Research - News
This transport system may be widespread across many Gram-positive bacteria that contain proteins in the WXG100 superfamily. Tuberculosis kills 1 million people each year.
Differences in DNA methylation correlated with differences in heart-failure outcomes, as measured by two-year mortality.
Using spatial transcriptomics, UAB researchers set out to understand the differences and similarities between two viral infections causing acute lung injury, as it could improve patient care, as well as identify novel therapeutic targets.
Heart failure is a leading cause of death in the United States. Highly effective medications are now available, and the disease is manageable if patients seek care and take their prescribed medications regularly.
A study conducted by UAB investigators found that the newly recommended scores are very effective in diagnosing a type of heart failure that is challenging to detect, and can also help predict patients’ long-term outcomes.
This study will aid the understanding of, and future research on, inflammatory bowel disease, which afflicts about 1.6 million Americans. 
Many patients have been struggling to pay for their treatment, and the financial consequences can affect a person’s emotional well-being. This collaborative effort will recruit researchers nationwide to help solve these issues.
In a study of more than 6,000 American adults, UAB investigators found that those with a coronary artery calcium score greater than zero have a higher risk of cardiac events. CAC may help guide blood pressure control and comprehensive cardiovascular care.
Researchers find a role for citrullinated vimentin as a damage-associated molecular pattern molecule, or DAMP, that is generated by lung macrophages in response to environmental cadmium/carbon black.
After a pause due to COVID-19, UAB has resumed enrollment for the All of Us Research Project.
The study points to an adhesive cell surface protein that might be a key element in tackling the resistance to radiation therapy commonly seen in glioblastoma tumors.
Alabama and the Southeast have high rates of kidney disease, especially in minority populations. On World Kidney Day, physicians have a chance to shine a light on this troublesome disease.
Research funding to UAB from the National Institutes of Health tops $300 million again.
UAB researchers Jerzy Szaflarski, M.D., Ph.D., and Ayushe Sharma, Ph.D., won for their study of whether taking cannabidiol oil for seizures affects structures in the brain.
New research in mice points to a significant role for fungi to shape metabolism, including fat deposition, and metabolic hormones.
The COVID-19 pandemic has taken a toll on the mental health of emergency department staff, both clinical and non-clinical.
The list was made by a group that aspires to bolster and increase diversity across all scientific fields, promote retention through the “leaky academic pipeline,” and broaden academic and industrial awareness of diversity and inclusion.
Suzanne Judd, Ph.D., an epidemiologist at UAB, explains what will lead to herd immunity and why it is important to remain vigilant in reducing the spread of COVID-19.

Preclinical tests at UAB last year showed potent systemic and mucosal immune responses in mice after a single intranasal dose. The vaccine candidate was developed by Maryland-based Altimmune Inc.

To date, 33 percent of vaccine doses administered by UAB have gone to underrepresented communities, with almost 21 percent to Black Alabamians.
Innovation is widely regarded as one of the most important sources of sustainable competitive advantage in an increasingly changing environment.
Research found that gaining community members’ perspectives to identify barriers and facilitators to COVID-19, related to prevention, coping and testing, may potentially improve outcomes.
Altered epigenetic marks on ribosomal RNAs appear to create a pool of specialized ribosomes that can differentially regulate translation of specific messenger RNA.
In a new study from UAB, researchers found that eating grapes can protect skin from acute and chronic UV damage.
Ben McManus’ proposal to research the understudied relationship between resident well-being and work organization factors wins a distinguished NIOSH K01 grant.
PAGER-CoV offers a data-driven, precision medicine approach to help researchers around the world better understand COVID-19.
The 72-year-old patient was unable to mount her own immune defense against the SARS-CoV-2 virus because of chronic lymphocytic leukemia, which compromises normal immunity and immunoglobulin production.
If these hollow capsules are modified to target a solid tumor, PET imaging and therapeutic ultrasound can be used to rupture them and release an anticancer drug at ground zero.
The study highlights the common host genetic factors that influence the composition of the human gut microbiome, a major factor in human health.
Use of the diabetes drug metformin — before a diagnosis of COVID-19 — was associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes.
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