Recent Publications


2017

  • Alasmari F, Crotty Alexander LE, Nelson JA, Schiefer IT, Breen E, Drummond CA, Sari Y. (2017) Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate trasnporters and α-7 nicotinic acetylocholine receptor in female CD-1 mice. Prog Neuropsychopharmacol Biol Psychiatry. 77:1-8. PMCID: PMC5466499.
  • Awisidhu L, Mehta RL. (2017) The 6R’s of drug induced nephrotoxicity. BMC Nephrol. 28(1):124. PMCID: PMC5379580.
  • Baddam S, Cutter GR, Wolfson JA, Friedman GK, Lebensburger JD. (2017) Publication outcomes of abstrats from the American Society of Hematology Annual Meeting. Am J Hematol. 92(5):E81-E83. PMCID: PMC5389908.
  • Balena-Borneman J, Ambalavanan N, Tiwari HK, Griffin RL, Halloran B, Askenazi D. (2017) Biomarkers associated with bronchopulmonary dysplasia/mortality in premature infants. Pediatr Res. 81(3):519-525. PMCID: PMC5373977.
  • Bolisetty S, Zarjou A, Agarwal A. (2017) Heme Oxygenase 1 as a Therapeutic Target in Acute Kidney Injury. Am J Kidney Dis. 69(4):531-545. PMCID: PMC5407734
  • Cui S, Vaingankar SM, Stenger A, Waikar SS, Leaf DE. (2017) Stability of Fibroblast Growth Factor 23 in Human Plasma. J Appl Lab Med. [Epub ahead of press]
  • De Miguel C, Hamrick WC, Hobbs JL, Pollock DM, Carmines PK, Pollock JS. (2017) Endothelin receptor-specific control of endoplasmic reticulum stress and apoptosis in the kidney. Sci Rep. 7:43152. PMCID: PMC5322462.
  • Feng W, Dell'Italia LJ, Sanders PW. (2017) Novel Paradigms of Salt and Hypertension. J Am Soc Nephrol. 28(5):1362-1369. PMCID: PMC5407734.
  • Guan Z, Wang F, Cui X, Inscho EW. (2017) Mechanisms of Sphingosine-1 phosphate-mediated Vasoconstriction of Rat Afferent Arterioles. J Acta Physiologica. In Press.
  • Hallow KM, Gebremichael Y, Helmlinger G, Vallon V. (2017) Primary proximal tubule hyperreabsorption and impaired tubular transport counterregulation determine glomerular hyperfiltration in diabetes: a modeling analysis. Am J Physiol Renal Physiol. 312(5):F819-F835. PMCID: PMC5451553.
  • Hepokoski M, Englert JA, Baron RM, Crotty-Alexander LE, Fuster MM, Beitler JR, Malhotra A, Singh P. (2017) Ventilator-induced lung injury increases expression of endothelial inflammatory mediators in the kidney. Am J Physiol Renal Physiol. 312(4):F654-F660. PMCID: PMC5407070.
  • Hull TD, Agarwal A, Hoyt K. (2017) Brief Review: Application of Ultrasound Imaging to Understand the Pathophysiology of AKI and CKD. J Am Soc Nephrol. Accepted for Publication.
  • Kramann R, Wongboonsin J, Chang-Panesso M, Machado FG, Humphreys BD. (2017) Gli1+ Pericyte Loss Induces Capillary Rarefaction and Proximal Tubular Injury. J Am Soc Nephrol. 28(3):776-784. PMCID: PMC5328159.
  • Layton AT, Edwards A, Vallon V. (2017) Adaptive changes in GFR, tubular morphology and transport in subtotal nephrectomized kidneys: modeling and analysis. Am J Physiol Renal Physiol. [Epub ahead of print]
  • Lebensburger JD, Cutter GR, Howard TH, Muntner P, Feig DI. (2017) Evaluating risk factors for chronic kidney disease in pediatric patients with sickle cell anemia. Pediatr Nephrol. [Epub ahead of print]
  • Pang P, Abbott M, Chang SL, Abdi M, Chauhan N, Mistri M, Ghofrani J, Fucci QA, Walker C, Leonardi C, Grady S, Halim A, Hoffman R, Lu T, Cao H, Tullis SG, Malek S, Kumar S, Steele G, Kibel A, Freedman BS, Waikar SS, Siedlecki AM. (2017) Human vascular protenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks. Kidney Int. 91(1):129-143. PMCID: PMC179298.
  • Pike D, Shiu YT, Somarathna M, Guo L, Isayeva T, Totenhagen J, Lee T. (2017) High resolution hemodynamic profiling of murine arteriovenous fistula using magnetic resonance imaging and computational fluid dynamics. Theor Biol Med Model. 14(1):5. PMCID: PMC5360029.
  • Qiu H, Novikov A, Vallon V. (2017) Ketosis and diabetic ketoacidosis in response to SGLT2 inhibitors: Basic mechanisms and therapeutic perspectives. Diabetes Metab Res Rev. [Epub ahead of print]
  • Redmann M, Benavides GA, Berryhill TF, Wani WY, Ouyang X, Johnson MS, Ravi S, Barnes S, Darley-Usmar VM, Zhang J. (2017) Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetics function in primary neurons. Redox Biol. 11:73-81. PMCID: PMC5124357.
  • Thomas JL, Pham H, Li Y, Hall E, Perkins GA, Ali SS, Patel HH, Singh P. (2017) Hypoxia inducible factor-1α activation improves renal oxygenation and mitochondrial function in early chronic kidney disease. Am J Physiol Renal Physiol. [Epub ahead of print].
  • Vallon V, Thomson SC. (2017) Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition. Diabetologia. 60(2):215-225. PMC Journal in Process
  • Yang L, Frindt G, Lang F, Kuhl D, Vallon V, Palmer LG. (2017) SGK1-dependent ENaC processing and trafficking in mice with high dietary K intake and elevated aldosterone. Am J Physiol Renal Physiol. 312(1):F65-F76. PMCID: PMC5283884.

Previous Publications


2016
  • Agarwal A, Dong Z, Harris R, Murray P, Parikh SM, Rosner MH, Kellum JA, Ronco C, Acute Dialysis Quality Initiative XIII Working Group. (2016) Cellular and Molecular Mechanisms of AKI. J Am Soc Nephrol. 27(5):1288-1299. PMCID: PMC4849836
  • Awidishu L, Joy MS. (2016) Role of Pharmacogenomics in Kidney Disease and Injury. Adv Chronic Kidney Dis. 23(2):106-119. Review.
  • Barnes S, Benton HP, Casazza K, Cooper SJ, Cui X, Du X, Engler J, Kabarowski JH, Li S, Pathmasiri W, Prasain JK, Renfrow MB, Tiwari HK. (2016) Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data. J Mass Spectrom. 51(7):461-475. PMCID: PMC4964969.
  • Barnes S, Benton HP, Casazza K, Cooper SJ, Cui X, Du X, Engler J, Kabarowski JH, Li S, Pathmasiri W, Prasain JK, Renfrow MB, Tiwari HK. (2016) Training in metabolomics research. II. Designing the experiment, collecting and extracting samples and generating metabolomics data. J Mass Spectrom. 51(8):535-548.
  • Bhatnagar V, Richard EL, Wu W, Nievergelt CM, Lipkowitz MS, Jeff J, Maihofer AX, Nigam SK. (2016) Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling. Clin Kidney. 9(3):444-453. PMCID: PMC4886906.
  • Bolisetty S, Traylor A, Joseph R, Zarjou A, Agarwal A. (2016) Proximal tubule-targeted heme oxygenase-1 in cisplatin-induced acute kidney injury. Am J Physiol Renal Physiol. 310(5):F385-F394. PMCID: PMC4868370.
  • Bouchard J, Mehta RL. (2016) Acute Kidney Injury in Western Countries. Kidney Dis (Basel). 2(3):103-110. PMCID: PMC5123002.
  • Chacko BK, Zhi D, Darley-Usmar VM, Mitchell T. (2016) The Bioenergetic Health Index is a sensitive measure of oxidative stress in human monocytes. Redox Biol. 8:43-50. PMCID: PMC4712317.
  • Curtis LM, Agarwal A. (2016) Heme Oxygenase-1 Gene Polymorphsims-Toward Precision Medicine for AKI. J Am Soc Nephrol. 27(11):3229-3231. PMCID: PMC5084904.
  • DeFreitas MJ, Seeherunvong W, Katsoufis CP, RamachandraRao S, Duara S, Yasin S, Zilleruelo G, Rodriguez MM, Abitbol CL. (2016) Longitudianl patterns of urine biomarkers in infnts across gestational ages. Pediatr Nephrol. 31(7):1179-1188.
  • Doshi M, Lahoti A, Danesh FR, Batuman V, Sanders PW, American Society of Nephrology Onco-Nephrology Forum. (2016) Paraprotein-Related Kidney Disease: Kidney Injury from Paraproteins-What Determines the Site of Injury? Clin J Am Soc Nephrol. 11(12):2288-2294. PMCID: PMC5142058.
  • Drummond CA, Crotty Alexander LE, Haller ST, Fan X, Xie JX, Kennedy DJ, Liu J, Yan Y, Hernandez DA, Mathew DP, Cooper CJ, Shapiro JI, Tian J. (2016) Cigarette smoking causes epigenetic changes associated with cardiorenal fibrosis. Physiol Genomics 48(12):950-960. PMCID: PMC5206391.
  • Gallo LA, Ward MS, Fotheringham AK, Zhuang A, Borg DJ, Flemming NB, Harvie BM, Kinneally TL, Yeh SM, McCarthy DA, Koepsell H, Vallon V, Pollock C, Panchapakesan U, Forbes JM. (2016) Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without imporving albuminuria in diabetic db/db mice. Sci Rep. 6:26428. PMCID: PMC4881020.
  • Heaven MR, Flint D, Randall SM, Sosunov AA, Wilson L, Barnes S, Goldman JE, Muddiman DC, Brenner M. (2016) Composition of Rosenthal Fibers, the protein aggregate Hallmark of Alesander Disease. J Proteome Res. 15(7):2265-2282. PMCID: PMC5036859.
  • Hull TD, Boddu R, Guo L, Tisher CC, Traylor AM, Patel B, Joseph R, Prabhu SD, Suliman HB, Piantadosi CA, Agarwal A, George JF. (2016) Heme osygenase-1 regulates mitochondrial quality control in the heart. JCI Insight. 1(2):e85817. PMCID: PMC4838906.
  • Inoue T, Abe C, Sung SS, Moscalu S, Jankowski J, Huang L, Ye H, Rosin DL, Guyenet PG, Okusa MD. (2016) Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+splenocytes. J Clin Invest.126(5):1939-1952. PMCID: PMC4855936.
  • Jackson JL, Judd SE, Panwar B, Howard VJ, Wadley VG, Jenny NS, Gutierrez OM. (2016) Associations of 25-hydroxyvitamin D with markers of inflammation, insulin resistance and obesity in black and white community-dwelling adults. J Clin Transl Endocrinol. 5:21-25. PMCID: PMC5098550.
  • Kefaloyianni E, Muthru ML, Kaeppler J, Sun X, Sabbisetti V, Chalaris A, Rose-John S, Wong E, Saqi I, Waikar SS, Rennke H, Humphreys BD, Bonventre JV, Herrlich A. (2016) ADAM 17 substrate release in proximal tubule drives kidney fibrosis. JCI Insight. 1(13):pii e87023. PMCID: PMC5026414.
  • Larson-Casey JL, Deshane JS, Ryan AJ, Thannickal VJ, Carter AB. (2016) Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis. Immunity. 44(3):582-596. PMCID: PMC4794358.
  • Layton AT, Laghmani K, Vallon V, Edwards A. (2016) Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors. Am J Physiol Renal Physiol. 311(6):F1217-F1229. PMCID: PMC5210208.
  • Layton AT, Vallon V, Edwards A. (2016) A computational model for simulating solute transport and oxygen consumption along the nephrons. Am J Physiol Renal Physiol. 311(6):F1378-F1390. PMCID: PMC5210192.
  • Leaf DE, Body SC, Muehlschlegel JD, McMahon GM, Lichtner P, Collard CD, Shernan SK, Fox AA, Waikar SS. (2016) Length Polymorphisms in Heme Oxygenase-1 and AKI after Cardiac Surgery. J Am Soc Nephrol. 27(11):3291-3297. PMCID: PMC5084897.
  • Leaf DE, Jacob KA, Srivastava A, Chen ME, Christov M, Juppner H, Sabbisetti VS, Martin A, Wolf M, Waikar SS. (2016) Fibroblast Growth Factor 23 Levels Associate with AKI and Death in Critical Illness. J Am Soc Nephrol. [Epub ahead of print]
  • Lebensburger JD, Palabindela P, Howard TH, Feig DI, Aban I, Askenazi DJ. (2016) Prevelance of acute kidney injury during pediatric admissions for acute chest syndrome. Pediatr Nephrol. 31(8):1363-1368. PMCID: PMC4920695.
  • Li X, Knight J, Fargue S, Buchalski B, Guan Z, Inscho EW, Liebow A, Fitzgerald K, Querbes W, Todd Lowther W, Holmes RP. (2016) Metabolism of (13) C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase. Biochim Biophys Acta. 1862(2):233-239. PMCID: PMC4706777.
  • Maarouf OH, Aravamudhan A, Rangarajan D, Kusaba T, Zhang V, Welborn J, Gaubin D, Hou X, Kramann R, Humphreys BD. (2016) Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk. J Am Soc Nephrol. 27(3):781-790. PMCID: PMC4769196.
  • Macedo E, Mehta RL. (2016) Renal Recovery after Acute Kidney Injury. Contrib Nephrol. 187:24-35. Review.
