Clinical Trials

This is a paid research opportunity for adults who provide care for adult loved ones 45 years or older. We are actively recruiting for a research study to examine caregivers’ experiences and health outcomes. To be eligible, caregiver participants need to commit to providing care for their loved ones at least five hours weekly, and their loved ones need to be ages 45 and older. The study takes approximately 45 minutes to complete and can be completed via our online survey or over the phone with one of our trained research assistants. Participants will receive a $20 gift card for completing the study. The link to complete the study is: https://uab.co1.qualtrics.com/jfe/form/SV_bmAfy0dohaFEciG. For more information, please call and leave a voicemail for our research lab at (205) 975-9452, or email Wesley Browning at wbro9119@uab.edu, or Celine Atkins at gcat347@uab.edu.
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Is your child ages 4 or 5? If so, they may be eligible to participate in a study at the UAB Youth Safety Lab. This study is about superheroes and children’s play. It involves a 90-minute visit to our laboratory and involves no risk or invasive behaviors. During the visit, you complete questionnaires while your child participates in games with a research assistant. Your child will also be randomly assigned to dress up as either a superhero or a student in school. You and your child earn $40 and take home a special prize as a thank you for your time. For more information, and to see if you might be eligible to join, please contact (205) 934-4068 or email chmorgan@uab.edu.
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The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a research study to evaluate the effectiveness of an investigational drug to treat people with Type 2 Diabetes and obesity. To qualify, you must have Type 2 Diabetes, older than 18 years old, moderately overweight, diet-controlled or taking oral diabetes medications. Qualified participants will receive the study drug free of charge and compensation for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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Looking for individuals between the ages of 18-70 with a diagnosis of traumatic brain injury, spinal cord injury, spina bifida, cerebral palsy, stroke, Parkinson disease, or multiple sclerosis to participate in Movement-to-Music (M2M), a rhythmic-based exercise program provided entirely remotely from Lakeshore Foundation. You may be eligible if you have stable cardiovascular conditions and have not participated in a similar research study in the past 6 months. All equipment for completing the program and additional compensation provided. To learn more about this opportunity and if you are eligible, please call Lori Theriot at (205) 313-7455 or email m2mstudy@uab.edu.
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We are looking for adults with type 2 diabetes for a research study to see if eating large amounts of whole fruit can improve your blood sugar and reduce your need for diabetes medications. You may be eligible if you are 20-65 years old, overweight (BMI 27-45), diagnosed with type 2 diabetes within the last 6 years, and are not taking insulin. Participants will be provided with meals for 12 weeks, a high-speed Vita-Mix blender, and $1,375 for completing the study. Since this study is time-intensive, we are seeking only highly motivated and dedicated participants. If you are interested, please complete the brief electronic form at http://bit.ly/fruit_study. For more information, please contact Cody Hanick at chanick@uab.edu or (262) 923-0672.
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We are looking for adults with type 2 diabetes for an exciting research study to see whether meal timing and/or bright light therapy can improve your blood sugar, reset your body clock, and improve your overall health. You may be eligible if you have type 2 diabetes, are 30-80 years old, are not taking insulin, and usually wake up between 5:00 and 9:00 am. The main part of the study lasts 16 weeks and involves two overnight tests in our clinic, which can be done on weekends, if preferred. Participants will receive $2400 for completing the study. If you are interested, please complete the brief electronic form at http://bit.ly/clocksstudy to apply for the study. Or for more information, please contact Kimberly Armstead at CLOCKSSTUDY@uab.edu or 205-484-5633.
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We are looking for adults for an exciting research study to see whether meal timing can improve your blood sugar and your overall health. Participants will be randomly selected to either graze throughout the day, skip breakfast, or skip dinner for 8 weeks. You may be eligible if you are 30-70 years old, are overweight, are not taking diabetes medication, and wake up between 5:00 and 8:00 am regularly. Adults with prediabetes, blood sugar issues, or a family history of diabetes are encouraged to apply. This study involves two overnight tests in our clinic plus eating only food that we provide you. Participants will receive $1200 for completing the study and 8 weeks of meals, valued at a total of $2400. If you are interested, please visit https://bit.ly/mealtimingstudy to apply for the study. Or for more information, please contact Kimberly Armstead at mealtiming@uab.edu or 205 484-5633.

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Is your child in good health without Diabetes, Hypertension, Hyperlipidemia, Thyroid dysfunction, Autoimmune diseases, Moderate to Severe Intellectual disability, or Taking medications affecting? If so, your child may be eligible to participate in a research study at UAB. Compensation up to $140 for two visits, each visit lasting 5 hours. For more information, please call the UAB Office of Psychiatric Research at Call: 205-975-4207
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We are enrolling opioid users without a history of psychosis, endocrine diseases, inflammatory diseases, or autoimmune diseases. If you meet these criteria you may be eligible to participate in a research study. Compensation provided up to $80. For more information, please call the UAB Office of Psychiatric Research at 205-934-8336.
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Healthy men and women, ages 18 to 75, are needed for a study exploring the reason why individuals who have diabetes have an increased risk of forming a calcium oxalate kidney stone. The study involves consuming prepared meals over 4 days and collecting urine and blood. Compensation $130. Please phone Demond at 205-934- 5712 or email kidneystone@uabmc.edu, if you are interested.
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Individuals with a history of kidney stones, 18 – 75 yrs, are needed for a study exploring factors impacting oxalate metabolism in kidney stone formers. The study involves consuming prepared meals over 4 days and collecting urine and blood. Compensation $130. Please phone Demond at 205-934-5712 or email kidneystone@uabmc.edu, if you are interested.
