Farewell to the 2018 Chiefs!
The Department of Urology enjoyed a wonderful evening at the Birmingham Country Club celebrating the graduation of our three PGY-5 residents and two fellows.
- Dr. Patrick James Guthrie is headed to north Alabama to work at Decatur Morgan Hospital.
- Dr. Win Shun Lai is moving to Austin, Texas to practice at Baylor, Scott and White Medical Center.
- Dr. Erik Lars Wallin III is also headed to north Alabama and will be working at Cullman Regional Medical Center.
- Dr. Jubilee Tan is headed back to practice in Peoria, Illinois.
- Dr. Kyle Wood also completed his fellowship at UAB and will remain with the Department of Urology focusing his research and clinical endeavors on kidney stone disease.
Dr. Sunil Sudarshan won the Urology Faculty Teaching award for 2017-2018, and Dr. Vidu Yarlagadda (rising PGY-5) recieved the Resident Research Award. Congrats!
All of our graduated PGY-5 residents will be greatly missed. We wish them the best of luck on their future endeavors.
AUA Conference Recap
The 2018 American Urological Association conference was an eventful one for the UAB Department of Urology. Our faculty spent four days in San Francisco participating in innovative and educational programs that provided access to groundbreaking research, the latest clinical guidelines and the most advanced technologies in urology.
On Saturday evening, the department hosted an alumni reception at the Marriott Marquis where faculty and alumni enjoyed network over drinks and hors d'oeuvres.
Several of our faculty, residents and medical students presented posters, moderated sessions and provided key takeaways. Below are some highlights:
Dr. Dean Assimos presentations, posters, moderated sessions, etc.:
- Stone Disease: Basic Research & Pathophysiology II (co-moderated with Dr. Tanecia Mitchell)
- Surgical & Medical Stone Guidelines Update: A Case-Based Approach
- Session 5: The Future is Bright (ROCK Society)
- Gotta Wear Shades (ROCK Society)
Dr. Peter Kolettis presentations, posters, moderated sessions, etc.:
- Infertility: Therapy I
Dr. Tanecia Mitchell presentations, posters, moderated sessions, etc.:
- Stone Disease: Basic Research & Pathophysiology II (co-moderated with Dr. Dean Assimos)
- Take Home Messages: Basic Science (Benign)
Dr. Soroush Rais-Bahrami presentations, posters, moderated sessions, etc.:
- US Fusion Guided Prostate Biopsy: Integrating MP MRI and Biopsy into Your Urologic Practice for Screening, Diagnosis and Treatment Planning
Dr. Patrick Selph presentations, posters, moderated sessions, etc.:
- Conservative and Endoscopic Management of Urethral Trauma
Dr. Tracey Wilson presentations, posters, moderated sessions, etc.:
- Take Home Messages: Female Urology/Incontinence
Dr. Kyle Wood presentations, posters, moderated sessions, etc.:
- RNA interference of Hepatic Lactate Dehydrogenase Reduces Urinary Oxalate in a Mouse Model of Primary Hyperoxaluria Type 1
- Association of Obesity with Increased Endogenous Oxalate Synthesis
- Urinary Oxalate Excretion in Obese Mouse Model
Dr. Luke Ellenburg (PGY-3) posters, moderated sessions, etc.:
- The Use of Formalin as a Fixative for Testicular Biopsies
Carter Boyd (3rd year UAB MD/MBA student) posters, moderated sessions, etc.:
- Screening for Primary Hyperparathyroidism in a Tertiary Stone Clinic, a Useful Endeavor
- An Intervention to Increase 24-hour Urine Collection Compliance
- **Carter Boyd was also awarded the Urology Care Foundation Summer Medical Student Fellowship for “Endogenous Oxalate Synthesis in a Diet-Induced Obese Mouse Model”**
Recap: 2018 Gulf Coast Urology Seminar
The UAB Department of Urology sponsored the 2018 Gulf Coast Urology Seminar in beautiful Destin, Fla., July 13-15. The thought-provoking program made for a weekend of quality urologic education, networking with colleagues and enjoying one of the most beautiful beaches in the country.
Attendees had the opportunity to take part in many programs and sessions.
To kick off the weekend, the Men’s Health and Prosthetic Surgery session was moderated by Dr. Patrick Selph. UAB Urology faculty topics in this session included:
- "Modern Management of Peyronie’s Disease" by Dr. Patrick Selph
- "Supplements and Male Infertility" by Dr. Peter Kolettis
After a quick Q&A and case presentations, Dr. Sunil Sudarshan moderated the first oncology session which included presentations by several UAB Urology faculty.