  • Mehta RL. (2016) Renal-Replacement Therapy in the Critically Ill—Does Timing Matter? N Engl J Med. 375(2):175-176. Commentary.
  • Mehta RL, Burdmann EA, Cerda J, Feehally J, Finkelstein F, Garcia-Garcia G, Godin M, Jha V, Lameire NH, Levin NW, Lewington A, Lombardi R, Macedo E, Rocco M, Aronoff-Spencer E, Tonelli M, Zhang J, Remuzzi G. (2016) Recognition and management of acute kidney injury in the International Society of Nephrology 0by25 Global Snapshot: a multinational cross-sectional study. Lancet. 387(10032):2017-2025.
  • Neprasova M, Maixnerova D, Novak J, Reily C, Julian BA, Boron J, Novotny P, Suchanek M, Tesar V, Kacer P. (2016) Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic Study. Dis Markers. 2016:3650909. PMCID: PMC5075301.
  • Novikov A, Vallon V. (2016) Sodium glucose cotransporter 2 inhibition in the diabetic kidney: an update. Curr Opin Nephrol Hypertens. 25(1):50-58. PMCID: PMC4703043.
  • Panwar B, Judd SE, Warnock DG, McClellan WM, Booth JN 3rd, Muntner P, Gutierrez OM. (2016) Hemoglobin Concentration and Risk of Incident Stroke in Community-Living Adults. Stroke. 47(8):2017-2024. PMCID: PMC4961542.
  • Pegues MA, McWilliams IL, Szalai AJ. (2016) C-reactive protein exacerbates renal ischemia-reperfusion injury: are myeloid-derived suppressor cells to blame? Am J Physiol Renal Physiol. 311(1):F176-F181. PMCID: PMC4967164.
  • Prasain JK, Rajbhandari R, Keeton AB, Piazza GA, Barnes S. (2016) Metabolism and growth inhibitory activity of cranberry derived flavonoids in bladder cancer cells. Food Funct. 7(9):4012-4019. PMCID: PMC5076555.
  • Rao S, Walters KB, Wilson L, Chen B, Bolisetty S, Graves D. Barnes S, Agarwal A, Kabarowski JH. (2016) Early lipid changes in acute kidney injury using SWATH lipidomics couples with MALDI tissue imaging. Am J Physiol Renal Physiol. 310(10):F1136-F1147. PMCID: PMC4889318.
  • Ravi S, Johnson MS, Chacko BK, Kramer PA, Sawada H, Locy ML, Wilson LS, Barnes S, Marques MB, Darley-Usmar VM. (2016) Modification of platelet proteins by 4-hydroxynonenal: Potential Mechanisms for inhibition of aggregation and metabolism. Free Radic Biol Med.91:143-153. PMCID: PMC4761519.
  • Smith MR, Vayalil PK, Zhou F, Benavides GA, Beggs RR, Golzarian H, Nijampatnam B, Oliver PG, Smith RA, Murphy MP, Velu SE, Landar A. (2016) Mitochondrial thiol modification by targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels. Redox Biol. 8:136-148. PMCID: PMC4732023.
  • Song P, Onishi A, Koepsell H, Vallon V. (2016) Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus. Expert Opin Ther Targets. 20(9):1109-1125. PMCID: PMC5045806.
  • Tamhane AR, Westfall AO, Burkholder GA, Cutter GR. (2016) Prevalence odds ratio versus prevalence ration: choice comes with consequences. Stat Med. 35(30):5730-5735. PMCID: PMC5135596.
  • Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP, Parikh SM. (2016) PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection. Nature. 531(7595):528-532. PMCID: PMC4909121.
  • Vallon V. (2016) Tubular Transport in Acute Kidney Injury: Relevance for Diagnosis, Prognosis and Intervention. Nephron. 134(3):160-166. PMCID: PMC5089910.
  • Walker VJ, Agarwal A. (2016) Targeting Iron Homeostasis in Acute Kidney Injury. Semin Nephrol. 36(1):62-70. Review. PMCID: PMC5439503
  • Warnock DG, Powell TC, Siew ED, Donnelly JP, Wang HE, Mehta RL. (2016) Serum Creatinine Trajectories for Community-versus Hospital-Acquired Acute Kidney Injury. Nephron. 134(3):177-182. Review.
  • Weir MR, Blantz RC. (2016) Noteworthy observation in hypertension from 2015. Curr Opin Nephrol Hypertens. 25(1):1-2. Review.
  • Williams J, Homes RP, Assimos DG, Mitchell T. (2016) Monocyte Mitochondrial Function in Calcium Oxalate Stone Formers. Urology 93:224.e1-224.e6. PMCID: PMC4914421.
2015

  • Askenazi DJ, Halloran B, Patil N, Keeling S, Saeidi B, Koralkar R, Ambalavanan N. (2015) Genetic polymorphisms of heme-oxygenase 1 (HO-1) may impact on acute kidney injury, bronchopulmonary dysplasia, and mortality in premature infants. Pediatr Res. 77(6):793-798. PMCID: PMC4439308.
  • Bajwa A, Rosin DK, Chroscicki P, Lee S, Dondeti K, Ye H, Kinsey GR, Stevens BK, Jobin K, Kenwood BM, Hoehn KL, Lynch KR, Okusa MD. (2015) Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury. J Am Soc Nephrol. 26(4):908-925. PMCID: PMC4378101.
  • Black LL, Srivastava R, Schoeb TR, Moore RD, Barnes S, Kabarowski JH. (2015) Cholesterol-Independent Supression of Lymphocyte Activation, Autoimmunity, and Glomerulonephritis by Apolipoprotein A-I in Normocholesterolemic Lupus-Prone Mice. J Immunol. 195(10):4685-4698. PMCID: PMC4637240.
  • Blantz RC, Steiner RW. (2015) Benign hyperfiltration after living kidney donation. J Clin Invest. 125(3):972-974. PMCID PMC4362244.
  • Boddu R, Hull TD, Bolisetty S, Hu X, Moehle MS, Daher JP, Kamal AI, Joseph R, George JF, Agarwal A, Curtis LM, West AB. (2015) Leucine-rich repeat kinase 2 deficiency is protective in rhabdomolysis-induced kidney injury. Hum Mol Genet. 24(14):4078-4093. PMCID: PMC4476452.
  • Bolisetty S, Zarjou A, Hull TD, Traylor AM, Perianayagam A, Joseph R, Kamal AI, Arosio P, Soares MP, Jeney V, Balla J, George JF, Agarwal A. (2015) Macrophage and epithelial cell H-ferritin expression regulates renal inflammation. Kidney Int. 88(1):95-108. PMCID: PMC4490000.
  • Bouchard J, Acharya A, Cerda J, Maccariello ER, Madarasu RC, Tolwani AJ, Liang X, Fu P, Liu ZH, Mehta RL. (2015) A Prospective International Multicenter Study of AKI in the Intensive Care Unit. Clin J Am Soc Nephrol. 10(8):1324-1331. PMCID: PMC4527019.
  • Brossier NM, Prechtl AM, Longo JF, Barnes S, Wilson LS, Byer SJ, Brosius SN, Carroll SL. (2015) Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells. J Neuropathol Exp Neurol. 74(6):568-586. PMCID: PMC4433624.
  • Conway KS, Forbang N, Beben T, Criqui MH, Ix JH, Rifkin DE. (2015) Relationship Between 24-Hour Ambulatory Blood Pressure and Cognitive Function in Community-Living Older Adults: The UCSD Ambulatory Blood Pressure Study. Am J Hypertens. 28(12):1444-1452. PMCID: PMC4654763.
  • Dominguez Rieg JA, Burt JM, Ruth P, Rieg T. (2015) P2Y2 receptor activation decreases blood pressure via intermediate conductance potassium channels and connexin 37. Acta Physio (Oxf) 213(3):628-641. PMCID PMC4442688.
  • Feng W, Chumley P, Prieto MC, Miyada K, Seth DM, Fatima H, Hua P, Rezonzew G, Sanders PW, Jaimes EA. (2015) Transcription factor avian erythroblastosis virus E26 oncogen homolog-1 is a novel mediator of renal injury in salt-sensitive hypertension. Hypertension. 65(4):813-820. PMCID: PMC4897962.
  • Feng W, Ying WZ, Aaron KJ, Sanders PW. (2015) Transforming growth factor-β mediates endothelial dysfunction in rats during high salt intake. Am J Physiol Renal Physiol. 309(12):F1018-F1025. PMCID: PMC4683308.
  • Fenton RA, Poulsen SB, de la Mora Chavez S, Soleimani M, Busslinger M, Dominguez Rieg JA, Rieg T. (2015) Caffeine-induced diuresis and natriuresis is independent of rental tubular NHE3. Am J Physiol Renal Physiol. 308(12):F1409-F1420. PMCID: PMC4587593.
  • Fu Y, Gerasimova M, Batz F, Kuczkowski A, Alam Y, Sander PW, Ronzaud C, Hummler E, Vallon V. (2015) PPARγ agonist-induced fluid retention depends on αENaC expression in connecting tubules. Nephron. 129(1):68-74. PMCID: PMC4323851.
  • Gallo LA, Wright EM, Vallon V. (2015) Probing SGLT2 as a therapeutic target for diabetes: basic physiology and consequences. Diab Vasc Dis Res. 12(2):78-89. Review.
  • Girkin CA, Nievergelt CM, Kuo JZ, Maihofer AX, Huisingh C, Liebmann JM, Ayyagari R, Weinreb RN, Ritch R, Zangwill LM, ADAGES Study Group. (2015) Biogeographic Ancestry in the African Descent and Glaucoma Evaluation Study (ADAGES): Association With Corneal and Optic Nerve Structure. Invest Ophthalmol Vis Sci. 56(3):2043-2049. PMCID: PMC4373542.
  • Godin M, Murray P, Mehta RL. (2015) Clinical approach to the patient with AKI and sepsis. Semin Nephrol. 35(1):12-22. Review.
  • Hanks LJ, Casazza K, Ashraf AP, Wallace S, Gutierrez OM. (2015) Fibroblast growth factor-21 body composition, and insulin resistance in pre-pubertal and early pubertal males and females. Clin Endocrinol (Oxf). 82(4):550-556. PMCID: PMC4289452.
  • Hanks LJ, Gutierrez OM, Ashraf AP, Casazza K. (2015) Bone Mineral Content as a Driver of Energy Expenditure in Prepubertal and Early Pubertal Boys. J Pediatr. 166(6):1397-1403. PMCID: PMC4446221.
  • Hanks LJ, Gutierrez OM, Bamman MM, Ashraf A, McCormick KL, Casazza K. (2015) Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals. J Clin Transl Endocrinol. 2(2):77-82. PMCID: PMC4450097.
  • Harper VM, Oh JY, Stapley R, Marques MB, Wilson L, Barnes S, Sun CW, Townes T, Patel RP. (2015) Peroxiredoxin-2 recycling is inhibited during erythrocyte storage. Antioxid Redox Signal. 22(4):294-307. PMCID: PMC4298151.
  • Hoyt K, Warram JM, Wang D, Ratnayaka S, Traylor A, Agarwal A. (2015) Molecular Ultrasound Imaging of Tissue Inflammation Using an Animal Model of Acute Kidney Injury. Mol Imaging Biol. 17(6):786-792. PMCID: PMC4818575.
  • Hull TD, Kamal AI, Boddu R, Bolisetty S, Guo L, Tisher CC, Rangarajan S, Chen B, Curtis LM, George JF, Agarwal A. (2015) Heme Oxygenase-1 Regulates Myeloid Cell Trafficking in AKI. J Am Soc Nephrol. 26(9):2139-2151. PMCID: PMC4552119.
  • Jansone B, Kadish I, van Groen T, Beitnere U, Moore DR, Plotneice A, Pajuste K, Klusa V. (2015) A Novel 1,4-Dihydrophridine Derivative Improves Spatial Learning and Memory and Modifies Brain Protein Expression in Wild Type and Transgenic APPSweDI Mice. PLoS One. 10(6):e0127686. PMCID: PMC4456351.
  • Kramann R, Fleig SV, Schneider RK, Fabian SL, DiRocco DP, Maarouf O, Wongboonsin J, Ikeda Y, Heckl D, Chang SL, Rennke HG, Waikar SS, Humphreys BD. (2015) {harmacological GLI2 inhibition prevents myfibroblast cell-cycle progression and reduced kidney fibrosis. J Clin Invest. 125(8):2935-2951. PMCID: PMC4563736.
  • Kramer PA, Chacko BK, George DJ, Zhi D, Wei CC, Dell’Italia LJ, Melby SJ, George JF, Darley-Usmar VM. (2015) Decreased Bioenergetic Health Index in monocytes isolated from the pericardial fluid and blood of postoperative cardiac surgery patients. Biosci Rep. 35(4):e00237. PMCID: PMC4613711.
  • Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Barnes S, Arabshahi A, Dell’Italia LJ, George DJ, Steele C, George JF, Darley-Usmar VM, Melby SJ. (2015) Hemoglobin-associated oxidative stress in the pericardial compartment of postoperative cardiac surgery. Lab Invest. 95(2):132-141. PMCID: PMC4422823.
  • Kramer PA, Darley-Usmar VM. (2015) The emerging theme of redoc bioenergetics in health and disease. Biomed J. 38(4):294-300. Review.
  • Kramer PA, Prichard L, Chacko B, Ravi S, Overton ET, Heath SL, Darley-Usmar V. (2015) Inhibition of the lymphocyte metabolic switch by the oxidative burst of human neutrophils. Clin Sci (Lond.) 129(6):489-504.
