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Lung-resident memory B cells produced during influenza are long-living immune cells that migrate to the lungs from draining lymph nodes and lie in wait as early responders that can quickly react to future infections. They are key sentinels against subsequent[…]
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The study, funded by the Patient-Centered Outcomes Research Institute, will compare two pathways of post-fracture patient care.
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$46 million awarded by NIH to UAB and partners allows researchers to continue following participants enrolled in the national Multicenter Osteoarthritis Study.
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Flash radiation therapy delivers an ultra-fast, ultra-high burst that has the same deadly effect on tumors with fewer side effects for patients.
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Using machines at UAB Libraries or in their own units, staff, students and faculty are making tools for their research projects, classrooms and HVAC units campuswide. See their work and find out how you can get started.
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Knowledge of this previously unrecognized mechanism may aid therapy for patients with interleukin-6 signaling mutations and hyper-IgE Syndrome, or HIES.
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Description of this mechanism offers a promising therapeutic target to limit lung injury and death. Lower respiratory tract infections, including bacterial pneumonia, are the fourth-leading cause of death worldwide, with 120 million to 156 million cases and 1.4 million deaths[…]
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These effector memory B cells appear poised for a rapid serum antibody response upon secondary challenge one year later, and evidence shows that the cells in this subset differ from all previously described memory B cell subsets.
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The University of Alabama System Board of Trustees voted to appoint one chair and three professors to endowed positions during its Feb. 3 meeting. Those honored are Jeffery Walker, Lewis Shi, Farah Lubin and Brant Wagener.
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Dr. Ken Saag, 2022 ACR PresidentKen Saag, MD, MSc, delivered a stirring presidential address at the American College of Rheumatology annual meeting in October 2022. While COVID-19 continues to pose special risks to immunocompromised patients, he said, it is beginning[…]
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Megan Leask, Ph.D., InstructorMegan Leask, Ph.D., has received an NIH/NIAMS Competitive Diversity Supplement for an existing R01 awarded to Dr. Richard Reynolds for her research titled, "Functional and Integrative OMICS of Recurrent Gout Flares.” Leask is Indigenous Māori from New[…]
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Dr. Jasvinder Singh, senior authorMany genome-wide association studies (GWAS) have begun the work of identifying genetic loci of osteoarthritis. This study, comprised of 484,374 participants from diverse ancestries and ethnicities, is a major step toward addressing the underrepresentation of non-European[…]
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Kenneth Saag, M.D., Msc, delivering the Presidential Address at the 2022 American College of Rheumatology Annual MeetingThe UAB Division of Clinical Immunology and Rheumatology has been ranked among the best in the nation by the U.S. News & World Report[…]
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One UAB patient uses her transformational story to spread awareness of scleroderma.
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U.S. News & World report named UAB Hospital as the best hospital in Alabama.
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UAB rheumatologists will begin seeing patients at the UAB Hoover Primary Care clinic in July 2022.
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As part of a study funded by Pfizer, Inc., UAB will partner with Whitfield Hospital in Demopolis and John Paul Jones Hospital in Camden to evaluate how thermography cameras can improve telemedicine visits for arthritis patients in rural Alabama.
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The UAB Faculty Development Grant Program supports junior faculty with funding to pursue research, creative works and scholarly activity.
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Blacks face much greater rates of heart disease than do whites. A wider study is needed to further investigate this racial difference and identify potential therapeutic targets.
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Dr. Jeffrey Curtis wants to use virtual reality to help patients with rheumatoid arthritis experience how the disease may worsen over time in the future to improve shared decision making about their treatment choices in the present.
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How can physicians help patients with rheumatoid arthritis when methotrexate fails? It was hoped that a new class of oral medication held the answer, but the FDA issued a black box warning for JAK inhibitors last year citing major adverse[…]
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Maria I. Danila, MD, MSc, MSPH Our understanding of how to best use telemedicine for rheumatology patients began with our need to care for patients with chronic illness during the height of the COVID pandemic.
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The American College of Rheumatology is the premier society for the advancement of rheumatology in the U.S. This year’s ACR President, a newly designated Master, and a Distinguished Fellow all call UAB home.
