Clinical Trials

Interested in being part of vision rehabilitation research for healthy older adults aged 50-59 to lay the foundation of using a new device?

Here is an overview of what our study will involve!

The purpose of this study?

  • Calculate baseline data for Bioness Integrated Therapy System (BITS) and identify its clinical implications in treating visual impairments.
  • Compare the baseline data of Bioness Integrated Therapy System (BITS) to Dynavision for visual scanning.

Who are we looking for?

  • Healthy adults aged 50-59 without physical, visual, or cognitive impairment and with no history of seizures or balance problems.
  • Adults who are able to walk without assistive devices and are English speakers.

What would you have to do in 60 minutes?

  • Fill out a short survey for demographic data.
  • Quick functional screening of upper extremities.
  • Perform four tests on BITS.
  • Perform four tests on Dynavision.

Participants will receive a $25 gift card.

To participate in the study, please fill out this short survey:
https://uab.co1.qualtrics.com/jfe/form/SV_exEYGMKXxc230p0

For more information, please contact us at almulhim@uab.edu

Published in Clinical Trials

The UAB Sexual Health Research Clinic is recruiting women ages 18 to 45 to assess the safety, tolerability, and efficacy of a new vaginal suppository in women diagnosed with bacterial vaginosis (BV). Eligible participants will be compensated for each completed visit.

  • Are 18–45 years of age?
  • Are you pre-menopausal?
  • Have you been on birth control for the last 3 months and plan to continue use?
  • Are you currently having any vaginal symptoms?
  • Are you willing to abstain from sexual intercourse for at least one month?

Interested? Contact 205-934-8166 for more information.

Published in Clinical Trials

Do you want to make a difference for kids? More children are at risk for type 2 diabetes, and you can help us learn why.

Type 2 diabetes is diagnosed when the body has problems with high blood sugar levels. This can lead to serious health problems if not identified and treated early.

DISCOVERY is a study for children 9-14 years old who may be at higher risk of developing type 2 diabetes.

What will happen in the study?

  • In person and phone visits
  • Lab tests
  • Questionnaires
  • Physical exams
  • Glucose (blood sugar) monitors

Join families across the US to help us make a difference for all children and young people! This study does not involve medications and there is no cost to you. You will be compensated for your time in this study.

Contact us for more information:
205-517-1351
Discovery@uab.edu

Published in Clinical Trials
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.
Published in Clinical Trials
We are looking for volunteers to participate in a clinical study to advance lupus treatment.

If you are interested in seeing if you may qualify for an ongoing clinical study, please contact Christina Ndolo at cmndolo@uabmc.edu.
Published in Clinical Trials
Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.
Published in Clinical Trials
This study is looking for healthy children and adolescents, ages 2 to 17 years old that are interested in getting a pneumonia vaccine. Most children get a pneumonia vaccine in the first year of life. This research study will be testing a new version of the pneumonia vaccine that is designed to protect your child against additional strains of pneumonia. This means your child will receive one dose of the updated version of the vaccine, PCV21, or your child will receive PCV20, the currently administered pneumonia vaccine in the U.S. You will be expected to accompany your child for 2 clinic visits that will include your child’s vaccine injection and 2 blood draws. You must complete two telephone visits as well. The study duration is 6 months. Your child may qualify for enrollment if they are healthy and are ages 7 months to 23 months, but have never had a pneumonia vaccine. Compensation will be provided. If you are interested in enrollment or need more information, please contact Alexis, Misty, or Sama at 205-638-2629. Email as well at mlpurser@uabmc.edu
Published in Clinical Trials
Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
Published in Clinical Trials
If you are currently taking antidepressant medications but still struggle with depression, you may qualify for a new clinical research study. The study is evaluating an oral investigational medication for depression that can be taken with your current antidepressant medication. For more information and to see if you're eligible to participate, please call 205-975-8542 or 205-934-2484.
Published in Clinical Trials
September 25, 2024

Type 2 Diabetes Study

TRANSCEND-T2D-2 is a clinical research study for people with type 2 diabetes. This study will test if an investigational medicine (the medicine being studied) can help with blood glucose (sugar) and weight management compared with an existing treatment for type 2 diabetes. You may be able to join the research study if you are aged 18 years or older, have type 2 diabetes, have been taking 1500mg or more of metformin each day for at least 3 months (with or without SGLT2i), have a BMI of 25 or more, have HbA1c levels of 7.0% to 10.5%. For more information, please contact Tracie Thomas, RN, at 205-996-4015 or email tthoma@uab.edu
Published in Clinical Trials
Are you or is your child...
- Between the ages of 11 and 19?
- Feeling sad, down, or hopeless?
- Feeling guilty, tense, or irritable?