  • Layton AT, Vallon V, Edwards A. (2015) Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition. Am J Physiol Renal Physiol. 308(12):F1343-F1357. PMCID: PMC4469883.
  • Lebensburger JD, Hilliard LM, Pair LE, Oster R, Howard TH, Cutter GR. (2015) Systematic review of interventional sickle cell trails registered in ClinicalTrials.gov. Clin Trials. 12(6):575-583. PMCID: PMC4643416.
  • Li H, Satriano J, Thomas JL, Miyamoto S, Sharma K, Pastor-Soler NM, Hallows KR, Singh P. (2015) Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease. Am J Physiol Renal Physiol. 309(5):F414-F428. PMCID: PMC4556888.
  • Lopez EF, Kabarowski JH, Ingle KA, Kain V, Barnes S, Crossman DK, Lindsey ML, Halade GV. (2015) Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction. Am J Physiol Heart Circ Physiol. 308(4):H269-H280. PMCID: PMC4329482.
  • Michel MC, Mayoux E, Vallon V. (2015) A comprehensive review of the pharmacodynamics of the SGLT2 inhibitor empagliflozin in animals and humans. Naunyn Schmiedebergs Arch Pharmacol. 388(3):801-816. Review.
  • Minassian A, Maihofer AX, Baker DG, Nievergelt CM, Geyer MA, Risbrough VB, Marine Resiliency Study Team. (2015) Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines. JAMA Psychiatry. 72(10):979-986.
  • Mrug M, Zhou J, Yang C, Aronow BJ, Cui X, Schoeb TR, Siegal GP, Yoder BK, Guay-Woodford LM. (2015) Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse. PLoS One.10(8):e0135678. PMCID: PMC4546649.
  • Murthy S, Larson-Casey JL, Ryan AJ, He C, Kobzik L, Carter AB. (2015) Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, macrophage receptor with collagenous structure. FASEB J. 29(8):3527-3536. PMCID: PMC4511206.
  • Pang P, Jin X, Proctor BM, Farley M, Roy N, Chin MS, von Andrian UH, Vollmann E, Perro M, Hoffman RJ, Chung J, Chauhan N, Mistri M, Muslin AJ, Bonventre JV, Siedlecki AM. (2015) RGS4 inhibits angiotensis II signaling and macrophage localization during renal reperfusion injury independent of vasospasm. Kidney Int. 87(4):771-783. PMCID: PMC4382433.
  • Powell TC, Warnock DG. (2015) The Furosemide Stress Test and Predicting AKI Outcomes. J Am Soc Nephrol. 26(8):1762-1764. PMCID: PMC4520179.
  • Prasain JK, Wilson L, Hoang HD, Moore R, Miller MA. (2015) Comparative Lipidomics of Caenorhabditis elegans Metabolic Disease Models by SWATH Non-Targeted Tandem Mass Spectrometry. Metabolites. 5(4):677-696. PMCID: PMC4693190.
  • RamachandraRao SP, Matthias MA, Kokoy-Mondragon C, Aghania E, Park C, Kong C, Ishaya M, Madrigal A, Horng J, Khoshaba R, Bounkhoun A, Basilico F, De Palma A, Agresta AM, Awdishu L, Naviaux RK, Vinetz JM, Mauri P. (2015) Correction: Proteomic analysis of urine exosomes reveals renal tubule response to leptospiral colonization in experimentally infected rats. PLoS Negl Trop Dis. 9(4):e0003718. PMCID: PMC4393270.
  • RamachandraRao SP, Matthias MA, Mondrogon CK, Aghania E, Park C, Kong C, Ishaya M, Madrigal A, Horng J, Khoshaba R, Bounkhoun A, Basilico F, De Palma A, Agresta AM, Awidishu L, Naviaux RK, Vinetz JM, Mauri P. (2015) Proteomic analysis of urine exposomes reveals renal tubule response to leptospiral colonization in experimentally infected rats. PLoS Negl Trop Dis. 9(3):e0003640. PMCID: PMC4368819.
  • Rao F, Schork AJ, Maihofer AX, Nievergelt CM, Marcovina SM, Miller ER, Witztum JL, O’Connor DT, Tsimikas S. (2015) Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study. Arterioscler Thromb Vasc Biol. 35(7):1704-1711. PMCID: PMC4483152.
  • Ravi S, Chacko B, Kramer PA, Sawada H, Johnson MS, Zhi D, Marques MB, Darley-Usmar VM. (2015) Defining the effects of storage on platelet bioenergetics: The role of increased proton leak. Biochim Biophys Acta. 1852(11):2525-2534. PMCID: PMC4582014.
  • Saeidi B, Koralkar R, Griffin RL, Halloran B, Ambalavanan N, Askenazi DJ. (2015) Impact of gestational age, sex and postnatal age on urine biomarkers in premature neonates. Pediatr Nephrol. 30(11):2037-2044. PMCID: PMC4581905.
  • Singh SP, Tao S, Fields TA, Webb S, Harris RC, Rao R. (2015) Glycogen synthase kinase-3 inhibition attenuates fibroblast activation and development of fibrosis following renal ischemia-reperfusion in mice. Dis Model Mech. 8(8):931-940. PMCID: PMC4527294.
  • Speed JS, Fox BM, Johnston JG, Pollock DM. (2015) Endothelin and renal ion and water transport. Semin Nephrol. 35(2):137-144. PMCID: PMC4499165.
  • Speed JS, Heimlich JB, Hyndman KA, Fox BM, Patel V, Yanagisawa M, Pollock JS, Titze JM, Pollock DM. (2015) Endothelin-1 as a master regulator of whole-body NA+ homeostasis. FASEB J. 29(12):4937-4944. PMCID: PMC4653060.
  • Speed JS, Pollock DM. (2015) New clues towards solving the mystery of endothelin and blood pressure regulation. Hypertension. 66(2):275-277. PMCID: PMC4498997.
  • Surolia R, Karki S, Kim H, Yu Z, Kulkarni T, Mirov SB, Carter AB, Rowe SM, Matalon S, Thannickal VJ, Agarwal A, Antony VB. (2015) Heme oxyganse-1-mediated autophagy protects against pulmonary endothelial cell death and development of emphysema in cadmium-treated mice. Am J Physiol Lung Cell Mol Physiol. 309(3):L280-L292. PMCID: PMC4525122.
  • Vallon V. (2015) The mechanisms and therapeutic potential of SGLT2 inhibitors in diabetes mellitus. Annu Rev Med. 66:255-270. Review.
  • Wall SB, Oh JY, Mitchell L, Laube AH, Campbell SL, Renfrow MB, Landar A. (2015) Rac1 modification by an electrophilic 15-deoxy delta(12,14)-prostaglandin J2 analog. Redox Biol. 4:346-354. PMCID: PMC4326178.
  • Warnock DG, Powell TC, Donnelly JP, Wang HE. (2015) Categories of Hospital-Associated Acute Kidney Injury: Time Course of Changes in Serum Creatinine Values. Nephron. 131(4):227-236. PMCID: PMC4698143.
  • Wells JM, Jackson PL, Viera L, Bhatt SP, Gautney J, Handley G, King RW, Xu X, Gaggar A, Bailey WC, Dransfield MT, Blalock JE. (2015) A randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Gylcine-Proline and neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 192(8):934-942. PMCID: PMC4642210.
  • Yadav P, Leung N, Sanders PW, Cockwell P. (2015) the use of immunoglobulin light chain assays in the diagnosis of paraprotein-related kidney disease. Kidney Int. 87(4):692-697. PMCID: PMC4863638.
  • Zhang K, Mir SA, Hightower CM, Miramontes-Gonzalez JP, Maihofer AX, Chen Y, Mahata SK, Nievergelt CM, Schork NJ, Freedman BI, Vaingankar SM, O’Connor DT. (2015) Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3’-Untranslated Region Polymorphism C+87T by MicroRNA-107. J Am Soc Nephrol. 26(8):1816-1825. PMCID: PMC4520173.
2014

  • Abdul Roda M, Sadik M, Gaggar A, Hardison MT, Jablonsky MJ, Braber S, Blalock JE, Redegeld FA, Folkerts G, Jackson PL. (2014) Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation. PLoS One. 9(5):e97594. PMCID: PMC4023971.
  • Andringa KK, Agarwal A. (2014) Role of hypoxia-inducible factors in acute kidney injury. Nephron Clin Pract. 127(1-4):70-74. Review.
  • Askenazi DJ, Moore JF, Fineberg N, Koralkar R, Clevenger S, Sharer JD. (2014) Comparison of methods, storage conditions, and time to analysis of serum and urine creatinine measured from microsamples by liquid chromatography mass spectrometry (LC/MS) vs. Jaffe. J Clin Lab Anal. 28(5):405-408. Comparison Study.
  • Billings FT 4th, Shaw AD. (2014) Clinical trial endpoints in acute kidney injury. Nephron Clin Pract. 127(1-4):89-93. PMCID: PMC4480222.
  • Blantz RC. (2014) Phenotypic characteristics of diabetic kidney involvement. Kidney Int. 86(1):7-9. PMCID: PMC4076684.
  • Blantz RC, Singh P. (2014) Glomerular and tubular function in the diabetic kiney. Adv Chronic Kidney Dis. 21(3):297-303. Review.
  • Borsting E, Cheng VP, Glass CK, Vallon V, Cunard R. (2012) Peroxisome proliferator-activated receptor-γ agonists repress epithelial sodium channel expression in the kidney. Am J Physiol Renal Physiol. 302(5):F540-F551. PMCID: PMC3353644.
  • Borsting E, Patel SV, Decleves AE, Lee SJ, Rahman QM, Akira S, Satriano J, Sharma K, Vallon V, Cunard R. (2014) Tribbles Homolog 3 Attenuates Mammalian Target of Rapamycin Complex-2 Signaling and Inflammation in the Diabetic Kidney. J Am Soc Nephrol. 25(9):2067-2078. PMCID: PMC4147976.
  • Bowling CB, Muntner P, Sawyer P, Sanders PW, Kutner N, Kennedy R, Allman RM. (2014) Community mobility among older adults with reduced kidney function: a study of life-space. Am J Kidney Dis. 63(3):429-436. PMCID: PMC3943884.
  • Chacko BK, Kramer PA, Ravi S, Benavides GA, Mitchell T, Dranka BP, Ferrick D, Singal AK, Ballinger SW, Bailey SM, Hardy RW, Zhang J, Zhi D, Darley-Usmar VM. (2014) The Bioenergetic Health Index: a new concept in mitochondrial translational research. Clin Sci (Lond). 127(6):367-373. PMCID: PMC4202728.
  • Claure-Del Granado R, Macedo E, Soroko S, Kim Y, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. (2014) Anticoagulation, delivered dose and outcomes in CRRT: The program to improve care in acute renal disease (PICARD). Hemodial Int. 18(3):641-649. PMCID: PMC4220040.
  • Decleves AE, Sharma K, Satriano J. (2014) Beneficial Effects of AMP-Activated Protein Kinase Agonists in Kidney Ischemia-Reperfusion: Autophagy and Cellular Stress Markers. Nephron Exp Nephrol. PMCID: PMC4458239.
  • Edwards A, Castrop H, Laghmani K, Vallon V, Layton AT. (2014) Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study. Am J Physiol Renal Physiol. 307(2):F137-F146. PMCID: PMC4101627.
  • Feng W, Chumley P, Allon M, George J, Scott DW, Patel RP, Litovsky S, Jaimes EA. (2014) The transcription factor E26 transformation-specific sequence-1 mediates neointima formation in arteriovenous fistula. J Am Soc Nephrol. 25(3):475-87. PMCID: PMC3935588.
  • Fenton RA, Murray F, Dominguez Rieg JA, Tang T, Levi M, Rieg T. (2014) Renal Phosphate Wasting in the Absence of Adenylyl Cyclase 6. J Am Soc Nephrol. 25(12):2822-2834. PMCID: PMC4243352.
  • Fu Y, Vallon V. (2014) Mineralcorticoid-induced sodium appetite and renal salt rentention: evidence for sommon signaling and effector mechanisms. Nephron Physiol. 128(1-2):8-16. PMCID: PMC4275376.
  • Gorboulev V, Schurmann A, Vallon V, Kipp H, Jaschke A, Klessen D, Friedrich A, Scherneck S, Rieg T, Cunard R, Veyhl-Wichmann M, Srinivasan A, Balen D, Breljak D, Rexhepaj R, Parker HE, Gribble FM, Reimann F, Lang F, Wiese S, Sabolic I, Sendtner M, Koepsell H. (2012) Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes. 61(1):187-196. PMCID: PMC3237647.
  • Hovater MB, Ying WZ, Agarwal A, Sanders PW. (2014) Nitric oxide and carbon monoxide antagonize TGF-β through ligand-independent internalization of TβR1/ALK5. Am J Physiol Renal Physiol. 307(6):F727-F735. PMCID: PMC4166728.
  • Hull TD, Agarwal A. (2014) Bilirubin: a potential biomarker and therapeutic target for diabetic nephropathy. Diabetes. 63(8):2613-2616. PMCID: PMC4113062.
  • Hull TD, Agarwal A, George JF. (2014) The mononuclear phagocyte system in homeostasis and disease: a role for heme oxygenase-1. Antioxid Redox Signal. 20(11):1770-1788. PMCID: PMC3961794.
  • Inampudi C, Parvataneni S, Morgan CJ, Deedwania P, Fonarow GC, Sanders PW, Prabhu SD, Butler J, Forman DE, Aronow WS, Allman RM, Ahmed A. (2014) Spironolactone use and higher hospital readmission for Medicare beneficiaries with heart failure, left ventricular ejection fraction <45%, and estimated glomerular filtration rate <45 ml/min/1.73 m(2.). Am J Caridol. 114(1):79-82. PMCID: PMC4169696.
