Karan P. Singh, PhD

singhProfessor, Division of Preventive Medicine
Director, UAB CCC’s Biostatistics and Bioinformatics Shared Facility (BBSF)

Contact Information:

Medical Towers 647
1717 11th Avenue South
Birmingham, Alabama 35205
Phone: (205) 934-6887
Fax: (205) 934-4262
This email address is being protected from spambots. You need JavaScript enabled to view it.

Research Interests

Chronic disease modeling, clinical trials design and survival methodology, health services methodological research, longitudinal data analysis, multistate cancer modeling, and statistical computing

Educational Background

  • University of Memphis, TN, PhD, 1986, Statistics
  • Old Dominion University, VA, MS, 1983, Applied & Computational  Mathematics
  • CCSHA University, India, M.Sc., 1977, Statistics
  • Meerut University, India, B.Sc., 1975, Chemistry, Mathematics, Physics

Professional Activities

Member or Chair-Scientific Review Panels
  • 1994-Present, NIH Special Emphasis Review Panels/Site Visits/ Reverse Site Visits
  • 1998-Present, Congressionally Directed Medical Research Programs (CDMRP)-DOD Review Panels
  • 1998-Present, National Institute on Disability and Rehabilitation Research (NIDRR) Study Review Panels
  • 2001-Present, AHRQ Special Emphasis Review Panels
  • 2002-Present, Susan G. Komen for the Cure Cancer Scientific Review Panels
  • 2005-Present, Oklahoma Health Research Program Scientific Review Panels
  • 2007-Present, HRSA Special Emphasis Review Panels
  • 2013-Present, PCORI Review Panels
Data and Safety Monitoring Board (DSMB)
  • 2006-08, Chairman-DSMB, NIH-NCCAM Randomized Controlled Trial of Osteopathic Manipulative Treatment (OMT) and Ultrasound physical Therapy for Chronic low back pain, UNTHSC TCOM
  • 2009-12, Member, NIH-NCCAM Randomized Controlled Trial of Osteopathic Manipulative Treatment (OMT) and Ultrasound physical Therapy for Chronic low back pain, UNTHSC TCOM
  • 2010-Present, Member-DSMB, NIH Randomized Trial of Physical Activity Self-management Intervention for Patients with COPD, University of Texas Health Science Center at Tyler.
Organizer, Chair-Scientific Sessions in Conferences/Congresses
  • Co-organizer: Scientific Sessions on Modeling Data in Health Sciences, International Congress on Modeling and Simulation, Perth, Australia, December 1-6, 2013
  • Chair: Scientific Session on Cancer Genetics, Epidemiology, Biostatistics and Prevention, World Cancer Congress, Xi’an, China, May 23-25, 2013
  • Chair: Scientific Session on Public Health Nutrition, International Conference on Nutritional Science and Therapy, Philadelphia, July 15-17, 2013
  • Chair: Scientific Session on Epidemiology and Genetic Epidemiology, 31st Annual Conference of the Indian Society for Medical Statistics, Christian Medical College, Vellore, Tamilnadu, India, October 24-26, 2013 
  • Chair: Scientific Session on Mitochondrial Disorders: Diagnostics and Clinical Implications, 2nd Annual Conference of the Society for Mitochondrial and Medicine-India (SMRM): Mitochondrial in Health and Diseases, Ahmedabad, India, November 2-3, 2012
  • Chair: Scientific Session on Mathematical Methods in Systems Biology and Population Dynamics, Cape Town, South Africa, January 4-7, 2012
  • Chair: Plenary Session, International Conference on Mathematics of Date, Allahabad, India, December 31, 2010, to January 5, 2011. Co-organizer and Co-Chair: Scientific Sessions on Statistical Modeling in Health and Biomedical Sciences, International Congress on Modeling and Simulation, Cairns, Australia, July 13-17, 2009
  • Co-Organizer and Co-Chair: Scientific Sessions on Statistical Methods for Analysis of Public Health Data, International Congress on Modeling and Simulation, University of Canterbury, Christchurch, New Zealand, December 10-13, 2007
  • Organizer and Chair: Microarray Data Analysis-Statistical Problems, Joint Research Conference in Statistics, Knoxville, June 7-9, 2006
  • Organizer and Chair: Applications of Fuzzy and Informatics in Environmental and safety, 9th Word Multi-      Conference on Systemics, Cybernetics and Informatics, Orlando, June 11-13, 2005
  • Organizer and Chair: Statistical Modeling in Health and Biomedical Sciences, International Congress on Modeling and Simulation, Townsville, Australia, July 14-17, 2003
  • Chair: Biostatistics, International Conference on Statistics, Honolulu, Hawaii, June 5-9, 2002
