Researchers in the Department of Family and Community Medicine contribute to studies across a variety of institutions and academic departments.
PREVENTABLE: Pragmatic Evaluation of Events and Benefits of Lipid-lowering in Older Adults
The largest randomized trial ever conducted exclusively in older adults, PREVENTABLE tests the effectiveness of statins for the prevention of new dementia or persisting disability. The study will fill a key evidence gap regarding:
- The usefulness of statins for prolonging healthy life years and primary cardiovascular prevention in adults over age 75, especially in the setting of multiple chronic conditions.
- The usefulness of statins to address other common conditions such as mild cognitive impairment/dementia, physical disability, or heart failure with preserved ejection fraction (HFpEF) may be improved by an effective vascular prevention.
Pragmatic studies like PREVENTABLE are particularly ideal for older adults.
PREVENTABLE will follow up to 20,000 study participants by reviewing their health records and through a phone call or a home visit. Researchers will also mail study drug directly to a participant's home.
Other Projects
-
The Exercise and Physical Activity Collaborative Team (ExPACT)
Co-investigator: Taylor Buchnan, Ph.D.
Funding source: National Institute of Arthritis and Musculoskeletal and Skin (NIH Common Fund) -
ACES - ACE Inhibitors Combined with Exercise for Hypertensive Seniors
Co-investigator: Taylor Buchanan, Ph.D.
Funding source: National Institute on Aging (NIH Common Fund) -
UAB/Tuskegee Faculty Institutional Recruitment for Sustainable Transformation (UAB/TU FIRST) Partnership
Faculty member: Taylor Buchanan, Ph.D.
Funding source: National Cancer Institue (NIH Common Fund) -
Feasibililty of High-Intensity Interval Training in Older Adults with HIV and Co-occurring Hypertension
Co-investigator: Taylor Buchanan, Ph.D.
Funding source: HIV & Aging Research Consortium (No award)