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Major Depressive Disorder patients may be able to contribute to our understanding of depression. If you have Major Depressive Disorder (MDD) that hasn’t responded to anti-depressant medication, learn about this research study of an investigational drug for MDD. As part of their study participation, patients will be regularly evaluated and closely monitored by a team of medical professionals. To pre-qualify for this study, you must: be 18 to 65 years of age; have been diagnosed with MDD; be in a current depressive episode for at least 8 weeks but not more than 12 months; and have been taking an antidepressant medication for at least the last 8 weeks. Additional criteria will apply. All study-related visits, tests, and study drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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Get involved in a research study that aims to understand how chronic pain from knee osteoarthritis may change learning. We are looking for adults aged 40-65 with knee pain due to osteoarthritis who are willing to have their brains scanned during a learning procedure. The commitment to this study will last approximately 2 hours and include one telephone screen and one visit to UAB where you will fill out questionnaires and have your brain scanned with magnetic resonance imaging (MRI) during a learning task. If you are eligible to participate in this study, you will receive up to $50. We are also recruiting healthy controls with no chronic pain. If you are interested, please send a message to foamstudy.uab@gmail.com or call 205-234-1201.
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We are looking for Black or White women ages 65-75 with knee pain due to osteoarthritis, who are willing to follow a prepared diet for 6 weeks. The commitment to this study will last approximately 7 weeks and include 1 telephone screen, 2 visits to UAB where you will fill out questionnaires and have blood taken, 4 visits to UAB where you will fill out questionnaires and have pain assessed, and 3 meals and 2-3 snacks per day provided for 6 weeks. If interested, please contact the DIPPER study at dipperstudy@gmail.com or by calling 205-234-1201.
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Researchers at the Alabama Vaccine Research Clinic at UAB are looking for volunteers between the ages of 18 and 50 to participate in HIV vaccine research studies. Procedures include the collection of medical and sexual history, blood and urine samples for lab testing, and a physical exam. Additional tests, such as STI testing, electrocardiograms, pap smears, and pregnancy testing may also be required. Screening visit compensation is $20, with additional compensation earned for study participation. You cannot get HIV from the vaccine. For more information, please call 205-934-7492 or email avrc@uabmc.edu.
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Researchers in the School of Medicine are recruiting people from the general public age 18 years or older to participate in a research study. The study is one remote visit that consists of filling out questionnaires online. The purpose of the study is to examine the racial differences in sleep patterns as it relates to cigarette smoking and smoking dependence. Results from this study may help in designing better treatments for quitting smoking. If you are eligible and decide to enroll, this study will take approximately one hour to complete, and you will be compensated $40 for your time. To see if you qualify go to: https://bit.ly/3wjtT2F 
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If you are 18 years of age or older. Have tried at least 1 antidepressant medication. Are feeling sad, down, or hopeless. Are feeling guilty, tense, or irritable, and are in good physical health. You may be eligible to participate in a research study comparing medications with transcranial magnetic stimulation. You will receive compensation for your time. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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We are seeking volunteers for a research study looking at the role of dietary protein and resistance training in weight loss. The study will last approximately 12 months. Participants will participate in the State of Slim weight loss program and receive body composition scans and lab work at no charge. Participants will meet in virtual group classes on a weekly basis for 4 months and monthly virtual group classes for the remainder of the year. Participants will receive monetary stipends totaling $300 to reimburse for time and travel to study classes and study visits. You may qualify for this weight loss research study if you: Are 50 years old or older. Have obesity (BMI of 30-50 kg/m2 or 25-50 kg/m² if you use a wheelchair). Check your BMI at:http://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm. Are willing to participate in virtual group weight loss classes, follow the State of Slim diet and exercise recommendations, and complete five study visits over a 12-month period at the Lakeshore Foundation Campus. Please call 205-975-4113 or email reba0315@uab.edu if you are interested.
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We are seeking volunteers for a research study looking at the role of different components of a lifestyle intervention program in family medicine clinics. The study will last approximately 6 months. Participants will receive nutrition or exercise counseling and receive body composition scans and lab work at no charge. Participants will receive weekly counseling sessions for the first 2 months of the study, and bi-monthly counseling sessions for the remaining 4 months of the study. Participants will receive monetary stipends totaling $300 to reimburse for time and travel to study visits. You may qualify for this research study if you: Are 18-75 years old. Not pregnant or lactating. Have a BMI of ≥ 27 kg/m² - Check your BMI at:http://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm. Are willing to participate in regular counseling sessions and attend 4 study visits at UAB’s Family and Community Medicine clinic over the course of the 6-month study. Please call 205-975-4113 or email reba0315@uab.edu if you are interested.
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UAB Psychiatry is looking for healthy volunteers without any psychiatric illness to participate in a study called “Disrupted Social Preference in Early Psychosis." The main purpose of this research project is to gather information on the nature of problems in social information processing in persons with schizophrenia compared to community controls. You will be compensated $25/hour and up to $260 for your participation. If you are between 18 and 35, have no history of problematic drug or alcohol use for the past three months, and no history of neurological disorders or psychiatric problems, please text or call Jake and Andrew at (205)440-3568 or email our lab team at nlsb.uab@gmail.com for further information.
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African American men and women ages 50-65 needed for study on lifetime stress and brain functioning. We want to pay people who identify as African American/Black to help us see if stress and other lifestyle factors can protect their mental health and their brain health. This knowledge is especially important to understand as people face difficult situations and might be at risk for Alzheimer’s disease. All information collected will be kept confidential. The study involves two visits lasting 2-3 hours each, including one MRI at UAB Highlands Hospital. A check of $75 will be mailed to you at the end of the study. For more information, visit: http://immcdonough.people.ua.edu/participate.html or leave a voice message at 205-348-2808.
