Special Stains

Pathology Histopathology Special Stains

Special Stains



Special stains (histochemical methods) are used to help visualize and/or identify structures and substances in sections. CPL can provide most standard special stains. Listed below are a few examples.

Acid fast stains (various methods) for mycobacteria [Mycobacterium avium, lung, mouse]
Congo red for amyloid [Islet amyloid, macaque (polaroscopy)]
Gram stains (various methods) for bacteria [Corynebacterium bovis, skin, nude mouse]
Grocott’s methenamine silver (GMS) for fungi [Pneumocystis carinii, lung, Rag2-/- mouse]
Jones methenamine silver for basement membrane and mesangium [Glomerulonephritis, mouse]
Luxol fast blue-PAS for demyelination [Demyelinating myelitis, mouse]
Masson’s trichrome for collagen & muscle [Renal arteritis, mouse]
Periodic acid-Schiff (PAS) [Hypersensitivity bronchitis, mouse (PAS-hematoxylin)]
Phosphotungstic acid-hematoxylin (PTAH) for fibrin [Glomerular thrombosis, mouse]
Prussian blue for ferric iron [Hemosiderin, spleen, mouse]
Sudan black for lipids & lipochrome pigments [Lipochrome pigment, heart, ruffed lemur]
Verhoeff's method for elastin [Renal arteritis, mouse]
Warthin-Starry method for bacteria [Helicobacter hepaticus, liver, mouse]

Additional News and Announcements

  • Office of Sponsored Programs Announcement - New Website Launch

    The Office of Sponsored Programs is pleased to announce the launch of our new OSP website. The new OSP website offers users a more efficient navigational design structure with enhanced content categories.

    Enhancements include:

    • Improved Search - Utilizing the search field found at the top right corner of every page on our site now yields more accurate, more relevant results, helping you find desired content easily and quickly.
    • Improved Quicklinks - Visitors can now immediately jump to desired content from our home page through the creation of an improved Quicklinks menu that links to our most demanded/visited pages based on page-view statistics.
    • Featured Pages - The website will now periodically feature pages promoting higher awareness of existing content or new content. This reinforces our commitment to providing users with effective knowledge, resources, and tools.

    For more information about changes to the new OSP website, please visit our welcome page. If you currently have forms or pages from our existing website bookmarked, these links should be automatically redirected to the new the website content. 

    For additional information, please contact Mike Matthews at mimatt@uab.edu or Jonathan Price at jonprice@uab.edu.

    Posted by Office of Sponsored Programs | 04/21/16
  • Center for Disability Health and Rehabilitation Science Guest Lecturer: Dr. Robert Motl

    Center for Center for Disability Health and Rehabilitation Science presents

    Professor Robert W. Motl, PhD
    Department of Kinesiology and Community Health Neuroscience Program
    University of Illinois at Urbana - Champaign: 

    Physical Activity and Multiple Sclerosis - What We’ve Learned and Where We Need To Go

    Thursday, April 14, 2016 12:00-1 p.m.
    School of Health Professions Building Executive Learning Center, Room 640

    Bring Your Lunch

    Beverages will be provided

    To RSVP, please contact Jane Moore at (205) 934-5909 or Email: djmoore@uab.edu  no later than Noon Wednesday 4/13

    Posted by Center for Disability Health and Rehabilitation Science | 04/12/16
  • Call for Abstracts: 7th Annual UAB Diabetes Research Day

    ​Registration is now open for the 7th Annual UAB Diabetes Research Day to be held on May 3, 2016 at the Doubletree Hotel.  Please join us for this event where researchers from across campus and other institutions present their diabetes related research via oral presentations and poster presentations.

    Abstracts Due Monday, April 11, 2016.

    Abstract Guidelines:
    For abstract submission, please include a title, the full name of all authors, affiliations (Division, Department, University) and underline the presenting author’s name. The body of the abstract should be less than 250 words. Please use Arial 11 font for all text. Email abstracts in a word file to mpreuss@uab.edu. If you are a trainee/staff, please copy your PI on the abstract submission.
     