  • Judd EK, Calhoun DA, Warnock DG. (2014) Pathophysiology and treatment of resistant hypertension: the role of aldosterone and amiloride-sensitive sodium channels. Semin Nephrol. 34(5):532-539. PMCID: PMC4450367.
  • Kasimsetty SG, DeWolf SE, Shigeoka AA, McKay DB. (2014) Regulation of TLR2 and NLRP3 in primary murine renal tubular epithelial cells. Nephron Clin Pract. 127(1-4):119-123. PMCID: PMC4896108.
  • Khan SQ, Guo L, Cimbaluk DJ, Elshabrawy H, Garidi MH, Jolly M, George JF, Agarwal A, Gupta V. (2014) A Small Molecule β2 Integrin Agonist Improves Chronic Kidney Allograft Survival by Reducing Leukocyte Recruitment and Accompanying Vasculopathy. Front Med (Lausanne) 1:45. PMCID: PMC4291902.
  • Kim T, He L, Johnson MS, Li Y, Zeng L, Ding Y, Long Q, Moore JF, Sharer JD, Nagy TR, Young ME, Wood PA, Yang Q. (2014) Carnitine Palmitoyltransferase 1b Deficiency Protects Mice from Diet-Induced Insulin Resistance. J Diabetes Metab. 5(4):361. PMCID: PMC4190034.
  • Kim T, Moore JF, Sharer JD, Yang K, Wood PA, Yang Q. (2014) Carnitine Palmitoyltransferase 1b Deficient Mice Develop Severe Insulin Resistance After Prolonged High Fat Diet Feeding. J Diabetes Metab. 5:pii1000401. PMCID: PMC4286342.
  • Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Darley-Usmar VM. (2014) Bioenergetics and the oxidative burst: protocols for the isolation and evaluation of human leukocytes and platelets. J Vis Exp. (85). PMCID: PMC4089433.
  • Kramer PA, Ravi S, Chacko B, Johnson MS, Darley-Usmar VM. (2014) A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: Implication for their use as bioenergetics biomarkers. Redox Biol. 2:206-210. PMCID: PMC3909784.
  • Kumar R, Vallon V. (2014) Reduced renal calcium excretion in the absence of sclerostin expression: evidence for a novel calcium-regulating bone kidney axis. J Am Soc Nephrol. 25(10):2159-2168. PMCID: PMC4178449.
  • Mahoney M, Sorace A, Warram J Samuel S, Hoyt K. (2014) Volumetric contrast-enhanced ultrasound imaging of renal perfusion. J Ultrasound Med. 33(8):1427-1437. PMCID: PMC4135386.
  • Masuda T, Fu Y, Equchi A, Czogalla J, Rose MA, Kuczkowski A, Gerasimova M, Feldstein AE, Scadeng M, Vallon V. (2014) Dipeptidyl peptidase IV inhibitor lowers PPARγ agonist-induced body weight gain by affecting food intake, fat mass, and beige/brown fat but not fluid retention. Am J Physiol Endocrinol Metab. 306(4):E388-E398. PMCID: PMC3923087.
  • McKnight K, Hoang HD, Prasain JK, Brown N, Vibbert J, Hollister KA, Moore R, Ragains JR, Reese J, Miller MA. (2014) Neurosensory perception of environmental cues modulates sperm motility critical for fertilization. Science. 344(6185):754-757. PMCID: PMC4094289.
  • Mehta RL, Kellum JA. (2014) Targeting recovery from acute kidney injury: executive summary from the round table conference at the 19th International Conference on Continuous Renal Replacement Therapies (Manchester Grand Hyatt, San Diego, Calif., USA, March 2-3 2014). Nephron Clin Pract. 127(1-4):1-3. PMCID: PMC4220039.
  • Mehta RL, Sanders PW, Agarwal A. (2014) Changing paradigms in acute kidney injury: from mechanisms to management – proceedings of the 5th annual UAB-UCSD O’Brien Center Symposiu (San Diego, Calif., USA, March 4, 2014). Nephron Clin Pract. 127(1-4):117-118. PMCID: PMC4309370.
  • Murray PT, Mehta RL, Shaw A, Ronco C, Endre Z, Kellum JA, Chawla LS, Cruz D, Ince C, Okusa MD, ADQI 10 Workgroup. (2014) Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative Consensus Conference. Kidney Int. 85(3):513-521. PMCID: PMC4198530.
  • Nourbakhsh N, Singh P. (2014) Role of renal oxygenation and mitochondrial function in the pathophysiology of acute kidney injury. Nephron Clin Pract. 127(1-4):149-152. Review.
  • Portilla D. (2014) Apoptosis, fibrosis and senescence. Nephron Clin Pract. 127(1-4):65-69. Review.
  • Rangarajan S, Sunil B, Fan C, Wang PX, Cutter G, Sanders PW, Curtis LM. (2014) Distinct populations of label-retaining cells in the adult kidney are defined temporally and exhibit divergent regional distributions. Am J Physiol Renal Physiol. 307(11):F1274-F1282. PMCID: PMC4254969.
  • Ravi S, Mitchell T, Kramer PA, Chacko B, Darley-Usmar VM. (2014) Mitochondria in monocytes and macrophages-implications for translational and basic research. Int J Biochem Cell Biol. 53C:202-207. PMCID: PMC4111987.
  • Reily C, Ueda H, Huang ZQ, Mestecky J, Julian BA, Willey CD, Novak J. (2014) Cellular signaling and production of glalctose-deficiant IgA1 in IgA nephropathy, an autoimmune disease. J Immunol Res. 2014:197548. PMCID: PMC4134797.
  • Rieg T, Kohan DE. (2014) Regulation of nephron water and electrolyte transport by adenylyl cyclases. Am J Physiol Renal Physiol. 306(7):F701-F709. PMCID: PMC3962601.
  • Rieg T, Masuda T, Gerasimova M, Mayoux E, Platt K, Powell DR, Thomson SC, Koepsell H, Vallon V. (2014) Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia. Am J Physiol Renal Physiol. 306(2):F188-F193. PMCID: PMC3920019
  • Singh P, Thomson SC. (2014) Salt sensitivity of tubuloglomerular feedback in the early remnant kidney.Am J Physiol Renal Physiol. 306(2):F172-F180. PMCID: PMC3920016.
  • Vallon V. (2014) Do tubular changes in the diabetic kidney affect the susceptibility to acute kidney injury? Nephron Clin Pract. 127(1-4):133-138. Review.
  • Vallon V, Docherty NG. (2014) Intestinal regulation of urinary sodium excretion and the pathophysiology of diabetic kidney disease: a focus on glucagon-like peptide 1 and dipeptidyl peptidase 4. Exp Physiol. 99(9):1140-1145. PMCID: PMC4162767.
  • Vallon V, Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, Koepsell H, Thomson SC, Rieg T. (2014) SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. Am J Physiol Renal Physiol. 306(2):F194-F204. PMCID: PMC3920018.
  • Virk-Baker MK, Barnes S, Krontiras H, Nagy TR. (2014) S-(-) equol producing status not associated with breast cancer risk among low isoflavone-consuming US postmenopausal women undergroing a physician-recommended breast biopsy. Nutr Res. 34(2):116-125. PMCID: PMC4028846.
  • Wall SB, Smith MR, Ricart K, Zhou F, Vayalil PK, Oh JY, Landar A. (2014) Detection of electrophile-sensitivie proteins. Biochim Biophys Acta. 1840(2):913-922. PMCID: PMC3858512.
  • Warnock DG, Kusche-Vihrog K, Tarjus A, Sheng S, Oberleithner H, Kleyman TR, Jaisser F. (2014) Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells. Nat Rev Nephrol. 10(3):146-157. PMCID: PMC4137491.
  • Wetta LA, Biggio JR, Cliver S, Abramovici A, Barnes S, Tita AT. (2014) Is midtrimester vitamin D status associated with spontaneous preterm birth and preeclampsia? Am J Perinatol. 31(6):541-546. PMCID: PMC4451220.
  • Wells JM, O’Reilly PJ, Szul T, Sullivan DI, Handley G, Garrett C, McNicholas CM, Roda MA, Miller BE, Tal-Singer R, Gaggar A, Rennard SI, Jackson PL, Blalock JE. (2014) An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 190(1):51-61. PMCID: PMC4226028.
  • Wilson L, Arabshahi A, Simons B, Prasain J, Barnes S. (2014) Improved high sensitivity analysis of polyphenols and their metabolites by nano-liquid chromatography-mass spectrometry. Arch Biochem Biophys. 559:3-11. PMCID: PMC4143533.
  • Ying WZ, Aaron KJ, Sanders PW. (2014) Sodium and potassium regulate endothelial phospholipase C-γ and Bmx. Am J Physiol Renal Physiol. 307(1):F58-F63. PMCID: PMC4080160.
2013

  • Aaron KJ, Sanders PW. (2013) Role of dietary salt and potassium intake in cardiovascular health and disease: a review of the evidence. Mayo Clin Proc. 88(9):987-995. PMCID: PMC3833247.
  • Allen CE, Sanders PW. (2013) Hypertensive nephrosclerosis: not enough of a good thing? Am J Physiol Renal Physiol. 304(6):F674-F675. PMCID: PMC3602697.
  • Askenazi DJ, Koralkar R, Hundley HE, Montesanti A, Patil N, Ambalavanan N. (2013) Fluid overload and mortality are associated with acute kidney injury in sick near-term/term neonate. Pediatr Nephrol. 28(4):661-666. Non-government funded study.
  • Askenazi DJ, Goldstein SL, Koralkar R, Fortenberry J, Baum M, Hackbarth R, Blowey D, Bunchman TE, Brophy PD, Symons J, Chua A, Flores F, Somers MJ. (2013) Continuous renal replacement therapy for children ≤ 10kg: a report from the prospective pediatric continuous renal replacement therapy registry. J Pediatr. 162(3):587-592.
  • Barnes S, Prasain J, Kim H. (2013) In nutrition, can we “see” what is good for us? Adv Nutr. 4(3):327S-334S. PMCID: PMC3650504.
  • Bhanushali GK, Jain G, Fatima H, Leisch LJ, Thornley-Brown D. (2013) AKI associated with synthetic cannabinoids: a case series. Clin J Am Soc Nephrol. 8(4):523-526. PMCID: PMC3613952.
  • Bolisetty S, Traylor A, Zarjou A, Johnson MS, Benavides GA, Ricart K, Boddu R, Moore RD, Landar A, Barnes S, Darley-Usmar V, Agarwal A. (2013) Mitochondria-targeted heme oxygenase-1 decreases oxidative stress in renal epithelial cells. Am J Physiol Renal Physiol. 305(3):F255-F264. PMCID: PMC3742869.
  • Bowling CB, Sanders PW, Allman RM, Rogers WJ, Patel K, Aban IB, Rich MW, Pitt B, White M, Bakris GC, Fonarow GC, Ahmed A. (2013) Effects of enalapril in systolic heart failure patients with and without chronic kidney disease: insights from the SOLVD treatment trial. Int J Cardiol. 167(1):151-156. PMCID: PMC3395757.
  • Chacko BK, Kramer PA, Ravi S, Johnson MS, Hardy RW, Ballinger SW, Darley-Usmar VM. (2013) Methods for defining distinct bioenergetics profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood. Lab Invest. 93(6):690-700. PMCID: PMC3674307.
  • Clement LC*, Macé C*, Avila-Casado C, Joles JA, Kersten S, Chugh SS. (2013) Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. Nat Med. 20(1):37-46. PMCID: PMC4114723.
  • Cowley AW Jr, Ryan RP, Kurth T, Skelton MM, Schock-Kursch D, Gretz N. (2013) Progression of glomerular filtration rate reduction determined in conscious Dahl salt-sensitive hypertensive rats. Hypertension. 62(1):85-90. PMCID: PMC3806646.
  • DuPont JJ, Greaney JL, Wenner MM, Lennon-Edwards SL, Sanders PW, Farquhar WB, Edwards DG. (2013) High dietary sodium intake impairs endothelium-dependent dilation in healthy salt-resistant humans. J Hypertens. 31(3):530-536. PMCID: PMC4176919.
  • Hansell P, Welch WJ, Blantz RC, Palm F. (2013) Determinants of kidney oxygen consumption and their relationship to tissue oxygen tension in diabetes and hypertension. Clin Exp Pharmacol Physiol. 40(2):123-137. PMCID: PMC3951849.
  • Han SM, El Oussini H, Scekic-Zahirovic J, Vibbert J, Cottee P, Prasain JK, Bellen HJ, Dupuis L, Miller MA. (2013) VAPB/AL S8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis. PLoS Genet. 9(9):e1003738. PMCID: PMC3764199.
  • Hoang HD, Prasain JK, Dorand D, Miller MA. (2013) A heterogenous mixture of F-series prostaglandins promotes sperm guidance in the Caenorhabditis elegans reproductive tract. PLoS Genet. 9(1):e1003271. PMCID: PMC3561059.
  • Hull TD, Bolisetty S, Dealmeida AC, Litovsky SH, Prabhu SD, Agarwal A, George JF. (2013) Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase. Lab Invest. 93(8):868-879. PMCID: PMC3729748.
  • Kanbay M, Bayram Y, Solak Y, Sanders PW. (2013) Dietary potassium: a key mediator of the cardiovascular response to dietary sodium chloride. J Am Soc Hypertens. 7(5):395-400. PMCID: PMC4083820.
  • Lewington AJ, Cerda J, Mehta RL. (2013) Raising awareness of acute kidney injury: a global perspective of a silent killer. Kidney Int. 84(3):457-467. PMCID: PMC3758780.
