Clinical Trials

BrainREAD is recruiting autistic and typically-developing children, ages 7-13, with reading comprehension difficulties to participate in an MRI study that includes a free reading intervention through Lindamood-Bell Learning Processes. We are also recruiting typically developing children with no reading difficulties to participate. Participation involves a pre and post session which are broken up into two days each. Day 1 consist of neuropsychological evaluations and Day 2 is the MRI scan. Participants can be compensated up to $250 for both testing sessions. If interested, please call 205-202-0616, email cas-cbalab@uab.edu. or visit https://sites.uab.edu/cbra/ to fill out our contact form.
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February 12, 2024

WE NEED YOU!

We may have the right sexual health research study for YOU. Participants will be compensated.

Call us TODAY at 205-934-8166.
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Our research team is currently conducting an exercise training study in children and adolescents with cerebral palsy who can walk.
  • You must be 11 - 21 years old.
  • You will be asked to walk, jump, step, and do exercises.
  • Eligible participants will have multiple visits and can be compensated up to $430 depending on your tests.

To learn more about the study, please call (205) 774-8448 or email phuong@uab.edu.
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Are you between the ages of 11-19 with no history of mental health disorders?
Are you physically healthy?
If so, you may be eligible to participate in a study.
Compensation provided.
For more information, please call Brennan Wink at 205-975-4208 or send an
email to Brennanwink@uabmc.edu.

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The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a 75-week research study to evaluate the effectiveness of an investigational drug to treat type 2 diabetes. In this trial you will receive one of two possible once-weekly injectable medications: either semaglutide/cagrlintide (CagriSema) or tirzepatide (Mounjaro) along with diet and exercise counseling. To qualify, you must be 18 years old or older and have Type 2 Diabetes. Qualified participants will receive study drug, diabetes counseling, EKGs, eye exams, and physical exams. There is no charge for participation. Compensation for time and travel may also be available. For more information, and to see if you might be eligible to join, please contact (205)996-4015 or ccnrn@uab.edu.
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Are you experiencing pain due to endometriosis? Please consider joining a research study looking at a potential new medication to help women experiencing moderate to severe endometriosis-related pain. Study medication provided at no cost. Participants receive compensation for each visit completed. For more information please call 205-934-1322 or email slangan@uabmc.edu.
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About 12% of people in the United States are currently living with herpes simplex virus type 2 (HSV-2) genital herpes. Moderna is sponsoring the Vantage Trial, a clinical trial looking at the safety and immune response of an investigational vaccine to potentially treat HSV-2. Your participation may help advance research of an investigational treatment option for HSV-2—one that aims to treat genital herpes and relieve the burden of daily medication.

If you are living with HSV-2, you may be eligible to join. To learn more, contact the UAB Sexual Health Research Clinic at 205-934-8166.
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Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at, genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
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You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.
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We are looking for people with knee osteoarthritis to participate in a study to examine whether a diet intervention can reduce pain and improve quality of life. The commitment to this study will last approximately 7 weeks and include the following:

  • Five (5) visits to UAB where you will fill out questionnaires, complete a DEXA scan, blood draw or Quantitative Sensory testing. These visits will last anywhere from 1-3 hrs.
  • Six (6) weeks on a randomized diet where we will provide three (3) meals and two to three (2-3) snacks per day.

Participants must:

  • Be currently suffering from pain related to knee osteoarthritis
  • Be free from other serious health conditions (diabetes, cardiovascular disease, eating disorders, metabolic disease)

Participants will receive up to $250 for completing the study and meals will be provided. Please contact DIRECT at DIRECTPAIN1@gmail.com (205) 834-3628. Leave a short message with your name and number.

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If you experience urine leakage with sneezing, coughing, laughing, walking, and exercising, you may have a common condition called Stress Urinary Incontinence: “SUI” for short.

The Pippa Fitness Pessary study investigates the safety and effectiveness of a self-managed, non-surgical, non-prescription product intended to prevent urine leakage.

This study is only one month long. Participants will be compensated $250 for completing the study visits.

To learn more about the study, please contact us at (205) 934-5498 or email us at urogynecology@uabmc.edu or visit: getapessary.com.

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DAY or NIGHT, when is the best time to take your blood pressure medication?

Help us find out by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.
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Healthy participants needed if you are:
  • 18-75 years old
  • No diagnosis of any neurological disorders or psychiatric problems
  • No history of problematic drug/alcohol use in the last 3 months
For more information and to determine eligibility, please call the Neuroscience Laboratory of Social Behavior at (205) 934-8203 or email nlsb.uab@gmail.com.
**Compensation is provided**
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Major Depressive Disorder is a mental health condition characterized by periods of low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. The purpose of this clinical research study is to evaluate the safety and effectiveness of an investigational drug for Major Depressive Disorder, also known as Major Depression. Study participation may include several clinic visits over a period of up to 5 months with an opportunity to conduct some visits either virtually or in-clinic. Qualified participants will receive compensation for their time.

