Publications

Recent Publications

 
2014

Kramer PA, Ravi S, Chacko B, Johnson MS, Darley-USmar VM. (2014) A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: Implication for their use as bioenergetics biomarkers. Redox Biol. 2:206-210. PMCID: PMC3909784.

Pasha DN, Davis JT, Rao F, Chen Y, Wen G, Fung MM, MAhata M, Zhang K, Trzebinska D, Mutapic M, Hightower CM, Lipokowitz MS, Ji M, Ziegler MG, Nievergelt CM, O’Connor DT. (2014) Heritable influence of DBH on adrenergic and renal function: twin and disease studies. PLoS One. 8(12):e82956. PMCID: PMC3876991.

Wall SB, Smith MR, Ricart K, Zhou F, Vayalil PK, Oh JY, Landar A. (2014) Detection of electrophile-sensitivie proteins. Biochim Biophys Acta. 1840(2):913-922. PMCID: PMC3858512.

2013

Aaron KJ, Sanders PW. (2013) Role of dietary salt and potassium intake in cardiovascular health and disease: a review of the evidence. Mayo Clin Proc. 88(9):987-995. PMCID: PMC3833247.

Allen CE, Sanders PW. (2013) Hypertensive nephrosclerosis: not enough of a good thing? Am J Physiol Renal Physiol. 304(6):F674-F675. PMCID: PMC3602697.

Askenazi DJ, Koralkar R, Hundley HE, Montesanti A, Patil N, Ambalavanan N. (2013) Fluid overload and mortality are associated with acute kidney injury in sick near-term/term neonate. Pediatr Nephrol. 28(4):661-666. Non-government funded study.

Barnes S, Prasain J, Kim H. (2013) In nutrition, can we “see” what is good for us? Adv Nutr. 4(3):327S-334S. PMCID: PMC3650504.

Bhanushali GK, Jain G, Fatima H, Leisch LJ, Thornley-Brown D. (2013) AKI associated with synthetic cannabinoids: a case series. Clin J Am Soc Nephrol. 8(4):523-526. PMCID: PMC3613952.

Chacko BK, Kramer PA, Ravi S, Johnson MS, Hardy RW, Ballinger SW, Darley-Usmar VM. (2013) Methods for defining distinct bioenergetics profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood. Lab Invest. 93(6):690-700. PMCID: PMC3674307.

Clement LC*, Macé C*, Avila-Casado C, Joles JA, Kersten S, Chugh SS. (2013) Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. Nat Med. [Epub ahead of print]

Cowley AW Jr, Ryan RP, Kurth T, Skelton MM, Schock-Kursch D, Gretz N. (2013) Progression of glomerular filtration rate reduction determined in conscious Dahl salt-sensitive hypertensive rats. Hypertension. 62(1):85-90. PMCID: PMC3806646.

DuPont JJ, Greaney JL, Wenner MM, Lennon-Edwards SL, Sanders PW, Farguhar WB, Edwards DG. (2013) High dietary sodium intake impairs endothelium-dependent dilation in health salt-resistant humans. J Hypertens. 31(3):530-536. PMCID Journal – In Process.

Han SM, El Oussini H, Scekic-Zahirovic J, Vibbert J, Cottee P, Prasain JK, Bellen HJ, Dupuis L, Miller MA. (2013) VAPB/AL S8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis. PLoS Genet. 9(9):e1003738. PMCID: PMC3764199.

Hoang HD, Prasain JK, Dorand D, Miller MA. (2013) A heterogenous mixture of F-series prostaglandins promotes sperm guidance in the Caenorhabditis elegans reproductive tract. PLoS Genet. 9(1):e1003271. PMCID: PMC3561059.

Hull TD, Bolisetty S, Dealmeida AC, Litovsky SH, Prabhu SD, Agarwal A, George JF. (2013) Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase. Lab Invest. 93(8):868-879. PMCID: PMC3729748.

Lewington AJ, Cerda J, Mehta RL. (2013) Raising awareness of acute kidney injury: a global perspective of a silent killer. Kidney Int. 84(3):457-467. PMCID: PMC3758780.

Merscher-Gomez S, Guzman J, Pedigo CE, Lehto M, Aguillon-Prada R, Mendez A, Lassenius MI, Forsblom C, Yoo T, Villarreal R, Maiguel D, Johnson K, Goldberg R, Nair V, Randolph A, Kretzler M, Nelson RG, Burke GW 3rd, Groop PH, Fornoni A, the FinnDiane Study Group. (2013) Cyclodextrin protects podocytes in diabetic kidney disease. Diabetes. 62(11):3817-3827. PMCID: PMC3806621.

Mitchell T, Johnson MS, Ouyang X, Chacko BK, Mitra K, Lei X, Gai Y, Moore DR, Barnes S, Zhang J, Koizumi A, Ramanadham S, Darley-Usmar VM. (2013) Dysfunctional mitochondrial bioenergetics and oxidative stress in Akit(+/Ins2)-derived β-cells. Am J Physiol Endocrinol Metab. 305(5):E585-E599. PMCID: PMC3761167.

Mrug M, Sanders PW. (2013) Beware the low HDAC11:males at risk for ischemic kidney injury. Am J Physiol Renal Physiol. 305(7):F973-F974. PMCID: PMC3798743.

Murray PT, Mehta RL, Shaw A, Ronco C, Endre Z, Kellum JA, Chawla LS, Cruz D, Ince C, Okusa MD. (2013) Current use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference. Kidney Int. [Epub ahead of print].

Pacurari M, Xing D, Hilgers RH, Guo YY, Yang Z, Hage F. (2013) Endothelial cell transfusion ameloiorates endothelial dysfunction in 5/6 nephrectomized rats.Am J Physiol Heart Circ Physiol. 305(8):H1256-H1264. PMCID: PMC3798787.

Pegues MA, McCrory MA, Zarjou A, Szalai AJ. (2013) C-reactive protein exacerbates renal ischemia-reperfusion injury. Am J Physiol Renal Physiol. 304(11): F1358-F1365. PMCID: PMC3680688.

Prasain JK, Arbshahi A, Taub PR, Sweeney S, Moore R, Sharer JD, Barnes S. (2013) Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 913-914:161-168. PMCID: PMC3779072.

Prasain JK, Hoang HD, Edmonds JW, Miller MA. (2013) Prostaglandin extraction and analysis in Caenorhabditis elegans. J Vis Exp. (76). PMCID: PMC3728984

Reily C, Mitchell T, Chacko BK, Benavides G, Murphy MP, Darley-Usmar V. (2013) Mitochondrially targeted compounds and their impact on cellular bioenergetics. Redox Biol. 1(1):86-93. PMCID: PMC3647698.

Rieg T. (2013) A high-throughput method for measurement of glomerular filtration rate in conscious mice. J Vis Exp. 75:e50330. PMCID Journal – In Process.

Rieg T, Dominguez Rieg J. (2013) Connecting type A intercalated cell metabolic state to V-ATPase function: phosphorylation does matter! Am J Physiol Renal Physiol.  305(8):F1105-F1106. PMCID: PMC3798730.