    There is no cost for attendance, but registration is required to reserve lunch. Please register by April 25th!
    Posted by Comprehensive Diabetes Center | 04/06/16
  • NIH eSubmission Items of Interest - March 25, 2016

    The NIH Grants and Funding website has been redesigned and simplified with a video tour available. FORMS-D Application Instructions are now available. FORMS-D Application Packages are now available for some FOAs. FORMS-C should be used for applications with due dates on or before May 24, 2016. FORMS-D should be used for applications with due dates on or after May 25, 2016.
    Posted by Office of Sponsored Programs | 03/25/16
  • NIH eSubmission Items of Interest - February 29, 2016

    NIH eSubmissions Items of Interest for February 29, 2016. FORMS-D application changes are on the way. FORMS-D must be used for applications with due dates on March 25, 2016 or after. Read full article for a preview of FORMS-D and guidance on determining when and how to use FORMS-D.
    Posted by Office of Sponsored Programs | 03/01/16
  • Reminder Regarding ASSIST Grant Applications

    As the February 5th deadline for new NIH R01 submissions approaches, OSP would like to remind you that all competing, single-project NIH grant applications can now be submitted through ASSIST.
    Posted by Office of Sponsored Programs | 01/25/16
  • Request for Nominations for Director of the Center for Structural Biology (CSB)

    ​The UAB CSB Internal Search Committee invites nominations of UAB faculty members for the position of Director of the Center for Structural Biology (CSB).  The CSB was established in 2011, and is one of 24 University-wide Interdisciplinary Research Centers (UWIRCs); it has been led by Lawrence J. DeLucas, Ph.D., since its inception.  The mission of the Center for Structural Biology is to support research and education through exploration of structure/function relationships for biological macromolecules and the development of novel technologies for biomedical research which enhance UAB’s basic and translational research goals.  Center membership includes more than 125 faculty and non-faculty members and hosts a number of on-site core facilities, as well as access to a national laboratory x-ray beam.
     
    The Director will oversee all of the interdisciplinary center activities, be a member of the Council of Center Directors and be responsible for interfacing with participating schools and managing the budget.  Nominations, including self-nominations, should include a CV and a one (1) page summary outlining the qualifications of the proposed Director and summarizing ideas and plans if appointed to the position.  The decision will be made after review and interviews by the Search Committee.
     
    Nominations should be submitted to Jamie Seitz (jbseitz@uab.edu) by Friday, January 29, 2016. 
    Posted by Office of the Vice President for Research and Economic Development | 01/19/16
  • MTO Change in Process for Finalized Agreement Documents

    The Material Transfer Office is changing the process for providing finalized agreements to the campus. Previously the finalized documents were emailed to the investigator, now the investigator will be notified that the finalized agreement is available for viewing through an eReport.

    Details can be found on the IRAP Website.

    Posted by Office of the Vice President for Research and Economic Development | 12/10/15
  • UAB Institutional Signing Official Change Effective November 9, 2015

    Effective Monday, November 9, 2015, please use the following name and title on all OSP submissions for external sponsors requiring the name of the UAB Institutional Signing Official:
    Richard B. Marchase, Ph.D.
    Vice President for Research and Economic Development
     The remaining contact information, address, email and phone numbers, should remain the same:
    Address:
    AB 1170
    1720 2nd Avenue South
    Birmingham, AL   35294-0111
    Email:  osp@uab.edu
    Phone:  205.934.5266
    Fax:  205-975-5977

    Any submissions in progress, in route or received by the OSP, will be updated to reflect the correct signing official.

    If you have any questions please contact the OSP at askosp@uab.edu.

    Posted by Office of Sponsored Programs | 11/05/15
  • Research Infrastracture Update

    IRAP - the Integrated Research Administration Portal - is an electronic tool that uses interconnected software modules to enhance each phase of the research process at UAB, from alerting investigators to new funding opportunities with the SPIN and SMARTS modules, to facilitating transfer agreements on research materials. Many documents can be shared across modules, eliminating the need to fill out redundant forms. Significantly, IRAP’s battery of more than 130 reports gives investigators granular data on the status of their submissions, so they always know where they are in the process. IRAP also allows administrators to improve workflows and procedures by finding and fixing bottlenecks in the system. In turn, this helps Research Administration offices work to deliver a better customer experience and to focus on improving customer service overall.
    Posted by Office of the Vice President for Research and Economic Development | 10/30/15
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