetes drugs, such as Byetta, Victoza, Trulicity, Januvia, Onglyza and Tradjenta.
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A multidisciplinary research team at UAB looks to address obesity as it is genetically passed from mother to child.
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Recruitment for the trial continues as Myers discusses the benefits she received from participating and the knowledge she has gained to take control of her health care.
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Recruitment for the trial continues as Myers discusses the benefits she received from participating and the knowledge she has gained to take control of her health care.
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Lead author of paper published in Diabetes Research and Clinical Practice journal says, while causal relationship cannot be inferred, findings are “absolutely encouraging.”
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Lead author of paper published in Diabetes Research and Clinical Practice journal says, while causal relationship cannot be inferred, findings are “absolutely encouraging.”
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Many patients diagnosed with type 1 diabetes as adults do not fit the standard profile for a diabetes diagnosis; they are younger, are relatively fit and have little if any belly fat.
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Many patients diagnosed with type 1 diabetes as adults do not fit the standard profile for a diabetes diagnosis; they are younger, are relatively fit and have little if any belly fat.
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Three-year grant establishes consortium to better organize and support collaborative research related to the loss of functional beta cell mass in type 1 diabetes.
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Three-year grant establishes consortium to better organize and support collaborative research related to the loss of functional beta cell mass in type 1 diabetes.
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Looking forward to a promising 2015, UAB News revisits some top stories of 2014.
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The “repurposing of verapamil as a beta cell survival therapy in type 1 diabetes” trial will test an approach different from any current diabetes treatment.
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The “repurposing of verapamil as a beta cell survival therapy in type 1 diabetes” trial will test an approach different from any current diabetes treatment.
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Learn more about causes, therapies and training during UAB Comprehensive Diabetes Center’s annual research day.
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African-Americans have higher obesity rates than do whites, and while socioeconomic status is often believed to be the root cause, a new UAB study suggests other factors should be considered.
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Counting carbs, exchanging candy for other treats and saving it for dessert are all alternatives for parents to consider.
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EndoBarrier trial testing liner that forms barrier between food, portion of intestine to help obese people with uncontrolled type 2 diabetes
