Clinical Trials
Vitamin C and Kidney stones study
If you are 18 or older with a history of calcium oxalate kidney stones, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
For more information email kidneystone@uabmc.edu
Vitamin C and Kidney stones study
If you are 18 or older and in good health, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
Ultraviolet Light induced effects on the skin immune response- Healthy Volunteers Needed
Seeking Mothers of Color
You are eligible to participate if you are a person of color and you have childbirth, prenatal, and/or postnatal experiences with a U.S. BFHI hospital.
Participation will take no longer than 90 minutes and will involve:
• a brief online survey
• a phone interview
Participants will receive a $50 online gift card upon completing the study.
To enroll or get more information, please email Jaclyn Wells at wellsj@uab.edu.
See the website at www. preventabletrial.org
Please call or text: (205) 224-2567 or email destinytaylor@uabmc.edu if you are interested.
Behavior Change Program for Promoting Physical Activity in Persons Newly Diagnosed with MS
Participants will involve in a 12-week lifestyle physical activity behavior change program remotely delivered via email and Zoom one-on-one chat sessions. Participants will also complete two assessments of physical activity and MS outcomes before and after the program. All information provided will remain confidential. The researchers are seeking participants who:
• Are 18 years of age or older.
• Diagnosis of MS within the past two years
• Able to walk without assistance
• Engaging in low levels of physical activity
• Internet and email access
• Able to read newsletter with a font size of 14 points
• Currently on an MS treatment (DMTs)
Participants will receive compensation of $50 for their time and effort.
If you are interested in participating in this research or would like to learn more about the project, please get in touch with Lexi Huynh at enrl@uabmc.edu or call (205) 975 - 1494.
Gonorrhea Prevention Vaccine Study
Phone number A- 205-934-8166 - Sexual Health Research Clinic.
• Five (5) visits to UAB where you will fill out questionnaires, complete a DEXA scan, blood draw or Quantitative Sensory testing. These visits will last anywhere from 1-3 hrs.
• 6 weeks on a randomized diet, we will provide three (3) meals and two to three (2-3) snacks per day.
Participants must:
• Be currently suffering from pain related to osteo knee arthritis
• Be free from other serious health conditions (diabetes, cardiovascular disease, eating disorders, metabolic disease)
Participants will receive up to $250 for completing the study and meals will be provided. Please contact DIRECT at DIRECTPAIN1@gmail.com (205) 834-3628. Leave a short message with your name and number.
DECLARE Study
The purpose of this research study is to examine the effects of 10 weeks of exercise on the brain. DEcreasing Cognitive Loss and Vascular Rarefaction with Exercise (DECLARE) is focused on the elucidation of exercise effects on brain health and the way by which exercise mitigates age-related growth factor deficiencies, hypertension and cognitive decline.
To participate in this research, you must:
– have high blood pressure
– be between 55-75 years of age
– be healthy (Ok to be on medication)
– not currently exercising
Please contact us at 205-996-5592 or use the following link to complete the 5 minute screening questionnaire: https://uab.co1.qualtrics.com/jfe/form/SV_6FigP3lOJYdvl9c
adolescent study for depression
Are you felling sad, down, or hopeless?
Are you feeling guilty, tense, or irritable?
If so, you may be eligible to participate in a study.
Compensation provided.
For more information, please call Brennan wink at 205-975-4208 or send an
email to Brennanwink@uabmc.edu
Lung Health Cohort
Are you or someone you care about age 25-35 and interested in lung health? Join the landmark Lung Health Cohort Research Study to improve the health of future generations.
The pioneering NIH-funded study will follow 4,000 young, healthy adults to paint a clearer picture of lung health and the factors involved in predicting and preventing lung disease.
To learn more, visit: Lung.org/lung-study
Family caregivers of people with dementia are invited to participate in the coach-guided videoconferencing acceptance and commitment therapy study
Adults 50 and Older Needed for a Weight Loss Study!
You may qualify for this weight loss research study if you:
• Are 50 years old or older
• Have obesity (BMI of 30-50 kg/m2)
Check your BMI at:http://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm
• Are willing to participate in virtual group weight loss classes, follow the State of Slim diet and exercise recommendations, and complete five study visits over a 12-month period at the Lakeshore Foundation Campus.
Please call 205-975-9868 or email healthylivinglab@uab.eduif you are interested.
Participants aged 21 to 65 are invited to participate in alcohol and pedestrian safety study.
Application of a Reimbursable Form of Constraint- Induced Movement Therapy for Upper extremity Recovery Following Stroke: A Pilot Study
The role of S-cone neural activity in eye growth regulation and refractive development
This study has been approved by the University of Alabama at Birmingham Institutional Review Board (ref: 300008644).
You will be eligible to participate in the study if you are:
-18-35 years old.
-You have corrected to normal vision (with glasses and contact lenses)
-You have good general and ocular health
This study includes a single visit that is expected to last 90 minutes or less. If eligible, you will be compensated $50.00 for your time and participation in the study.