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The Neuroinflammation, Pain, and Fatigue Lab is looking for women ages 18-55 who have symptoms of Chronic Fatigue Syndrome, ME/CFS, for a 1.5-hour brain imaging study. We will obtain magnetic resonance images, MRI, of your brain for one hour. The brain scans are non-invasive and do not involve exposure to radiation or injection of contrast agents. There will also be questionnaires. The purpose of the study is to investigate whether patients with chronic fatigue have increased brain temperature compared to healthy people. If interested, please contact Indonesia Jordan at 205-289-8748, or email ijordan@uab.edu with your name and phone number.
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The Neuroinflammation, Pain, and Fatigue Lab at UAB is looking for women with Fibromyalgia, and women who are healthy and without pain. Participants will come to UAB for a 2-hour screening visit and a 9-hour (all-day) study session. During the study session, we will induce a temporary immune response and assess its effect on fibromyalgia symptoms, including pain and markers of immune activity. You will provide blood samples and undergo brain imaging before and after the immune activation procedure. You will be paid $650 for completing both visits. Participants must be: currently suffering from moderate to severe Fibromyalgia, or be a healthy female and ages 18-55, not pregnant or planning to become pregnant, without significant other medical conditions such as heart disease, not using any opioid medication, for example, Norco, Tramadol, Percocet. To participate, please contact Indonesia at 205-289-8748 or email ijordan@uab.edu.
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The Translational Research for Injury Prevention (TRIP) Lab is looking for teens aged 14-17 and one parent/guardian to participate in a study to help UAB researchers understand more about self-driving vehicles. Participation for eligible teens and parents will include a single appointment located on the UAB campus with several different activities including questionnaires, computer tasks, and driving in a driving simulator. Participants will also be asked to complete a series of at-home pre-appointment questionnaires. The in-person lab session associated with the study is expected to last no longer than 2 hours. Parents and teens will each be compensated $50 each for participation. COVID screenings and precautions will be performed. For more information or to see if you are eligible, please contact the UAB TRIP Lab at 205-975-9440 or triplab@uab.edu.
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The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a 78-week research study to evaluate the effectiveness of an investigational drug to treat diabetes. In this trial, you will receive either once-weekly Icodec injections or once daily Lantus injections. To qualify, you must be 18 years old or older and have type 2 diabetes. Qualified participants will receive study drug, EKGs, eye exams, and Physical Exams. There is no charge for participation. Compensation for time and travel may also be available. For more information, and to see if you might be eligible to join, please call (205) 975-8217 or email mcr90@uab.edu.
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The Neuroinflammation, Pain, and Fatigue Lab is looking for women with relapsing-remitting Multiple Sclerosis ages 18-65 for a brain imaging study. The study includes a phone interview and two visits to UAB hospital: one screening visit including blood draws, and one imaging visit, during which we will acquire Positron Emission Tomography (PET) and Magnetic Resonance Images (MRI) of your brain for one hour. PET imaging involves exposure to a small amount of radiation. There will also be questionnaires. You will be paid $400 for completing the study. The purpose of the study is to investigate whether patients with multiple sclerosis have increased brain inflammation compared to healthy people. If interested, please contact Chloe Jones at chloej@uab.edu or P: 205-434-1502, and leave your name and phone number.
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Recovering from COVID-19?Still have problems with confusion, slow thinking, or memory? If so, you may eligible to take part in a study testing a new form of cognitive training designed to improve how quickly you process information and perform daily activities. The study pays participants $20 per training session on average. The training program, which requires several visits to UAB, can be tailored to fit your schedule. If you are interested, please call 205-934-9768 or email stacemc@uab.edu.
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We are looking for African American and Caucasian males with chronic low back pain to participate in a study to examine racial differences in the experience of chronic low back pain. To participate in this study you must have low back pain for at least 3 months, between the ages 18-85 years old, receive medical services at UAB, free from serious medical conditions, and able to come to two testing sessions one week apart. Participants will receive up to $400 for completing the study. You may not be eligible to participate if you have significant health problems, or are taking certain medications. Please contact Tammie at tquinn@uab.edu or call 205-934-8743. Leave a short message with your name, number, and mention that you are interested in the ERASED study.
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We are looking for healthy individuals to participate in a study to examine the effects of buprenorphine and baclofen in humans. This pilot study will be used to gather initial evidence to assess the analgesic interaction, safety, acceptability, and feasibility of using buprenorphine and baclofen in humans before conducting a larger clinical trial to examine efficacy in patients. We will be giving participants a one-time low dose of a partial opioid agonist buprenorphine or baclofen. Participants will be required to attend two visits one week apart and asked to complete questionnaires, pain testing, and a blood draw. Participants will receive up to $150 for completing the study. You may not be eligible to participate if you have significant health problems, are pregnant, or are taking certain medications. Please contact Tammie at tquinn@uab.edu or call 205-934-8743. Leave a short message with your name, number, and mention that you are interested in the BACUP study.
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We are looking for individuals to participate in a study that aims to gain a better understanding of risk factors for insomnia in people with and without the human immunodeficiency virus (HIV) and to observe its effects on pain sensitivity and inflammation. This study will consist of several various in-person visits that span from 3 visits within an 8-day period, and if qualified for the second branch of this study, an additional 6 visits once a week for the following 6 weeks. During the visits, participants will be asked to complete a sleep interview, wear a sleep device overnight, answer questionnaires, as well as perform pain testing and blood draws. Participants will be compensated appropriately for their time. You may qualify if you have good or bad sleep and are above the age of 18. We are recruiting both individuals who are HIV positive and individuals who are HIV negative. Please contact Dyan at dywhite@uab.edu or call 205-934-8734. Leave a short message with your name, number, and mention that you are interested in the HIPPI study.