For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.
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If you are 14 to 39 years of age, less than 18 weeks pregnant, and planning to deliver at UAB, you may be eligible for our education-based study. This study focuses on learning about healthy behaviors and how to make positive changes that could lead to a healthier pregnancy for you and your baby. Four study visits are spread out over 13 weeks during pregnancy, and one brief post-delivery visit where study staff visit participants in the post-partum unit. Participation includes a one-on-one education session, answering several questionnaires, and collecting lab work, including blood, mouth swabs & self-collected urine samples, and vaginal swabs. Also, three times during the study, participants are given a packet to collect two swabs at home and mail them in. Participants are compensated $230 for completing all study visits and specimens. For more information, please call Leslie Black at 205-919-5945, email PrPrepStudy@uabmc.edu, or text 256-934-4991.
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UAB is looking for participants for a study investigating the effects of a new study medication on symptoms of fibromyalgia. We are looking for women aged 25-65 who are diagnosed with fibromyalgia OR are experiencing chronic widespread bodily pain. Participants will come to UAB for 7 study visits over a 3-month period. Participants will be compensated for completing all study visits.

Please call 205-996-1198 if interested.
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The purpose of this study is to evaluate if COPD is caused by exposure to heavy metals. This study will include a medical history review, a brief physical examination, spirometry, exhaled breath condensate, urine sample, blood collection, and a bronchoscopy/bronchoalveolar lavage procedure. Those who qualify will receive compensation for their time. Participation is voluntary. Participants in the study must: be 18 to 65 years of age; live in defined zip codes, 35207, 35217, 35214; and fulfill other eligibility criteria to include a medical and medication history for evaluation. For more information, please call (205) 996-1769 or email uabsuperfund@uabmc.edu.
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The purpose of this research study is to analyze cells and fluid obtained from the lungs and determine mechanism(s) by which these cells are impaired in their ability to reduce the severity of lung infections. This study will include a medical history review, a brief physical examination, spirometry, and a bronchoscopy/bronchoalveolar lavage procedure. Those who qualify will receive compensation for their time. Participation is voluntary. Participants in the study must: be 18 to 65 years of age; live in defined zip codes, 35207, 35217, 35214; and fulfill other eligibility criteria to include a medical and medication history for evaluation. For more information, please call (205) 996-1769 or email uabsuperfund@uabmc.edu.
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We are asking you to take part in this research study because you are a resident of North Birmingham or Tarrant and may have exposure to arsenic due to industrial activity in the area. This research study is now enrolling adults within the zip codes, 35207 and 35217. After confirming enrollment eligibility, those who qualify will be randomized to receive either folic acid supplementation or a placebo at no cost. We will collect a brief medical and medication history, collect samples of urine and blood, perform spirometry testing, and complete a respiratory questionnaire.

Participation is voluntary, and you will be compensated for your time. Participants in the study must: be 18 to 65 years of age; a resident of 35207 or 35217 zip codes; not currently pregnant or currently taking folic acid; and fulfill other eligibility criteria. For more information, please call (205) 996-1769 or email uabsuperfund@uabmc.edu.
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If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
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People with dementia sometimes do not cooperate with care. They may refuse to bathe, change clothes, or refuse to take medications. The purpose of this study is to test if a caregiver coaching program can help family caregivers better manage refusal behaviors by increasing their use of problem-solving strategies and decreasing any negative coping strategies. To participate, you must be at least 18 years old, live in Alabama, and live with and provide unpaid care to a family member with dementia who refuses help or care. You will receive 9 1-hour coaching sessions over Zoom at a time that works for you. You will be asked to complete surveys and questionnaires, and you will be paid for doing these things. All surveys and questionnaires are completed online. There is NO travel to UAB. Please email CURBIT@UAB.EDU for more information.
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DAY or NIGHT, when is the best time to take your blood pressure medication?

Help us find out by joining our study at UAB by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

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Then you may be eligible to participate in a study to see if providing healthy, home-delivered meals improves your health and helps you lose weight after having a baby. To be eligible you must be at least 18 years of age, no more than 18 weeks (or about 4 months) post-delivery, Medicaid or WIC eligible, and have received your prenatal care at a UAB clinic. For this study, you will be asked to come to UAB for 2 study visits. If you participate, you will receive 10 study-provided meals per week for a total of 8 weeks. You will be compensated for your time. If you have any questions or to confirm eligibility, please contact Camille Worthington at (205) 975-8873 or Email: cschneid@uab.edu.
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UAB researchers are looking for adults (ages 25-65) who are suffering from demoralization - feelings of hopelessness or meaninglessness - to participate in a research study evaluating a novel medication.

To see if you qualify call 205-379-7527.
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If the answer to all of these questions is YES, you could be eligible to participate in a research study examining the impact of gender identity, hormone levels and sex assigned at birth to pain sensitivity in people who have chronic low back pain. – the ERASED study (Racial and Socioeconomic Differences in Chronic Low Back Pain).

The commitment to this study is two visits that will last approximately 4-5 hours and include:

  • One (1) telephone screen
  • Two (2) visits to UAB where you will fill out questionnaires, have a single blood draw, take part in pain sensitivity and functional testing.

If you are eligible to participate in this study, you will receive up to $400.

