The microbiome refers to all the microorganisms (bacteria, fungi, archaea) that live within and on the body. Research has found differences between the gut microbiota of individuals with certain colorectal conditions, such as inflammatory bowel disease or colorectal cancer, and healthy controls. Studies have shown that intestinal bacteria may also play a role in healing after surgery. Our research group aims to better understand the mechanisms by which the microbiome may influence healing after colorectal surgery and the role it may play in surgical outcomes, such as anastomotic healing and leaks. This project is a collaboration between the UAB Division of Gastrointestinal Surgery and the UAB Microbiome Core.