  • Organizer and Chair: Statistical Modeling in Health and Medical Sciences, International Congress on Modeling and Simulation, Canberra, Australia, December 2001
  • Organizer and Chair: Advances in Biostatistics-International Conference in Statistics, Combinatorics and Related Areas, Mobile, AL, December 1999
  • Organizer and Chair: Medical and Public Health Research -International Congress on Modeling and Simulation, Hamilton, New Zealand, December 1999
  • Organizer and Chair: Advances in Biostatistics-International Conference on Combinatorics, Statistics, Pattern Recognition and Related Areas, Mysore, India, December 1998
  • Organizer and Chair: Epidemiology, Health and Medical Research, Hobart, International Congress on Modeling and Simulation, Tasmania, Australia, December 1997
  • Chair: Statistical Modeling for Environmental Data, International Congress on Modeling and Simulation, Newcastle, Australia, November 27-30, 1995
  • Organizer and Chair: Health Effect/Health Assessment and Life Style Models-International Biometric Society-ENAR, Spring Meeting, Birmingham, AL, March 1995
  • Organizer and Chair: Health Effects Assessment, The International Environmetrics Society Conference, The International Environmetrics Society Conference, Burlington, Ontario, Canada, August 1994
  • Chair: Characterization of Distances with Application Session - Quality Improvement Methods for Correlated Data Session, ASA, Winter Conference, Atlanta, GA, August 1994
  • Organizer and Chair: Risk Assessment, The International Environmetrics Society Conference, Helsinki, Finland, August 1992
  • Chair: Mathematical Statistics Session-Third Canadian Conference in Applied Statistics, Montreal, Canada, August 1991.
  • Organizer and Chair: Risk Analysis, The International Environmetrics Society Conference,  Como, Italy, September 1990
Editorial Boards of Journals
  • Editor, Molecular Cancer Biology, 2012-Present
  • Associate Editor, Universal Journal of Mathematics and Mathematical Sciences, 2011-Present
  • Editorial Board,  Advances and Applications in Statistics, 2011-Present
  • Editorial Board, Statistics Research Letters, 2013-Present
  • Editorial Board, International Journal of Food Safety, Nutrition and Public Health, 2010-Present
  • Editorial Board, Topics in Integrative Health Care: An International Journal, 2010-Present
  • Associate Editor, European Journal of Pure and Applied Mathematics, 2007-Present.
  • Editorial Board, Far East Journal of Mathematics, 2006-2012
  • Editorial Board, Journal of Modern Applied Statistical Methods, 2002-2010
  • Associate Editor-Environmetrics, 1992-1997
Reviewer of Scientific Journals, Including
  • American Journal of Cardiology, American Journal of Physiology, American Journal of Public Health, American Journal of Radiology, Annals of Surgical Oncology, Arthritis Care and Research, Biometrics, Communications in Statistics, Journal of American Medical Association, Journal of Applied Statistics, Journal of Computer Science & Computational Mathematics, Journal of Comparative Neurology, Journal of Computational Statistics and Data Analysis, Journal of General Internal Medicine, Journal of School Health, Journal of Statistical, Computation and Simulation, Journal of Statistical Planning and Inference, Journal of Theoretical Biology, Maternal and Child Health Journal, Medical Care, Neurobiology of Aging, Risk Analysis, Statistics in Medicine, Statistical Modeling, Statistica Neerlandica, and Statistica Sinica.
External Reviewer- Faculty: Promotion, Tenure, Honors and Awards
  • Feinberg School of Medicine, Northwestern University
  • Wright State University School of Medicine
  • Department of Biostatistics, Colleges of Medicine and Public Health, University of Arkansas for Medical Sciences
  • University of Texas Medical Branch School of Medicine
  • Department of Epidemiology and Biostatistics, Texas A&M Health Science Center School of Rural Public Health
  • Department of Epidemiology and Biostatistics, University of Oklahoma Health Science Center
  • Department of Biostatistics, Tulane University
  • Department of Mathematical Sciences, University of Texas at Dallas
  • Department of Mathematics, Central Michigan University
  • Department of Statistics, King Saud University, Saudi Arabia
  • Department of Statistics, UAE University, United Arab Emirates

