L251601
Mentor: Dr. Corinne Augelli-Szafran, Department of Biochemistry and Molecular Genetics
General Summary:
This is a 2-year appointment that serves as a research trainee for the purpose of enhancing and developing research and drug development competencies. In this appointment, the postdoctoral researcher will be responsible for providing synthetic chemistry support for small molecule drug discovery and medicinal chemistry optimization. The researcher will participate in designing and conducting highly technical synthetic chemical operations under the supervision of a senior scientist and will analyze research data, provide interpretations, contribute to the development of research documentation for publications and provide technical reports and records.
Key Responsibilities:
- Synthesizes, purifies, and fully characterizes compounds for the assigned projects
- Participates in designing and conducting highly technical and complex research projects under the direction of a supervisor
- Develops structure-activity relationships under the direction of a supervisor
- Maintains E-notebooks in real time with detailed and accurate procedures and complete analytical data attached
- Identifies, compiles and evaluates data sources, background information and technology related to the area of specialization; some examples would be searching SciFinder for synthetic routes and commercially available compounds
- Prepares weekly updates for weekly meetings with PI/Supervisor
- Prepares updates for project team meetings for assigned projects
- Contributes to progress reports, patent applications and publications using available data from assigned projects
- Operates and maintains laboratory equipment
- Maintains external awareness of scientific discipline through familiarity of current scientific literature
- Orders chemicals and lab supplies; registers chemicals and updates the laboratory inventory spreadsheet and the EHS chemical inventory
- Processes and registers synthesized analogs as well as prepare and ship/deliver samples for testing
- Implements and observes appropriate safety requirements following Standard Operating Procedures (SOP)
Requirements/Minimum Qualifications:
- D. in Organic or Medicinal Chemistry
- Visa sponsorship (now or in the future) is not available for this position; applicants must be legally authorized to work in the United States
- Strong synthetic organic chemistry background required
- Keen interest in understanding the application of medicinal chemistry principles
- Research experience in this field of specialization with advanced knowledge of equipment, procedures, and methods of analysis
- Ability to observe appropriate safety requirements
- Competency in ChemDraw, MestReNova, SciFinder, Microsoft Office Suite products and other relevant software
- Good communication and writing skills
- Demonstrated ability to work in a collaborative team environment
To apply:
Send your CV to Dr. Corinne Augelli-Szafran at
About our Postdoc Office
UAB is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 300 postdoctoral fellows are training currently in a variety of disciplines. Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The Office of Postdoctoral Education strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.
About the University
The University of Alabama at Birmingham (UAB) is a research university and academic health center that discovers, teaches, and applies knowledge for the intellectual, cultural, social, and economic benefit of Birmingham, the state, and beyond. UAB is internationally renowned for its intensely collaborative culture that has — for more than five decades — produced breakthroughs in education, health care, research, and service. UAB was ranked #1 in the United States, and in the top 10 worldwide, in the Times Higher Education World University Rankings, 2018 Young University Rankings.
Spanning more than 100 city blocks, UAB is the state of Alabama’s largest single employer with nearly 28,000 employees and has an annual, state-wide economic impact of $12.1 billion. U.S. News & World Report’s 2022 “America’s Best Graduate Schools” ranks 16 UAB graduate programs among the nation’s top 25 and eight UAB specialties were ranked among the nation’s top 50 in the magazine’s 2022-2023 Best Hospitals report. UAB research grants and awards are at a record high, totaling $715 million in FY22 — a 50% increase over the past five years. UAB ranks 33rd among all universities in federal research funding and 17th among public universities. UAB's NIH funding continues to grow among peer institutions in the Southeast and beyond, with the university ranking 25th among all universities in NIH funding and 11th among public universities.
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