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In Type 1 diabetes, verapamil prevents decline of IGF-1 and promotes beta-cell IGF-1 signalingThese results add an additional, mechanistic aspect to further explain how the decades-old blood pressure medication verapamil can preserve beta cell function in Type 1 diabetes patients by affecting the hormone insulin-like growth factor 1.
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Type 1 diabetes: first clinical trial of GABA/GAD in newly diagnosed, very young childrenThe clinical trial focused on very young children, who have a more rapid loss of the pancreatic beta cells than do adolescents. The trial was constrained to a low-dose level, but showed safety and tolerability and reduced serum glucagon, a secondary outcome.
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Type 1 diabetes: Maintaining the enzyme ACE2 in the gut prevents diabetic blindnessDiabetic retinopathy is the leading cause of blindness in American adults. The source of this damage may lie in the belly — mainly a leaky small intestine. A novel treatment can possibly prevent or reverse this damage.
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Coaching, food delivery and more: A new diabetes management study will soon enroll patientsThis study will enroll patients to evaluate which combination of three proposed interventions — including health coaching, food delivery and remote patient monitoring — will help patients manage diabetes and also be sustainable for health systems to implement.
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