- "Bladder Preservation for High Grade Bladder Cancer" by Dr. Jeffrey Nix
- "Prostate Cancer Screening: Update by the US Preventive Services Task Force" by Dr. Sunil Sudarshan
- "Fluciclovine F18 and PSMA PET Imaging for Prostate Cancer" by Dr. Soroush Rais-Bahrami
The first day concluded with a networking reception that included attendees, spouses and guests.
Saturday began with a session on Endourology/Nephrolithiasis moderated by Dr. John Burns. UAB Urology faculty presentations included:
- Dr. Kyle Wood on "Missed Diagnoses in the Management of Kidney Stone Disease and Management of the Encrusted Ureteral Stent"
- Dr. Dean Assimos on "Complications of PCNL"
The next session was moderated by Dr. Patrick Selph and focused on Health Policy. Dr. Patrick Selph also presented “Experience with Urology in Europe: The EAU-AUA Scholar Exchange Program” during this session.
On Saturday evening, attendees gathered for a nice dinner at the Marlin Grill in Baytowne Warf.
A second oncology session moderated by Dr. Patrick Selph kicked off the final day of the conference. Sessions by UAB Urology faculty included:
- "Surgery for Oligometastatic Prostate Cancer" by Dr. Jeffrey Nix
- "Expanding Indications for Prostate Cancer Surveillance" by Dr. Soroush Rais-Bahrami
The day ended with a session on Andrology and Pediatric Urology moderated by Dr. Patrick Selph with presentations by:
- Dr. Peter Kolettis giving an "Update on Vasectomy"
- Dr. Pankaj Dangle on "The Use of Robotic-Assisted Surgery in Pediatric Urology"
Alumni Spotlight: Dr. Win Shun Lai
Where are you headed now that you've graduated?
General urology position with Baylor, Scott and White in Austin, Texas.
What are your clinical and research interests?
Robotics and reconstruction.
How did you choose to practice this area of urology?
In terms of robotics, by the end of residency I felt the most comfortable and confident on the console of the robot compared to open procedures; I really am fascinated by how technology has changed urology and look forward to participating in its advancement of the field. Reconstruction was the area of urology that most interested me during residency.
What aspect of your time at UAB do you believe was most valuable as you started your career?
The number and diversity of the cases that I participated in definitely gives me confidence in terms of starting out. UAB urology has all the sub-specialties covered, which, in addition to a large volume of trauma and emergent cases while on call, I feel has prepared me well for what lies ahead.
Did you have a particular mentor while at UAB? If so, why were they a good mentor?
Research wise I worked with Dr. Rais Bahrami and Dr. Assimos. They both have tremendous enthusiasm for research and numerous novel ideas; their guidance allowed projects to easily turn into publications in reputable journals.
Surgically I really admired Dr. Sudarshan and Dr. Nix. They were both excellent surgeons and technically proficient. Both gave an appropriate balance of independence and instruction in the OR, which ultimately is what allowed me to develop confidence in my surgical skills.
What is one of your fondest memories from UAB?
The graduation ceremony was a great way to end residency. It gave me an opportunity to thank my family, the faculty and co-residents for everything they’ve done to get me to this point. Other than that, the daily interactions with my co-residents and the inside jokes and bonds we developed over the years will stick with me the most.
Give one piece of advice for current residents.
When you do well, praise each other; when you fail, support each other; in time you’ll come to respect and love each other.
What do you like to do in your free time?
Currently, lounging by the highest pool in the state of Texas, reuniting with old friends and playing with my dog. Also I started painting portraits of clowns.
Wood Receives NIH K08 Grant
Assistant Professor Dr. Kyle Wood was recently awarded a K08 grant by the National Institutes of Health (NIH).
The K08 grant is a 5 year NIH mentored clinical scientist research career development award titled “Obesity ad Endogenous Oxalate Synthesis”. There has been increasing prevalence in both kidney stone disease and obesity throughout the United States, especially in the Southeast, and this grant will evaluate the role of oxalate, a main component of the most common type of kidney stone.
The Department of Urology's Kidney Stone Research Laboratory has demonstrated that with increasing BMI, there is an increase in the body’s creation of oxalate. Understanding these associations and mechanisms may lead to future therapies.
Dr. Wood's mentors and collaborators include Barbara Gower, PhD; Ross Holmes, PhD; Dean Assimos, MD; Jennifer Pollock, PhD; Robinna Lorenz, MD, PhD; Sunil Sudarshan, MD; and John Knight, PhD. All are distinguished faculty at UAB.
