Research - News
The world’s first clinical trial of Resuscitative Endovascular Balloon Occlusion of the Aorta found that patients treated with REBOA were more likely to die than those who did not undergo REBOA.
Researchers found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment. Most transplant failures occur in the first four weeks.
UAB researchers conducted a landmark study that established the reference intervals for natriuretic peptides — hormones that regulate a range of beneficial bodily functions — and revealed that natriuretic peptide deficiency increases the risk of cardiometabolic diseases.
Cong’s research indicates the increased vulnerability of older adults to climate change impacts while also highlighting their resilience capacity in the face of disasters, offering valuable insights for policy development and disaster preparedness.
Analysis of a survey of 18,041 people in rural KwaZulu-Natal revealed a discrepancy between the ability of the South African health system to respond to the health needs of people with communicable diseases and the health needs of people with non-communicable diseases.
This new grant will be used to develop a full-scale family of devices for inhaled nitric oxide delivery for patients with pulmonary hypertension that can be used in health care facilities and for at-home care.
The Blazer Bridge Fund is intended to identify and assist in the development of promising ideas, discoveries, innovations and/or technologies from UAB faculty and staff that have commercial potential. 
UAB researchers conducted a study in end-stage heart failure patients with cardiogenic shock that revealed that B-type natriuretic peptide levels were elevated in end-stage heart failure but did not predict clinical outcomes.
Lung-resident memory B cells produced during influenza are long-living immune cells that migrate to the lungs from draining lymph nodes and lie in wait as early responders that can quickly react to future infections. They are key sentinels against subsequent viral variants.
The M.D./Ph.D. student has since moved on to clinical studies, but the research into possible drugs to treat Alzheimer’s disease continues.
The modified mRNA — delivered after experimental heart attacks — transiently allows heart muscle cells to proliferate, leading to reduced infarct size and improved heart performance compared to untreated animals.
While preventive treatment with vigabatrin delayed the onset and prevalence of infantile spasms in TSC infants, it had no impact on focal seizures, drug-resistant epilepsy, or improvement of cognitive and behavioral scores at 24 months.
UAB researchers make a case for utilizing telehealth technologies in the care of injured rural patients stating that teletrauma can improve access to trauma care for rural patients.
The study’s findings provide valuable insights into the role of diet composition in Type 2 diabetes management.
Rachel Smith, Ph.D., professor in the UAB School of Engineering and principal investigator in the Neural Signal Processing and Modeling lab, was recently awarded multiple grants to fund research in seizure onset localization.
Since 1985, the Coronary Artery Risk Development in Young Adults study has examined the factors that contribute to the development of cardiovascular disease to better understand the natural history of cardiovascular disease over the adult life course.
These results add an additional, mechanistic aspect to further explain how the decades-old blood pressure medication verapamil can preserve beta cell function in Type 1 diabetes patients by affecting the hormone insulin-like growth factor 1.
This is the first direct evidence that resident microbiota can have a significant impact on the establishment and pathology of infection by two different human-specific pathogens.
TCE is a known environmental risk factor for parkinsonism. UAB researchers will evaluate whether T cell activation caused by TCE exposure leads to cognitive decline.
Some PD-1+CXCR5+CD4+ T cells will become germinal center-Tfh cells that are essential for B cells to become high-affinity antibody-producing cells. Others do not take that path, instead becoming memory T cells.
The new technology will allow for non-invasive assessments for dry eye disease and inform the development of new treatments.
Periodontal disease is one of the leading causes of tooth loss in adults and may be a risk factor in the development of Alzheimer’s disease.
In a mouse model, border-associated macrophages, not microglia, were essential for the neuroinflammation that precedes neurodegradation. Targeting this subset could be a disease-modifying therapy in neurodegenerative disease.
$46 million awarded by NIH to UAB and partners allows researchers to continue following participants enrolled in the national Multicenter Osteoarthritis Study.
The newly introduced kidney function equation has value in predicting heart failure comparable to the old equation but may reduce racial disparities by improving access to heart failure therapy among Black heart failure patients.
UAB is one of the seven institutions receiving multimillion renewal funding to advance its Cyber Corps program. The grant will support an integrated curriculum for training master’s students in both cybersecurity and artificial intelligence.
New research from UAB shows a possible link between poverty and a child’s possibility of having a relapse in their acute lymphoblastic leukemia.
Published results from two UAB studies found the duration of intermittent hypoxemia events and the presence and persistence of a patent ductus arteriosus after birth are two novel risk factors of BPD-PH in preterm infants.
The UAB study revealed that specific linguistic styles within influencer posts can enhance or diminish engagement with the content.
Earlier research suggests that the use of low-dose atropine drops plays a role in slowing the progression of myopia in children. However, new research co-led by experts in the UAB School of Optometry shows that may not be the case.
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