obgyn research

The department of Obstetrics and Gynecology established the Center for Women's Reproductive Health (CWRH) 1993 with the mission to conduct research aimed at improving the reproductive health and survival of all women, especially minority and under-served women and offspring, and their families, and to facilitate interdisciplinary collaboration between UAB researchers and others and developing scholars interested in women's reproductive health.

The CWRH works in conjunction with the department of Obstetrics and Gynecology and many other UAB entities - including the Schools of Health Related Professions, Medicine, Dentistry, Engineering and Public Health - to accomplish its mission. Part of this mission includes recruiting researchers interested in women's reproductive health into formal research collaborations.

The center also supports extensive education and graduate training programs for young investigators and scientists to develop interdisciplinary research careers in the area of women's health.

The CWRH is physically located just a few blocks from the UAB Women and Infants Center, and is comprised of three floors housing administrative and meeting space, dedicated research and lab space, and ample multi-disciplinary clinical space.

The Center's clinical research focus includes the following:

  • Improvement of pregnancy outcomes and maternal and infant survival (particularly in disadvantaged and minority populations as well as in sub-Saharan Africa) by addressing the major causes of maternal and infant mortality including preterm birth, hypertensive disorders, infections, opioid abuse, obstetric complications and labor management
  • Global women’s reproductive health including HIV, malaria, hepatitis B infection, technology;
  • Study of treatment strategies and their cost effectiveness in gynecological disorders such as infertility, dysfunctional uterine bleeding, pelvic inflammatory disease, menopause, pelvic relaxation/incontinence, and abnormal pap smears; study of treatment strategies aimed at cancerous gynecological disorders;
  • Development of novel therapeutics in reproductive tract cancers; prevention of maternal to fetal HIV transmission;
  • Evaluation of smoking cessation interventions; longitudinal studies aimed at nutrition status and intrauterine growth retardation and its relationship to child development; and cancer prevention and control.

The CWRH is also involved in basic/translational research, including extensive research activities in collaboration with the Division of Gene Therapy. These activities include the development of novel strategies to accomplish gene therapy for sickle cell, ovarian cancer and rapid implementation of these strategies into clinical protocols.

In addition to research and clinic care the Center is involved in a number of service programs. The Colposcopy Clinic provides follow-up of abnormal pap smears for women referred by county health departments throughout Alabama, as well as consultation/medical directorship of their patient screening protocols. Patients of the Center for Genitourinary Disorders are served by a team of urogynecologists, urologists, geriatricians, immunologists, health behaviorists, and nurses.

The department and CWRH are currently recruiting participants for research in the following divisions:

  • Maternal-Fetal Medicine
  • Urogynecology Care and Pelvic Reconstruction Surgery
  • Women’s Reproductive Healthcare
  • Cancer prevention
  • Global health in Cameroon

Center Director

Alan TitaAlan T.N. Tita, M.D., Ph.D.
John C. Hauth, MD Endowed Professor and Vice Chairman

UAB Department of Obstetrics & Gynecology
1700 6th Ave South
Women & Infants Center Room 10270
Birmingham, AL 35233