Participants must:
  • Identify as transgender
  • Be between 18 and 85 years of age
  • Have none of the following health conditions (HIV+, cardiovascular disease, uncontrolled hypertension)

Participants can be on HRT (hormone replacement therapy) or not.

To find out more about this study, call 205-934-8743. For information regarding research studies and rights of participants, call 205-834-3625.

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CURB-2 is an abbreviation we use to refer to this study because there was a similar study completed and published in 2016 called CURB, which stands for Cocaine Use Reduction with Buprenorphine. The results from that study showed that using injectable naltrexone and sublingual buprenorphine was beneficial to participants on high doses of the medication. This study will give injectable naltrexone and injectable buprenorphine to make sure medication doses are consistent to confirm potential benefits.

There are no approved treatments specifically for cocaine use disorder. We are looking for adults (18-65 years of age) who are using cocaine and who are interested in reducing or stopping their use. The purpose of our study is to test a combination of two medications for 2 months as a possible treatment for cocaine use disorder.

This study includes the use of a placebo, which looks like the medication we are testing but does not include any active medicine. Study medication and assessments will be provided to participants at no cost. Participants will receive compensation for their time and efforts.

Study information will be kept strictly confidential. Your privacy is important to us.

Call us for more information at 205-996-0211 or email us at curb2study@uabmc.edu
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If so, they could be a part of a study that looks at the long-term effects of receiving the COVID-19 vaccine. Healthy children or children with conditions affecting their immune systems are eligible to enroll. Blood samples and nasal swabs will be collected every 2 months for one year. An echocardiogram and EKG will also be required at the second visit. Compensation for participation is available. To learn more, contact the UAB study team: 205-638-2629 or mlpurser@uabmc.edu
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You or your child must be a male or female aged 6 to 17 years of age with an underlying medical condition, positive for COVID-19, and experiencing symptoms. If you qualify for the study, you will be provided the medication to take for 5 days. The entire study will last approximately 1 month, with several clinic and in home visits. Blood samples will be collected throughout the study period. Compensation for participation is available. To learn more, visit covidpillstudy.com or contact the UAB study team: 205-638-2629 or mlpurser@uabmc.edu
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The participant may be healthy or have a chronic condition that puts them at risk for severe disease. Blood samples will be required over the six month study period. Compensation for participation is available. To learn more, contact the UAB study team: 205-638-2629 or mlpurser@uabmc.edu
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Congenital CMV infection is the most common infection passed from the mother to baby during pregnancy. It is also the most common non-hereditary cause of hearing loss and brain damage in children. You or your child will have 3 injections, several months apart. You will have approximately 11 clinic visits over the 18 month study period. Saliva swabs, urine, and blood samples will be required. Compensation for participation is available. To learn more, visit CMVibeTrial.com or contact the UAB study team: 205-638-2629 or mlpurser@uabmc.edu
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Help us find out by joining our study at UAB by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

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Are you tired of constantly fearing urinary leakage? Say goodbye to embarrassing accidents and take control of your life! We believe in living life to the fullest without worrying about Urgency Urinary Leakage. Compensation is provided.

Call us today at (205) 934-5498 to join our urogynecology clinical trial and find the perfect treatment plan tailored to you.
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The UAB Department of Psychiatry is recruiting healthy adolescent participants for a clinical research study. The study will compare healthy adolescents and adolescents with functional seizures (FS).

To participate in this research, you must:
- be 11 to 18 years old
- have no diagnosed medical conditions
- have a parent/guardian available to participate in lab visits

If you choose to participate in the study, you will be part of the healthy control group. You will come for 2 lab visits 13 weeks apart. The adolescent can be compensated up to $100 total. To find out more about the study, call 205-975-4205 or email pedshealthlab@uabmc.edu.
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You may be eligible to participate if you identify as female, White or African American, are aged 35-65, and have a BMI of 30+. Participants will receive $50 as thanks for their participation.

This study is a 5-hour workshop delivered in groups that is based on principles of acceptance and commitment therapy (ACT). Participants will learn new skills to facilitate the adoption of healthy lifestyle behaviors, such as eating a healthy diet and exercising regularly. These skills include identifying values, tolerating the discomfort associated with lifestyle change, identifying self-sabotaging thoughts, and more!

For more information, please contact Andrea at andrealdavis@uabmc.edu or 205-206-9434.
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Do you identify as an individual living with cancer and part of the LGBTQIA+ community or a care partner of someone in this community? A research lab at the University of Alabama at Birmingham is looking to learn about the day-to-day experiences of LGBTQIA+ cancer survivors and their care partners. We are interested in how individuals manage difficult situations related to their respective roles in their relationships. Individuals living with cancer often encounter stressful situations that can impact their mood and any additional stressors from living as a sexual or gender minority with a lack of resources adds an increased risk of experiencing stressful situations. The goal of this work is to develop resources that better support the well-being of LGBTQIA+ individuals living with cancer and their care partners. This study will take place FULLY online with completion of daily surveys. All participants will be compensated. To learn more about our study contact us at starlab@uab.edu
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The University of Alabama at Birmingham (UAB) is inviting Hispanic or Latino/a family caregivers to complete short surveys for our study. Your answers will help us understand your daily experiences and develop services to better support caregivers in the community. You will be paid for your time. Your answers will remain anonymous. To learn more contact us at starlab@uab.edu or call Lorelí Alvarez at 205-996-0339.
To be contacted by the research team register here: https://uab.co1.qualtrics.com/jfe/form/SV_d3TmeAlFEPBRmNU