My Experience: Urology in Europe
Dr. Patrick Selph was chosen to be a part of this year’s American Urological Association (AUA) and European Association of Urology’s (EAU) Academic Exchange Program. The program is designed to provide young urology faculty with an international perspective on urologic medicine and allows the sharing of knowledge and experience between the AUA and EAU. Dr. Selph spent 18 days visiting European institutions and attended the EAU annual meeting in Copenhagen, Denmark.
Dr. Selph writes about his experience:
"The trip began in Sheffield, England where I met with Christopher Chapple, the secretary general of the EAU. There, I learned about the nuances of the NHS in England, including how the government system has allowed them to perform many randomized trials on MRI and treatments for prostate cancer. Treatment for patients in NHS have a benign problem and can be many months from the time of diagnosis, but a private healthcare system exists that gives patients the opportunity to get surgeries done quicker but at a cost. I also observed multiple surgeries in England including robotic prostatectomy (they only have the S I robot) and a prone urethral diverticulectomy.
After visiting England, I moved on to Milan, Italy where I spent time with Dr. Francesco Montorsi at San Raffaele Hospital. While Italy also has a nationalized healthcare system, San Raffaele hospital is purely private. Patients come here for surgery and they pay out-of-pocket for cost. The surgeons were very technically gifted, but for lower rate prostate cancer’s you may have to wait one year for surgery.
The next stop on the trip was Nijmegen, The Netherlands. Their healthcare system is nationalized and there is no private insurance whatsoever. Again, this afforded accessibility for patients but benign surgical conditions would usually be operated on in 4 to 6 months. Radboud University Medical Center is also the site of some of the original prostate MRI development, and is a leader in the creation of the PIRADS system. Here, patients had shared rooms with and they often sit at tables talking to each other. While in the U.S. everyone seems to demand a private room, in Europe the patients seemed happy to talk/commiserate with each other during their admissions. Perhaps we will see something similar soon in the U.S.!
The final stop was at University in Copenhagen, Denmark which has the largest urology department in Europe with 95 urologists. They have two separate hospitals, one of which does benign surgery and the other that does cancer surgery. This allowed patients to get their operations sooner than they otherwise would. They largely did all their oncology cases robotically including over 450 intracorporeal urinary diversions.
Overall, it was a great experience to learn the differences between healthcare systems. They were certainly fascinated by the talks I gave on GU trauma (gunshot wounds don’t happen often in Europe!) and the discussion surrounding obesity and how it affects the way we do surgery here versus in Europe. I was able to make some lasting friendships with urologists from the U.S. with whom I traveled as well as relationships with the European centers. I’d highly encourage going to the EAU at least once in your career to see how differently Europeans sometimes think about the same conditions we treat here in the U.S. Last but not least, I’d like to thank Dr. Assimos for letting me travel for almost a month to be able to have this experience!"
UAB Urology Match 2018
The Department of Urology is excited to welcome our new residents to UAB! We have three new PGY-1 residents joining the team, and are also excited to add two new PGY-2 residents this summer. Meet the team:
Andrew Fang attended McGovern Medical School at the University of Texas at Houston. He’ll be joining UAB Urology as a PGY-1 this summer.
Joseph Fougerousse comes to UAB as a PGY-1 from Louisiana State University School of Medicine New Orleans.
Jennifer Rosen completed medical school at the University of Tennessee Health Science Center and will be joining UAB Urology as a PGY-1.
Robin Iriele will be joining UAB Urology as a PGY-2. After completing medical school at Case Western Reserve School of Medicine, she completed an internship at University Hospital in Cleveland Medical Center.
Michael Kongnyuy attended the University of South Florida Morsani College of Medicine for medical school. After completing his internship at New York Presbyterian in Queens, NY., he will join UAB Urology as a PGY-2.
Six UAB Urology Physicians Named to Best Doctors in America® List
Congratulations to Dr. Dean Assimos, Dr. James Bryant, Dr. David Joseph, Dr. Peter Kolettis, Dr. Keith Lloyd and Dr. Jeffrey Nix.
Best Doctors in America recognized UAB doctors from 39 specialties and 179 subspecialties, with the total number of national physicians included reflecting only 4 percent of doctors in America. The only way for a physician to be selected is to be peer-nominated and voted in by current Best Doctors winners.
Best Doctors is a global benefits provider and medical information services company that connects individuals facing difficult medical treatment decisions with the best doctors, selected by impartial peer review in more than 450 subspecialties of medicine, to review their diagnosis and treatment plans. Best Doctors prides itself on having more than 40 million members worldwide.
For more information, please visit BestDoctors.com.