Santriano J, Sharma K. (2013) Autophagy and metabolic changes in obesity-related chronic kidney disease. Nephrol Dial Transplant. 28 Suppl4:iv29-iv36. PMCID: PMC3814227.

Santriano J, Sharma K, Blantz RC, Deng A. (2013) Induction of AMPK activity corrects early pathophysiological alterations in the subtotal nephrectomy model of chronic kidney disease. Am J Physiol Renal Physiol. 305(5):F727-F733. PMCID: PMC3761200.

Sawant A, Schafer CC, Jin TH, Zmijewski J, Tse HM, Roth J, Sun Z, Siegal GP, Thannickal VJ, Ponnazhagan S, Deshane J. (2013) Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways. Cancer Res. 72(22):6609-6620. PMCID: PMC3854493.

Sharma N, Malarkey EB, Berbari NF, O’Connor AK, Vanden Heuvel GB, Mrug M, Yoder BK. (2013) Proximal tubule proliferation is insufficient to induce rapid cyst formation after cilia disruption. J Am Soc Nephrol. 24(3):456-464. PMCID: PMC3582198.

Shimamura M, Seleme MC, Guo L, Saunders U, Schoeb TR, George JF, Britt WJ. (2013) Ganciclovir prophylaxis improves late murine cytomegalovirus induced renal allograft damage. Transplantation. 95(1):48-53. PMCID: PMC3700407.

Singh P, Ricksten SE, Bragadottir G, Redfors B, Nordquist L. (2013) Renal Oxygenation and haemodynamics in acute kidney injury and chronic kidney disease. Clin Exp Pharmacol Physiol. 40(2):138-147. PMCID: PMC3710120.

Taler SJ, Agarwal R, Bakris GL, Flynn JT, Nilsson PM, Rahman M, Sanders PW, Textor SC, Weir MR, Townsend RR. (2013) KDOQI US Commentary on the 2012 KDIGO Clinical practice guideline for management of blood pressure in CKD. Am J Kidney Dis. 62(2):201-213. PMCID: PMC3929429.

Tolwani A. (2013) Continuous Renal Replacement Therapy for Acute Kidney Injury. N Engl J Med. 368(12):1160-1161. Commentary

Wang HE, Gaurav J, Glassock RJ, Warnock DG. (2013) Comparison of Absolute Serum Creatinine Changes versus KDIGO Consensus Definitions for Characterizing Stages of Acute Kidney Injury. Nephrol Dialy Transplant. 28(6):1447-1454. PMCID: PMC3685303.

Ying WZ, Aaron KJ, Sanders PW. (2013) Transforming growth factor-β regulates endothelial function during high salt intake in rats. Hypertension. 62(5):951-956. PMCID Journal – In Process.

Zarjou A, Bolisetty S, Joseph R, Traylor A, Apostolov EO, Arosio P, Balla J, Verlander J, Darshan D, Kuhn LC, Agarwal A. (2013) Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury. J Clin Invest. 123(10):4423-4434. PMCID: PMC3784534.


 

Archived Publications

2012

Ahmed A, Fonarow GC, Zhang Y, Sanders PW, Allman RM, Arnett DK, Feller MA, Love TE, Aban IB, Levesque R, Ekundayo OJ, Dell'Italia LJ, Bakris GL, Rich MW. (2012) Renin-angiotensin inhibition in systolic heart failure and chronic kidney disease. Am J Med. 125(4):399-410. PMCID: PMC3324926

Askenazi DJ, Selewski DT, Paden ML, Cooper DS, Bridges BC, Zappitelli M, Fleming GM. (2012) Renal Replacement Therapy in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation. Clin J Am Soc Nephrol. 7(8):1328-1326. Review.

Askenazi DJ, Koralkar R, Hundley HE, Montesanti A, Parwar P, Sonjara S, Ambalavanan N. (2012) Urine Biomarkers Predict Acute Kidney Injury in Newborns. J Pediatr. 161(2):270-275. PMCID: PMC3598122.

Askenazi DJ. (2012) Do children with acute kidney injury require long-term evaluation for CKD? Am J Kidney Dis. 59(4):478-480. Commentary.

Blantz RC, Singh P, Deng A, Thomson SC, Vallon V. (2012) Acute Saline Expansion Increases Nephron Filtration and Distal Flow Rate but Maintains Tubuloglomerular Feedback Responsiveness: Role of Adenosine A1 Receptors. Am J Physiol Renal Physiol. 303(3):F405-F411. PMCID: PMC3433865

Borsting E, Cheng VP, Glass CK, Vallon V, Cunard R. (2012) Peroxisome proliferator-activated receptor-γ agonists repress epithelial sodium channel expression in the kidney. Am J Physiol Renal Physiol. 302(5):F540-F551. PMCID: PMC3353644

Bowling CB, Sanders PW, Allman RM, Rogers WJ, Patel K, Aban IB, Rich MW, Pitt B, White M, Bakris GC, Fonarow GC, Ahmed A. (2012) Effects of enalapril in systolic heart failure patients with and without chronic kidney disease: Insights from the SOLVD Treatment trial. Int J Cardiol. 167(1):151-156. PMCID: PMC3395757.

Cutter GR. (2012) Statistical cures and other fallacies. Mult Scler. 18(4):387-390. Review.

Dawoud D, Lyndon W, Mrug S, Bissler JJ, Mrug M. (2012) Impact of ultrasound-guided kidney biopsy simulation on trainee confidence and biopsy outcomes. Am J Nephrol, 36(6):570-574. PMC Journal - In Process.

Feng W, Chumley P, Hua P, Rezonzew G, Jaimes D, Duckworth MW, Xing D, Jaimes EA. (2012) Role of the Transcription factor Erythroblastosis Virus E26 Oncogen Homolog-1 (ETS-1) as Mediator of the Renal Proinflammatory and Profibrotic Effects of Angiotensin II. Hypertension. 60(5):1226-1233. PMC Journal – In Process.

Fleming GM, Askenazi DJ, Bridges BC, Cooper DS, Paden ML, Selewski DT, Zappitelli M. (2012) A Multicenter International Survey of Renal Supportive Therapy During ECMO: The Kidney Intervention During Extracorporeal Membrane Oxygenation (KIDMO) Group. ASAIO J. 58(4):407-414. PMC Journal - In Process.

Giordano S, Lee J, Darley-Usmar VM, Zhang J. (2012) Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death. PLoS One. 7(9):e44610. PMCID: PMC3435291.

Gorboulev V, Schürmann A, Vallon V, Kipp H, Jaschke A, Klessen D, Friedrich A, Scherneck S, Rieg T, Cunard R, Veyhl-Wichmann M, Srinivasan A, Balen D, Breljak D, Rexhepaj R, Parker HE, Gribble FM, Reimann F, Lang F, Wiese S, Sabolic I, Sendtner M, Koepsell H. (2012) Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes. 61(1):187-196. PMCID: PMC3237647.