  • Merscher-Gomez S, Guzman J, Pedigo CE, Lehto M, Aguillon-Prada R, Mendez A, Lassenius MI, Forsblom C, Yoo T, Villarreal R, Maiguel D, Johnson K, Goldberg R, Nair V, Randolph A, Kretzler M, Nelson RG, Burke GW 3rd, Groop PH, Fornoni A, the FinnDiane Study Group. (2013) Cyclodextrin protects podocytes in diabetic kidney disease. Diabetes. 62(11):3817-3827. PMCID: PMC3806621.
  • Mitchell T, Johnson MS, Ouyang X, Chacko BK, Mitra K, Lei X, Gai Y, Moore DR, Barnes S, Zhang J, Koizumi A, Ramanadham S, Darley-Usmar VM. (2013) Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita(+/Ins2)-derived β-cells. Am J Physiol Endocrinol Metab. 305(5):E585-E599. PMCID: PMC3761167.
  • Mrug M, Sanders PW. (2013) Beware the low HDAC11:males at risk for ischemic kidney injury. Am J Physiol Renal Physiol. 305(7):F973-F974. PMCID: PMC3798743.
  • Pacurari M, Xing D, Hilgers RH, Guo YY, Yang Z, Hage F. (2013) Endothelial cell transfusion ameloiorates endothelial dysfunction in 5/6 nephrectomized rats.Am J Physiol Heart Circ Physiol. 305(8):H1256-H1264. PMCID: PMC3798787.
  • Pasha DN, Davis JT, Rao F, Chen Y, Wen G, Fung MM, Mahata M, Zhang K, Trzebinska D, Mutapic M, Hightower CM, Lipokowitz MS, Ji M, Ziegler MG, Nievergelt CM, O’Connor DT. (2013) Heritable influence of DBH on adrenergic and renal function: twin and disease studies. PLoS One. 8(12):e82956. PMCID: PMC3876991.
  • Pegues MA, McCrory MA, Zarjou A, Szalai AJ. (2013) C-reactive protein exacerbates renal ischemia-reperfusion injury. Am J Physiol Renal Physiol. 304(11): F1358-F1365. PMCID: PMC3680688.
  • Prasain JK, Arbshahi A, Taub PR, Sweeney S, Moore R, Sharer JD, Barnes S. (2013) Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 913-914:161-168. PMCID: PMC3779072.
  • Prasain JK, Hoang HD, Edmonds JW, Miller MA. (2013) Prostaglandin extraction and analysis in Caenorhabditis elegans. J Vis Exp. (76). PMCID: PMC3728984
  • Reily C, Mitchell T, Chacko BK, Benavides G, Murphy MP, Darley-Usmar V. (2013) Mitochondrially targeted compounds and their impact on cellular bioenergetics. Redox Biol. 1(1):86-93. PMCID: PMC3647698.
  • Rieg T. (2013) A high-throughput method for measurement of glomerular filtration rate in conscious mice. J Vis Exp. 75:e50330. PMCID: PMC3679673.
  • Rieg T, Dominguez Rieg J. (2013) Connecting type A intercalated cell metabolic state to V-ATPase function: phosphorylation does matter! Am J Physiol Renal Physiol. 305(8):F1105-F1106. PMCID: PMC3798730.
  • Rieg T, Tang T, Uchida S, Hammond HK, Fenton RA, Vallon V. (2013) Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCC. Am J Pathol. 182(1):96-106. PMCID: PMC3532715.
  • Santriano J, Sharma K. (2013) Autophagy and metabolic changes in obesity-related chronic kidney disease. Nephrol Dial Transplant. 28 Suppl4:iv29-iv36. PMCID: PMC3854493.
  • Santriano J, Sharma K, Blantz RC, Deng A. (2013) Induction of AMPK activity corrects early pathophysiological alterations in the subtotal nephrectomy model of chronic kidney disease. Am J Physiol Renal Physiol. 305(5):F727-F733. PMCID: PMC3761200.
  • Sawant A, Schafer CC, Jin TH, Zmijewski J, Tse HM, Roth J, Sun Z, Siegal GP, Thannickal VJ, Ponnazhagan S, Deshane J. (2013) Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways. Cancer Res. 72(22):6609-6620. PMCID: PMC3854493.
  • Sharma N, Malarkey EB, Berbari NF, O’Connor AK, Vanden Heuvel GB, Mrug M, Yoder BK. (2013) Proximal tubule proliferation is insufficient to induce rapid cyst formation after cilia disruption. J Am Soc Nephrol. 24(3):456-464. PMCID: PMC3582198.
  • Shimamura M, Seleme MC, Guo L, Saunders U, Schoeb TR, George JF, Britt WJ. (2013) Ganciclovir prophylaxis improves late murine cytomegalovirus induced renal allograft damage. Transplantation. 95(1):48-53. PMCID: PMC3700407.
  • Singh P, Ricksten SE, Bragadottir G, Redfors B, Nordquist L. (2013) Renal Oxygenation and haemodynamics in acute kidney injury and chronic kidney disease. Clin Exp Pharmacol Physiol. 40(2):138-147. PMCID: PMC3710120.
  • Taler SJ, Agarwal R, Bakris GL, Flynn JT, Nilsson PM, Rahman M, Sanders PW, Textor SC, Weir MR, Townsend RR. (2013) KDOQI US Commentary on the 2012 KDIGO Clinical practice guideline for management of blood pressure in CKD. Am J Kidney Dis. 62(2):201-213. PMCID: PMC3929429.
  • Tolwani A. (2013) Continuous Renal Replacement Therapy for Acute Kidney Injury. N Engl J Med. 368(12):1160-1161. Commentary
  • Vallon V, Rose M, Gerasimova M, Satriano J, Platt KA, Koepsell H, Cunard R, Sharma K, Thomson SC, Rieg T. (2013) Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus. Am J Physiol Renal Physiol. 304(2):F156-F167. PMCID: PMC3543626.
  • Wang HE, Gaurav J, Glassock RJ, Warnock DG. (2013) Comparison of Absolute Serum Creatinine Changes versus KDIGO Consensus Definitions for Characterizing Stages of Acute Kidney Injury. Nephrol Dialy Transplant. 28(6):1447-1454. PMCID: PMC3685303.
  • Ying WZ, Aaron KJ, Sanders PW. (2013) Transforming growth factor-β regulates endothelial function during high salt intake in rats. Hypertension. 62(5):951-956. PMCID: PMC3972137.
  • Zarjou A, Bolisetty S, Joseph R, Traylor A, Apostolov EO, Arosio P, Balla J, Verlander J, Darshan D, Kuhn LC, Agarwal A. (2013) Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury. J Clin Invest. 123(10):4423-4434. PMCID: PMC3784534.
2012

  • Ahmed A, Fonarow GC, Zhang Y, Sanders PW, Allman RM, Arnett DK, Feller MA, Love TE, Aban IB, Levesque R, Ekundayo OJ, Dell'Italia LJ, Bakris GL, Rich MW. (2012) Renin-angiotensin inhibition in systolic heart failure and chronic kidney disease. Am J Med. 125(4):399-410. PMCID: PMC3324926
  • Askenazi DJ, Selewski DT, Paden ML, Cooper DS, Bridges BC, Zappitelli M, Fleming GM. (2012) Renal Replacement Therapy in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation. Clin J Am Soc Nephrol. 7(8):1328-1326. Review.
  • Askenazi DJ, Koralkar R, Hundley HE, Montesanti A, Parwar P, Sonjara S, Ambalavanan N. (2012) Urine Biomarkers Predict Acute Kidney Injury in Newborns. J Pediatr. 161(2):270-275. PMCID: PMC3598122.
  • Askenazi DJ. (2012) Do children with acute kidney injury require long-term evaluation for CKD? Am J Kidney Dis. 59(4):478-480. Review.
  • Blantz RC, Singh P, Deng A, Thomson SC, Vallon V. (2012) Acute Saline Expansion Increases Nephron Filtration and Distal Flow Rate but Maintains Tubuloglomerular Feedback Responsiveness: Role of Adenosine A1 Receptors. Am J Physiol Renal Physiol. 303(3):F405-F411. PMCID: PMC3433865
  • Borsting E, Cheng VP, Glass CK, Vallon V, Cunard R. (2012) Peroxisome proliferator-activated receptor-γ agonists repress epithelial sodium channel expression in the kidney. Am J Physiol Renal Physiol. 302(5):F540-F551. PMCID: PMC3353644
  • Buckoreelall K, Sun Y, Hobrath JV, Wilson L, Parker WB. (2012) Identification of Rv0535 as methylthioadenosine phosphorylase from Mycobacterium tuberculosis. Tuberculosis (Edinb). 92(2):139-147. PMCID: PMC3288397.
  • Claure-Del Granado R, Macedo E, Chertow GM, Soroko S, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. (2012) Toward the optimal dose metric in continuous renal replacement therapy. Int J Artif Organs. 35(6):413-424. PMCID: PMC4108204.
  • Cutter GR. (2012) Statistical cures and other fallacies. Mult Scler. 18(4):387-390. Review.
  • Dawoud D, Lyndon W, Mrug S, Bissler JJ, Mrug M. (2012) Impact of ultrasound-guided kidney biopsy simulation on trainee confidence and biopsy outcomes. Am J Nephrol, 36(6):570-574. PMCID: PMC3918883.
  • Feng W, Chumley P, Hua P, Rezonzew G, HAimes D, Duckworth MW, Xing D, Jaimes EA. (2012) Role of the transcription factor erythroblastosis virus E26 oncogen homolog-1 (ETS-1) as mediator of the renal proinflammatory and profibrotic effects of angiotensis II. Hypertension. 60(5):1226-1233. PMCID: PMC4309546.
  • Fleming GM, Askenazi DJ, Bridges BC, Cooper DS, Paden ML, Selewski DT, Zappitelli M. (2012) A Multicenter International Survey of Renal Supportive Therapy During ECMO: The Kidney Intervention During Extracorporeal Membrane Oxygenation (KIDMO) Group. ASAIO J. 58(4):407-414.
  • Giordano S, Lee J, Darley-Usmar VM, Zhang J. (2012) Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death. PLoS One. 7(9):e44610. PMCID: PMC3435291.
  • Gorboulev V, Schürmann A, Vallon V, Kipp H, Jaschke A, Klessen D, Friedrich A, Scherneck S, Rieg T, Cunard R, Veyhl-Wichmann M, Srinivasan A, Balen D, Breljak D, Rexhepaj R, Parker HE, Gribble FM, Reimann F, Lang F, Wiese S, Sabolic I, Sendtner M, Koepsell H. (2012) Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes. 61(1):187-196. PMCID: PMC3237647.
  • Greaney JL, DuPont JJ, Lennon-Edwards SL, Sanders PW, Edwards DG, Farquhar WB. (2012) Dietary sodium loading impairs microvascular function independent of blood pressure in humans: role of oxidative stress. J Physiol. 590(21):5519-5528. PMCID: PMC3515835.
  • Guo L, Agarwal A, George JF. (2012) Orthotopic Aortic Transplantation in Mice for the Study of Vascular Disease. J Vis Exp. 28(69):e4338. PMCID: PMC3565855.
  • Hardison MT, Brown MD, Snelgrove RJ, Blalock JE, Jackson P. (2012) Cigarette smoke enhances chemotaxis via acetylation or proline-glycine-proline. Front Biosci (Elite Ed). 4:2402-2409.
  • He L, Kim T, Long Q, Liu J, Wang P, Zhou Y, Ding Y, Prasain J, Wood PA, Yang Q. (2012) Carnitine palmitoyltransferase-1b deficiency aggravates pressure overload-induced cardiac hypertrophy caused by lipotoxicity. Circulation. 126(14):1705-1716. PMCID: PMC3484985.
  • Higdon AN, Benavides GA, Chacko BK, Ouyang X, Johnson MS, Landar A, Zhang J, Darley-Usmar VM. (2012) Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy. Am J Physiol Heart Circ Physiol. 302(7):H1394-H1409. PMCID: PMC3330785.
  • Hovater MB, Sanders PW. (2012) Effect of dietary salt on regulation of TGF-β in the kidney. Semin Nephrol. 32(3):269-276. PMCID: PMC3407676.
  • Hua P, Feng W, Rezonzew G, Chumley P, Jaimes EA. (2012) The transcription factor ETS-1 regulates angiotensin II-stimuated fibronectin production in mesangial cells. Am J Physiol Renal Physiol. 302(11) F1418-F1429.
  • James DB, Yother J. (2012) Genetic and biochemical characterizations of enzymes involved in Streptococcus pneumonia serotype 2 capsule synthesis demonstrate that Cps2T (WchF) catalyzes the committed step by addition of β1-4 rhamnose, the second sugar residue in the repeat unit. J Bacteriol. 194(23):6479-6489. PMCID: PMC3497468.
  • Jetton JG, Askenazi DJ. (2012) Update on acute kidney injury in the neonate. Curr Opin Peditar. 24(2):191-196. Review.
  • Kelpke SS, Chen B, Bradley K, Teng X, Chumley P, Moore B, Head H, Viera L, Thompson JA, Crossman DK, Bray MS, Eckhoff DE, Agarwal A, Patel RP. (2012) Sodium nitrite therapy protects against brain death induced kidney injury and improves post-transplantation outcomes. Kidney Int. 82(3):304-313. PMCID: PMC3412933.
  • Kennedy RE, Schneider LS, Cutter GR. (2012) Biomarker Positive and Negative Subjects in the ADNI Cohort: Clinical Characterization. Curr Alzheimer Res. 9(10):1135-1141. PMC Journal - In Process.