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A detailed mechanistic study unravels how the bacterial endotoxin LPS prevents or promotes allergic disease.
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Lupus, an autoimmune disease that can attack any part of the body, can be confounding because patients often respond differently to the same treatment, and they vary widely in the severity of their symptoms.
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Record $95 million Heersink lead gift to advance strategic growth and biomedical innovation.
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This finding upends the long-held paradigm that priming during lung infections takes place only in the draining lymph nodes, and it will be key to developing more efficient vaccinations and therapies for respiratory challenges.
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Intranasal vaccination is needle-free and elicits immunity at the site of infection, the respiratory tract.
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The COVID-19 pandemic highlighted the urgent need for enhanced study and discovery in the field of immunology.
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This year, the university recognizes 50 years of service by Jeanne Hutchison, Ph.D., and Ferdinand Urthaler, M.D., and 45 years of service by Robert Kim M.D., and Joseph Lovetto. In addition, 294 employees with 20 or more years and 904[…]
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Associate Professor Maria Danila, MD, MSc, MSPH has received an Innovative Research Award from the Rheumatology Research Foundation. She will investigate how increased tele-rheumatology due to COVID-19 impacts the health outcomes of patients with rheumatic and musculoskeletal diseases.
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Dr. Tony MerrimanProfessor Tony Merriman, PhD, FRSNZ, joins our faculty from the University of Otago in New Zealand. Dr. Merriman is an internationally recognized scientist and leader in the genetic basis of gout and rheumatoid arthritis. Dr. Merriman's research interests[…]
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Dr. Troy Randall with cytometry equipment. The idea that cells are the unit of life began when Dutch scientist Antonie van Leeuwenhoek looked under a microscope. He was the first to observe that tissues were composed of tiny chambers—cells—that worked[…]
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According to a 2019 Pew Research Study, about one in five U.S. adults regularly wears a smart watch or wearable fitness tracker. This trend is producing a wealth of health data that can be leveraged to improve medial practice and scientific[…]
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Each year, UAB’s official photographers capture tens of thousands of images as they document the incredible variety of events and personalities that make up our community. Here are some of our favorite photos of some of the most dramatic months[…]
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The study is funded by the Patient-Centered Outcomes Research Institute.
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A recent grant to UAB researchers from a national organization will yield insight into telehealth and potentially increase patient access to rheumatic care.
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A new multidisciplinary program within UAB Medicine will help evaluate patients who have recovered from COVID-19 but are still experiencing symptoms and link them to the specialized care they need.
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The vaccine candidate Altimmune’s AdCOVID potently stimulated neutralizing antibody and T cell responses, as well as mucosal immunity in the respiratory tract.
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A long time UAB rheumatologist has been named director of division in the UAB School of Medicine.
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Women who had total body irradiation to prepare for blood or marrow transplantation before age 30 had a 4.5-fold increase in their risk of developing breast cancer later in life.
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Bridges will serve a two-year term as president of a specialty research foundation.
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Unsuspected genetic variation among strains of mice can surreptitiously confound data results.
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Investigators attract major grants to use AI on failed drug trials, cell-free DNA and puzzling CT scans.
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We are delighted to welcome Amanda Schnell, MD, to the Division. Dr. Schnell has been appointed Assistant Professor of Medicine and will see patients in the Rheumatology Clinic at The Kirklin Clinic. As a clinician-educator, Dr. Schnell brings both compassion[…]
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UAB is helping develop automated technology to assess joint damage from rheumatoid arthritis.
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Maggie Guthrie, MD, Lesley Jackson, MD, Amanda Schnell, MD, Kenneth G. Saag, MD, MSc, Courtney Crayne, MD, Nitasha Khullar, MD, and S. Louis Bridges, Jr., MD, Ph.D. were part of group of more than 100 patient advocates and individuals from The[…]
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This study included preclinical experiments and use of bronchoalveolar cells from IPF patients.
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Cooper spent 40 years at UAB, where he made countless discoveries in immunology.
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These preclinical findings may have therapeutic potential for autoimmune diseases like lupus.