Granado CD, Macedo E, Chertow GM, Soroko S, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. (2012) Toward the optimal dose metric in continuous renal replacement therapy. Int J Artif Organs. 35(6):413-424. PMC Journal - In Process.

Guo L, Agarwal A, George JF. (2012) Orthotopic Aortic Transplantation in Mice for the Study of Vascular Disease. J Vis Exp. 28(69):e4338. PMCID: PMC3565855.

Higdon AN, Benavides GA, Chacko BK, Ouyang X, Johnson MS, Landar A, Zhang J, Darley-Usmar VM. (2012) Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy. Am J Physiol Heart Circ Physiol. 302(7):H1394-H1409. PMCID: PMC3330785.

Hua P, Feng W, Rezonzew G, Chumley P, Jaimes EA. (2012) The transcription factor ETS-1 regulates angiotensin II-stimulated fibronectin production in mesangial cells. Am J Physiol Renal Physiol. 302(11) F1418-F1429. PMC Journal - In Process.

Jetton JG, Askenazi DJ. (2012) Update on acute kidney injury in the neonate. Curr Opin Peditar. 24(2):191-196. Review.

Kelpke SS, Chen B, Bradley K, Teng X, Chumley P, Moore B, Head H, Viera L, Thompson JA, Crossman DK, Bray MS, Eckhoff DE, Agarwal A, Patel RP. (2012) Sodium nitrite therapy protects against brain death induced kidney injury and improves post-transplantation outcomes. Kidney Int. 82(3):304-313. PMCID: PMC3412933.

Kennedy RE, Schneider LS, Cutter GR. (2012) Biomarker Positive and Negative Subjects in the ADNI Cohort: Clinical Characterization. Curr Alzheimer Res. 9(10):1135-1141. PMC Journal - In Process.

Kim J, Zarjou A, Traylor AM, Hull TD, Jaimes EA, George JF, Mikhail FM, Agarwal A. (2012) In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice. Kidney Int. 82(3):278-291. PMCID: PMC3396739.

Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F. (2012) G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci USA. 109(52):21462-21467. PMCID: PMC3535663.

Lang F, Vallon V. (2012) Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport. Clin Exp Nephrol. 16(1):73-80. Review

McClure M, DeLucas LJ, Wilson L, Ray M, Rowe SM, Wu X, Dai Q, Hong JS, Sorscher EJ, Kappes JC, Barnes S. (2012) Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications. Protein Eng Des Sel. 25(1):7-14. PMCID: PMC3276306.

Mehta, RL: (2012) Acute kidney injury: AKI in acute myocardial infarction-are we making progress? Nat Rev Nephrol. 8(6):322-323. Review.

Mitchell T, Darley-Usmar V. (2012) Metabolic syndrome and mitochondrial dysfunction: insights from preclinical studies with a mitochondrially targeted antioxidant. Free Radic Biol Med. 52(5):838-840. Review/Commentary.

Moskowitz-Kassai E, Mackelaite L, Chen J, Patel K, Dadhania DM, Gross SS, Chander P, Delaney V, Deng L, Chen L, Cui X, Suthanthiran M, Goligorsky MS. (2012) Excretion of anti-angiogenic proteins in patients with chronic allograft dysfunction. Nephrol Dial Transplant. 27(2):494-497. PMCID: PMC3275786.

Pan F, Goh JW, Cutter G, Su W, Pleimes D, Wang C. (2012) Long-Term Cost-Effectiveness Model of Interferon Beta-1b in the Early Treatment of Multiple Sclerosis in the United States. Clin Ther. 34(9):1966–1976. PMC Journal - In Process.

Perianayagam MC, Tighiouart H, Liangos O, Kuznetsov D, Wald R, Rao F, O’Connor DT, Jaber B. (2012) Polymorphisms in the Myeloperoxidase Gene Locus and Acute Kidney Injury: A Two-Step Genetic Association Study. Kidney Int. 82(8):909-919. PMCID: PMC3461107.

Rezonzew G, Chumley P, Feng W, Hua P, Siegal G, Jaimes EA. (2012) Nicotine exposure and the progression of chronic kidney disease: role of the 7-nicotine acetylcholine receptor. Am J Physiol Renal Physiol. 303(2):F304–F312. PMCID: PMC3404588.

Saag KG, Mohr PE, Esmail L, Mudano AS, Wright N, Beukelman T, Curtis JR, Cutter G, Delzell E, Gary LC, Harrington TM, Karkare S, Kilgore ML, Lewis CE, Moloney R, Oliveira A, Singh JA, Warriner A, Zhang J, Berger M, Cummings SR, Pace W, Solomon DH, Wallace R, Tunis SR. (2012) Improving the efficiency and effectiveness of pragmatic clinical trials in older adults in the United States. Contemp Clin Trials. 33(6):1211-1216. PMCID: PMC3675785.

Sabolic I, Vrhovac I, Eror DB, Gerasimova M, Rose M, Breljak D, Ljubojevic M, Brzica H, Sebastiani A, Thal SC, Sauvant C, Kipp H, Vallon V, Koepsell H. (2012) Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences. Am J Physiol Cell Physiol. 302(8):C1174-C1188. PMC Journal - In Process.

Sanders PW. (2012) Mechanisms of light chain injury along the tubular nephron. J Am Soc Nephrol. 23(11):1777-1781. Review

Schoeb TR, Jarmi T, Hicks JM, Henke S, Zarjou A, Hitoshi S, Kramer P, Novak J, Agarwal A, Bullard DC. (2012) eNOS inhibits the development of autoimmune-mediated vasculitis. Arthritis Rheum. 64(12):4114-4124. PMCID: PMC3510336.

Singh P, Blantz RC, Rosenberger C, Gabbai FB, Schoeb TR, Thomson SC. (2012) Aberrant tubuloglomerular feedback and HIF-1α confer resistance to ischemia after subtotal nephrectomy. J Am Soc Nephrol. 23(3):483-493. PMCID: PMC3294306.

Susantitaphong P, Perianayagam MC, Kang SW, Zhang W, Rao F, O’Connor DT, Jaber BL. (2012) Association of functional kallikrein-1 promoter polymorphisms and acute kidney injury: a case-control and longitudinal cohort study. Nephron Clin Pract. 122(3-4):107-113. PMCID: PMC3700581.

Tan CK, Carey AJ, Cui X, Webb RI, Ipe D, Crowley M, Cripps AW, Benjamin WH Jr, Ulett KB, Schembri MA, Ulett GC. (2012) Genome-wide mapping of cystitis due to Streptococcus agalactiae and Escherichia coli in mice identifies a unique bladder transcriptome that signifies pathogen-specific antimicrobial defense against urinary tract infection. Infect Immun. 80(9):3145-3160. PMCID: PMC3418756.

