Jeff Hansen
| This email address is being protected from spambots. You need JavaScript enabled to view it.Research Editor
jeffhans@uab.edu • (205) 209-2355Communicates UAB research discoveries and initiatives from across the university for a variety of audiences.
Specific beats include: biochemistry; cell, developmental and integrated biology; microbiology; molecular genetics; neurobiology; pathology; pharmacology and tocixology; Alabama Drug Discovery Alliance; Bill L. Harbert Institute for Innovation and Entrepreneurship.
The site-directed addition of a polymer on the antibody trastuzumab helped this cancer-fighting antibody cross the blood-brain barrier.
These immune CD8 T cells may provide a target for treating the buildup of fatty lesions in the arteries called atherosclerosis.
Vaccination of neonatal mice with group A Streptococcus promotes clonal expansion of B cells that produce antibody against GlcNAc. The association of reduced Type 1 diabetes risk after group A Streptococcus infection is dependent on these GlcNAc-specific B cells.
Tuberculosis, the world’s leading infectious disease killer, caused 1.6 million deaths in 2021, along with 10 million new cases of tuberculosis every year.
Vascular stiffening and calcification, which is accelerated by aging, affects multiple organs and plays a role in dementia. There are no treatments for vascular calcification, which makes arteries harden.
The model may provide novel insights into RP59 disease mechanism that will guide future testing of therapeutic interventions.
Researchers have identified a gut-lung axis driven by intestinal antimicrobial peptide expression and mediated by the intestinal microbiota that is linked to lung injury in newborns.
Researchers found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment. Most transplant failures occur in the first four weeks.
Analysis of a survey of 18,041 people in rural KwaZulu-Natal revealed a discrepancy between the ability of the South African health system to respond to the health needs of people with communicable diseases and the health needs of people with non-communicable diseases.
Lung-resident memory B cells produced during influenza are long-living immune cells that migrate to the lungs from draining lymph nodes and lie in wait as early responders that can quickly react to future infections. They are key sentinels against subsequent viral variants.