¿Cuidas de un familiar con problemas de memoria o demencia/enfermedad de Alzheimer?
La Universidad de Alabama en Birmingham (UAB) está invitando a cuidadores familiares hispanos y latinos para que completen breves encuestas para nuestro proyecto. Tus respuestas ayudarán a comprender mejor las experiencias del día a día y a desarrollar servicios para apoyar mejor a los cuidadores familiares de la comunidad. Les compensaremos por su participación. Sus respuestas permanecerán anónimas. Para saber más escribe a starlab@uab.edu o llama por teléfono al 205-996-0339 y pregunta por Lorelí Alvarez.
Para ser contactado por el equipo de investigación haga click aquí: https://uab.co1.qualtrics.com/jfe/form/SV_d3TmeAlFEPBRmNU
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Study of an investigational device for improving glycemic control in adults with type 2 diabetes. It is an external headset that attaches behind the ears to deliver a small electrical current to the vestibular system – the balance system in the inner ear. Previous research suggests that activating the vestibular nerve may cause a reduction in body fat but also improve glycemic control. The aim of the study is to evaluate whether frequent use of the device, along with a lifestyle modification program, can improve glycemic control. Contact 205-996-4015 or 205-996-4020 for more information.
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You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.
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If you are 19 or older and an exclusive vaper (meaning only vaping and no cigarette smoking) who lives with someone who does not vape, or a non-vaper who lives with an exclusive vaper, you may qualify for this study. The person who vapes/does not vape can be your roommate, partner, etc. Potential participants will be screened before enrollment to ensure they are eligible. Once enrolled, participants will blow into a spirometer to measure their lung function and answer questions on respiratory symptoms. If you are interested, please email at rvlab1665@gmail.com or provide your details via this link: https://uab.co1.qualtrics.com/jfe/form/SV_6ExuSQMcdg3AC8K, and we will contact you. Thank you!
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Then you may be eligible to participate in a study to see if providing healthy, home-delivered meals improves the health of pregnant moms and their baby. To be eligible you must be at least 18 years of age, no more than 20 weeks gestation, receiving prenatal care at a UAB clinic, and planning to deliver at UAB. For this study, you will be asked to come to UAB for 1 study visit and to complete 1 study visit by phone. If you participate, you will receive 10 study-provided meals per week. You will be compensated for your time. If you have any questions or to confirm eligibility, please contact Camille Worthington at (205) 975-7274 or email cschneid@uab.edu.
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We are looking for transgender men and non-binary people who are at least 18 years old interested in starting testosterone therapy to participate in a sexual health research study. Call the UAB Sexual Health Research Clinic at 205-934-8166. Compensation provided.
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Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
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We are actively recruiting for research studies focused on women with one of the following conditions:

1. Accidental bowel leakage (fecal incontinence)
2. Urinary leakage (urinary incontinence)

Please call 205-934-5498 to learn more about these studies.
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If you are currently pregnant, 18 or older, planning to deliver at UAB, and planning to breast feed, you may be eligible for our study!

This study focuses on better understanding breast milk composition, the presence or absence of CMV in breast milk, and its possible transmission to babies. CMV is a common virus that most people in the US are infected with by adulthood. Participants will meet with study staff once a month for six months to collect non-invasive samples and answer a questionnaire. Samples collected include oral swabs from you and your baby, a small quantity of breast milk and a skin swab from you, as well as a urine and stool sample from your baby. Participants will be compensated up to $300 for completing the study visits and providing samples. Eligible participants may also qualify for additional sub-studies for additional compensation up to $800.