Taub PR, Borden K, Fard A, Maisel AS. (2012) Role of biomarkers in the diagnosis and prognosis of acute kidney injury in patients with the cardiorenal syndrome. Expert Rev Cardiovasc Ther. 10(5) 657-667: Review

Teerlink JR, Iragui VJ, Mohr JP, Carson PE, Hauptman PJ, Lovett DH, Miller AB, Piña IL, Thomson S, Varosy PD, Zile MR, Cleland JG, Givertz MM, Metra M, Ponikowski P, Voors AA, Davison BA, Cotter G, Wolko D, Delucca P, Salerno CM, Mansoor GA, Dittrich H, O'Connor D, Massie BM. (2012) The safety of an adenosine A(1)-receptor antagonist, rolofylline, in patients with acute heart failure and renal impairment: findings from PROTECT. Drug Saf. 35(3):233-244. PMC Journal - In Process.

Thomson SC, Rieg T, Miracle C, Mansoury H, Whaley J, Vallon V, Singh P. (2012) Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat. Am J Physiol Regul Integr Comp Physiol. 302(1):R75-R83. PMCID: PMC3349378.

Toney GM, Vallon V, Stockand JD. (2012) Intrinsic control of sodium excretion in the distal nephron by inhibitory purinergic regulation of the epithelial Na(+) channel. Curr Opin Nephrol Hypertens. 21(1):52-60. Review.

Vallon V, Eraly SA, Ramachandra Rao S, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T. (2012) A role for the organic anion transporter OAT3 in renal creatinine secretion in mice. Am J Physiol Renal Physiol. 302(10):F1293-F1299. PMCID: PMC3362066.

Vallon V, Thomson SC. (2012) Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney. Annu Rev Physiol. 74:351-375. Review.

Wall SB, Oh JY, Diers AR, Landar A. (2012) Oxidative modification of proteins: an emerging mechanism of cell signaling. Front Physiol.3:369. PMCID: PMC3442266.

Wang HE, Muntner P, Chertow GM, Warnock DG. (2012) Acute kidney injury and mortality in hospitalized patients. Am J Nephrol. 35(4):349-355. PMCID: PMC3362180.

Ying WZ, Aaron KJ, Sanders PW. (2012) Effect of agingand dietary salt and potassium intake on endothelial PTEN (Phosphatase and tensin homolog on chromosome 10) function. PLoS ONE. 7(11):e41785. PMCID: PMC3492426.

Ying WZ, Allen CE, Curtis LM, Aaron KJ, Sanders PW. (2012) Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model. J Clin Invest. 122(5):1777-1785. PMCID: PMC3336971.

Ying WZ, Wang PX, Sanders PW. (2012) Pivotal role of apoptosis signal-regulating kinase 1 in monoclonal free light chain-mediated apoptosis. Am J Pathol. 180(1):41-47. PMCID: PMC3338338.

Zarjou A, Sanders PW, Mehta RL, Agarwal A. (2012) Enabling innovative translational research in acute kidney injury. Clin Transl Sci. 5(1):93-101. PMCID: PMC3292183.

Zarjou A, Agarwal A. (2012) Heme oxygenase-1 as a target for TGF-β in kidney disease. Semin Nephrol. 32(3):277-286. PMCID: PMC3407376

Zarjou A, Guo L, Sanders PW, Mannon RB, Agarwal A, George JF. (2012) A reproducible mouse model of chronic allograft nephropathy with vasculopathy. Kidney Int. 82(11):1231-1235. PMCID: PMC3495090.

Zhou J, Ouyang X, Schoeb TR, Bolisetty S, Cui X, Mrug S, Yoder BK, Johnson MR, Szalai AJ, Mrug M. (2012) Kidney Injury Accelerates Cystogenesis via Pathways Modulated by Heme Oxygenase and Complement. J Am Soc Nephrol. 23(7):1161-1171. PMCID: PMC3380643.

2011

Aaron KJ, Campbell RC, Judd SE, Sanders PW, Muntner P. (2011) Association of dietary sodium and potassium intakes with albuminuria in normal-weight, overweight, and obese participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Clin Nutr. 94(4):1071-1078. PMCID: PMC3173025.

Anderson JT, Zeng M, Li Q, Stapley R, Moore DR 2nd, Chenna B, Fineberg N, Zmijewski J, Eltoum IE, Siegal GP, Gaggar A, Barnes S, Velu SE, Thannickal VJ, Abraham E, Patel RP, Lancaster JR Jr, Chaplin DD, Dransfield MT, Deshane JS. (2011) Elevated levels of NO are localized to distal airways in asthma. Free Radic Biol Med. 50(11):1679-1688. PMCID: PMC3124865.

Askenazi DJ, Koralkar R, Levitan EB, Goldstein SL, Devarajan P, Khandrika S, Mehta RL, Ambalavanan N. (2011) Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants. Pediatr Res. 70(3):302-306. PMCID: PMC3152663.

Bell PD, Fitzgibbon W, Sas K, Stenbit AE, Amria M, Houston A, Reichert R, Gilley S, Siegal GP, Bissler J, Bilgen M, Chou PC, Guay-Woodford L, Yoder B, Haycraft CJ, Siroky B. (2011) Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis. J Am Soc Nephrol. 22(5):839-848. PMCID: PMC3083306.

Blantz RC, Singh P. (2011) Analysis of the Prerenal Contributions to Acute Kidney Injury. Contrib Nephrol. 174:4-11. Review.

Bolisetty S, Agarwal A. (2011) Urine albumin as a biomarker in acute kidney injury. Am J Physiol Renal Physiol. 300(3):F626-F627. PMCID: PMC3064133.

Bowling CB, Feller MA, Mujib M, Pawar PP, Zhang Y, Ekundayo OJ, Aban IB, Love TE, Sanders PW, Anker SD, Fonarow GC, Ahmed A. (2011) Relationship between stage of kidney disease and incident heart failure in older adults. Am J Nephrol. 34(2):135-141. PMCID: PMC3136373.

Buckoreelall K, Wilson L, Parker WB. (2011) Identification and characterization of two adenosine phosphorylase activities in Mycobacterium smegmatis. J Bacteriol. 193(20):5668-5674. PMCID: PMC3187226.

Clement LC, Avila-Casado C, Macé C, Soria E, Bakker WW, Kersten S, Chugh SS. (2011) Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med. 17(1):117-122. PMCID: PMC3021185.

Dranka BP, Benavides GA, Diers AR, Giordano S, Zelickson BR, Reily C, Zou L, Chatham JC, Hill BG, Zhang J, Landar A, Darley-Usmar VM. (2011) Assessing bioenergetic function in response to oxidative stress by metabolic profiling. Free Radic Biol Med. 51(9):1621-1635. PMCID: PMC3548422.

Du Y, Zappitelli M, Mian A, Bennett M, Ma Q, Devarajan P, Mehta R, Goldstein SL. (2011) Urinary biomarkers to detect acute kidney injury in the pediatric emergency center. Pediatr Nephrol. 26(2):267-274. PMC Journal – In Process.