Professional Societies
  • American Society of Clinical Oncology
  • American Statistical Association
  • International Statistical Institute (ISI)
  • International Biometric Society-ENAR
  • The International Environmetrics Society (TIES)
  • Modeling and Simulation Society of Australia and New Zealand (MSSANZ)
  • American Public Health Association (APHA)
  • Academy Health
  • National Environmental Health Association
  • Institute for Diversity in Health Management

Selected Recent Publications

  • Zhang B, Zhang B, Chen X, Bae S, Singh KP, Washington MK, Datta P: Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway. British Journal of Cancer 2014 Jan 2, doi: 10.1038/bjc.2013.789. [Epub ahead of print]. [PMID: 24384683].
  • Licciardone JC, Minotti DE, Gatchel RJ, Kearns CM, Singh KP: Osteopathic Manual Treatment and Ultrasound Therapy for Chronic Low Back Pain: A Randomized Controlled Trial. Annals of Family Medicine 2013 Mar; 11(2): 122-129. doi:10.1370/afm.1468. [PMID: 23508598. PMCID: PMC3601389].
  • Bovell LC, Shanmugam C, Putcha BD, Katkoori VR, Zhang B, Bae S, Singh KP, Grizzle WE, Manne U: The Prognostic Value of microRNAs Varies with Patient Race/Ethnicity and Stage of Colorectal Cancer. Clinical Cancer Research 2013 May 29. [Epub ahead of print]. [PMID: 23719259].
  • Kim KH, Dmitriev IP, Saddekni S, Kashentseva EA, Harris RD, Aurigemma R, Bae S, Singh KP, Siegal GP,  Curiel DT, Alvarez RD: A phase I clinical trial of Ad5/3-Δ24, a novel serotype-chimeric, infectivity-enhanced, conditionally-replicative adenovirus (CRAd), in patients with recurrent ovarian cancer.  Gynecologic Oncology 2013. Available online June 9, 2013. [Epub ahead of print]. [PMID: 23756180].
  • Tabatabai MA, Eby WM, Singh KP, Bae S: T model of growth and its application in systems of tumor-immune dynamics. Mathematical Biosciences and Engineering 2013 June; 10(3): 925-38. [PMID: 23906156].
  • Ojha RP, Jackson BE, Tota JE, Offutt-Powell TN, Singh KP, Bae S: Guillain-Barre syndrome following quadrivalent human papillomavirus vaccination among vaccine-eligible individuals in the United States. Human Vaccines and Immunotherapeutics 2013; 10(1). [Epub ahead of print]. PMID: 24013368.
  • Ashmore J, Russo R, Peoples J, Sloan J, Jackson BE, Bae S, Singh KP, Blair SN, Coultas D: Chronic Obstructive Pulmonary Disease Self-Management Activation Research Trial (COPD-SMART): Design and Methods.  Contemporary Clinical Trials. 2013 Jul; 35(2):77-86. [PMID:  23680985].
  • Jackson B, Suzuki S, Coultas D, Singh KP, Bae S: Rural-Urban disparities in quality of life among patients with COPD. Journal of Rural Health 2013. 2013 Aug; 29 Suppl 1:s62-9. DOI: 10.1111/jrh.12005. [PMID 23944281 PMCID:PMC3752695].
  • Ojha RP, Hanzis CA, Hunter ZR, Greenland S, Offutt-Powell TN, Manning RJ, Lewicki M, Brodsky PS, Ioakimidis L, Tripsas CK, Patterson CJ, Sheehy P, Singh KP. Treon SP: Family history of non-hematologic cancers among Waldenstrom macroglobulinemia patients: A preliminary study. Cancer Epidemiology 2012; 36: 294–297 [PMID: 22099500].
  • Wortz K, Cade A, Menard JR, Lurie S, Lykens K, Bae S, Jackson B, Su F, Singh KP, Coultas D:  A qualitative study of patients’ goals and expectations for self-management of COPD.  Prim Care Respiratory Journal 2012 Dec; 21(4):   384-91. [PMID: 23138844, PMCID: PMC3745027].