For more information, please contact us via phone or email at:
Phone: 205-975-3752
Email: milk@uabmc.edu
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BrainREAD is recruiting children with autism and typically-developing children, ages 7-13, who have reading comprehension difficulties to participate in an MRI study that includes a free reading intervention through Lindamood-Bell Learning Processes. Participation involves two sessions each of which are broken up into two days - one day of neuropsych assessments and one day for the scan. Participants can be compensated up to $125 for the first scan and tests with an additional $125 for the follow-up scan and tests, 12 weeks later. If interested, please call 205-202-0616, email cbralab@ua.edu or visit cbra.ua.edu/brainread.html and fill out our contact form.
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If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
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Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.
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The STARS Lab lead by Dr. Caroline G. Richter is currently recruiting for the study: Socio-emotional competencies in children and adolescents with learning differences
This study seeks to examine socio-emotional constructs, such as motivation, resilience, and stigma using an assessment survey. The project’s final goal is to provide educators and parents with targeted socio-emotional intervention techniques for a more holistic perspective on student learning.
All English-speaking children from 11 to 14 years of age are eligible. Students with Specific Learning Disabilities are encouraged to participate.
Click here to learn more: https://drive.google.com/file/d/1JCw1f7PfRTRHJhdlV39ZHH_g3nThBwBq/view?usp=sharing
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The UAB TRIP Lab is studying the effects of concussion on driving among adolescents and young adults, from acute post-injury to symptom resolution. We are in search of 16-24 year olds who have had a concussion within the last 10 days AND who have NOT had a concussion (control group) to participate in a longitudinal study. Participants will visit UAB once per week, where they will drive in a fully immersive, state-of-the-art driving simulator and complete some cognitive and/or balance tasks. Participant will also complete surveys throughout the week. Participants are compensated up to $610 for their time. If interested, please contact the UAB TRIP Lab, (205) 975-9440 | TRIPLAB@UAB.EDU
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This research study will look at a certain part of the immune system, called the complement system, as it relates to a hormone called estradiol. We will compare the components of your tears and blood to see how the complement system is affected by estradiol in women across different ages. We will also use some cells gently collected from the front of your eye to see how proteins of the complement system are made. We will use your tears, blood, and cells for testing if you agree to donate them to the study. The study will enroll 48 women between the ages of 35 and 64. Eligible participants will receive compensation for their time. To find out more about the study, kindly email us at: SOeyes@uab.edu
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Are you a HIV negative, generally healthy adult between the ages of 18-55?
The Alabama Vaccine Research Clinic at UAB are seeking volunteers for a phase 1 HIV prevention study. This study is to evaluate the safety and immunogenicity of synthetic DNAs encoding in adults without HIV. This trial is in search of healthy HIV negative adults between the ages of 18-55. Procedures will include blood draws and injections of study vaccine, as well as the collection of white blood cells. White blood cells will be collected by a procedure called leukapheresis. Participants will be compensated for their efforts in this study.

If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
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You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.
Published in Clinical Trials
March 28, 2023

Trans Men

We are looking for transgender men and non-binary people who are at least 18 years old interested in starting testosterone therapy to participate in a sexual health research study. Compensation up to $465 Please call the UAB Sexual Health Research Clinic at 205-934-8166
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The Functional Outcomes from Diet in Multiple Sclerosis (FOOD for MS) study will test whether eating healthy foods and losing weight can improve physical function, pain, fatigue, mood, and sleep in adults with relapsing-remitting or secondary progressing MS. We will also explore the how diet impacts inflammation, immunity, and metabolic biomarkers that may contribute to MS symptoms and progression. Eligible participants must be 18-65 years old, diagnosed with Relapsing Remitting Multiple Sclerosis or Secondary Progressive Multiple Sclerosis, and be able to travel to one of our two study sites, Birmingham, Alabama or St. Louis, Missouri three times points over 8 months. Participants will be compensated $150 for completing all study visits and have their groceries provided for the length of the study. Please contact Kathryn Green at kathryngreen@uabmc.edu or by phone 205-319-1424 or Meghan Taylor at meghan13@uab.edu for more information and to see if you qualify.
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Do you have a history of kidney stones?
If you are 18 or older with a history of calcium oxalate kidney stones, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
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f you are 18 or older and in good health, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
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Healthy adults needed for a study on vitamin C
If you are 18 or older and in good health, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
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Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at, genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
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We are conducting a research project to examine effects of a coach-guided videoconferencing acceptance and commitment therapy (ACT) program on improving psychological health (e.g., depressive symptoms) in persons with a spinal cord injury sustained within 5 years. You may qualify for the study if you are adults (age 18 or over) who had a traumatic or non-traumatic spinal cord injury within 5 years and have a web-enabled device (a computer/laptop, a smartphone, or a tablet PC) with the internet access at home. This study will involve completion of questionnaires three times and 8 weekly videoconferencing sessions by the ACT coach if you are assigned to the ACT group. Participants will be compensation at study completion (up to $215 as the ACT group). For questions and more information, contact Jessica Hawkins at jshawkins@uabmc.edu or 205-975-2882.
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The benefits of taking statins for older adults without heart disease are not fully understood. About 20,000 older adults along with a team of researchers and clinicians across the country will be involved in the PREVENTABLE study. The purpose is to learn if taking a statin is helpful for older adults. Are you a good fit for PREVENTABLE? Contact the study team to find out.

See the website at www. preventabletrial.org

Please call or text: (205) 224-2567 or email destinytaylor@uabmc.edu if you are interested.
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Our research team is currently conducting a clinical research study in men and women 18 – 50 years old to evaluate a vaccine in preventing gonorrhea infection. Eligible participants will have a 50/50 chance of receiving either two doses of meningococcal vaccine or placebo. Participants will have multiple visits over 16 months and receive compensation for their time.
Phone number A- 205-934-8166 - Sexual Health Research Clinic.
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Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
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We are looking for people who identify as trans or cisgender, are 18-65 years of age and would like to take part in a research study examining the impact of gender identity, hormone levels and sex assigned at birth to pain sensitivity and immune cell activity. The commitment to this study will last approximately 3 hours where you will fill out questionnaires, have a single blood draw and take part in pain sensitivity testing. Participants must: Be free from certain health conditions (HIX+, cardiovascular disease, uncontrolled hypertension). Participants can be on HRT (hormone replacement therapy) or not. Participants will receive up to $100. To find out more about this study, call 205-834-3625 or email shinestudyuab@gmail.com.
Published in Clinical Trials
March 01, 2023

DECLARE Study

We are recruiting healthy men & women who are between 55-75 years of age AND have hypertension for the DECLARE Study.