Dr. Safal Khanal
Principal Investigator
Department of Optometry and Vision Science
University of Alabama at Birmingham
If you need more information or would like to participate in the study, please contact:
Aaron Ousterhout
ajouster@uab.edu
(205) 975-0424
Healthy Women Needed for a Research Study
BabyCOVE Study: Evaluates the COVID-19 vaccine in healthy infants aged 12 weeks to less than 6 months old.
We are doing this study to see if CagriSema (Cagrilintide/semaglutide), a new medicine intended for the treatment of obesity, is safe for use in people living with obesity and cardiovascular disease. The study will also include some people with type 2 diabetes and/or chronic kidney disease.
You may qualify to participate if::
- You have had a stroke, a heart attack (myocardial infarction), or have poor circulation (peripheral
- arterial disease)
- You are 55 years of age or older
- You are living with obesity (BMI ≥ 30 kg/m2 )
- You can have type 2 diabetes and/or chronic kidney disease
- You are able to attend regular clinic visits and receive phone calls over
- a period of 3 years
Want to know more about the REDEFINE 3 study?
Call the study team at (205) 996-4015 or via email ccnrn@uab.edu
SAVITRI Study for Depression
Alzheimer’s Dementia and Agitation Clinical Study
Are you struggling to find a treatment for depression that works?
People who participate in RECOVER will receive VNS Therapy and all study-related care at no cost to them.
To join the RECOVER study, you must be 18 years or
older and:
1. Currently depressed
2. Have depression, or bipolar depression, that has lasted for at least two years or recurred several times
3. Have tried at least four types of antidepressant treatments and not found them helpful
4. Have Medicare Insurance
Ultraviolet light induced effects on the skin immune response
Seeking Gulf War Veterans for Brain Imaging Study
Healthy African American Men between the ages of 18 and 40 are needed for the Exercise and Beta-Blocker Study
STEP UP: Effect and safety of semaglutide 7.2 mg once-weekly in participants with obesity
Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
Are you a healthy African American between the ages of 18 and 60?
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.
Ultraviolet light induced effects on the skin immune response
Do you have Type 2 Diabetes and overweight
The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 78 week research study to look into how well semaglutide once weekly medicine works in participants with obesity and type 2 diabetes
Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
Tivanisiran for Dry Eye in Subjects with Sjögren’s Syndrome
You may be eligible to take part in the SYL1001_V Study if:
• You are 18 years or older
• You have a diagnosis of Sjögren’s
• Other entry criteria apply and your eligibility will be determined by
the study staff
If you decide to take part in the study, your participation could last approximately 3.5 months and consist of 5 to 6 visits to the study center. You will be reimbursed for each completed visit.
If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
Eligible enrolled participants will receive:
- Supervised exercise training at no cost
- Blood pressure medication at no cost
- Convenient parking at no cost
- Compensation for time
If you are interested, please call 205-996-3005 and mention The ACES Study or apply here -https://www.uab.edu/medicine/exercise/volunteer-clinical-trials/aces-trial.
Do you have Type 2 Diabetes? Tired of out-of-control blood sugar?
For more information, please contact us at: 205-224-2567, or freedom@uabmc.edu, or fill out this pre-screening form and we will get in touch with you: https://redcap.link/freedom
This study will last up to four years and will involve doing in-person visits every 6 months and filling out an online questionnaire from home every 3 months. At the first study visit you will be asked a series of questions or fill out a questionnaire about who you are (such as age, sex, or race), medical conditions that may affect the chances of having long-term effects of COVID-19, whether you have been vaccinated against COVID-19, and any symptoms you currently have. You will have a brief medical exam and we will also collect samples of your blood, saliva, stool, nasal swab and urine. Some participants will be invited for additional medical examinations and tests. You will be compensated.
Adult Volunteers with history of Chronic Obstructive Pulmonary Disease (COPD) needed for study
Can Intermittent Fasting or Calorie Restriction Slow the Aging Process? Healthy Volunteers Needed!
Help us find out by joining our study. The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting an exciting research study, in collaboration with Pennington Biomedical Research Center, to investigate whether intermittent fasting or calorie restriction (i.e., losing weight) can improve health and slow the aging process.
If you are randomly selected to do calorie restriction, you may lose weight by eating less. If you are randomly selected to do intermittent fasting, you will fast for 16 hours per day and eat dinner by 6 pm about 6 days per week (1 break day per week). We want you to be successful: the study provides intensive coaching and support to help you successfully lose weight or practice intermittent fasting.
To qualify, you should:
- Be 25-45 years old
- Have a BMI between 22-30 Calculate your BMI here
- Be healthy
- Not currently taking any medications or supplements for chronic conditions
- Not smoke, vape, or use tobacco products currently or within the last 6 months
- Not currently participate in a regular program of heavy physical activity (e.g., jogging, running, or riding fast on a bicycle for 30 minutes or more per day)
www.pbrc.edu\dialhealthuab
Healthy African American adults are needed for the NAUTICAL study
Are you a Female and Experiencing Urine leakage?