Filippatos GS, Ahmed MI, Gladden JD, Mujib M, Aban IB, Love TE, Sanders PW, Pitt B, Ankar SD, Ahmed A. (2011) Hyperuricaemia, chronic kidney disease, and outcomes in heart failure: potential mechanistic insights from epidemiological data. Eur Heart J. 32(6):712-720. PMCID: PMC3056205.

Floyd KA, Stella DR, Wang CC, Laurentz S, McCabe GP, Srivastava OP, Barnes S. (2011) Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat. Exp Eye Res. 92(2):120-127. PMCID: PMC3034771.

Granado CD, Macedo E, Soroko S, Chertow GM, Himmelfarb J, Ikizler AT, Paganini EP, Mehta RL. (2011) Effluent volume in continuous renal replacement therapy overestimates the delivered dose of dialysis. Clin J Am Soc Nephrol. 6(3):467-475. PMCID: PMC3082402.

Granado CD, Mehta RL. (2011) Withholding and withdrawing renal replacement support in AKI. Semin Dial. 24(2):208-214. Review

Granado CD, Mehta RL. (2011) Assessing and delivering dialysis dose in AKI. Semin Dial. 24(2):157-163. Review.

Horikawa YT, Panneerselvam M, Kawaraguchi Y, Tsutsumi YM, Ali SS, Balijepalli RC, Murray F, Head BP, Niesman IR, Rieg T, Vallon V, Insel PA, Patel HH, Roth DM. (2011) Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and  increases natriuretic peptide expression and signaling. J Am Coll Cardiol. 57(22):2273-2283. PMCID: PMC3236642.

Hutchison CA, Batuman V, Behrens J, Bridoux F, Sirac C, Dispenzieri A, Herrera GA, Lachmann H, Sanders PW. (2011) International Kidney and Monoclonal Gammopathy Research Group. The pathogenesis and diagnosis of acute kidney injury in multiple myeloma. Nat Rev Nephrol. 8(1):43-51. PMCID: PMC3375610.

Kanbay M, Chen Y, Solak Y, Sanders PW. (2011) Mechanisms and consequences of salt sensitivity and dietary salt intake. Curr Opin Nephrol Hypertens. 20(1):37-43. PMCID: PMC3089903.

Kang SW, Shih PA, Mathew RO, Mahata M, Biswas N, Rao F, Yan L, Bouchard J, Malhotra R, Tolwani A, Khandrika S, Mehta RL, O'Connor DT. (2011) Renal kallikrein excretion and epigenetics in human acute kidney injury: Expression, mechanisms and consequences. BMC Nephrol. 12:27. PMCID: PMC3154145.

Lee SA, Belyaeva OV, Wu L, Kedishvili NY. (2011) Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture. J Biol Chem. 286(15):13550-13560. PMCID: PMC3075701.

Li FJ, Kubagawa Y, McCollum MK, Wilson L, Motohashi T, Bertoli LF, Barton JC, Barnes S, Davis RS, Kubagawa H. (2011) Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (FcμR) in patients with chronic lymphocytic leukemia. Blood. 118(18):4902-4909. PMCID: PMC3208298.

Li F, Glinskii OV, Zhou J, Wilson LS, Barnes S, Anthony DC, Glinsky VV. (2011) Identification and analysis of signaling networks potentially involved in breast carcinoma metastasis to the brain. PLoS One. 6(7) e21977. PMCID: PMC3136937.

Lu A, Miao M, Schoeb, TR, Agarwal A, Murphy-Ullrich JE. (2011) Blockade of TSP1-dependent TGF-β activity reduces renal injury and proteinuria in a murine model of diabetic nephropathy. Am J Pathol. 178(6):2573-2586. PMCID: PMC3124297.

Macedo E, Malhotra R, Claure-Del Granado R, Fedullo P, Mehta RL. (2011) Defining urine output criterion for acute kidney injury in critically ill patients. Nephrol Dial Transplant. 26(2):509-515. PMCID: PMC3108356.

Mehta RL. (2011) Management of acute kidney injury: it's the squeaky wheel that gets the oil! Clin J Am Soc Nephrol. 6(9):2102-2104. Review.

Mehta RL, Bouchard J, Soroko S, Ikizler TA, Paganini EP, Chertow GM, Himmelfarb J. (2011) Sepsis as a Cause and Consequence of Acute Kidney Injury: Program to Improve Care in Acute Renal Disease (PICARD). Intensive Care Med. 37(2):241-248. PMCID: PMC3028102.

Mehta RL. (2011) Biomarker explorations in acute kidney injury: the journey continues. Kidney Int. 80(4):332-334. Review.

Perianayagam MC, Tighiouart H, Nievergelt CM, O'Connor DT, Liangos O, Jaber BL. (2011) CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study. Nephron Extra. 1(1):112-123. PMCID: PMC3290849.

Rajbhandari R, Peng N, Moore R, Arabshahi A, Wyss JM, Barnes S, Prasain JK. (2011) Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry. J Agric Food Chem. 59(12):6682-6688. PMCID: PMC3165050.

Rieg T, Gerasimova M, Boyer JL, Insel PA, Vallon V. (2011) P2Y2‚ receptor activation decreases blood pressure and increases renal Na+ excretion. Am J Physiol Regul Integr Comp Physiol. 301(2):R510-R518. PMCID: PMC3154711

Sanders PW. (2011) Light chain-mediated tubulopathies. Contrib Nephrol. 169:262-269. Review.

Shimamura M, Saunders U, Rha B, Guo L, Cassady KA, George JF, Britt WJ. (2011) Ganciclovir transiently attenuates murine cytomegalovirus-associated renal allograft inflammation. Transplantation. 92(7):759-766. PMC Journal – In Process.

Singh P, Okusa MD. (2011) Role of Tubuloglomerular Feedback in the Pathogenesis of AKI. Controversies in Acute Kidney Injury. Contrib Nephrol. 174:12-21. Invited review.

Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. (2011) Functional Maturation of Drug Transporters in the developing, neonatal and postnatal Kidney. Mol Pharmacol. 80(1):147-154. PMCID: PMC3127534.

Thomson SC, Blantz RC. (2011) Biophysical basis of glomerular filtration. In Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology, Fifth Edition, Alpern RJ, Caplan M, and Moe OW (Eds) In Press 2011.  Book Chapter.

Thomson SC, Blantz RC. (2011) Glomerular filtration rate. In Comprehensive Physiology.  Pollack DM, Garvin J (eds), In Press, 2011. Book Chapter.

Vallon V, Komers R. (2011) Pathophysiology of the diabetic kidney. Comp Physiol. 1(3):1175-1232. Review.

Vallon V, Platt KA, Cunard R, Schroth J, Whaley J, Thomson SC, Koepsell H, Rieg T. (2011) SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol. 22(1):104-112. PMCID: PMC3014039

Vallon V, Rieg T. (2011) Regulation of renal NaCl and water transport by the ATP/UTP/P2Y2 receptor system. Am J Physiol Renal Physiol. 301(3):F463-F475. PMCID: PMC3174559.

Vallon V, Thomson S. (2011) Anomalous role for dietary salt in diabetes mellitus? Nat Rev Endocrinol.7(7):377-378. PMCID: PMC3335262.

