The Department of Urology at UAB is actively involved in both clinical, basic science and translational research endeavors. We have a large tissue and biologic fluids library of hundreds of urologic cancer specimens for internal study. This is a basis for which we are attempting to identify markers and characteristics to stratify patients into risk groups. We are also investigating renal ischemia in an animal model to identify means of optimizing renal function and markers that predict outcomes.  Our residents spend 6 month blocks performing both clinical and basic science research during their tenure at UAB.

The Department of Urology participates in multiple clinical trials. We are members of the Eastern Cooperative Oncology Group and Early Detection Research Network (branch of the National Cancer Institute), actively involved in multi-institutional studies in urologic cancer. Our translational involvement in chemoprevention studies of bladder and prostate cancer is part of the chemoprevention consortium of our NCI Comprehensive Cancer Center. We participate in numerous non-cancer studies including investigating the feasibility of tissue engineering and the role of bladder replacement in both pediatric and neuro-urology patient populations.

The DIGNITY2 study is a global medical research study of a new investigational dosage of an approved medication for people with bladder problems as a result of MS. The study is testing to see whether this new dose is also effective at reducing urinary leakage, and to evaluate the side effects related to this new dose.