Altered excitability is seen in brain neurons in epilepsy, depression, drug addiction and other disorders, and this discovery may offer a potential therapeutic target.
The ecRNAs appear to act in memory formation, and may offer a new therapeutic approach to neuropsychiatric diseases.
John J. Hablitz, Ph.D., has been a leader in the department since its establishment in 1996.
Researchers have proposed a model that resolves a seeming paradox in one of the most intriguing areas of the brain, exploring how immature granule cells in the dentate gyrus appear able to enhance pattern separation due to lesser synaptic connectivity than mature cells.
Grant named in memory of Kindal Kivisto will help advance research, treatment of Pitt Hopkins Syndrome.
UAB researchers find that epigenetic changes associated with chronic obesity alter expression of memory-related genes in the brain.
Five faculty members in the School of Medicine have been named the 2016 class of James A. Pittman Jr., M.D., Scholars, a program organized to recognize the contributions of junior faculty and support the retention of highly competitive scientists and physician-scientists.
The Alzheimer’s plaques that accumulate around brain cells also congregate along the walls of blood vessels, according to UAB research, and that may contribute to cognitive issues.
David Sweatt, Ph.D., the Evelyn F. McKnight Endowed Chairman of the Department of Neurobiology and the director of the Evelyn F. McKnight Brain Institute, has been named director of the Civitan International Research Center.
A UAB researcher focusing on the epigenetics of drug abuse wins a significant funding award from the National Institutes of Health.