Until now, no toxin had been found in 132 years of study for the deadly pathogen Mycobacterium tuberculosis, which infects 9 million people a year and kills more than 1 million. The novel toxin induces necrotic cell death of macrophages to help the tuberculosis pathogen escape and spread to other cells.
Phillip D. Smith, M.D., has been awarded a two-year, $200,000 grant from the DeGregorio Family Foundation to study the bacteria in children’s stomachs that potentially protects them from stomach cancer.
Macrophage cells require agility to scavenge and digest dead cells and prevent an immune response to self. In lupus, the macrophages lose that agility.
UAB has established the third multidisciplinary comprehensive clinic in the world for transverse myelitis, a rare spinal cord disease.
The ability to build a mimic of the interferon-interferon receptor complex allows a hunt for unique monoclonal antibodies.
Jorge Galán, latest in a long list of prestigious Marx lecturers, will speak on the molecular pathogenesis of typhoid fever.
Five faculty members in the UAB School of Medicine have been named the inaugural James A. Pittman Jr., M.D., Scholars, a new program organized to recognize the contributions of junior faculty.
Precious time is lost waiting for laboratory test results for people battling this infection. With the help of medical device startup Kypha Inc., one UAB researcher’s work could change this.
The multi-project research targets key molecular steps of immune cell-fate decisions after virus infection.
A study reveals a potential new drug pathway target for battling Mycobacterium tuberculosis, or Mtb, the pathogen that causes tuberculosis.