Awards, Honors and Recognitions

  • Member, Cervical Task Force (CTF) of the NCI Gynecologic Cancer Steering Committee (GCSC), December 2012-December 2016
  • Plenary Speaker, Mathematical Methods in Systems Biology and Population Dynamics, Cape Town, South Africa, January 4-7, 2012
  • Plenary Speaker, International Conference on Mathematics of Date, Allahabad, India, December 31, 2010-January 4, 2011
  • Outstanding Faculty in Research, UNTHSC School of Public Health at Fort Worth, 2010.
  • Academic Commendation of Excellence (ACE) Award, UNTHSC at Fort Worth, 2009
  • Outstanding Faculty Advisor, UNTHSC School of Public Health at Fort Worth, May 2008
  • Member-ASPH/Pfizer Public Health Academy of Distinguished Teachers
  • Fellow-Modeling and Simulation Society of Australia and New Zealand
  • Keynote Speaker, International Congress on Modeling and Simulation, Christchurch, NZ, December 10-13, 2007
  • Elected Member- International Statistical Institute (ISI)
  • Elected Member, DELTA OMEGA, the Honorary Public Health Society
  • Distinguished Paper Award, Business and Health Administration Association, 2008
  • Best Paper Award, Issues in Healthcare: Elderly, Hospice, and Home Care, Business and Health Administration Association, 2008
  • Distinguished Paper Award, Business and Health Administration Association, Business and Health Administration Association, 2007
  • MBAA International McGraw-Hill/Irwin Distinguished Paper award, 2007
  • Best Paper Award, Health Promotion and Prevention, Business and Health Administration Association, 2006
  • Best Paper-Occupational Exposure to Nitrous Oxide in Operating Room Nurses, Presented in the Session:
  • Applications of Fuzzy and informatics in Environmental and Safety Engineering Field, 9th World Multi Conference on Systematics, Cybernetics and Informatics, Orlando, FL, July 1-013, 2005
  • Outstanding Service Award-International Congress on Modeling and Simulation, Australia, 2001
  • Excellence in Mentoring and Advising: Alabama Minority Graduate Education Program, National Science Foundation, 2000
  • Distinguished Lecturer, Indian Institute for Medical Research, 1998, 2000
  • Distinguished Visiting Professor, University of Lampung, Indonesia, July 1999
  • VIP Award-Civitan International, 1993
  • Invited Participant in a NSF Sponsored Workshop on Statistical Methods in Molecular Biology, University of Berkeley, March 31-April 3, 1992
  • Guest Speaker:  Environmental Hazards Assessment Program, Medical University of South Carolina, March 5, 1993
  • Keynote Speaker: Annual Conference of Indian Society for Medical Statistics and National Seminar of Statistics in Maternal and Child Health, All India Institute for Medical Sciences, New Delhi, 1991
  • Invited Participant in a NSF Sponsored Workshop on Computational Molecular Biology, University of Washington, April 21-24, 1991
  • Invited Participant, the NSF Sponsored Workshop on Integrating Quality and Productivity Concepts in Statistics Courses, University of Knoxville, July 29-August 3, 1990
  • Outstanding Faculty in Research, Central Michigan University (CMU) Faculty Profiles, 1989-1990
    Outstanding Minority Student Mentor, CMU, 1989-1990
  • Research Professor Award, CMU, 1988-1989
  • Summer Research Fellow, CMU, 1988
  • Outstanding Teaching Assistant, Department of Mathematical Sciences, University of Memphis, 1985-1986
  • Summer Research Fellow, University of Memphis, 1986
  • Recipient of the Thomas L. Saaty Best Paper Award, American Journal of Mathematical and Management Science, 1982
  • Outstanding Communicator of Multi-cultures, International Speakers Bureau, Multicultural Center, ODU, 1982
Member or Chair-Scientific Review Panels
1994-Present, NIH Special Emphasis Review Panels/Site Visits/ Reverse Site Visits
1998-Present, DOD-Congressionally Directed Medical Research Programs (CDMRP) Review Panels
