In a report published in Nature Communications, Michael Niederweis, PhD and colleagues identify key secretion systems used by Mycobacterium tuberculosis (Mtb) in pathogenesis, which makes them candidate targets for therapeutics. Read more

Jeanne Marrazzo, M.D., MPH, (Professor and Director) and Nathan Erdmann, M.D., Ph.D., (Assistant Professor) will co-lead the Deep South SARS-COV-2 Recovery Cohort, along with Dr. Emily Levitan (SOPH), as part of the nationwide RECOVER initiative, which is projected to receive $17 million from NIH. Read more

Clinical Immunology and Rheumatology professors Winn Chatham, M.D., Troy Randall, Ph.D., and colleagues, in collaboration with Emory University and the Medical University of South Carolina, have received a $3 million Global Team Science Award from the Lupus Research Alliance to work on better understand systemic lupus erythematosus in Black women, a patient population with the highest concentration of disease severity. Read more

Research published in the journal Cell Reports and led by Carlos Orihuela, Ph.D., and David Briles, Ph.D., professor and professor emeritus in the UAB Department of Microbiology, shows that S. pneumoniae adheres to dying lung cells, worsening secondary infection following flu. Read more 

Craig Maynard, Ph.D., assistant professor in the Department of Pathology, and his team, including first author Ashley Landuyt, Ph.D., former student in the Immunology Theme of the GBS program and supported by the Immunology T32, were recently published in PNAS for their study “ICOS ligand and IL-10 synergize to promote host–microbiota mutualism.” Read more

UAB researchers, led by Frances E. Lund, PhD, Professor and Chair of the Department of Microbiology, report additional preclinical evidence of the potency of a single-dose, intranasal COVID-19 vaccine candidate AdCOVID - created by Altimmune Inc., a Maryland-based clinical-stage biopharmaceutical company. A single intranasal dose provided sterilizing immunity in the lungs of vaccinated animals. Read more

In their study published in the journal Gastroenterology, Charles O. Elson, III, MD and co-first authors Katie Alexander, Ph.D., and Qing Zhao, M.D. were first to report that Crohn’s disease patients have specific IgG antibodies to human bacterial flagellins. Read more

UAB lab led by Sixto Leal, MD, PhD tracks risky COVID-19 variants Read more

Jacob Files, a graduate student in the UAB M.D.-Ph.D., Medical Scientist Training Program, Assistant Professor Nathan Erdmann, MD, PhD and Professor Paul Goepfert, MD from the UAB Division of Infectious Disease, report sustained cellular immune dysregulation in individuals recovering from COVID-19. Read more

Better tests, cheaper vaccines: Antibody expert Moon Nahm, MD, professor in the Division of Pulmonary, Allergy and Critical Care and director of UAB's Bacterial Respiratory Pathogen Reference Laboratory and the World Health Organization Pneumococcal Reference Laboratory, turns to COVID-19. Read more