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The Better BP study is currently enrolling 660 adults to take part in a research study about how to measure blood pressure. We are seeking adults older than 19 years of age who are not currently taking medications for high blood pressure, have no history of cardiovascular disease or major arrhythmias, no known sleep apnea, and not known to be currently pregnant. Participants will be compensated $150 for completing four study visits in the UAB Hypertension Research Clinic located at the 19th Street Community Health Building. To confirm your eligibility for this study, please email bpstudy@uab.edu to schedule your telephone screening, which should take approximately 10 minutes.
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You could be eligible for a research study examining variations in blood pressure during the day and at night. This study involves 3 visits over two consecutive weeks. The last visit is a 30-hour stay at the UAB Sleep-Wake Disorders Clinic at UAB Hospital-Highlands where participants will wear a blood pressure monitor and provide saliva samples. Compensation will be provided at the end of the study. For more information, please email ggloston@uabmc.edu or leave a voicemail at 205-934-3367.
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This study is being done to assess how well individuals can modify walking patterns. If you qualify, we anticipate that your participation in the study will span a single study visit, with a total time commitment of 3 hours. You will be compensated for your time. Please e-mail Daniel Kuhman at dkuhman@uab.edu or contact him by phone at 205-934-0416 if you are interested.
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You may be eligible to participate in a UAB research study comparing medications if you are 18 years of age or older, in good physical health, and have tried at least one antidepressant medication. You must be in a current depressive episode, feeling sad, down, hopeless, guilty, tense, or irritable.  You will receive compensation for your time. Please call (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please call (205) 934-2484 or email lalexander@uabmc.edu for more information.
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Are you in good physical health? Are you Caucasian/white? Are you between the ages of 34 and 65? Have you never been diagnosed with a psychiatric condition? If so, you may be eligible to participate in a study requiring a one-time blood draw. Compensation provided. Please call (205) 934-2484 or email lalexander@uabmc.edu for more information.
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Heterosexual sexually active women ages 18-45 needed for study exploring how bacterial vaginosis (BV), the most common vaginal infection, occurs in women. If eligible, the study involves an anonymous survey, STD testing, and completion of twice-daily sexual/reproductive diaries, and self-collection of 3 twice daily vaginal swabs over an 8 week time period. Volunteers will be compensated $20 for screening, $25 for the enrollment visit, $20/week for drop-off of daily diaries and specimens (weeks 1-7), and $50 for the final weekly drop-off (week 8). Please call 205-934-8166 for more information.
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This study is being done to better understand sexual health in the transgender community. Eligible volunteers will be compensated. If interested, please call (205) 934-8166.
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If so, you may qualify for a research study being conducted at the University of Alabama Birmingham. We are seeking people between 45 and 85 years of age to participate in a study of brain and breathing treatments for arthritis pain. The study involves seven visits over a three-week period to the study center at the University of Alabama Birmingham, where clinical tests and brain stimulation treatment will be done, along with brain scanning. Participants will receive $350 for completing the study. If you are interested, please call the PROACT Study at 205-934-9614.
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There is a new study that will examine the impact of a particular type of intermittent fasting called time-restricted feeding on symptoms of MS, as well as risks of diabetes and high blood pressure in adults with relapsing-remitting MS. The purpose is to see if when you eat might be as important as what you eat. You may be eligible if you have relapsing-remitting Multiple Sclerosis, are between the ages of 18-64 years old, and can walk 25 feet with or without assistance. If you qualify, this study will last 8 weeks and offers an opportunity to be compensated for your participation. If you are interested in learning more about this study, or if have any questions, please contact the project coordinator, Kathryn Green, at 205-319-1424, or email our lab at HBDLab@uabmc.edu
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African American adults, ages 25 to 45 are needed to determine if the timing of salt intake affects blood pressure throughout the day. This study involves 12 visits over 8 weeks. Participants will be compensated for participation. You may not be eligible to participate if you have significant health problems, are pregnant, or are taking certain medications. Please contact Alexis at aelambert@uabmc.edu or call (205) 582-7761 if you are interested in learning more about this study.
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You may qualify for a bowel leakage research study if you are female, 18 years or older, and have had accidental bowel leakage for at least 6 months. For more information contact 205-934-5498. Compensation is provided.
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This study is being done to determine your balance ability and confidence while performing two tasks that challenge your balance. The first task involves walking at a range of speeds. The second task involves responding to disturbances to balance while standing. If you qualify, your participation in the study sessions will require 2 visits to the laboratory. Each visit will be no more than three hours. Your decision to participate in this study is completely voluntary. There will be no compensation fee to you for taking part in this study. Please e-mail Jutaluk Kongsuk, PT, MS, jutalukk@uab.edu or contact her at 978-3592 if you are interested.
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Volunteers needed for exercise and blood pressure study. You may be eligible to participate in a research study about the effects of exercise and Metoprolol, a blood pressure pill, on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasian with no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please email Dr. Vibhu Parcha at vparcha@uabmc.edu if you are interested.
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You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking sacubitril/valsartan or valsartan, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Vibhu Parcha, vparcha@uabmc.edu if you are interested.
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The Neuroinflammation, Pain, and Fatigue Lab is looking for women ages 18-55 who have symptoms of Chronic Fatigue Syndrome, ME/CFS, for a 1.5 hour brain imaging study. We will obtain magnetic resonance images, MRI, of your brain for one hour. The brain scans are non-invasive and do not involve exposure to radiation or injection of contrast agents. There will also be questionnaires. The purpose of the study is to investigate whether patients with chronic fatigue have increased brain temperature compared to healthy people. If interested, please contact Indonesia Jordan at 205-289-8748, or email ijordan@uab.edu with your name and phone number.