1998-Present, National Institute on Disability and Rehabilitation Research (NIDRR) Study Review Panels
2001-Present, AHRQ Special Emphasis Review Panels
2002-Present, Susan G. Komen for the Cure Cancer Scientific Review Panels
2005-Present, Oklahoma Health Research Program Scientific Review Panels
2007-Present, HRSA Special Emphasis Review Panels
2013-Present, PCORI Review Panels
Data and Safety Monitoring Board (DSMB)
2006-08, Chairman-DSMB, NIH-NCCAM Randomized Controlled Trial of Osteopathic Manipulative Treatment (OMT) and Ultrasound physical Therapy for Chronic low back pain, UNTHSC TCOM
2009-12, Member, NIH-NCCAM Randomized Controlled Trial of Osteopathic Manipulative Treatment (OMT) and Ultrasound physical Therapy for Chronic low back pain, UNTHSC TCOM
2010-Present, Member-DSMB, NIH Randomized Trial of Physical Activity Self-management Intervention for Patients with COPD, University of Texas Health Science Center at Tyler.
Organizer, Chair-Scientific Sessions in Conferences/Congresses
Co-organizer: Scientific Sessions on Modeling Data in Health Sciences, International Congress on Modeling and Simulation, Perth, Australia, December 1-6, 2013
Chair: Scientific Session on Cancer Genetics, Epidemiology, Biostatistics and Prevention, World Cancer Congress, Xi’an, China, May 23-25, 2013
Chair: Scientific Session on Public Health Nutrition, International Conference on Nutritional Science and Therapy, Philadelphia, July 15-17, 2013
Chair: Scientific Session on Epidemiology and Genetic Epidemiology, 31st Annual Conference of the Indian Society for Medical Statistics, Christian Medical College, Vellore, Tamilnadu, India, October 24-26, 2013  
Chair: Scientific Session on Mitochondrial Disorders: Diagnostics and Clinical Implications, 2nd Annual Conference of the Society for Mitochondrial and Medicine-India (SMRM): Mitochondrial in Health and Diseases, Ahmedabad, India, November 2-3, 2012
Chair: Scientific Session on Mathematical Methods in Systems Biology and Population Dynamics, Cape Town, South Africa, January 4-7, 2012
Chair: Plenary Session, International Conference on Mathematics of Date, Allahabad, India, December 31, 2010, to January 5, 2011. Co-organizer and Co-Chair: Scientific Sessions on Statistical Modeling in Health and Biomedical Sciences, International Congress on Modeling and Simulation, Cairns, Australia, July 13-17, 2009
Co-Organizer and Co-Chair: Scientific Sessions on Statistical Methods for Analysis of Public Health Data, International Congress on Modeling and Simulation, University of Canterbury, Christchurch, New Zealand, December 10-13, 2007
Organizer and Chair: Microarray Data Analysis-Statistical Problems, Joint Research Conference in Statistics, Knoxville, June 7-9, 2006
Organizer and Chair: Applications of Fuzzy and Informatics in Environmental and safety, 9th Word Multi-      Conference on Systemics, Cybernetics and Informatics, Orlando, June 11-13, 2005
Organizer and Chair: Statistical Modeling in Health and Biomedical Sciences, International Congress on Modeling and Simulation, Townsville, Australia, July 14-17, 2003
Chair: Biostatistics, International Conference on Statistics, Honolulu, Hawaii, June 5-9, 2002
Organizer and Chair: Statistical Modeling in Health and Medical Sciences, International Congress on Modeling and Simulation, Canberra, Australia, December 2001
Organizer and Chair: Advances in Biostatistics-International Conference in Statistics, Combinatorics and Related Areas, Mobile, AL, December 1999
Organizer and Chair: Medical and Public Health Research -International Congress on Modeling and Simulation, Hamilton, New Zealand, December 1999
Organizer and Chair: Advances in Biostatistics-International Conference on Combinatorics, Statistics, Pattern Recognition and Related Areas, Mysore, India, December 1998
Organizer and Chair: Epidemiology, Health and Medical Research, Hobart, International Congress on Modeling and Simulation, Tasmania, Australia, December 1997