The purpose of this research study is to examine the effects of 10 weeks of exercise on the brain. DEcreasing Cognitive Loss and Vascular Rarefaction with Exercise (DECLARE) is focused on the elucidation of exercise effects on brain health and the way by which exercise mitigates age-related growth factor deficiencies, hypertension and cognitive decline.

To participate in this research, you must:
– have high blood pressure
– be between 55-75 years of age
– be healthy (Ok to be on medication)
– not currently exercising

Please contact us at 205-996-5592 or use the following link to complete the 5 minute screening questionnaire: https://uab.co1.qualtrics.com/jfe/form/SV_6FigP3lOJYdvl9c
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Are you between the ages of 11 and 19?

Are you feeling sad, down, or hopeless?

Are you feeling guilty, tense, or irritable?

If so, you may be eligible to participate in a study.

Compensation provided.

For more information, please call Brennan Wink at 205-975-4208 or send an email to Brennanwink@uabmc.edu.

Published in Clinical Trials
February 22, 2023

Lung Health Cohort

One Breath Matters.

Are you or someone you care about age 25-35 and interested in lung health? Join the landmark Lung Health Cohort Research Study to improve the health of future generations.

The pioneering NIH-funded study will follow 4,000 young, healthy adults to paint a clearer picture of lung health and the factors involved in predicting and preventing lung disease.

To learn more, visit: Lung.org/lung-study 
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We are conducting a research project to evaluate if coach-guided videoconferencing acceptance and commitment therapy (ACT) is effective for improving psychological health in family caregivers of people with dementia. You may qualify for the study if you are adults (age 18 or over) who are currently taking the primary responsibility for the care of a relative with dementia living in the community (i.e., your relative is not living in a nursing home) and have a web-enabled device (a computer/laptop, a smartphone, or a tablet PC) with the internet access at home. This study will involve completion of questionnaires three times and 10 weekly videoconferencing sessions by the ACT coach if you are assigned to the ACT group. Participants will be compensation at study completion (up to $150 as the ACT group). For questions and more information, contact Jessica Hawkins at jshawkins@uabmc.edu or 205-975-2882.
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Did you or you know someone who had a stroke at least 6 months ago and still having difficulties in using the affected arm in your daily activities? If so, we would like o talk to you about our current study. If eligible, you will be asked to visit our clinic multiple times for training and assessment procedures. This study is being done as a distributed form of Constraint-Induced Movement Therapy (CI Therapy) protocol termed Keys Treatment that can be easily implemented in the clinic. For more information, please contact Mary Bowman, OTR/L, C/NDT, LSVT-BIG (mbowman@uab.edu or 205-934-0069) or Sarah dos Anjos, OTD, PhD (smanjos@uab.edu).
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We are conducting a research study to investigate how light-sensitive cells in the retina regulate eye growth and refractive errors like myopia (nearsightedness).


This study has been approved by the University of Alabama at Birmingham Institutional Review Board (ref: 300008644).


You will be eligible to participate in the study if you are:

-18-35 years old.

-You have corrected to normal vision (with glasses and contact lenses)

-You have good general and ocular health

This study includes a single visit that is expected to last 90 minutes or less. If eligible, you will be compensated $50.00 for your time and participation in the study.


Dr. Safal Khanal

Principal Investigator

Department of Optometry and Vision Science

University of Alabama at Birmingham


If you need more information or would like to participate in the study, please contact:

Dr. Safal Khanal

skhanal@uab.edu

(205) 934 4558
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You may be eligible to participate in a research study: If you are a healthy female, between age of 18-50, still having a regular menstrual cycle & you are NOT on hormonal birth control (birth control pills or shots (i.e. Depo shot) or IUD, like Mirena). And, if you are willing to undergo an endometrial biopsy procedure. Participants will be compensated total of $200. Only requires 2 visits. For information, call us at 205-934-5498 or email Stephanie Clevenger at slangan@uabmc.edu.
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Your baby will have 2 injections, which will be 8 weeks apart. You will be asked to return to the study site with your baby up to 7 times over the course of 15 months. Your baby will be closely monitored by the study team if any symptoms of COVID-19 are reported at any time throughout their participation. Nasal swabs and blood draws will be required at 3-4 of the study site visits. Compensation for participation is available. To learn more, visit BabyCOVEStudy.com or contact the UAB study team: 205-638-2629 or mlpurser@uabmc.edu
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The University of Alabama at Birmingham (UAB), in collaboration with Novo Nordisk, is conducting a 3-year research study to see if CagriSema, an investigational weekly medicine being studied for the treatment of obesity is also safe for the heart and blood vessels.

We are doing this study to see if CagriSema (Cagrilintide/semaglutide), a new medicine intended for the treatment of obesity, is safe for use in people living with obesity and cardiovascular disease. The study will also include some people with type 2 diabetes and/or chronic kidney disease.