  • Kim J, Zarjou A, Traylor AM, Hull TD, Jaimes EA, George JF, Mikhail FM, Agarwal A. (2012) In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice. Kidney Int. 82(3):278-291. PMCID: PMC3396739.
  • Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F. (2012) G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci USA. 109(52):21462-21467. PMCID: PMC3535663.
  • Lang F, Vallon V. (2012) Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport. Clin Exp Nephrol. 16(1):73-80. Review
  • McClure M, DeLucas LJ, Wilson L, Ray M, Rowe SM, Wu X, Dai Q, Hong JS, Sorscher EJ, Kappes JC, Barnes S. (2012) Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications. Protein Eng Des Sel. 25(1):7-14. PMCID: PMC3276306.
  • Mehta, RL: (2012) Acute kidney injury: AKI in acute myocardial infarction-are we making progress? Nat Rev Nephrol. 8(6):322-323. Review.
  • Mitchell T, Darley-Usmar V. (2012) Metabolic syndrome and mitochondrial dysfunction: insights from preclinical studies with a mitochondrially targeted antioxidant. Free Radic Biol Med. 52(5):838-840. PMCID: PMC3992111.
  • Moskowitz-Kassai E, Mackelaite L, Chen J, Patel K, Dadhania DM, Gross SS, Chander P, Delaney V, Deng L, Chen L, Cui X, Suthanthiran M, Goligorsky MS. (2012) Excretion of anti-angiogenic proteins in patients with chronic allograft dysfunction. Nephrol Dial Transplant. 27(2):494-497. PMCID: PMC3275786.
  • Pan F, Goh JW, Cutter G, Su W, Pleimes D, Wang C. (2012) Long-Term Cost-Effectiveness Model of Interferon Beta-1b in the Early Treatment of Multiple Sclerosis in the United States. Clin Ther. 34(9):1966–1976. PMC Journal - In Process.
  • Perianayagam MC, Tighiouart H, Liangos O, Kuznetsov D, Wald R, Rao F, O’Connor DT, Jaber B. (2012) Polymorphisms in the Myeloperoxidase Gene Locus and Acute Kidney Injury: A Two-Step Genetic Association Study. Kidney Int. 82(8):909-919. PMCID: PMC3461107.
  • Regev D, Surolia R, Karki S, Zolak J, Montes-Worboys A, Oliva O, Guroji P, Saini V, Steyn AJ, Agarwal A, Antony VB. (2012) Heme oxygenase-1 promotes granuloma development and protects agains dissemination of mycobacteria. Lab Invest. 92(11):1541-1552. PMCID: PMC4017357.
  • Rieg T, Gerasimova M, Murray F, Masuda T, Tang T, Rose M, Drucker DJ, Vallon V. (2012) Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice. Am J Physiol Renal Physiol. 303(7):F963-F971. PMCID: PMC3469689.
  • Rezonzew G, Chumley P, Feng W, Hua P, Siegal G, Jaimes EA. (2012) Nicotine exposure and the progression of chronic kidney disease: role of the 7-nicotine acetylcholine receptor. Am J Physiol Renal Physiol. 303(2):F304–F312. PMCID: PMC3404588.
  • Saag KG, Mohr PE, Esmail L, Mudano AS, Wright N, Beukelman T, Curtis JR, Cutter G, Delzell E, Gary LC, Harrington TM, Karkare S, Kilgore ML, Lewis CE, Moloney R, Oliveira A, Singh JA, Warriner A, Zhang J, Berger M, Cummings SR, Pace W, Solomon DH, Wallace R, Tunis SR. (2012) Improving the efficiency and effectiveness of pragmatic clinical trials in older adults in the United States. Contemp Clin Trials. 33(6):1211-1216. PMCID: PMC3675785.
  • Sabolic I, Vrhovac I, Eror DB, Gerasimova M, Rose M, Breljak D, Ljubojevic M, Brzica H, Sebastiani A, Thal SC, Sauvant C, Kipp H, Vallon V, Koepsell H. (2012) Expression of NA+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences. Am J Physiol Cell Physiol. 302(8):C1174-C1188. PMCID: PMC3774553.
  • Sanders PW. (2012) Mechanisms of light chain injury along the tubular nephron. J Am Soc Nephrol. 23(11):1777-1781. Review
  • Schoeb TR, Jarmi T, Hicks JM, Henke S, Zarjou A, Hitoshi S, Kramer P, Novak J, Agarwal A, Bullard DC. (2012) eNOS inhibits the development of autoimmune-mediated vasculitis. Arthritis Rheum. 64(12):4114-4124. PMCID: PMC3510336.
  • Singh P, Blantz RC, Rosenberger C, Gabbai FB, Schoeb TR, Thomson SC. (2012) Aberrant tubuloglomerular feedback and HIF-1α confer resistance to ischemia after subtotal nephrectomy. J Am Soc Nephrol. 23(3):483-493. PMCID: PMC3294306.
  • Susantitaphong P, Perianayagam MC, Kang SW, Zhang W, Rao F, O’Connor DT, Jaber BL. (2012) Association of functional kallikrein-1 promoter polymorphisms and acute kidney injury: a case-control and longitudinal cohort study. Nephron Clin Pract. 122(3-4):107-113. PMCID: PMC3700581.
  • Tan CK, Carey AJ, Cui X, Webb RI, Ipe D, Crowley M, Cripps AW, Benjamin WH Jr, Ulett KB, Schembri MA, Ulett GC. (2012) Genome-wide mapping of cystitis due to Streptococcus agalactiae and Escherichia coli in mice identifies a unique bladder transcriptome that signifies pathogen-specific antimicrobial defense against urinary tract infection. Infect Immun. 80(9):3145-3160. PMCID: PMC3418756.
  • Taub PR, Borden KC, Fard A, Maisel A. (2012) Role of biomarkers in the diagnosis and prognosis of acute kidney injury in patients with cardiorenal syndrome. Expert Rev Cardiovasc Ther. 10(5):657-667. PMCID: PMC4060800.
  • Teerlink JR, Iragui VJ, Mohr JP, Carson PE, Hauptman PJ, Lovett DH, Miller AB, Piña IL, Thomson S, Varosy PD, Zile MR, Cleland JG, Givertz MM, Metra M, Ponikowski P, Voors AA, Davison BA, Cotter G, Wolko D, Delucca P, Salerno CM, Mansoor GA, Dittrich H, O'Connor D, Massie BM. (2012) The safety of an adenosine A(1)-receptor antagonist, rolofylline, in patients with acute heart failure and renal impairment: findings from PROTECT. Drug Saf. 35(3):233-244.
  • Thomson SC, Rieg T, Miracle C, Mansoury H, Whaley J, Vallon V, Singh P. (2012) Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat. Am J Physiol Regul Integr Comp Physiol. 302(1):R75-R83. PMCID: PMC3349378.
  • Toney GM, Vallon V, Stockand JD. (2012) Intrinsic control of sodium excretion in the distal nephron by inhibitory purinergic regulation of the epithelial Na(+) channel. Curr Opin Nephrol Hypertens. 21(1):52-60. PMCID: PMC3689579.
  • Vallon V, Eraly SA, Ramachandra Rao S, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T. (2012) A role for the organic anion transporter OAT3 in renal creatinine secretion in mice. Am J Physiol Renal Physiol. 302(10):F1293-F1299. PMCID: PMC3362066.
  • Vallon V, Stockand J, Rieg T. (2012) P2Y receptors and kidney function. Wiley Interdiscip Rev Membr Transp Signal. 1(6):731-742. PMCID: PMC3490424.
  • Vallon V, Thomson SC. (2012) Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney. Annu Rev Physiol. 74:351-375. PMCID: PMC3807782.
  • Wall SB, Oh JY, Diers AR, Landar A. (2012) Oxidative modification of proteins: an emerging mechanism of cell signaling. Front Physiol.3:369. PMCID: PMC3442266.
  • Wang HE, Muntner P, Chertow GM, Warnock DG. (2012) Acute kidney injury and mortality in hospitalized patients. Am J Nephrol. 35(4):349-355. PMCID: PMC3362180.
  • Ying WZ, Aaron KJ, Sanders PW. (2012) Effect of aging and dietary salt and potassium intake on endothelial PTEN (Phosphatase and tensin homolog on chromosome 10) function. PLoS ONE. 7(11):e41785. PMCID: PMC3492426.
  • Ying WZ, Allen CE, Curtis LM, Aaron KJ, Sanders PW. (2012) Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model. J Clin Invest. 122(5):1777-1785. PMCID: PMC3336971.
  • Ying WZ, Wang PX, Sanders PW. (2012) Pivotal role of apoptosis signal-regulating kinase 1 in monoclonal free light chain-mediated apoptosis. Am J Pathol. 180(1):41-47. PMCID: PMC3338338.
  • Zarjou A, Sanders PW, Mehta RL, Agarwal A. (2012) Enabling innovative translational research in acute kidney injury. Clin Transl Sci. 5(1):93-101. PMCID: PMC3292183.
  • Zarjou A, Agarwal A. (2012) Superoxide in AVF Dysfunction: a new target for intervention. Am J Physiol Renal Physiol 303(12):F1599-F1600. PMCID: PMC3532471.
  • Zarjou A, Agarwal A. (2012) Heme oxygenase-1 as a target for TGF-β in kidney disease. Semin Nephrol. 32(3):277-286. PMCID: PMC3407376
  • Zarjou A, Guo L, Sanders PW, Mannon RB, Agarwal A, George JF. (2012) A reproducible mouse model of chronic allograft nephropathy with vasculopathy. Kidney Int. 82(11):1231-1235. PMCID: PMC3495090.
  • Zhou J, Ouyang X, Schoeb TR, Bolisetty S, Cui X, Mrug S, Yoder BK, Johnson MR, Szalai AJ, Mrug M. (2012) Kidney Injury Accelerates Cystogenesis via Pathways Modulated by Heme Oxygenase and Complement. J Am Soc Nephrol. 23(7):1161-1171. PMCID: PMC3380643.
2011

  • Aaron KJ, Campbell RC, Judd SE, Sanders PW, Muntner P. (2011) Association of dietary sodium and potassium intakes with albuminuria in normal-weight, overweight, and obese participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Clin Nutr. 94(4):1071-1078. PMCID: PMC3173025.
  • Anderson JT, Zeng M, Li Q, Stapley R, Moore DR 2nd, Chenna B, Fineberg N, Zmijewski J, Eltoum IE, Siegal GP, Gaggar A, Barnes S, Velu SE, Thannickal VJ, Abraham E, Patel RP, Lancaster JR Jr, Chaplin DD, Dransfield MT, Deshane JS. (2011) Elevated levels of NO are localized to distal airways in asthma. Free Radic Biol Med. 50(11):1679-1688. PMCID: PMC3124865.
  • Askenazi D. (2011) Evaluation and management of critically ill children with acute kidney injury. Curr Opin Pediar. 23(2):201-207. PMCID: PMC3289546.
  • Askenazi DJ, Koralkar R, Levitan EB, Goldstein SL, Devarajan P, Khandrika S, Mehta RL, Ambalavanan N. (2011) Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants. Pediatr Res. 70(3):302-306. PMCID: PMC3152663.
  • Askenazi DJ, Montesanti A, Hunley H, Koralkar R, Pawar P, Shuaib F, Liwo A, Devarajan P, Ambalavanan N. (2011) Urine biomarkers predict acute kidney injury and mortality in very low birth weight infants. J Pediatr. 159(6):907-912. PMCID: PMC5065006.
  • Bell PD, Fitzgibbon W, Sas K, Stenbit AE, Amria M, Houston A, Reichert R, Gilley S, Siegal GP, Bissler J, Bilgen M, Chou PC, Guay-Woodford L, Yoder B, Haycraft CJ, Siroky B. (2011) Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis. J Am Soc Nephrol. 22(5):839-848. PMCID: PMC3083306.
  • Blantz RC, Singh P. (2011) Analysis of the Prerenal Contributions to Acute Kidney Injury. Contrib Nephrol. 174:4-11. Review.
  • Bolisetty S, Agarwal A. (2011) Urine albumin as a biomarker in acute kidney injury. Am J Physiol Renal Physiol. 300(3):F626-F627. PMCID: PMC3064133.
  • Bowling CB, Feller MA, Mujib M, Pawar PP, Zhang Y, Ekundayo OJ, Aban IB, Love TE, Sanders PW, Anker SD, Fonarow GC, Ahmed A. (2011) Relationship between stage of kidney disease and incident heart failure in older adults. Am J Nephrol. 34(2):135-141. PMCID: PMC3136373.
  • Buckoreelall K, Wilson L, Parker WB. (2011) Identification and characterization of two adenosine phosphorylase activities in Mycobacterium smegmatis. J Bacteriol. 193(20):5668-5674. PMCID: PMC3187226.
  • Buckingham SC, Campbell SL, Haas BR, Montana V, Robel S, Ogunrinu T, Sontheimer H. (2011) Glutamate release by primary brain tumors induces epileptic activity. Nat Med. 17(10:1269-1274. PMCID: PMC3192231.
  • Claure-Del Granado R, Macedo E, Chertow GM, Soroko S, Himmelfarb J, Ikizler AT, Paganini EP, Mehta RL. (2011) Effluent volume in continuous renal replacement therapy overestimates the delivered dose of dialysis. Clin J Am Soc Nephrol. 6(3):467-475. PMCID: PMC3082402.
  • Claure-Del Granado R, Mehta RL. (2011) Withholding and withdrawing renal replacement support in AKI. Semin Dial. 24(2):208-214. Review.
  • Claure-Del Granado, R, Mehta RL. (2011) Assessing and delivering dialysis dose in AKI. Semin Dial. 24(2):157-163. Review.
