Cryo-Electron Microscopy Core Facility

Research Administration Centers and Cores Cryo-Electron Microscopy Core Facility

Cryo-Electron Microscopy Core Facility

Directory Category: Core

The UAB cryo-EM core facility offers advanced electron microscopy (EM) services to the UAB community and to external academic and commercial users. Services offered include high resolution EM of negatively stained or cryogenically frozen samples, electron tomography, cryo-sectioning and immunocytochemistry on cryo-sections (Tokuyasu technique). The facility is equipped with an FEI Tecnai F20 FEG microscope and is located in the basement of Shelby Biomedical Research Building (SHEL B40). An FEI Vitrobot, a Leica cryo-ultramicrotome, lab space for sample preparation and a dark room for film processing are  available. The cryo-EM core facility is available for use by trained users (training is available and encouraged), or as a service carried out by a trained technician. Usage and services are offered at reasonable hourly rates to recover costs associated with the operation of the facility