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The Neuroinflammation, Pain, and Fatigue Lab is looking for women ages 18-55 who have symptoms of Chronic Fatigue Syndrome, ME/CFS, for a 1.5 hour brain imaging study. We will obtain magnetic resonance images, MRI, of your brain for one hour. The brain scans are non-invasive and do not involve exposure to radiation or injection of contrast agents. There will also be questionnaires. The purpose of the study is to investigate whether patients with chronic fatigue have increased brain temperature compared to healthy people. If interested, please contact Indonesia Jordan at 205-289-8748, or email ijordan@uab.edu with your name and phone number.
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The purpose of this study is to help research scientists and physicians gain a better understanding of how the brain works as well as understand why some people respond well to drug treatment for mental disorders and why others do not. Participation involves 5 study visits over the course of 16 weeks with MRI scans of the brain, questionnaires and assessments related to daily and psychiatric functioning, and an optional blood sample. You will be compensated up to $400 for your participation. For more information and to see if you qualify please contact Lindsay McCormick at (205) 996-9813 or lkmccormick@uabmc.edu
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Healthy and obese African American adults ages 25 to 45 years old are needed to study the effect of the time of day of salt intake on changes in blood pressure during the day. You will not be able to participate if you have certain health problems, are pregnant, or use certain medications. Involves 12 visits over 8 weeks. Compensation provided. Contact Alex at 205-975-9743 or alexlm@uabmc.edu .
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You may be eligible to participate in this important study if you are female and 21 years of age or older, if you are experiencing urine leakage with the feeling of urgency, coughing, sneezing, or laughing. For more information, contact our research team at 205-934-5498. Compensation is provided.
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Researchers in the School of Medicine are recruiting smokers 18 years or older and under criminal justice supervision who smoke at least 5 cigarettes per day to participate in a smoking cessation study. The study is 9 months long and consists of 10 study appointments. You will only come to our office for the first study appointment that lasts 2-3 hours. The remaining 9 appointments will be completed over the phone and by email or text message with study staff and will last between 30-60 minutes each. Eligible participants receive 4 weekly smoking cessation counseling sessions and 12 weeks of nicotine replacement therapy medication (patches and lozenges) to use during the study. You can receive up to $440 for completing all 10 study visits plus a couple of incentive programs. You will be paid using UAB ClinCard, which is like a debit card that is loaded with your study payment after each study appointment is completed. For more information about our study, please call our research staff at 205-207-1586.
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If so, you could be eligible to participate in a new research study that aims to better understand the role of the immune system in fibromyalgia. The Neuroinflammation, Pain and Fatigue Lab at UAB is looking for women with Fibromyalgia, and women who are healthy and without pain. Participants will come to UAB for a 2-hour screening visit and a 9-hour (all-day) study session. During the study session, we will induce a temporary immune response and assess its effect on fibromyalgia symptoms, including pain and markers of immune activity. You will provide blood samples and undergo brain imaging before and after the immune activation procedure. You will be paid $650 for completing both visits. Participants must be: currently suffering from moderate to severe Fibromyalgia, or be a healthy female and ages 18-55, not pregnant or planning to become pregnant, without significant other medical conditions such as heart disease, not using any opioid medication, for example, Norco, Tramadol, Percocet. To participate, please contact Indonesia at 205-289-8748 or e-mail ijordan@uab.edu.

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Need participants for an asthma study: If you have asthma, are at least 18 years of age, haven’t had oral steroids in at least 4 weeks, and are willing to donate 30 mL of blood, equivalent to two tablespoons, please contact Dr. Prescott Atkinson at 205-999-7688 or email patkinson@peds.uab.edu
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Seeking participants for the effects of mood on attention study. Must be age 21 or older. Must be in good health. Attend one session and earn between $10 and $30. For more information please contact: Mood Study Researchers 205-975-7809 or Caitlin Clevenger, PhD 205-996-2452.
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You could be eligible to participate in a new research study that aims to better understand the role of the immune system in fibromyalgia. The Neuroinflammation, Pain, and Fatigue Lab at UAB is currently looking for healthy women. We will induce a temporary immune response and assess its effect on symptoms and markers of immune activity. Participants must be healthy, female and aged 45-55, not pregnant or currently planning to become pregnant, without any significant medical conditions such as heart disease, and not using any opioid medication. To find out more about this study, contact Indonesia at 205-289-8748 or ijordan@uab.edu. For further information regarding questions, concerns, or complaints about research, research-related injury, and questions about the rights of research participants, please call 1-866-860-3411.
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February 26, 2020

Do You Vape?

Researchers at UAB are recruiting vape users to study naturally occurring psychological States. Participants do not have to want to quit to participate. You will have the opportunity to be compensated more than $210 for your participation. For more information please call our research staff at (205) 996-0323.
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UAB is currently offering a no-cost research treatment program for those who want to stop using cocaine. This study combines medication and counseling treatment. If you use cocaine and would like to stop, please call UAB at (205) 975-7721.
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BAPS is a new Breast Cancer Recovery study opening at the O’Neal Comprehensive Cancer Center. As part of our focus on healthy recovery from cancer and its treatment, we try to offer programs that will support women in their recovery. We are studying a new program that is designed to help women find ways to be active and productive in all areas of life including managing work and employment, taking care of their home and family, and doing healthy activities such as exercise, leisure, hobbies, and socializing. The 9-session program happens over the telephone, at times that are convenient for you. If you would like to learn more about the study, please call 205-996-0384
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Researchers at the University of Alabama at Birmingham are conducting a study to investigate the effects of a supplement on fat content in the blood after a meal. If you are between the ages of 25-45, male, and overweight, you may be eligible to participate. Participation involves 3 study visits, consuming a supplement and meal, and acquiring measures related to body composition and other aspects of health. For more information please call (334) 750-9398 or email rushingk@uab.edu.