Vallon V. (2011) The proximal tubule in the pathophysiology of the diabetic kidney. Am J Physiol Regul Integr Comp Physiol. 300(5):R1009-R1022. PMCID: PMC3094037

Vallon V. (2011) Molecular determinants of renal glucose reabsorption focus on “Glucose transport by human renal Na+-d-glucose co-transporters SGLT1 & SGLT2”. Am J Physiol Cell Physiol. 300(1):C6-C8. PMCID: PMC3023181.

Weigent DA. (2011) High molecular weight isoforms of growth hormone in cells of the immune system. Cell Immunol. 271(1):44-52. PMC Journal – In Process.

Wu QQ, Wang Y. Senitko M, Meyer C, Wigley CW. Ferguson DA, Grossman E, Chen J, Zhou ZJ, Hartono J, Winterberg P. Chen B, Agarwal A, Lu CY. (2011) Bardoxolone Methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes - Nrf2, PPARγ, and HO-1. Am J Physiol Renal Physiol. 300(5):F1180-F1192. PMCID: PMC3094059.

Ying WZ, Wang PX, Aaron KJ, Basnayake K, Sanders PW. (2011) Immunoglobulin light chains activate nuclear factor-β in renal epithelial cells through a Src-dependent mechanism. Blood. 117(4):1301-1307. PMCID: PMC3056473.

Zarjou, A, Agarwal A. (2011) Sepsis and acute kidney injury. J Am Soc Nephrol. 22(6):999-1006. Review.

Zarjou A, Kim J, Traylor AM, Sanders PW, Balla J, Agarwal A, Curtis LM. (2011) Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1. Am J Physiol Renal Physiol. 300(1):F254-F262. PMCID: PMC3023217.

Zarjou A, Yang S, Abraham E, Agarwal A, Liu G. (2011) Identification of a microRNA signature in renal fibrosis: Role of miR21. Am J Physiol Renal Physiol. 301(4):F793-F801. PMCID: PMC3191802.

Zavaczki E, Jeney V, Agarwal A, Zarjou A, Oros M, Katko M, Varga Z, Balla G, Balla J. (2011) Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells. Kidney Int. 80(7):731-739. PMCID: PMC3257044.

Zhang Y, Fonarow GC, Sanders PW, Farahmand F, Allman RM, Aban IB, Love TE, Levesque R, Kilgore ML, Ahmed A. (2011) A propensity-matched study of the comparative effectiveness of angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors in heart failure patients age ≥ 65 years. Am J Cardiol. 108(10):1443-1448. PMCID: PMC3324944.

Zheng Y, Qin H, Frank SJ, Deng L, Litchfield DW, Tefferi A, Pardanani A, Lin  FT, Li J, Sha B, Benveniste EN. (2011) A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway. Blood. 118(1):156-166. PMCID: PMC3139382.

2010

Alam A, O'Connor DT, Perianayagam MC, Kolyada AY, Chen Y, Rao F, Mahata M, Mahata S, Liangos O, Jaber BL. (2010) Phenylethanolamine N-Methyltransferase Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury. Nephron Clin Pract. 114(4):c253-c259. PMCID: PMC2865401.

Basnayake K, Ying WZ, Wang PX, and Sanders P. (2010) Immunoglobulin Light Chains Activate Tubular Epithelial Cells Through Redox Signaling. J Am Soc Nephrol. 21(7):1165-1173. PMCID: PMC3152234.

Bhatnagar V, Garcia EP, O’Connor DT, Brophy VH, Alcaraz J, Richard E, Bakris GL, Middleton JP, Norris KC, Wright J, Hiremath L, Contreras G, Appel LJ, Lipkowitz MS, AASK Study Investigators. (2010) CYP3A4 and CYP3A5 Polymorphisms and Blood Pressure Response to Amlodipine among African-American Men and Women with Early Hypertensive Renal Disease. Am J Nephrol. 31(2):95-103. PMCID: PMC2853591.

Bolisetty S, Traylor AM, Kim J, Joseph R, Ricart K, Landar A, Agarwal A. (2010) Heme oxygenase-1 inhibits renal tubular macroautophagy in acute kidney injury. J Am Soc Nephrol. 21(10):1702-1712. PMCID: PMC3013546.

Bouchard J, Macedo E, Mehta RL. (2010) Dosing of Renal Replacement Therapy in Acute Kidney Injury: Lessons Learned From Clinical Trials. Am J Kidney Dis. 55(3):570-579. Review.

Bouchard J, Macedo E, Soroko S, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. (2010) Comparison of methods for estimating glomerular filtration rate in critically ill patients with acute kidney injury. Nephrol Dial Transplant. 25(1):102-107. PMCID: PMC2910324.

Bouchard J, Mehta RL. (2010) Fluid Balance Issues in the Critically Ill Patient. Contrib Nephrol. 164:69. Review.

Bowling CB, Pitt B, Ahmed MI, Aban IB, Sanders PW, Mujib M, Campbell RC, Love TE, Aronow WS, Allman RM, Bakris GL, Ahmed A. (2010) Hypokalemia and outcomes in patients with chronic heart failure and chronic kidney disease: findings from propensity-matched studies. Circ Heart Fail. 3(2):253-260. PMCID: PMC2909749.

Chacko BK, Reily C, Srivastava A, Johnson MS, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V. (2010) Prevention of diabetic nephropathy in the Ins2+/-Akita J mice by the mitochondria-targeted therapy Mito-Q. Biochem J. 432(1):9-19. PMCID: PMC2973231.

Chen Y, Lipkowitz MS, Salem RM, Fung MM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Hicks PJ, Bowden DW, Freedman BI, O’Connor DT. (2010) Progression of chronic kidney disease (CKD): Adrenergic genetic influence on GFR decline in hypertensive nephrosclerosis. Am J Nephrol. 32(1):23-30. PMCID: PMC2914391.

Chen Y, Rao F, Wen G, Gayen JR, Zhang K, Vaingankar SM, Biswas N, Mahata M, Friese RS, Fung MM, Salem RM, Nievergelt C, Bhatnagar V, Hook VY, Ziegler MG, Mahata SK, Hamilton BA, O’Connor DT. (2010) Naturally occurring genetic variants in human chromogranin A (CHGA) associated with hypertension as well as hypertensive renal disease. Cell Mol Neurobiol. 30(8):1395-1400. PMCID: PMC3008929.

Chen Y, Salem RM, Rao F, Fung MM, Bhatnagar V, Pandey B, Mahata M, Waalen J, Nievergelt CM, Lipkowitz MS, Hamilton BA, Mahata SK, O'Connor DT. (2010) Common charge-shift mutation Glu65Lys in K+ channel β1‚ -Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease. Am J Nephrol. 32(5):414-424. PMCID: PMC2975731

Deng A, Arndt MA, Satriano J, Singh P, Rieg T. (2010) Renal Protection in Chronic Kidney Disease: Hypoxia Inducible Factor Activation Versus Angiotensin II Blockade. Am J Physiol Renal Physiol. 299:(6):F1365-F1373.  PMCID: PMC3006314.