Chair: Statistical Modeling for Environmental Data, International Congress on Modeling and Simulation, Newcastle, Australia, November 27-30, 1995
Organizer and Chair: Health Effect/Health Assessment and Life Style Models-International Biometric Society-ENAR, Spring Meeting, Birmingham, AL, March 1995
Organizer and Chair: Health Effects Assessment, The International Environmetrics Society Conference, The International Environmetrics Society Conference, Burlington, Ontario, Canada, August 1994
Chair: Characterization of Distances with Application Session - Quality Improvement Methods for Correlated Data Session, ASA, Winter Conference, Atlanta, GA, August 1994
Organizer and Chair: Risk Assessment, The International Environmetrics Society Conference, Helsinki, Finland, August 1992
Chair: Mathematical Statistics Session-Third Canadian Conference in Applied Statistics, Montreal, Canada, August 1991.
Organizer and Chair: Risk Analysis, The International Environmetrics Society Conference,  Como, Italy
     September 1990
Editorial Boards of Journals
Editor, Molecular Cancer Biology, 2012-Present
Associate Editor, Universal Journal of Mathematics and Mathematical Sciences, 2011-Present
Editorial Board,  Advances and Applications in Statistics, 2011-Present
Editorial Board, Statistics Research Letters, 2013-Present
Editorial Board, International Journal of Food Safety, Nutrition and Public Health, 2010-Present
Editorial Board, Topics in Integrative Health Care: An International Journal, 2010-Present
Associate Editor, European Journal of Pure and Applied Mathematics, 2007-Present.
Editorial Board, Far East Journal of Mathematics, 2006-2012
Editorial Board, Journal of Modern Applied Statistical Methods, 2002-2010
Associate Editor-Environmetric, 1992-1997
Reviewer of Scientific Journals Include
American Journal of Cardiology
American Journal of Physiology
American Journal of Public Health
American Journal of Radiology
Annals of Surgical Oncology
Arthritis Care and Research
Biometrics
Communications in Statistics
Journal of American Medical Association
Journal of Applied Statistics
Journal of Computer Science & Computational Mathematics
Journal of Comparative Neurology
Journal of Computational Statistics and Data Analysis
Journal of General Internal Medicine; Journal of School Health
Journal of Statistical Computation and Simulation
Journal of Statistical Planning and Inference
Journal of Theoretical Biology
Maternal and Child Health Journal
Medical Care
Neurobiology of Aging
Risk Analysis
Statistics in Medicine
Statistical Modeling
Statistica Neerlandica
Statistica Sinica.
External Reviewer- Faculty: Promotion, Tenure, Honors and Awards
Feinberg School of Medicine, Northwestern University
Wright State University School of Medicine
Department of Biostatistics, Colleges of Medicine and Public Health, University of Arkansas for Medical Sciences
University of Texas Medical Branch School of Medicine
Department of Epidemiology and Biostatistics, Texas A&M Health Science Center School of Rural Public Health
Department of Epidemiology and Biostatistics, University of Oklahoma Health Science Center
Department of Biostatistics, Tulane University
Department of Mathematical Sciences, University of Texas at Dallas
Department of Mathematics, Central Michigan University
Department of Statistics, King Saud University, Saudi Arabia
Department of Statistics, UAE University, United Arab Emirates

Professional Societies
American Society of Clinical Oncology
American Statistical Association
International Statistical Institute (ISI)
International Biometric Society-ENAR
The International Environmetrics Society (TIES)
Modeling and Simulation Society of Australia and New Zealand (MSSANZ)
American Public Health Association (APHA)
Academy Health
National Environmental Health Association
Institute for Diversity in Health Management