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Adult Volunteers Healthy adults ages 18 to 45 years old are needed to study the effect of supplemental phosphorus on the human metabolome. You will not be able to participate if you have certain health problems, are pregnant, or use chronic antacids or laxatives. Involves 4 visits (30 minutes each) over 6 weeks. Compensation provided. Alexandra 975-9743 or alexlm@uab.edu
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If you are 18-60 years old, have a BMI greater than or equal to 27 and do not have a history of binge-eating disorder, you may be eligible to participate. If eligible, you will receive up to $60 in compensation. This is a 4-visit, IRB-approved study sponsored by the UAB Department of Psychology, investigating a lifestyle weight-loss method that does not use dieting, exercise or active drugs. For more information, please call 205-598-7451.
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Researchers at the UAB are conducting a study to investigate how daily consumption of types of foods influences body weight and composition and other outcomes related to the risk of certain diseases. If you are age 18-50 you may be eligible to participate. Participation involves attending 5 study visits, consuming a food item daily for 30 days and acquiring measures related to body weight, body composition and glucose metabolism. You will be compensated for completing the study. For more information please call 205-975-4113.
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We are recruiting new moms who have had a baby within the past 6 to 10 weeks for PLUS –The Prevention of Lower Urinary Tract Symptoms Research Consortium. The study involves completing a survey, two bladder diaries and one clinic visit at The Kirklin Clinic. There is no cost for your participation and parking tickets for Kirklin Clinic will be validated. If eligible, you may receive up to $100 in compensation. To learn if you qualify, call 205-975-9959.
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The purpose of the Feed Me Study is to examine the naturally occurring bacteria in the gut of women and the impact these bacteria may have on weight loss. We are looking for women who are non-Hispanic black or non-Hispanic white. Generally healthy ages 19-65 and currently overweight. Participation involves eating study-provided meals only for 4 weeks, completing questionnaires, basic body measurements, and providing stool and blood samples. Meals provided at no cost to the participant and additional compensation is available. Contact the Feed Me Study at 205-934-1715 to learn more.
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We want to pay people who identify as African Americans to help us see if stress and other lifestyle factors can protect their mental health and their brain health. This knowledge is especially important to understand as people face difficult situations and might be at risk for Alzheimer’s disease. All information collected will be kept confidential. The study involves two visits lasting 2-3 hours each, including one MRI at UAB Highlands Hospital. A check of $75 will be mailed to you at the end of the study. For more information, visit: http://immcdonough.people.ua.edu/participate.html or leave a voice message at 205-348-2808.
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UAB Department of Nutrition Sciences is conducting a nutrition study looking at the effects of diet in adults with type 2 diabetes, high blood sugar, for less than 5 years. You may qualify if you are between the ages of 35-65, are African American or European American, are not using insulin, and are willing to travel to UAB for testing visits. Qualified participants will receive weekly groceries, personal health information, group support sessions with a Registered Dietitian, and monetary compensation for your time. For more information and to see if you qualify, please call 205-934-4386 or email LLG@uab.edu.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please contact (205) 934-2484
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Have you never been diagnosed with a psychiatric condition? If so, you may be eligible to participate in a study requiring a one-time blood draw. Compensation will be provided. For more information please contact (205) 934-2484.
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Our research team is currently conducting a clinical research study in women who have had recurrent Bacterial Vaginosis (BV). You must be 18-50 years old. Eligible participants will have multiple visits and will be compensated up to $250 upon completion of the study. To learn more about the study please call: (205) 934-8166
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The ROME study is designed to discover how exercise affects the gut microbiome and fatigue in breast cancer survivors. This study includes 10 weeks of supervised, individual exercise sessions with exercise specialists. The study is funded by the National Cancer Institute. Participants must be between the ages of 18 and 70 with a history of stage I, II or III breast cancer within the last five years. For more information, contact the Cancer Lifestyle Team at (205) 934-8821 or email moveforward@uab.edu. All information is confidential and participation is free.
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Help researchers at UAB have a better understanding of how the body changes with physical activity and be part of a national movement to discover exercise. We’re looking for men and women who are 18 years of age and older who have been cycling or weight lifting regularly for at least a year and have no history of diabetes or heart disease.  You will receive up to $1500 compensation for your time. If you would like to have the opportunity to participate in fitness testing and have study-related exams at UAB Center for Exercise Medicine, please call 205-996-3569 or email motrpac@uab.edu.
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Help researchers at UAB have a better understanding of how the body changes with physical activity. We’re looking for men and women who are 18 years of age and older who do not exercise regularly to participate in our MoTrPAC research study.  You will receive up to $1500 compensation for your time. If you would like to have the opportunity to participate in fitness testing and have study-related exams at UAB Center for Exercise Medicine, please call 205-996-3569 or email us at motrpac@uab.edu.
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Food Study Researchers at the University of Alabama at Birmingham (UAB) are conducting a study to investigate how daily consumption of types of foods influences body weight and composition, and other outcomes related to the risk of certain diseases. If you are between the ages of 18-50 you may be eligible to participate. Participation involves attending 5 study visits, consuming a food item daily for 30 days, and acquiring measures related to body weight, body composition, and glucose metabolism. You will be compensated for completing the study. For more information call: 205-975-4113. Enrollment is limited.
