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The UAB-TBIMS provides this website as an auxiliary resource for primary care of patients with TBI.The contents of this website were developed under a grant from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR grant number 90DPTB0029). NIDILRR is a Center within the Administration for Community Living (ACL), Department of Health and Human Services (HHS). The contents of this website do not necessarily represent the policy of NIDILRR, ACL, HHS, and you should not assume endorsement by the Federal Government.
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There is some evidence to support the efficacy and tolerability of electroconvulsive therapy (ECT), low-intensity magnetic field exposure, biofeedback, and acupuncture for treating depression after TBI. However, the weak study designs and small samples included in this research make these results highly preliminary. On the basis of five studies included in this review (1 on ECT, 2 on magnetic stimulation, 1 on biofeedback, and 1 on acupuncture) the review authors make the following recommendations:

  • A single study on the use of ECT provides some evidence supporting its use, but cognitive side effects need to be monitored closely. The authors of the study also recommend adapting ECT by using unilateral electrode placement and a lower frequency of applications. 
  • Magnetic stimulation, biofeedback, and acupuncture currently have inadequate evidence to support their use for reduction of depression in people with TBI.

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Treating Depression Following Traumatic Brain Injury: A Summary for Clinicians (PDF). Copyright © 2010 Model Systems Knowledge Translation Center (MSKTC). Based on Fann JR, Hart T, Schomer KG. (2009). Treatment for Depression Following Traumatic Brain Injury: A Systematic Review. J. Neurotrauma.2009 Aug 21. doi:10.1089/neu.2009.1091

800-UAB-MIST - 24-hour hotline for physicians to consult with a UAB specialist.


MD Learning Channel
Ask a Question
Feedback & Comments
PCPs & ADA Compliance


The UAB-TBIMS provides this website as an auxiliary resource for primary care of patients with TBI.The contents of this website were developed under a grant from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR grant number 90DPTB0029). NIDILRR is a Center within the Administration for Community Living (ACL), Department of Health and Human Services (HHS). The contents of this website do not necessarily represent the policy of NIDILRR, ACL, HHS, and you should not assume endorsement by the Federal Government.
NIDILRR