Adult Volunteers with history of Chronic Kidney Disease needed for study
Healthy Adult Volunteers ages 18-75 needed for study
Ultraviolet light induced effects on the skin immune response
Agitation Associated with Alzheimer’s Dementia Clinical Study
SAVITRI Study for Depression
The Kids Low Vision and Reading (KLoVR) study aims to better understand reading ability among children with permanent vision impairment.
Are you currently pregnant and planning to breast feed?
Do you wish there were another prolapse treatment option?
Have you or has someone you know had COVID?
Obese Adults Needed
Do you have Type 2 Diabetes? Are you 18-64 years old? Taking Metformin only to treat your Type 2 Diabetes?
Volunteers Needed for Research Study in Women with Irregular Menses and/or Abnormal Body or Facial Hair Growth
Recovering from a stroke? Still have problems with confusion, slow thinking, or memory?
Are you a Female and Experience a Loss of Urine with Urge and Frequency? Do you have Overactive Bladder with Urinary Leakage?
Does ultraviolet light alter skin immune responses?
Volunteers aged 50-75 years needed for a study on how salt in the diet relates to blood pressure
SAVITRI Study for Depression
Healthy volunteers between the ages of 18 and 40 are needed for the Exercise and Beta-Blocker Study
Do you have High Blood Pressure? Help us find out what is the right time to take blood pressure medication
Healthy volunteers between the ages of 14 and 45 needed for research on psychosis spectrum disorders
Healthy women needed for a research study
Do you have pain in one or both of your knees on most days?
Study of alcohol’s effect on mood and attention
Individuals with spinal cord injury needed for study
We are looking for individuals with spinal cord injury to participate in a home based exercise program for improving cardiometabolic health outcomes, such as body weight, blood sugar, cholesterol, and cardiovascular fitness. To qualify you must have a confirmed diagnosis of SCI at the cervical or thoracic level (C7-T12, classified as A, B, C, or D on the AIS scale), be at least 3 years post-injury, aged 19-65 years old. Participants will exercise for 16-weeks from home using an arm crank cycle ergometer and will receive $300 for completing the study. For more information, and to see if you might be eligible to join, please contact (205) 996-4114 or email at grdnfs@uab.edu
Do you have Type 2 Diabetes? Are you 18 years or older? Not currently taking Insulin ? Are you currently being treated with stable doses of daily or weekly GLP-1 receptor agonist, the treatment can be with or without any of the following anti-diabetic drugs with stable doses: Metformin, Sulfonylureasa , Meglitinides (glinides), DPP-4 inhibitors, Sodium-glucose co-transporter 2 inhibitors, Alpha-glucosidase-inhibitors, Thiazolidinediones The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 52 week research study comparing the efficacy and safety of once weekly IcoSema and once weekly semaglutide, Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
Do you have a spinal cord injury predating 3 years?
Are you a healthy person between the ages of 18 to 40 interested to improve cardiometabolic health?
DAY or NIGHT when is the right time to take blood pressure medication?? Help us to find out by joining our study
Do you wear glasses/contact lenses?
Minimum Eligibility Requirements: • You are 18- to 35-years-old. • You are currently wearing glasses/contact lenses. • You know how to use soft contact lenses. • You have had an eye exam within the last 2 years This study includes four to six visits, which will happen over ten weeks. If eligible, you will be compensated $20 to $40/visit with a maximum of $140 for your participation in the study. If interested, please contact Keyur Savla at 205-212-0355 or ksavla@uab.edu for additional information.
Do you have Urinary Leakage?
Do you have Urinary Leakage? If you are eligible (women 65 years or older), you will take part in a 12-week hip muscle exercise program, individualized sessions taught by a licensed physical therapist specialized in hip strength. The program offers 12 private sessions, alternating in-person and phone visits (a “home program”) Compensation will be provided. For more information, please call 205.934.5498.
Do you have treatment-resistant depression (TRD)?
A clinical research study is now enrolling eligible adults. The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an investigational medication when it is used alone in people with TRD. You may be eligible to participate if you: • Are 18 years of age or older • Have been diagnosed with TRD • Have not adequately responded to at least 2 different antidepressant treatments If you are interested, additional eligibility criteria will be assessed by the study doctor or staff. The commitment for the study is about 24 weeks. Qualified patients may receive investigational study medication and some study-required medical care at no cost. For more information about this study, you may visit www.clinicaltrials.gov and search “54135419TRD4005” or contact Kristine at 205-975-8542 or kristinepike@uabmc.edu.
Do you have depression with sleep problems?
A clinical research study is now enrolling eligible adults between the ages of 18-74 years of age. The purpose of the study is to evaluate the safety and effectiveness of an investigational medicine in people who have depression with sleep problems. Must have been diagnosed with depression, Have taken antidepressants in the past that did not work well for you and currently taking an antidepressant medication but still having symptoms of depression. Having difficulty falling asleep, or or do not feel rested the next day. If you are interested additional eligibility criterial will be assessed by the study doctor or staff. Qualified patients may receive study-related medical care and investigational study medication at no cost. In addition, reimbursement for study-related travel may be provided. Please contact Dana Green 205 975-6426