You may qualify to participate if::
  • You have had a stroke, a heart attack (myocardial infarction), or have poor circulation (peripheral
  • arterial disease)
  • You are 55 years of age or older
  • You are living with obesity (BMI ≥ 30 kg/m2 )
  • You can have type 2 diabetes and/or chronic kidney disease
  • You are able to attend regular clinic visits and receive phone calls over
  • a period of 3 years

Want to know more about the REDEFINE 3 study?
Call the study team at (205) 996-4015 or via email ccnrn@uab.edu
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If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
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Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.
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The RECOVER study was designed in partnership with many of the nation’s top experts in treatment-resistant depression, and approved by Medicare, to provide additional evidence of the benefit of VNS Therapy. If the results confirm previous studies, Medicare and other insurers may start to cover it.

People who participate in RECOVER will receive VNS Therapy and all study-related care at no cost to them.

To join the RECOVER study, you must be 18 years or
older and:

1. Currently depressed
2. Have depression, or bipolar depression, that has lasted for at least two years or recurred several times
3. Have tried at least four types of antidepressant treatments and not found them helpful
4. Have Medicare Insurance
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We are currently seeking Gulf War Veterans to participate in a brain imaging research study. Healthy Gulf War Veterans and Veterans with chronic health problems are invited to participate. Participation involves 1-2 visits to UAB for 2.5 hours total. Participants undergo MRI brain scan, blood draw, and complete several questionnaires. Participants who complete the study receive $150 compensation. Please email chloej@uab.edu or call 205-434-1502 for more information and to find out if you're eligible.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy African American men having no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested

Published in Clinical Trials

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.

Published in Clinical Trials
Are you 19 years or older? Are you being treated with lifestyle changes or treated with one or more oral diabetes medications ?

The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 78 week research study to look into how well semaglutide once weekly medicine works in participants with obesity and type 2 diabetes

Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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Clinical Study for Patients with Dry Eye Associated with Sjögren’s Disease. If you are an adult with Dry Eye Disease associated with Sjögren’s, you may be eligible to take part in a clinical research study being conducted by Sylentis S.A.U. The purpose is to compare the study eye drop to placebo (eyedrop without medication) in treating the signs and symptoms of Dry Eye associated with Sjögren’s.

You may be eligible to take part in the SYL1001_V Study if:
• You are 18 years or older
• You have a diagnosis of Sjögren’s
• Other entry criteria apply and your eligibility will be determined by
the study staff


If you decide to take part in the study, your participation could last approximately 3.5 months and consist of 5 to 6 visits to the study center. You will be reimbursed for each completed visit.
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Are you a caregiver? Do you know someone that is a caregiver? Would you like to earn $20? If so, the Caring for Adults with Difficulties Study (CFAD) needs you! This study examines stressors of caregivers to aging adults, their social support networks, caregiving demands, and personal experiences. To be eligible, you must care for a family member or friend at least 5 hours per week. You must also complete a 45 minute survey online or over the phone. Please contact us by phone (205-975-9452) or email (mjfields@uab.edu). We look forward to your participation asa we are still recruiting participants!
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The Alabama Vaccine Research Clinic at UAB are seeking volunteers for a phase 1 HIV prevention study. This study tests the body’s immune system response to, a protein similar to what is found in HIV. The immune response prepares the body to recognize the same protein in HIV and fight the virus if a person is exposed to HIV in the future. Participants will be compensated over $750 for their efforts.

If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
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Receive compensation and Free 20-Week Exercise Program.

Eligible enrolled participants will receive:
- Supervised exercise training at no cost
- Blood pressure medication at no cost
- Convenient parking at no cost
- Compensation for time

If you are interested, please call 205-996-3005 and mention The ACES Study or apply here -https://www.uab.edu/medicine/exercise/volunteer-clinical-trials/aces-trial.
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The University of Alabama at Birmingham, Department of Family and Community Medicine, is conducting a 12-month research study to test the effectiveness of a diabetes management intervention. If you have type 2 diabetes, are 18 years or older, and self-identify as Black or African American, you may be eligible to participate. Participants will be compensated up to $300 for completing the study.

For more information, please contact us at: 205-224-2567, or freedom@uabmc.edu, or fill out this pre-screening form and we will get in touch with you: https://redcap.link/freedom
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We are looking for individuals to participate in a study that looks at the relationship between endorphins in plasma and human immunodeficiency virus (HIV) associated chronic pain. To participate in this study we are looking for people with or without HIV between the ages of 19 and 64 years old, free from serious medical conditions, and able to come to two testing sessions one week apart. Participants will receive up to $200 for completing the study. You may not be eligible to participate if you have significant health problems, are pregnant, or are taking certain medications. Please email, jxjuncos@uabmc.edu, or call 205-934-6609. Leave a short message with your name, number and mention that you are interested in the Chronic Widespread Pain in HIV study.
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Help us find out by joining our study at UAB. You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must have a BMI: 30-45 kg/m2), have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
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The purpose of this research study is to better understand the long-term effects of COVID-19, and who is at greatest risk of having long-term effects. We will do this by studying people with, and without, a history of COVID-19 over several years. This is part of a nation-wide research initiative called RECOVER. If you are interested contact COVID-19research@uabmc.edu