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The wisdom Study wants to apply modern medical science to breast cancer screening by determining if personalized screening is better than annual mammography and learning how to improve detection while reducing over-diagnosis and false-positive readings. Women ages 40-74, with no history of breast cancer or ductal carcinoma in situ (DCIS), are asked to join. Participation can mostly be done from home, and there are no additional medical visits outside routine visits required. Please register at www.wisdomstudy.org
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You may qualify for a non-invasive, in-home exercise study for bowel leakage. To qualify you must be female and 18 years of age or older. If you are interested please call 205-934.5498. Compensation provided.
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Postmenopausal women 55 years of age or older with vaginal atrophy needed. Participants must be willing to use vaginal estrogen cream for 8 weeks. If you are eligible, your participation will involve 2 visits to our clinic over an 8 week period. A physical examination will take place at the first visit and then again after 8 weeks. Participants will receive compensation up to $150 for completing the study as requested. For more information please call 205-996-7372. Or you can email us at kpnorris@uabmc.edu
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Healthy individuals ages 13 to 19 needed for brain imaging (MRI) study. The study includes two 2-hour sessions, one of which will include a 1-hour MRI scan. Participants will also complete questionnaires and cognitive tests. Compensation: $75. Contact: Cognition, Brain and Autism Lab PEERS study at (205) 996-9368.
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The Department of Neurology is seeking healthy controls for its Innate and Adaptive Immunity in Parkinson Disease. Enrollment involves 2 visits over a 3-6 week period. For more information please contact Allen Joop at 205-934-5954.
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Researchers from the UAB Epilepsy Center are looking for healthy adults to participate in an NIH funded research study using brain imaging. Participants who are 18 years or older, speak English as the primary language, in good general health with no history of neurological or psychiatric illness are needed. The study involves 1-2 visits to UAB Hospital Highlands and 1 visit to Auburn University. Financial compensation of $300 plus mileage to travel to Auburn will be provided. For more information please contact: 205-975-7851
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UAB is currently offering a no-cost research treatment program. This study combines medication and counseling treatment designed to help you quit smoking cigarettes. For the completion of 6 in-person visits, you will be compensated up to $285. We are recruiting participants over the next few years with open enrollment. For more information, please call the UAB School of Public Health at 205-975-7721.
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Looking for individuals between the ages of 18-70 with a diagnosis of traumatic brain injury, spinal cord injury, spina bifida, cerebral palsy, stroke, Parkinson disease, or multiple sclerosis to participate in Movement-to-Music (M2M), a rhythmic-based exercise program at Lakeshore Foundation. You may be eligible if you have stable cardiovascular conditions and have not participated in a similar research study in the past 6 months. Compensation provided. To learn more about this opportunity and if you are eligible, please call Lori Theriot (205) 313 - 7455 or email m2mstudy@uab.edu
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This research study will be investigating how adults detect lies. The study will involve one 3-hour visit to the Cognition, Brain, and Autism Research Laboratory where subjects will complete cognitive tests and watch and rate videotaped interviews. Subjects will be compensated $40 for their time. Participants must be native English speakers and between the ages of 18 and 30 years old. If interested, call the Cognition, Brain, and Autism Research Laboratory at (205) 934-0971 or email cbralab@uab.edu
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Volunteers needed for exercise and blood pressure study. You may be eligible to participate in a research study about the effects of exercise and Metoprolol, a blood pressure pill, on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasian with no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please email Dr. Vibhu Parcha at drparcha@uab.edu if you are interested.
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You may be eligible to participate in a research study about 24-hour rhythm of a protein in your blood. This protein is related to the heart. Eligible participants must be healthy men or women, African American or Caucasian and have no history of diabetes, heart problems or kidney problems. The study involves consuming prepared meals, wearing a blood pressure monitor for 24-hours, 24-hour inpatient stay, and collecting blood samples and urine samples. Participants will be compensated and meals will be provided at no cost. Please e-mail Dr. Vibhu Parcha, drparcha@uab.edu if you are interested.
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Are you 19-65 years of age and in good physical health? With a good childhood, without Physical, Sexual, or Emotional Abuse? If so, you may be eligible to participate in a research study. Compensation provided up to $120. For more information, please call UAB Office of Psychiatric Research at 934-8336
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The UAB Transportation Research and Injury Prevention (TRIP) laboratory is currently recruiting participants for a new study examining driving behaviors in adolescents and young adults with autism and with attention-deficit/hyperactivity disorder. Participants must be 16-30 years old, have a valid driver’s license, be a healthy volunteer or have one of the following diagnoses: autism spectrum disorder, attention-deficit/hyperactivity disorder, ASD/ADHD comorbid. Participants can earn up to $200 for participation. Interested participants should contact 205-975-9440 or visit triplaboratory.com to inquire about the “Transit” study.
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The purpose of this Phase II adaptive study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics of PF006730512 following multiple intravenous infusion in adult subjects with primary FSGS. You may qualify if you are a male or female ages 18-65, with an eGFR >45, a UPCR >1.5 g/g, also a non-responder to a single treatment regimen for FSGS, considered intolerant to an Immunosuppressant and are a non-responder to a single treatment regimen, or considered intolerant to an Immunosuppressant and are naïve to other Immunosuppressant treatment regimens for FSGS. Must discontinue steroid treatment or tapered down to a stable prednisone dose 7.5 mg per day or other steroid equivalents to achieve a stable dose before the lead-in period. Participants must be willing and able to comply with scheduled visits, must comply with birth control regimen or have proof of postmenopausal status. If you are interested please contact Teresa Chacana at (205) 934-7649
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The nefIgArd clinical research study is for patients diagnosed with primary IgA Nephropathy, IgAN, who are at risk of developing end-stage kidney disease even though they are taking medication to preserve kidney function. IgAN, also known as Berger’s disease, is a kidney disease where the antibody called immunoglobulin A, IgA, embeds itself into the kidneys. This causes inflammation, which can affect the kidney’s ability to filter the blood. Some cases of IgAN progress slowly without symptoms or go into remission, while others lead to end-stage kidney failure. Currently, there are no drugs approved specifically to treat IgAN. The purpose of the nefIgArd study is to look at the safety, tolerability, and effectiveness of the study drug Nefecon compared to placebo in patients with IgAN, who are at risk of progressing to end-stage kidney disease To learn more about study participation, contact: Ciara Mitchell at 205-975-9491.
