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CCTS Impact - Research Success Stories

A single study can ripple far beyond the lab, leading to new diagnostics, treatments, or clinical practices that change how care is delivered. These stories trace that journey, from a CCTS-supported research question to a tangible outcome that improves patient care.
CCTS ImpactProgram Success StoriesEntrepreneurship StoriesIndividual Career Stories

CHAP Trial Shows Early Blood Pressure Control Saves Lives in Pregnancy

CHAP Trial Shows Early Blood Pressure Control Saves Lives in Pregnancy

The landmark CHAP Trial evaluated active antihypertensive treatment in 2,408 pregnant women with mild chronic hypertension, proving that keeping blood pressure below 140/90 mm Hg significantly reduces major adverse pregnancy outcomes, preeclampsia, and preterm births without impacting fetal growth—a practice-changing finding that transformed national ACOG guidelines and clinical care standards.

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Nerves Fuel Breast Cancer Metastasis Through Mitochondrial Transfer

Nerves Fuel Breast Cancer Metastasis Through Mitochondrial Transfer

Researchers discovered that nearby neurons can transfer mitochondria to breast cancer cells, boosting their energy supply and metastatic potential while revealing a promising new target for therapies designed to disrupt this tumor–nerve connection.

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