Kidney Stone Research Lab Update
The UAB Department of Urology continues to be a leader in kidney stone research. As the department continues to expand its clinical and translational research, we hope you’ll check back often for updates.
Read moreAlumni Spotlight: Dr. Courtney Shepard
I graduated in 2015.
Where are you now?
Ann Arbor, Michigan
What made you decide to be a urologist?
My grandfather battled with prostate cancer for 20 years before succumbing to it right before I started medical school. After that, I initially intended to go into urologic oncology to help men and families facing a similar diagnosis. But during residency, I found myself drawn to the pediatric population, and in particular those patients with physical disabilities such as spina bifida. My mom is a physical therapist with a passion for helping patients with physical disabilities and growing up I spent a lot of time in her office. I didn’t realize the impact that had on me until I got to residency.
What is your current practice and how did you choose to practice this area of urology?
I am currently completing my third year of a combined pediatric urology and health services research fellowship at the University of Michigan. My research is focused on transitions of care for patients with spina bifida and I am also working to create a transitional care clinic here (but we have a long way to go to catch up with UAB’s spina bifida clinic!). I am particularly passionate about helping these patients get the sexual and reproductive health care and education they need.
What aspect of your time at UAB do you believe was most valuable as you started your career?
UAB gets some of the craziest and most extreme pathology, which has been immensely helpful when I think about how I will evaluate and treat a patient with an unusual presentation or advanced disease. So far I haven’t seen anything I hadn’t seen before in residency.
Did you have a particular mentor while at UAB? If so, why were they a good mentor?
During every case, at some point I always tell the resident, “when I was resident, I had an attending who…” I’ve truly learned so much from each attending and have incorporated what they do into my own practice. I am so grateful to all of the faculty for all they taught me. I am sure Dr. Joseph thought he’d be done with me when I moved to the great white north, but I still call and email him for advice. He patiently taught me operative skills, encouraged me both clinically and in research, gave thoughtful advice and feedback, always made time to meet (which he still does), and was always ready with a witty comment at just the right time. He also taught me that much of the healing we can do as physicians comes not from what we do in the OR, but from how we care for patients and families through our words and interactions.
Give one piece of advice for current residents.
Drink lots of O’Henrys coffee. Eat as much Saws as possible. And salted chocolate chip cookies from Woodlawn Cycle. Walk outside between the OR and floor when you can—the sunshine helps. Make time to hang out with your coresidents and be there for them. And keep a journal. Draw out and write down the steps of every surgery with the different attendings. Remember the details. Write down new observations you make each time. Write down what you learn from intra-op and post-op complications. Write down new things you learn during conferences. One of my high school teachers used to always say “you are responsible for your own education.” I used to think that was bogus, but it couldn’t be more true. These 5 years are so hard and can seem so very long, but I promise they will end. And the details of procedures you used to do all the time will become hazy very quickly. This is the only time you have when so many experts are focused on teaching you all aspects of urology—you will need that knowledge at some point, so make the most of your time now.
What do you like to do in your free time?
My husband and I love to explore—backpacking, kayaking, traveling, generally trying anything new, and brining our dog along whenever possible. I also love to run, but with the way this winter is going, I may have to take up cross-country skiing instead.
A Movember Celebration
Participants enjoyed a night of food, drinks, networking and raffle prizes while discussing how UAB could make a difference in the way health services reach and support men.
The two departments also joined to create a fundraising team, UAB-Movember, with the Movember Foundation, the only multinational charity that aims to raise awareness and funds for research into men’s health issues. The team raised more than $1,000.
If you wish to get involved, it’s not too late! Please consider making a donation to team UAB-Movember by November 30th. Any amount will help change the face of men’s health.
UAB Urology: A Leader in Kidney Stone Research
Tanecia Mitchell, Ph.D. and Sonia Fargue, Ph.D. have received NIH K01 grants, and John Knight. Ph.D. received a RO1 grant in the last year. Kyle Wood. M.D. was added as faculty last year and has research grants from the American Urological Association, Rare Kidney Stone Consortium and intramural grants from the Nutrition and Obesity Research Center.
John Knight, Ph.D., was recently the senior author of an article February 2017 in Journal of the American Society of Nephrology titled An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria. This article lead Alnylam Pharmaceuticals to begin clinical trials using this target in the treatment of patients with primary hyperoxaluria. This partnership has led to the investigation of other targets, with Kyle Wood, M.D., as the project leader, that could be used to treat kidney stone disease.