  • Clement LC, Avila-Casado C, Macé C, Soria E, Bakker WW, Kersten S, Chugh SS. (2011) Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med. 17(1):117-122. PMCID: PMC3021185.
  • Dranka BP, Benavides GA, Diers AR, Giordano S, Zelickson BR, Reily C, Zou L, Chatham JC, Hill BG, Zhang J, Landar A, Darley-Usmar VM. (2011) Assessing bioenergetic function in response to oxidative stress by metabolic profiling. Free Radic Biol Med. 51(9):1621-1635. PMCID: PMC3548422.
  • Du Y, Zappitelli M, Mian A, Bennett M, Ma Q, Devarajan P, Mehta R, Goldstein SL. (2011) Urinary biomarkers to detect acute kidney injury in the pediatric emergency center. Pediatr Nephrol. 26(2):267-274.
  • Filippatos GS, Ahmed MI, Gladden JD, Mujib M, Aban IB, Love TE, Sanders PW, Pitt B, Ankar SD, Ahmed A. (2011) Hyperuricaemia, chronic kidney disease, and outcomes in heart failure: potential mechanistic insights from epidemiological data. Eur Heart J. 32(6):712-720. PMCID: PMC3056205.
  • Floyd KA, Stella DR, Wang CC, Laurentz S, McCabe GP, Srivastava OP, Barnes S. (2011) Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat. Exp Eye Res. 92(2):120-127. PMCID: PMC3034771.
  • Horikawa YT, Panneerselvam M, Kawaraguchi Y, Tsutsumi YM, Ali SS, Balijepalli RC, Murray F, Head BP, Niesman IR, Rieg T, Vallon V, Insel PA, Patel HH, Roth DM. (2011) Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling. J Am Coll Cardiol. 57(22):2273-2283. PMCID: PMC3236642.
  • Hutchison CA, Batuman V, Behrens J, Bridoux F, Sirac C, Dispenzieri A, Herrera GA, Lachmann H, Sanders PW. (2011) International Kidney and Monoclonal Gammopathy Research Group. The pathogenesis and diagnosis of acute kidney injury in multiple myeloma. Nat Rev Nephrol. 8(1):43-51. PMCID: PMC3375610.
  • Kanbay M, Chen Y, Solak Y, Sanders PW. (2011) Mechanisms and consequences of salt sensitivity and dietary salt intake. Curr Opin Nephrol Hypertens. 20(1):37-43. PMCID: PMC3089903.
  • Kang SW, Shih PA, Mathew RO, Mahata M, Biswas N, Rao F, Yan L, Bouchard J, Malhotra R, Tolwani A, Khandrika S, Mehta RL, O'Connor DT. (2011) Renal kallikrein excretion and epigenetics in human acute kidney injury: Expression, mechanisms and consequences. BMC Nephrol. 12:27. PMCID: PMC3154145.
  • Kister I, Chamot E, Bacon JH, Cutter G, Herbert J; New York State Multiple Sclerosis Consortium. (2011) Trend for decreasing Multiple Sclerosis Severity Scores (MSSS) with increasing calendar year of enrollment into the New York State Multiple Sclerosis Consortium. Mult Scler. 17(6):725-733
  • Lee SA, Belyaeva OV, Wu L, Kedishvili NY. (2011) Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture. J Biol Chem. 286(15):13550-13560. PMCID: PMC3075701.
  • Li FJ, Kubagawa Y, McCollum MK, Wilson L, Motohashi T, Bertoli LF, Barton JC, Barnes S, Davis RS, Kubagawa H. (2011) Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (FcμR) in patients with chronic lymphocytic leukemia. Blood. 118(18):4902-4909. PMCID: PMC3208298.
  • Li F, Glinskii OV, Zhou J, Wilson LS, Barnes S, Anthony DC, Glinsky VV. (2011) Identification and analysis of signaling networks potentially involved in breast carcinoma metastasis to the brain. PLoS One. 6(7) e21977. PMCID: PMC3136937.
  • Lu A, Miao M, Schoeb, TR, Agarwal A, Murphy-Ullrich JE. (2011) Blockade of TSP1-dependent TGF-β activity reduces renal injury and proteinuria in a murine model of diabetic nephropathy. Am J Pathol. 178(6):2573-2586. PMCID: PMC3124297.
  • Macedo E, Malhotra R, Claure-Del Granado R, Fedullo P, Mehta RL. (2011) Defining urine output criterion for acute kidney injury in critically ill patients. Nephrol Dial Transplant. 26(2):509-515. PMCID: PMC3108356.
  • Marrie RA, Cutter G, Tyry T. (2011) Substantial adverse association of visual and vascular comorbidities on visual disability in multiple sclerosis. Mult Scler. 17(12):1464-1471.
  • Mehta RL. (2011) Management of acute kidney injury: it's the squeaky wheel that gets the oil! Clin J Am Soc Nephrol. 6(9):2102-2104. Review.
  • Mehta RL, Bouchard J, Soroko S, Ikizler TA, Paganini EP, Chertow GM, Himmelfarb J. (2011) Sepsis as a Cause and Consequence of Acute Kidney Injury: Program to Improve Care in Acute Renal Disease (PICARD). Intensive Care Med. 37(2):241-248. PMCID: PMC3028102.
  • Mehta RL. (2011) Biomarker explorations in acute kidney injury: the journey continues. Kidney Int. 80(4):332-334. Review.
  • Perianayagam MC, Tighiouart H, Nievergelt CM, O'Connor DT, Liangos O, Jaber BL. (2011) CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study. Nephron Extra. 1(1):112-123. PMCID: PMC3290849.
  • Rajbhandari R, Peng N, Moore R, Arabshahi A, Wyss JM, Barnes S, Prasain JK. (2011) Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry. J Agric Food Chem. 59(12):6682-6688. PMCID: PMC3165050.
  • Rieg T, Gerasimova M, Boyer JL, Insel PA, Vallon V. (2011) P2Y2‚ receptor activation decreases blood pressure and increases renal Na+ excretion. Am J Physiol Regul Integr Comp Physiol. 301(2):R510-R518. PMCID: PMC3154711
  • Roy B, Pawar PP, Desai RV, Fonarow GC, Mujib M, Zhang Y, Feller MA, Ovalle F, Aban IB, Love TE, Iskandrian AE, Deedwania P, Ahmed A. (2011) A propensity-matched study of the comparative effectiveness of angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors in heart failure patients age ≥ 65 years. Am J Cardiol. 108(10):1443-1448. PMCID: PMC3324944.
  • Sanders PW. (2011) Light chain-mediated tubulopathies. Contrib Nephrol. 169:262-269. Review.
  • Shimamura M, Saunders U, Rha B, Guo L, Cassady KA, George JF, Britt WJ. (2011) Ganciclovir transiently attenuates murine cytomegalovirus-associated renal allograft inflammation. Transplantation. 92(7):759-766. PMC Journal – In Process.
  • Singh P, Okusa MD. (2011) Role of Tubuloglomerular Feedback in the Pathogenesis of AKI. Controversies in Acute Kidney Injury. Contrib Nephrol. 174:12-21. Invited review.
  • Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. (2011) Functional Maturation of Drug Transporters in the developing, neonatal and postnatal Kidney. Mol Pharmacol. 80(1):147-154. PMCID: PMC3127534.
  • Thomson SC, Blantz RC. (2011) Biophysical basis of glomerular filtration. In Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology, Fifth Edition, Alpern RJ, Caplan M, and Moe OW (Eds) In Press 2011. Book Chapter.
  • Thomson SC, Blantz RC. (2011) Glomerular filtration rate. In Comprehensive Physiology. Pollack DM, Garvin J (eds), In Press, 2011. Book Chapter.
  • Vallon V, Komers R. (2011) Pathophysiology of the diabetic kidney. Comp Physiol. 1(3):1175-1232. Review.
  • Vallon V, Platt KA, Cunard R, Schroth J, Whaley J, Thomson SC, Koepsell H, Rieg T. (2011) SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol. 22(1):104-112. PMCID: PMC3014039
  • Vallon V, Rieg T. (2011) Regulation of renal NaCl and water transport by the ATP/UTP/P2Y2 receptor system. Am J Physiol Renal Physiol. 301(3):F463-F475. PMCID: PMC3174559.
  • Vallon V, Thomson S. (2011) Anomalous role for dietary salt in diabetes mellitus? Nat Rev Endocrinol.7(7):377-378. PMCID: PMC3335262.
  • Vallon V. (2011) The proximal tubule in the pathophysiology of the diabetic kidney. Am J Physiol Regul Integr Comp Physiol. 300(5):R1009-R1022. PMCID: PMC3094037
  • Vallon V. (2011) Molecular determinants of renal glucose reabsorption focus on “Glucose transport by human renal Na+-d-glucose co-transporters SGLT1 & SGLT2”. Am J Physiol Cell Physiol. 300(1):C6-C8. PMCID: PMC3023181.
  • Weigent DA. (2011) High molecular weight isoforms of growth hormone in cells of the immune system. Cell Immunol. 271(1):44-52. PMCID: PMC3751194.
  • Wu QQ, Wang Y. Senitko M, Meyer C, Wigley CW. Ferguson DA, Grossman E, Chen J, Zhou ZJ, Hartono J, Winterberg P. Chen B, Agarwal A, Lu CY. (2011) Bardoxolone Methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes - Nrf2, PPARγ, and HO-1. Am J Physiol Renal Physiol. 300(5):F1180-F1192. PMCID: PMC3094059.
  • Ying WZ, Wang PX, Aaron KJ, Basnayake K, Sanders PW. (2011) Immunoglobulin light chains activate nuclear factor-β in renal epithelial cells through a Src-dependent mechanism. Blood. 117(4):1301-1307. PMCID: PMC3056473.
  • Zarjou, A, Agarwal A. (2011) Sepsis and acute kidney injury. J Am Soc Nephrol. 22(6):999-1006. Review.
  • Zarjou A, Kim J, Traylor AM, Sanders PW, Balla J, Agarwal A, Curtis LM. (2011) Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1. Am J Physiol Renal Physiol. 300(1):F254-F262. PMCID: PMC3023217.
  • Zarjou A, Yang S, Abraham E, Agarwal A, Liu G. (2011) Identification of a microRNA signature in renal fibrosis: Role of miR21. Am J Physiol Renal Physiol. 301(4):F793-F801. PMCID: PMC3191802.
  • Zavaczki E, Jeney V, Agarwal A, Zarjou A, Oros M, Katko M, Varga Z, Balla G, Balla J. (2011) Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells. Kidney Int. 80(7):731-739. PMCID: PMC3257044.
  • Zhang Y, Fonarow GC, Sanders PW, Farahmand F, Allman RM, Aban IB, Love TE, Levesque R, Kilgore ML, Ahmed A. (2011) A propensity-matched study of the comparative effectiveness of angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors in heart failure patients age ≥ 65 years. Am J Cardiol. 108(10):1443-1448. PMCID: PMC3324349.
  • Zheng Y, Qin H, Frank SJ, Deng L, Litchfield DW, Tefferi A, Pardanani A, Lin FT, Li J, Sha B, Benveniste EN. (2011) A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway. Blood. 118(1):156-166. PMCID: PMC3139382.
2010

  • Alam A, O'Connor DT, Perianayagam MC, Kolyada AY, Chen Y, Rao F, Mahata M, Mahata S, Liangos O, Jaber BL. (2010) Phenylethanolamine N-Methyltransferase Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury. Nephron Clin Pract. 114(4):c253-c259. PMCID: PMC2865401.
  • Basnayake K, Ying WZ, Wang PX, and Sanders P. (2010) Immunoglobulin Light Chains Activate Tubular Epithelial Cells Through Redox Signaling. J Am Soc Nephrol. 21(7):1165-1173. PMCID: PMC3152234.
  • Bhatnagar V, Garcia EP, O’Connor DT, Brophy VH, Alcaraz J, Richard E, Bakris GL, Middleton JP, Norris KC, Wright J, Hiremath L, Contreras G, Appel LJ, Lipkowitz MS, AASK Study Investigators. (2010) CYP3A4 and CYP3A5 Polymorphisms and Blood Pressure Response to Amlodipine among African-American Men and Women with Early Hypertensive Renal Disease. Am J Nephrol. 31(2):95-103. PMCID: PMC2853591.
  • Bolisetty S, Traylor AM, Kim J, Joseph R, Ricart K, Landar A, Agarwal A. (2010) Heme oxygenase-1 inhibits renal tubular macroautophagy in acute kidney injury. J Am Soc Nephrol. 21(10):1702-1712. PMCID: PMC3013546.
  • Bouchard J, Macedo E, Mehta RL. (2010) Dosing of Renal Replacement Therapy in Acute Kidney Injury: Lessons Learned From Clinical Trials. Am J Kidney Dis. 55(3):570-579. Review.
  • Bouchard J, Macedo E, Soroko S, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. (2010) Comparison of methods for estimating glomerular filtration rate in critically ill patients with acute kidney injury. Nephrol Dial Transplant. 25(1):102-107. PMCID: PMC2910324.
  • Bouchard J, Mehta RL. (2010) Fluid Balance Issues in the Critically Ill Patient. Contrib Nephrol. 164:69. Review.
  • Bowling CB, Pitt B, Ahmed MI, Aban IB, Sanders PW, Mujib M, Campbell RC, Love TE, Aronow WS, Allman RM, Bakris GL, Ahmed A. (2010) Hypokalemia and outcomes in patients with chronic heart failure and chronic kidney disease: findings from propensity-matched studies. Circ Heart Fail. 3(2):253-260. PMCID: PMC2909749.
