Research - News

Disruption of Blimp1 in regulatory T cells remodels the tumor microenvironment and augments the response to immunotherapy.

Although unproven, this novel sickle cell therapy serves as a potential cure. More measures need to be taken to determine long-term function and organ improvement.

Research outcomes from a newly funded study could aid in the development of novel therapeutic strategies for Alzheimer’s.
Zhang’s research compares clothing expenditures between boys versus girls using a rich, household-specific data set.
Research in animal models shows better formation of the fistulas, which are a lifeline for kidney failure patients as the connection site to dialysis machines.

At UAB, the company IN8bio Inc. is running a Phase I clinical trial to treat glioblastoma multiforme, the most aggressive type of cancer that originates in the brain.

The PPMI study is looking for biomarkers for Parkinson’s disease, which would help identify those at risk and track the progression of the disease.

UAB O’Neal Comprehensive Cancer Center, Morehouse School of Medicine and Tuskegee University collectively receive $18 million U54 grant from the National Cancer Institute.

After years of researching the SON gene, Erin Eun-Young Ahn, Ph.D., may have found the cause behind an extremely rare disease. 

Recent studies have shown that formal exercise training can help boost memory, and memory deficit is relatively common in people with epilepsy.

COERE awarded $500,000 to provide funds for research supplements to early-career physician-scientists whose research has been impacted by COVID-19.

Basic and translational research in this field aims to repair heart injury and prevent the heart failure that often follows a heart attack.

Bacteria use molecular machines to move proteins, including toxins, across cell membranes. M. tuberculosis, which kills more than 1 million people a year, uses the ESX-4 type VII secretion system to transports its potent exotoxin.

Nearly 100,000 people in the United States have AE-IPF, and approximately 30,000 to 40,000 new cases are found each year.

Could superheroes make children participate in more dangerous play time? A UAB graduate research assistant is conducting a study to see whether superheroes could be related to adolescent injuries.

The study concluded that participants were hesitant to receive the COVID-19 vaccine due to mistrust, fear and lack of information.

The largest registry of U.S. children with cancer who were diagnosed with COVID-19 found an increased risk of having severe infection and having their cancer therapy modified because of COVID, underscoring the urgency of vaccinations for these children, the authors say.

The Hugh Kaul Precision Medicine Institute will help build the interface of the Biomedical Data Translator, a “virtual brain” that will host all biomedical data in the world. 

NIH selects UAB and UA as research sites for a longitudinal study on child development since pregnancy. 

The 10-week trial will include meals provided by study investigators.

Young cancer survivors are at higher risk of developing subsequent HPV-related cancers than the general population, but less likely to receive the HPV vaccine. Findings from the first clinical trial of its kind support making HPV vaccination a routine part of oncologic care for all young cancer survivors, researchers say.

A research grant provides opportunity to develop next-generation devices with application in quantum metrology, low-energy consumption spintronics and optoelectronic applications.
CORD will develop educational modules for students in grades 4 through 6 in Perry County, Alabama, to equip students and their families with accurate information about COVID vaccines.
The partnership between UAB and Tuskegee will build a community of scientists committed to inclusive excellence.
A study conducted by UAB researchers found that using genetic information for choosing medical treatment after getting a heart stent reduces the risk of potentially fatal cardiovascular events.
UAB’s Julie Kanter, M.D., says statewide surveillance programs for sickle cell disease can help facilitate progress to improve outcomes.
Preclinical experiments show how to identify non-responding tumors and improve their response to immunotherapy, using two investigational new drugs that are permitted for human use. Physicians could immediately start investigational research in patients to test the effectiveness of this personalized approach.
About three-quarters of people were consistently honest, telling between zero and two lies per day. By contrast, a small subset of people averaged more than six lies per day and accounted for a sizable proportion of the lies, says researcher Timothy Levine, Ph.D.
The grant links researchers from different disciplines, institutions and locations to study basic mechanisms that contribute to Parkinson’s disease.
The effort led by UAB is projected to receive $17 million from NIH to support up to four years of patient follow-up.
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