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Researchers at the University of Alabama at Birmingham are recruiting for studies that examine the effects of Virtual Reality Walking on SCI pain experience. Participants receive between $350 to $400 dollars for study participation. Transportation is reimbursed. Participants must be between the ages of 18 and 65 and have complete paraplegic injury. If you are interested, call the Virtual Reality Walking Study at Dr. Trost’s Research Lab for more information. (205) 934 - 9040
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The Cognition, Brain, & Autism Lab is recruiting participants for a research study on reading comprehension at the University of Alabama at Birmingham. This study observes how children’s brains respond when they read and understand words and sentences, using a series of paper-pencil tests and a type of scan called functional magnetic resonance imaging also known as fMRI. We are recruiting children and adolescents between the ages of 7-13 diagnosed with high-functioning Autism Spectrum Disorder, children with reading comprehension difficulties, and typically developing children. Your child may be eligible for a free language intervention. Participants must be native English speakers and right-handed. Participants cannot be claustrophobic or have braces. If you are interested in participating, contact Maria Martino at (205)202-0616 or mmartino@uab.edu
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You may qualify to participate in an active-control treatment study of the efficacy and safety of Sparsentan, funded by Retrophin Incorporated. Qualifying participants must be over the age of 19 years old, not on dialysis or have received a previous transplant, and have had a renal biopsy confirming diagnosis. Participants will be compensated. For more information, please contact Laura Latta via phone number 205-975-8638 or email at Alatta@uabmc.edu.
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You may qualify to participate in an observational research study, funded by the National Institute of Health. Qualifying participants must be over the age of 18 years old, not on dialysis or have received a previous transplant, and have had a renal biopsy in the last 5 years confirming diagnosis. Participants will be compensated. For more information, please visit https://curegn.org/ or contact Courtany Grammer via email at courtanygrammer@uabmc.edu.
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If you have been diagnosed with Fabry DIsease and wish to participate in or receive information about the 6 ongoing Fabry disease studies, please contact research nurse coordinator Chrissy Singleton, RN at 975-2935
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Women are needed for a study examining how naturally occurring bacteria in the gut may impact weight loss. Participation involves eating study-provided meals for 4 weeks, completing questionnaires, providing basic body measurements, and providing stool and occasional blood samples. Meals are provided at no cost and additional compensation is available. Eligible participants must be generally healthy African American or Caucasian women, age 30-50, currently overweight, and not currently pregnant or nursing. For more information contact the FEED ME Study at 205-934-1715.
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You may qualify to participate in a 4-month research study, funded by the National Institute of Health (NIH), on blood vessel health in patients with chronic kidney disease. Qualifying participants must: Be between the ages of 19 and 65 Not on Dialysis Have moderate stage of kidney disease with 26%-60% function. Participants will be compensated. For more information, please contact UAB Division of Nephrology at 205-934-7295. Or email Salam Madi salammadi@uabmc.edu
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Researchers at the University of Alabama at Birmingham are conducting a study to investigate how daily consumption of types of foods influences body weight and composition, and other outcomes related to the risk of certain diseases. If you are between the ages of 18-50 you may be eligible to participate. Participation involves attending 5 study visits, consuming a food item daily for 30 days, and acquiring measures related to body weight, body composition, and glucose metabolism. You will be compensated for completing the study. For more information please call (205)-975-4113
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Postmenopausal women 55 years of age or older with vaginal atrophy needed. Participants must be willing to use vaginal estrogen cream for 8 weeks. If you are eligible, your participation will involve 2 visits to our clinic over an 8 week period. A physical examination will take place at the first visit and then again after 8 weeks. Participants will receive compensation up to $150 for completing the study as requested. For more information please call 205-996-7372. Or you can email us at kpnorris@uabmc.edu
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We are seeking volunteers with Type 2 Diabetes for a weight loss research study looking at the role of dietary protein in weight loss and the remission of type 2 diabetes. The study will last approximately 12 months. Participants will participate in a 16 week State of Slim group weight loss program and a 36 week State of Slim Next Steps weight loss maintenance program, with body composition scans and lab work at no charge. Participants will receive monetary stipends of $300 to reimburse for time and travel to study classes and study visits. You may qualify for this weight loss research study if you are nonvegetarian, 18 years of age or older, has Type 2 Diabetes diagnosed within the last 6 years, are overweight or obese with a BMI greater than or equal to 27. Must be willing to participate in weekly group weight loss classes for 16 weeks, bi-weekly weight loss maintenance classes for 36 weeks, and attend four study visits over 12 months at the Lakeshore Foundation Campus. Also is willing to regularly consume lean red meat or not consume any red meats. Please call (205)873-8241 or email cwyoder@uab.edu if you are interested.
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Sometimes people can experience the symptoms of depression even while on antidepressants. If you take medication for depression but have still experienced symptoms for at least 8 weeks, you may qualify for a research study testing the effectiveness of an add-on investigational therapy. Everyone qualified for this study will be seen by a doctor and receive all study-related medications, care and tests at no cost. Reimbursement for travel may be available. To learn more about this study please contact (205)-934-2484 or Sam Irvin (205)-975-6426
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