Deshane J, Kim J, Bolisetty S, Hock TD, Hill-Kapturczak N, Agarwal A. (2010) Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells. J Biol Chem. 285(22):16476-16486. PMCID: PMC2878004.

Diers AR, Higdon AN, Ricart KC, Johnson MS, Agarwal A, Kalyanaraman B, Landar A, Darley-Usmar VM. (2010) Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12, 14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. Biochem J. 426(1):31-41. PMCID: PMC3079364.

Edmonds JW, Prasain JK, Dorand D, Yang Y, Hoang HD, Vibbert J, Kubagawa HM, Miller MA. (2010) Insulin/FOXO signaling regulates ovarian prostaglandins critical for reproduction. Dev Cell. 19(6):858-871. PMCID: PMC3026445.

Fogo AB, Bostad L, Svarstad E, Molls S, Barbey F, Geldenhuys L, West M, Ferluga D, Vujkovac B, Howie AJ, Burns A, Waldek S, Noel LH, Grunfeld JP, Valbuena C, Oliveira JP, Muller J, Brunig F, Zhang X, Warnock WG. (2010) Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN). Nephrol Dial Transplant. 25(7):2168-2177. PMCID: PMC2902894.

George J, Agarwal A. (2010) Hydrogen: another gas with therapeutic potential. Kidney Int. 77(2):85-87. Review.

Hellman NE, Liu Y, Merkel E, Austin C, Le Corre S, Beier DR, Sun Z, Sharma N, Yoder BK, Drummond IA. (2010) The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proc Natl Acad Sci USA. 107(43):18499-18504. PMCID: PMC2972951.

Higdon AN, Dranka BP, Hill BG, Oh JY, Johnson MS, Landar A, Darley-Usmar VM. (2010) Methods for imaging and detecting modification of proteins by reactive lipid species. Free Radic Biol Med. 47(3):201-212. PMCID: PMC2727357.

Lang F, Huang DY, Vallon V. (2010) SGK, renal function and hypertension. J Nephrol. 23 Suppl 16:S124-S129. Review

Macedo E, Bouchard J, Soroko SH, Chertow GM, Himmelfarb J, Ikizker TA, Paganini EP. Mehta RL. (2010) Fluid accumulation, recognition and staging of acute kidney injury in critically-ill patients. Crit Care. 14(3):R82. PMCID: PMC2911707.

Macedo E, Mehta RL. (2010) Early vs Late start of dialysis: it’s all about timing. Crit Care. 14(1):112. PMCID: PMC2875487.

Macedo E, Mehta RL. (2010) Prerenal Azotemia in Congestive Heart Failure. Contrib Nephrol. 164:79-87. Review.

Mehta RL. (2010) Timed and targeted therapy for acute kidney injury: a glimpse of the future. Kidney Int. 77(11):947-949. Review.

Mrug M, Bissler J. (2010) Simulation of real-time ultrasound-guided renal biopsy. Kidney Int. 78(7):705-707. PMCID: PMC3420353.

Parks DJ, Agarwal A, George JF. (2010) Heme oxygenase-1 Expression in murine dendritic cell subpopulations: Effect on CD8+ dendritic cell differentiation in vivo. Am J Pathol. 176(6):2831-2839. PMCID: PMC2877844.

Pochynyuk O, Rieg T, Bugaj V, Schroth J, Fridman A, Boss GR, Insel PA, Stockand JD, Vallon V. (2010) Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2 receptor tone. FASEB J. 24(6):2056-2065. PMCID: PMC2874475.

Rieg T, Tang T, Murray F, Schroth J, Insel PA, Fenton RA, Hammond HK, Vallon V. (2010) Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in renal inner medulla. J Am Soc Nephrol. 21(12):2059-2068. PMCID: PMC3014019.

Rodriguez-Flores JL, Zhang K, Kang SW, Wen G, Ghosh S, Friese RS, Mahata SK, Subramaniam S, Hamilton BA, O’Connor DT. (2010) Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/ experimental approach. Mamm Genome. 21(3-4):195-204. PMCID: PMC2844968.

Salem RM, O’Connor DT, Schork NJ. (2010) Curve-Based Multivariate Distance Matrix Regression (CMDMR) Analysis: Application to Genetic Association Analyses Involving Repeated Measures. Physiol Genomics. 42(2):236-247. PMCID: PMC3032281.

Sanders PW, Agarwal A. (2010) Acute Kidney Injury. ACP Medicine, A textbook of Medicine published by the American College of Physicians. Editor-in-chief – Elizabeth G. Nabel, MD. Decker Intellectual Properties, Hamilton, ON L8N 3K7, Canada. Book Chapter

Satriano J, Mansoury H, Deng A, Sharma K, Vallon V, Blantz RC, Thomson SC. (2010) Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes. Am J Physiol Cell Physiol. 299(2):C374-C380. PMCID: PMC2928628.

Singh P, Rifkin DE, Blantz RC. (2010) Chronic kidney disease: an inherent risk factor for acute kidney injury? Clin J Am Soc Nephrol. 5(9):1690-1695. Review.

Singh P, Thomson SC. (2010) Renal homeostasis and tubuloglomerular feedback. Curr Opin Nephrol Hypertens. 19(1):59-64. Review.

Snelgrove RJ, Jackson PL, Hardison MT, Noerager BD, Kinloch A, Gaggar A, Shastry S, Rowe SM, Shim YM, Hussell T, Blalock JE. (2010) A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation. Science. 330(6000):90-94. PMCID: PMC3072752.

Thomson SC, Blantz RC. (2010) A new role for charge of the glomerular capillary membrane. J Am Soc Nephrol. 21(12):2011-2013. Review.

Vallon V, Sharma K. (2010) Sodium-glucose transport: role in diabetes mellitus and potential clinical implications. Curr Opin Nephrol Hyperten. 19(5):425-431. Review.

Zhou J, Ouyang X, Cui X, Schoeb TR, Smythies LE, Johnson MR, Guay-Woodford LM, Chapman AB, Mrug M. (2010) Renal CD14 expression correlates with the progression of cystic kidney disease. Kidney Int. 78(6):550-560. PMCID: PMC3422025.

2009

Arndt MA, Battaglia V, Parisi E, Lortie MJ, Isome M, Baskerville C, Pizzo DP, Ientile R, Colombatto S, Toninello A, Satriano J. (2009) The arginine metabolite agmatine protects mitochondrial function and confers resistance to cellular apoptosis. Am J Physiol Cell Physiol. 296(6):C1411-C1419. PMCID: PMC2692420.

Bolisetty S, Agarwal A. (2009) Neutrophils and acute kidney injury: Not neutral any more. Kidney Int. 75(7):674-676. Review.

Bouchard J, Mehta RL. (2009) Volume management in continuous renal replacement therapy. Semin Dial. 22(2):146-150. Review.

