Michael Soike, M.D.The UAB Department of Radiation Oncology recently launched a unique osteoarthritis program that uses low-dose radiation therapy as an additional treatment option for patients with debilitating joint pain. Delivered over six short sessions following an initial consultation, the therapy aims to reduce inflammation and alleviate discomfort without the side effects typically associated with cancer radiation treatments.
Conventional treatments for osteoarthritis include physical therapy, nonsteroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen or Mobic, corticosteroid injections, and joint replacement surgery. While these options can help, many patients continue to experience pain and limited mobility. Low‑dose radiation therapy provides another tool for physicians and patients seeking relief.
“The best data and results from low‑dose radiation for osteoarthritis come from a treatment regimen that involves seven total visits,” said Michael Soike, M.D., associate professor in the Department of Radiation Oncology. “The first visit is a consultation, which lasts 30 to 40 minutes. We review the reasons why we would use radiation for osteoarthritis and measure the joints that need to be treated. Then patients return for six treatments delivered twice weekly, each lasting 10 to 15 minutes.”
Soike added that the process is painless and similar to getting a dental X‑ray or CT scan. Unlike cancer treatments that require high doses of radiation, this therapy uses about one‑twentieth of that amount, eliminating side effects such as hair loss or skin irritation. Research suggests that low doses of radiation decrease inflammatory markers within the joints, helping them “reset” to a healthier state. While it does not regrow cartilage, it can alleviate discomfort.
Since launching just over a year ago, the program has treated about 30 patients, with 60 to 75 percent reporting reduced pain that lasts months to years.
“My hope is that these patients with debilitating arthritis are able to strengthen their muscles, get involved in physical therapy, and in the long run, stabilize the joints and have a better quality of life,” Soike said. “It is not a magic bullet, but it is another tool in our arsenal that can be very helpful.”
In addition to offering treatment at The Kirklin Clinic at Action Road, the program recently expanded to Russell Medical Center in Alexander City, Alabama, making this therapy more accessible to patients outside Birmingham. Designed to be affordable and covered by insurance, the program helps ensure cost is not a barrier to care.
Looking ahead, clinicians plan to review patient outcomes and present findings at a national conference later this year. By combining advanced technology with a patient‑centered approach, UAB continues to offer innovative care for managing joint pain and improving quality of life.