This study will last up to four years and will involve doing in-person visits every 6 months and filling out an online questionnaire from home every 3 months. At the first study visit you will be asked a series of questions or fill out a questionnaire about who you are (such as age, sex, or race), medical conditions that may affect the chances of having long-term effects of COVID-19, whether you have been vaccinated against COVID-19, and any symptoms you currently have. You will have a brief medical exam and we will also collect samples of your blood, saliva, stool, nasal swab and urine. Some participants will be invited for additional medical examinations and tests. You will be compensated.
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The Targeted Exercise for African Americans with Multiple Sclerosis (TEAAMS) study will examine whether a 16-week home-based, racially-tailored exercise training program can provide improvements in walking dysfunction, symptoms, and quality of life among Black/African Americans with MS who live in rural communities in the Southeastern US. Eligible participants must be 18-64 years old, diagnosed with MS, self-identify as Black or African American, and live in the Southeastern US. Participants will be compensated $90 for completing all study visits. Please contact Edson Flores at enrl@uic.edu or (833) 727-1887 for more information and to see if you qualify.
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Adult ages 40-80 are needed for a study about the anti-inflammatory effects of ensifentrine in patients with COPD. The study involves 7 visits in our clinical research unit, and the collection of urine and blood. Compensation up to $700. For more information, call 205-996-2727 or email Carrie at LungHealth@uabmc.edu.
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Help us find out by joining our study. The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting an exciting research study, in collaboration with Pennington Biomedical Research Center, to investigate whether intermittent fasting or calorie restriction (i.e., losing weight) can improve health and slow the aging process.

If you are randomly selected to do calorie restriction, you may lose weight by eating less. If you are randomly selected to do intermittent fasting, you will fast for 16 hours per day and eat dinner by 6 pm about 6 days per week (1 break day per week). We want you to be successful: the study provides intensive coaching and support to help you successfully lose weight or practice intermittent fasting.

To qualify, you should:

Be 25-45 years old
Have a BMI between 22-30 Calculate your BMI here
Be healthy
Not currently taking any medications or supplements for chronic conditions
Not smoke, vape, or use tobacco products currently or within the last 6 months
Not currently participate in a regular program of heavy physical activity (e.g., jogging, running, or riding fast on a bicycle for 30 minutes or more per day)
The study involves collecting a medical history, body fat and bone scans, blood draws, urine collection, questionnaires, and other simple tests. Participation in the study will last approximately 7 months. Compensation of up to $1,500 is offered for the completion of this study. If you are interested in participating and think you may be eligible, please click the button below to screen online, call 205-934-1457, or email dial@uab.edu.

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You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.
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Adult Volunteers ages 18-75 are needed for a study examining the relationship between oxalate handling in the blood and urine in persons with and without chronic kidney disease. The study involves consuming prepared meals over 5 days twice, one-day long visit in our clinical research unit, and the collection of urine and blood. Compensation up to $360. For more information, call 205-224-7324 or email kidneystoneresearch@uabmc.edu.
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Healthy individuals ages 18-75 are needed for a study examining the relationship between oxalate handling in the blood and urine in persons with and without chronic kidney disease. The study involves consuming prepared meals over 5 days twice, one-day long visit in our clinical research unit, and the collection of urine and blood. Compensation up to $360. For more information, call 205-224-7324 or email kidneystoneresearch@uabmc.edu.
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Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.
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If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
Published in Clinical Trials
Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
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The Kids Low Vision and Reading (KLoVR) study aims to better understand reading ability among children with permanent vision impairment. We need to recruit children ages 6 to 16 with normal vision (glasses are ok) for a comparison group. Testing includes vision testing, reading tests and memory tests and lasts 2 to 2.5 hours. No eyedrops are used. Participants are compensated with a $100 gift card and free parking in the Callahan Eye Hospital parking deck. Please call the Clinical Research Coordinator, Caroline Durena, in the Center for Low Vision and Rehabilitation at (205)488-0788 for more infor‐ mation about the study and to see if you qualify. This study is funded by the National Institute for Disability, Independent Living and Rehabilitation Research.
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If you are currently pregnant, 18 or older, planning to deliver at UAB, and planning to breast feed, you may be eligible for our study. This study focuses on better understanding CMV, a common virus most people in the US are infected with by adulthood, its transmission through breast milk from mother to baby, and how the body protects itself from the virus. Participants will meet with study staff once a month for six months to collect non-invasive samples and answer a questionnaire. Samples collected include oral swabs from you and your baby, a small quantity of breast milk and a skin swab from you, and a urine and stool sample from your baby. Participants will be compensated up to $300 for completing the study visits and providing samples. Eligible participants may also qualify for additional sub-studies for additional compensation up to $800. For more information, please contact Amanda Rafferty at 205-975-3752 or email amrafferty@uabmc.edu.
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We are looking for current pessary users to trial a new investigational pessary, which may be more comfortable and easier to use than your current pessary. Participants will be asked to: Continue to wear your current pessary for 1 month Be willing to use a study pessary for 3 months Attend 1-2 visits (at no cost to you) in addition to your pessary usual care Participants will receive: $300 ($100 gift card given for each extra visit and then at the end of the study) For more information call 205-934-5498
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