Recently, the group presented on the effects in mice of targeting lactate dehydrogenase in the liver using RNA interference. They demonstrated a more than 75 percent decrease in urinary oxalate excretion in a mouse model of primary hyperoxaluria type I, which represents a complete correction of the hereditary abnormality. Primary Hyperoxaluria is a rare genetic disease that results in recurrent kidney stones and ultimately end-stage renal disease. Currently, the only reliable treatment is a kidney/liver transplant.
Billy Tingle, BSRN recently joined the group and has focused on patient recruitment for studies focusing on the role of the microbiome and obesity in kidney stone disease. Studies are ongoing to determine if subjects can be colonized with Oxalobacter formigenes, a bacterium that is capable of degrading oxalate in the gastrointestinal tract. Colonization with this may reduce kidney stone disease.
Overview: Gulf Coast Urology Seminar 2017
2017 American Urological Association Annual Meeting
UAB Urology held multiple activities and presentations this year. Dr. Soroush Rais-Bahrami was a faculty for the Hands-on MRI/US fusion biopsy course where he lent his expertise on the technology to guide urologists implementing this platform in their practice. Along with PGY-5 Dr. Win Shun Lai, he also presented data on renal cell carcinoma (RCC) in young patients. A review of the last five years at UAB found that 98/604 patients with RCC were less than age 46 years. The good news for these patients was that early onset RCC tended to be lower grade and organ confined, though more patients underwent radical nephrectomy as opposed to nephron-sparing surgery. The latter finding suggests that perhaps these patients are being over treated for their disease.
Dr. Lai and Dr. Dean Assimos presented a systematic review and meta-analysis on factors associated with post-operative infection after percutaneous nephrolithotomy. They found that preoperative urine culture, intraoperative renal pelvis culture, stone culture, the number of access points, the need for blood transfusion, stone size and duration of procedure were significantly associated with post-operative infection.
From Dr. Tanecia Mitchell’s lab, PGY-4 Dr. Vidu Yarlagadda presented a study on the effect of calcium oxalate crystals on mitochondrial dysfunction in monocytes. Their study found that in human monocyte cell lines, exposure to calcium oxalate crystals caused a dose-dependent decrease in mitochondrial function and cell viability. The result was upregulation of stress response proteins, which may have implications for cellular dysfunction in calcium oxalate stone formers. Dr. Yarlagadda also presented Dr. Patrick Selph's experience with the robotic-assisted use of the appendix as a ureteral interposition for ureteral stricture disease. The case was a 32-year-old gentleman with a 5 cm. proximal ureteral stricture, and the robot was used to interpose the appendix between the proximal and distal ureter. At 10 months after surgery, the patient is pain free and has no hydronephrosis.
Dr. Kyle Wood presented his work on increased urinary excretion of glycolate and oxalate in obese and diabetic mice models, as well as the association of hemoglobin A1c and urinary oxalate in stone formers. A review and video of his work can be found here.
Dr. Peter Kolettis moderated a poster session on infertility therapy, and Dr. Selph was a faculty mentor in a speed mentoring session for urology residents interested in questions about career, work-life balance, leadership and research.
Last but not least, UAB Urology had its first annual alumni banquet at the AUA. Faculty members were excited to see Dr. Katherine Cameron, a 2007 graduate of the program, who works in Knoxville, TN., stomping out urologic disease. Faculty also caught up with Dr. Corey Passman, another 2007 graduate, who is enjoying his practice in Lynchburg, VA. Courtney Shepard, a recent graduate of UAB in 2015, loves her experience at the University of Michigan Department of Urology where she is finishing up her pediatric fellowship. Dr. James Lingeman from Indiana University graced was also in attendance, and it was fascinating to hear his experience with HoLEP and the early days of shockwave lithotripsy.
- Joseph Receives Reginald C. Bruskewitz Distinguished Alumni Award
- UAB Urology ranked #20 in U.S. News Best Hospitals
- Hundreds of UAB physicians named to prestigious 2015-16 Best Doctors in America list
- Dangle establishes a pediatric robotic urologic surgery program at Children's
- Alumni Spotlight: Ben Martin, M.D.
- Successful Interview Season Complete
- UAB Surgical Team Proud of Outcomes From ERAS Pathway
- Resident shares research experience
- Mitchell receives K01 Award from NIH
- UAB and Baptist Health partner to open new clinic in Montgomery
- 2015-2016 Update and Doximity Voting
- Welcome New Faculty: Drs. Dangle and Wood
- Kidney Stone Group Clinic Now Accepting Referrals
- SESAUA Update 2016
- Outgoing and Incoming Residents 2016
- Nix Named Director of Robotic Surgery
- Dr. Killian shares her training experience in Zambia
- Assimos gives two talks at AUA