  • Chacko BK, Reily C, Srivastava A, Johnson MS, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V. (2010) Prevention of diabetic nephropathy in the Ins2+/-Akita J mice by the mitochondria-targeted therapy Mito-Q. Biochem J. 432(1):9-19. PMCID: PMC2973231.
  • Chen Y, Lipkowitz MS, Salem RM, Fung MM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Hicks PJ, Bowden DW, Freedman BI, O’Connor DT. (2010) Progression of chronic kidney disease (CKD): Adrenergic genetic influence on GFR decline in hypertensive nephrosclerosis. Am J Nephrol. 32(1):23-30. PMCID: PMC2914391.
  • Chen Y, Rao F, Wen G, Gayen JR, Zhang K, Vaingankar SM, Biswas N, Mahata M, Friese RS, Fung MM, Salem RM, Nievergelt C, Bhatnagar V, Hook VY, Ziegler MG, Mahata SK, Hamilton BA, O’Connor DT. (2010) Naturally occurring genetic variants in human chromogranin A (CHGA) associated with hypertension as well as hypertensive renal disease. Cell Mol Neurobiol. 30(8):1395-1400. PMCID: PMC3008929.
  • Chen Y, Salem RM, Rao F, Fung MM, Bhatnagar V, Pandey B, Mahata M, Waalen J, Nievergelt CM, Lipkowitz MS, Hamilton BA, Mahata SK, O'Connor DT. (2010) Common charge-shift mutation Glu65Lys in K+ channel β1‚ -Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease. Am J Nephrol. 32(5):414-424. PMCID: PMC2975731
  • Deng A, Arndt MA, Satriano J, Singh P, Rieg T. (2010) Renal Protection in Chronic Kidney Disease: Hypoxia Inducible Factor Activation Versus Angiotensin II Blockade. Am J Physiol Renal Physiol. 299:(6):F1365-F1373. PMCID: PMC3006314.
  • Deshane J, Kim J, Bolisetty S, Hock TD, Hill-Kapturczak N, Agarwal A. (2010) Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells. J Biol Chem. 285(22):16476-16486. PMCID: PMC2878004.
  • Diers AR, Higdon AN, Ricart KC, Johnson MS, Agarwal A, Kalyanaraman B, Landar A, Darley-Usmar VM. (2010) Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12, 14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. Biochem J. 426(1):31-41. PMCID: PMC3079364.
  • Edmonds JW, Prasain JK, Dorand D, Yang Y, Hoang HD, Vibbert J, Kubagawa HM, Miller MA. (2010) Insulin/FOXO signaling regulates ovarian prostaglandins critical for reproduction. Dev Cell. 19(6):858-871. PMCID: PMC3026445.
  • Fogo AB, Bostad L, Svarstad E, Molls S, Barbey F, Geldenhuys L, West M, Ferluga D, Vujkovac B, Howie AJ, Burns A, Waldek S, Noel LH, Grunfeld JP, Valbuena C, Oliveira JP, Muller J, Brunig F, Zhang X, Warnock WG. (2010) Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN). Nephrol Dial Transplant. 25(7):2168-2177. PMCID: PMC2902894.
  • George J, Agarwal A. (2010) Hydrogen: another gas with therapeutic potential. Kidney Int. 77(2):85-87. Review.
  • Hellman NE, Liu Y, Merkel E, Austin C, Le Corre S, Beier DR, Sun Z, Sharma N, Yoder BK, Drummond IA. (2010) The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proc Natl Acad Sci USA. 107(43):18499-18504. PMCID: PMC2972951.
  • Higdon AN, Dranka BP, Hill BG, Oh JY, Johnson MS, Landar A, Darley-Usmar VM. (2010) Methods for imaging and detecting modification of proteins by reactive lipid species. Free Radic Biol Med. 47(3):201-212. PMCID: PMC2727357.
  • Lang F, Huang DY, Vallon V. (2010) SGK, renal function and hypertension. J Nephrol. Suppl 16:S124-S129. PMCID: PMC4026186.
  • Macedo E, Bouchard J, Soroko SH, Chertow GM, Himmelfarb J, Ikizker TA, Paganini EP. Mehta RL. (2010) Fluid accumulation, recognition and staging of acute kidney injury in critically-ill patients. Crit Care. 14(3):R82. PMCID: PMC2911707.
  • Macedo E, Mehta RL. (2010) Early vs Late start of dialysis: it’s all about timing. Crit Care. 14(1):112. PMCID: PMC2875487.
  • Macedo E, Mehta RL. (2010) Prerenal Azotemia in Congestive Heart Failure. Contrib Nephrol. 164:79-87. Review.
  • Marrie RA, Rudick R, Horwitz R, Cutter G, Tyry T, Campagnolo D, Vollmer T. (2010) Vascular comorbidity is associated with more rapid disability progression in multiple sclerosis. Neurology. 74(13):1041-1047. PMCID: PMC2848107.
  • Mehta RL. (2010) Timed and targeted therapy for acute kidney injury: a glimpse of the future. Kidney Int. 77(11):947-949. Review.
  • Morse E, Schroth J, You YH, Pizzo DP, Okada S, Ramachandrrarao S, Vallon V, Sharma K, Cunard R. (2010) TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP-1. Am J Physiol Renal Physiol. 299(5):F965-F972. PMCID: PMC2980398.
  • Mrug M, Bissler J. (2010) Simulation of real-time ultrasound-guided renal biopsy. Kidney Int. 78(7):705-707. PMCID: PMC3420353.
  • Parks DJ, Agarwal A, George JF. (2010) Heme oxygenase-1 Expression in murine dendritic cell subpopulations: Effect on CD8+ dendritic cell differentiation in vivo. Am J Pathol. 176(6):2831-2839. PMCID: PMC2877844.
  • Pochynyuk O, Rieg T, Bugaj V, Schroth J, Fridman A, Boss GR, Insel PA, Stockand JD, Vallon V. (2010) Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2 receptor tone. FASEB J. 24(6):2056-2065. PMCID: PMC2874475.
  • Rieg T, Tang T, Murray F, Schroth J, Insel PA, Fenton RA, Hammond HK, Vallon V. (2010) Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in renal inner medulla. J Am Soc Nephrol. 21(12):2059-2068. PMCID: PMC3014019.
  • Rodriguez-Flores JL, Zhang K, Kang SW, Wen G, Ghosh S, Friese RS, Mahata SK, Subramaniam S, Hamilton BA, O’Connor DT. (2010) Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/ experimental approach. Mamm Genome. 21(3-4):195-204. PMCID: PMC2844968.
  • Salem RM, O’Connor DT, Schork NJ. (2010) Curve-Based Multivariate Distance Matrix Regression (CMDMR) Analysis: Application to Genetic Association Analyses Involving Repeated Measures. Physiol Genomics. 42(2):236-247. PMCID: PMC3032281.
  • Sanders PW, Agarwal A. (2010) Acute Kidney Injury. ACP Medicine, A textbook of Medicine published by the American College of Physicians. Editor-in-chief – Elizabeth G. Nabel, MD. Decker Intellectual Properties, Hamilton, ON L8N 3K7, Canada. Book Chapter
  • Satriano J, Mansoury H, Deng A, Sharma K, Vallon V, Blantz RC, Thomson SC. (2010) Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes. Am J Physiol Cell Physiol. 299(2):C374-C380. PMCID: PMC2928628.
  • Singh P, Rifkin DE, Blantz RC. (2010) Chronic kidney disease: an inherent risk factor for acute kidney injury? Clin J Am Soc Nephrol. 5(9):1690-1695. Review.
  • Singh P, Thomson SC. (2010) Renal homeostasis and tubuloglomerular feedback. Curr Opin Nephrol Hypertens. 19(1):59-64. Review.
  • Snelgrove RJ, Jackson PL, Hardison MT, Noerager BD, Kinloch A, Gaggar A, Shastry S, Rowe SM, Shim YM, Hussell T, Blalock JE. (2010) A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation. Science. 330(6000):90-94. PMCID: PMC3072752.
  • Thomson SC, Blantz RC. (2010) A new role for charge of the glomerular capillary membrane. J Am Soc Nephrol. 21(12):2011-2013. Review.
  • Vallon V, Sharma K. (2010) Sodium-glucose transport: role in diabetes mellitus and potential clinical implications. Curr Opin Nephrol Hyperten. 19(5):425-431. Review.
  • Zhou J, Ouyang X, Cui X, Schoeb TR, Smythies LE, Johnson MR, Guay-Woodford LM, Chapman AB, Mrug M. (2010) Renal CD14 expression correlates with the progression of cystic kidney disease. Kidney Int. 78(6):550-560. PMCID: PMC3422025.
2009

  • Arndt MA, Battaglia V, Parisi E, Lortie MJ, Isome M, Baskerville C, Pizzo DP, Ientile R, Colombatto S, Toninello A, Satriano J. (2009) The arginine metabolite agmatine protects mitochondrial function and confers resistance to cellular apoptosis. Am J Physiol Cell Physiol. 296(6):C1411-C1419. PMCID: PMC2692420.
  • Bolisetty S, Agarwal A. (2009) Neutrophils and acute kidney injury: Not neutral any more. Kidney Int. 75(7):674-676. Review.
  • Bouchard J, Mehta RL. (2009) Volume management in continuous renal replacement therapy. Semin Dial. 22(2):146-150. Review.
  • Bouchard J, Mehta RL. (2009) Fluid accumulation and acute kidney injury: consequence or cause. Curr Opin Crit Care. 15(6):509-513. Review.
  • Chen B, Guo L, Fan C, Bolisetty S, Joseph R, Wright MM, Agarwal A, George J. (2009) Carbon monoxide rescues heme oxygenase-1 deficient mice from arterial thrombosis in allogenic aortic transplantation. Am J Pathol. 175(1):422-429. PMCID: PMC2708827.
  • Chen Y, Mahata M, Rao F, Khandrika S, Courel M, Fung MM, Zhang K, Stridsberg M, Ziegler MG, Hamilton BA, Lipkowitz MS, Taupenot L, Nievergelt C, Mahata SK, O’Connor DT. (2009) Chromogranin A Regulates Renal Function by Triggering Weibel-Palade Body Exocytosis. J Amer Soc Nephrol. 20(7):1623-1632. Topic of editorial. PMCID: PMC2709688.
  • Cui X, Zhou J, Qiu J, Johnson MR, Mrug M. (2009) Validation of endogenous internal real-time PCR controls in renal tissues. Am J Nephrol. 30(5):413-417. PMCID: PMC2818397
  • Deng A, Tang T, Singh P, Wang C, Satriano J, Thomson S, Blantz RC. (2009) Regulation of oxygen utilization by angiotensin II in chronic kidney disease. Kidney Int. 75:197-204. PMCID: PMC3151651.
  • Friese RS, Rao F, Khandrika S, Thomas BG, Ziegler MG, Schmid-Schonbein GW, O'Connor DT. (2009) Matrix metalloproteinases: Discrete elevations in essential hypertension and hypertensive end-stage renal disease. Clin Exp Hypertens. 31(7):521-533. PMCID: PMC2875383.
  • Fung MM, Chen Y, Lipkowitz MS, Salem RM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Brophy VH, O’Connor DT, for the AASK co-investigators. (2009) Adrenergic Beta-1 Receptor Genetic Variation Predicts Longitudinal Rate Of GFR Decline In Hypertensive Nephrosclerosis. Nephrol Dial Transplant. 24(12):3677-3686. PMCID: PMC2790952.
  • Fung MM, O'Connor DT. (2009) Complex renal traits: role of adrenergic genetic polymorphism. J Am Soc Nephrol. 20(6):1172-1174. Review.
  • Fung MM, Rana BK, Tang CM, Shiina T, Nievergelt C, Rao F, Salem RM, Waalen J, Ziegler MG, Insel PA, O’Connor DT. (2009) Dopamine D1 Receptor (DRD1) Genetic Polymorphism G-94A: Pleiotropic Effects On Heritable Renal Traits. Kidney Int. 76(10):1070–1080. PMCID: PMC2803094.
  • Hill BG, Reily C, Oh JY, Johnson MS, Landar A. (2009) Methods for the determination and quantification of the reactive thiol proteome. Free Radic Biol Med. 47(6):675-683. PMCID: PMC2759107.
  • Khosla N, Soroko SB, Chertow GM, Himmelfarb J, Ikizler TA, Paganini E, Mehta RL. (2009) Preexisting Chronic Kidney Disease: A potential for improved outcomes from acute kidney injury. Clin J Am Soc Nephrol. 4(12):1914-1919. PMCID: PMC2798877
  • Lang F, Artunc F, Vallon V. (2009) The physiological impact of the serum and glucocorticoid-inducible kinase SGK1. Curr Opin Nephrol Hypertens. 18(5):439-448. PMCID: PMC2883450.
  • Lortie M, Bark S, Blantz R, Hook V. (2009) Detecting low abundance vasoactive peptides in plasma; progress towards absolute quantitation using nano LC-MS. Anal Biochem. 394(2):164-170. PMCID: PMC2745394.
  • Macedo E, Bouchard J, Mehta RL. (2009) Renal replacement therapy for acute renal failure. Minerva Urol Nefrol. 61(3):189-204. Review
  • Macedo E, Mehta RL. (2009) Prerenal failure: from old concepts to new paradigms. Curr Opin Crit Care. 15(6):467-473. Review.
  • Marrie RA, Cutter G. (2009) Relapses in multiple sclerosis: important or not? Neurology. 73(20):1612-1613.
  • Marrie RA, Cutter G, Tyry T, Vollmer T. (2009) A cross-sectional study of bone health in multiple sclerosis. Neurology. 73(17):1394-1398. PMCID: PMC2769555.
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2008

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