Bouchard J, Mehta RL. (2009) Fluid accumulation and acute kidney injury: consequence or cause. Curr Opin Crit Care. 15(6):509-513. Review.

Chen B, Guo L, Fan C, Bolisetty S, Joseph R, Wright MM, Agarwal A, George J. (2009) Carbon monoxide rescues heme oxygenase-1 deficient mice from arterial thrombosis in allogenic aortic transplantation. Am J Pathol. 175(1):422-429. PMCID: PMC2708827.

Chen Y, Mahata M, Rao F, Khandrika S, Courel M, Fung MM, Zhang K, Stridsberg M, Ziegler MG, Hamilton BA, Lipkowitz MS, Taupenot L, Nievergelt C, Mahata SK, O’Connor DT. (2009) Chromogranin A Regulates Renal Function by Triggering Weibel-Palade Body Exocytosis. J Amer Soc Nephrol. 20(7):1623-1632. Topic of editorial. PMCID: PMC2709688.

Cui X, Zhou J, Qiu J, Johnson MR, Mrug M. (2009) Validation of endogenous internal real-time PCR controls in renal tissues. Am J Nephrol. 30(5):413-417. PMCID: PMC2818397

Deng A, Tang T, Singh P, Wang C, Satriano J, Thomson S, Blantz RC. (2009) Regulation of oxygen utilization by angiotensin II in chronic kidney disease. Kidney Int. 75:197-204. PMCID: PMC3151651.

Friese RS, Rao F, Khandrika S, Thomas BG, Ziegler MG, Schmid-Schonbein GW, O'Connor DT. (2009) Matrix metalloproteinases: Discrete elevations in essential hypertension and hypertensive end-stage renal disease. Clin Exp Hypertens. 31(7):521-533. PMCID: PMC2875383.

Fung MM, Chen Y, Lipkowitz MS, Salem RM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Brophy VH, O’Connor DT, for the AASK co-investigators. (2009) Adrenergic Beta-1 Receptor Genetic Variation Predicts Longitudinal Rate Of GFR Decline In Hypertensive Nephrosclerosis. Nephrol Dial Transplant. 24(12):3677-3686. PMCID: PMC2790952.

Fung MM, O'Connor DT. (2009) Complex renal traits: role of adrenergic genetic polymorphism. J Am Soc Nephrol. 20(6):1172-1174. Review.

Fung MM, Rana BK, Tang CM, Shiina T, Nievergelt C, Rao F, Salem RM, Waalen J, Ziegler MG, Insel PA, O’Connor DT. (2009) Dopamine D1 Receptor (DRD1) Genetic Polymorphism G-94A: Pleiotropic Effects On Heritable Renal Traits. Kidney Int. 76(10):1070–1080. PMCID: PMC2803094.

Hill BG, Reily C, Oh JY, Johnson MS, Landar A. (2009) Methods for the determination and quantification of the reactive thiol proteome. Free Radic Biol Med. 47(6):675-683. PMCID: PMC2759107.

Khosla N, Soroko SB, Chertow GM, Himmelfarb J, Ikizler TA, Paganini E, Mehta RL. (2009) Preexisting Chronic Kidney Disease: A potential for improved outcomes from acute kidney injury. Clin J Am Soc Nephrol. 4(12):1914-1919. PMCID: PMC2798877

Lang F, Artunc F, Vallon V. (2009) The physiological impact of the serum and glucocorticoid-inducible kinase SGK1. Curr Opin Nephrol Hypertens. 18(5):439-448. PMCID: PMC2883450.

Lortie M, Bark S, Blantz R, Hook V. (2009) Detecting low abundance vasoactive peptides in plasma; progress towards absolute quantitation using nano LC-MS. Anal Biochem. 394(2):164-170. PMCID: PMC2745394.

Macedo E, Bouchard J, Mehta RL. (2009) Renal replacement therapy for acute renal failure. Minerva Urol Nefrol. 61(3):189-204. Review

Macedo E, Mehta RL. (2009) Prerenal failure: from old concepts to new paradigms. Curr Opin Crit Care. 15(6):467-473. Review.

Okusa MD, Chertow GM, Portilla D, Agarwal A, Acute Kidney Injury Advisory Group of the American Society of Nephrology. (2009) The nexus of acute kidney injury, chronic kidney disease, and World Kidney Day 2009. Clin J Am Soc Nephrol. 4(3):520-522. Review.

Ricart KC, Bolisetty S, Johnson MS, Perez J, Agarwal A, Murphy MP, Landar A. (2009) The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. Biochem J. 419(2):427-436. PMCID: PMC2737281.

Rieg T, Vallon V. (2009) ATP and adenosine in the local regulation of water transport and homeostasis by the kidney. Am J Physiol Regul Integr Comp Physiol. 296(2): R419-R427. PMCID: PMC2643977.

Sanders, PW. (2009) Dietary Salt Intake, Salt Sensitivity, and Cardiovascular Health. Hypertension. 53(3):442-445. PMCID: PMC2678240.

Sanders, PW. (2009) Vascular consequences of dietary salt intake. Am J Physiol Renal Physiol. 297(2):F237-F243. PMCID: PMC2724242.

Singh P, Deng A, Blantz RC, Thomson SC. (2009) Unexpected effect of angiotensin AT-1 receptor blockade on tubuloglomerular feedback in early subtotal nephrectomy. Am J Physiol Renal Physiol. 2009, 296, F1158-65.  PMCID:  PMC2681370.

Vallon V, Hummler E, Rieg T, Pochynyuk O, Bugaj V, Schroth J, Dechenes G, Rossier B, Cunard R, and Stockand J. (2009) Thiazolidinedione-induced fluid retention is independent of collecting duct alpha ENaC activity. J Am Soc Nephrol. 20(4):721-729. PMCID: PMC2663822.

Vallon V, Osswald H. (2009) Adenosine receptors and the kidney. In: Handbook of Experimental Pharmacology 193: Adenosine Receptors in Health and Disease, C.N. Wilson and S.J. Mustafa (eds.), Springer-Verlag Berlin Heidelberg, pp 443-470.

Vallon V, Schroth J, Lang F, Kuhl D, Uchida S. (2009) Expression and phosphorylation of the Na+-Cl cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1.Am J Physiol Renal Physiol. 297(3):F704-F712. PMCID: PMC2739704.

Vallon V, Schroth J, Satriano J, Blantz RC, Thomson SC, Rieg T. (2009) Adenosine A1 receptors determine glomerular hyperfiltration and the salt paradox in early streptozotocin diabetes mellitus. Nephron Physiol.111(3):30-38. PMCID: PMC2904473.

Wright MM, Kim J, Hock TD, Leitinger N, Freeman BA, Agarwal A. (2009) Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions. Biochem J. 422(2):353-361. PMCID: PMC2881470.

Ying WZ, Aaron K, Wang PX, Sanders PW. (2009) Potassium inhibits dietary salt-induced TGF-ß production. Hypertension. 54(5):1159-1163. PMCID: PMC2766016.