Research & Innovation
UAB’s exploratory Alzheimer’s Disease Research Center will address a coverage gap in the Deep South of the nation’s ADRC network.
These lipids may act as a biomarker for Type 1 diabetes and offer a therapeutic target to prevent the disease.
Uncontrolled high blood pressure is a risk factor for heart attack and stroke.
A UAB communications expert explains how communication skills have changed during the COVID-19 pandemic quarantine.
The UAB team identified how the poorly understood BIN1 gene might be player in Alzheimer’s disease.
In a new trial funded through UAB’s urgent COVID-19 research program, investigators are comparing the widely available steroid methylprednisolone with dexamethasone, which lowered risk of dying by one-third in a U.K. trial this summer.
A K23 grant from the National Institutes of Health will determine how to best improve growth in preterm infants.
A drug that inhibits the protease plasmin is hypothesized to reduce the infectivity and virulence of the virus, as measured by reduced need for hospitalization within a week.
Drs. Vickers and Pisu will use a $3 million, five-year National Institute on Minority Health and Health Disparities grant to study barriers that may exist for GI cancer patients to access quality cancer surgery in Alabama and Mississippi.
Low or limited health literacy is common among adults in the United States and may affect health outcomes in many ways, according to the government’s Healthy People 2020.
These potent CD4+ and CD8+ T-cell responses were stimulated in the lungs following a single intranasal administration.
Soft drink consumption is a likely predictor of aggressive behavior, according to a new study from UAB.
Amy Goss, Ph.D., RDN, says egg consumption can be incorporated into the diet in a healthful way without adversely impacting blood cholesterol in older adults.
UAB and Polish researchers propose that the COVID-19 virus acts as a microRNA “sponge” to deplete miRNA levels in ways that aid viral replication and stymie the host immune response.
This was the first study to evaluate the impact of exercise on objective sleep outcomes in persons with Parkinson’s disease.
This is the first comprehensive genomic study of cervical cancers in sub-Saharan Africa, with a focus on tumors from 212 Ugandan patients. The findings can lead to better treatments.
The pilot projects will yield payoffs down the road from the knowledge UAB researchers gain. Preliminary data from the pilots will form the basis for new grants and contracts, including pursuit of the $2 billion COVID-19 grant support being offered by the National Institutes of Health.
Women who had total body irradiation to prepare for blood or marrow transplantation before age 30 had a 4.5-fold increase in their risk of developing breast cancer later in life.
The two studies are part of a larger body of research attempting to solve the puzzle of racial disparities in pain.
A study conducted by UAB investigators shows that nearly a third of non-Hispanic Black young adults nationwide have hypertension, and the control of high blood pressure in all young adults is only 10 percent.
The drug candidate is a non-toxic small molecule that given orally effectively rescued mice from models of Type 1 and Type 2 diabetes.
This research offers fundamental insights about sensory thalamic subnetworks and will enable powerful new strategies to probe behavioral and perceptual functions of these distinct circuits.
When the I-20/59 corridor was dismantled and rebuilt over a 12-month period in 2019, it disrupted travel for more than 150,000 vehicles per day. UAB engineers are using data from that project to gain a better understanding of how drivers adapted.
The study will look at how the variability of different behaviors can affect quality of life.

AdCOVID stimulated both strong serum neutralizing activity and potent mucosal IgA immunity in the respiratory tract.

This work is a step forward in understanding early molecular changes that influence the development of addiction, and may have application to the role of similar gene programs that mediate other types of behavior, memory formation or neuropsychiatric disorders.

This study was done in mice and with a novel, tissue-engineered, three-dimensional breast cancer mimetic system.
This mouse study looked at a group of immune cells called innate-like B-1 B cells.
Genetic assessments can help predict the risk of common diseases, and UAB is part of a national study to better understand and implement polygenic risk scores
In partnership with community members, researchers at UAB created the first culturally based protocol for patients living with a serious illness or facing end-of-life care.
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