If so, you may be eligible to participate in a non-treatment research study.
Compensation provided for both parent and child, if applicable.
For more information, please contact the UAB Office of Psychiatric Clinical Research at (205) 934-2484.
-----------------------------------------------------------------------

We Need Healthy Adolescent Controls!
- Are you in good physical health?
- Are you between the ages of 11 and 19?
- Do you have NO history of Depression?

If so, you may be eligible to participate in a non-treatment research study.
Compensation provided for both parent and child, if applicable.
For more information, please contact the UAB Office of Psychiatric Clinical Research at (205) 934-2484.
Published in Clinical Trials
September 19, 2024

We Need Healthy Controls!

Are you between the ages of 18 and 60?
Do you have NO history of Depression?
Are you eager to participate in research?

If so, you maybe be eligible to participate in a non-treatment study. Compensation provided.

For more information, please call the UAB Office of Psychiatric Research at (205) 934-2484.
Published in Clinical Trials
September 19, 2024

Are You Depressed?

Are you...
- 18-60 years old?
- Feeling sad, down, hopeless?
- Experiencing increase or decrease in appetite?
- Experiencing loss of interest in activities?
- Having difficulty concentrating?
- Sleeping too little or too much?
- Wishing you were dead?

If so, you may be eligible to participate in a non-treatment research study. Compensation provided.

For more information, please call the UAB Office of Psychiatric Research at (205) 934-2484.
Published in Clinical Trials
September 18, 2024

Ladies We Need You!

Are you a cisgender woman over 18 who's been sexually active with a cisgender man in the past year?

If you haven't received a positive HIV test and haven't been on long-acting PrEP, you could be eligible to participate in our study.

Important: You CANNOT get HIV from participating in this clinical trial.Interested? Sign up today with the Alabama Vaccine Research Clinic at UAB to contribute to this vital research and get compensated for your participation. Call 205-934-7492 today.

Published in Clinical Trials
Opportunity to quit smoking cigarettes. Fully remote surveys.
 
If you smoke cigarettes every day, you may be eligible for a research study with the University of Alabama at Birmingham. The research study involves initial online screening, 8 contacts over 6 months and a chance to try varenicline, a prescription smoking cessation medication, or nicotine patches and lozenges. Compensation is available for those who are eligible and participate. Please follow the link below for more information and to see if you are eligible:

https://redcap.musc.edu/surveys/?s=8JWFT9XFY3FYR7Y3
Published in Clinical Trials
Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
Published in Clinical Trials
Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.
Published in Clinical Trials

About the Clinical Trial:

The purpose of this NIH funded trial is to examine the effects of three different diabetes treatments to determine if they improve night-time blood sugars.

This Trial Involves:

  • A screening visit that includes a blood draw, urine test and physical exam
  • Treatment with Metformin, Insulin Glargine (long-acting insulin) or the experimental drug Dorzagliatin which is FDA-approved for research, for up to 8 weeks
  • 2-4 inpatient visits/ including two overnight stays at the Clinical Research Unit at 15th floor of Jefferson Tower.

All visits to be completed within a three-month period. Study-related tests and procedures are provided free of charge. Participants will be compensated up to $2,500 for study completion. All Participants must be Diagnosed with type 2 DM and Not on any type of insulin therapy.

Please contact Kathryn Hollifield-Laumer at khollifield@uabmc.edu or co-investigators Chanel Mason at 205-934-1921 or cnmason@uabmc.edu, or Alaaeldin Hodhod at ahodhod@uabmc.edu.

Published in Clinical Trials
We are currently recruiting participants aged 18-30 with normal or corrected to normal vision and participants aged 18-89 with Macular Degeneration/Stargardt's Disease for a clinical research study that aims to understand how individuals learn to use their peripheral vision following the loss of central vision. This study is being conducted in the Civitan International Research Center and involves a total of 27 in-person visits over the course of 1.5 to 3 months. There are 2 MRI visits (1 at the beginning of the study and one at the end), 5 assessment visits (3 baseline assessments and 2 post assessments), and a total of 20 training sessions (in between the baselines and the post assessments). Compensation for full participation in this study is $350.

This is a great opportunity for all to gain experience participating in a clinical research study. All participation would not only contribute to advancing our understanding of perceptual learning and how the brain processes vision, but also holds the potential to improve outcomes for those with central vision loss.

If you or someone you know may be interested, please consider participating.

For more information or to express interest, please email mcmaxwell@uabmc.edu or text or call 205-410-4041, or visit go.uab.edu/brainstudy to sign up!

Thank you for your time and consideration!
Published in Clinical Trials

Participants between the ages of 35 and 65 are needed for this study. The purpose of the study is to fill in what we don’t know about how schizophrenia affects people as they get older. We want to find out what we can do to help older individuals with schizophrenia live better lives. The study includes 4 visits over the course of two weeks. The screening visit will take 2 hours. The first study visit will take 3 hours. The second study visit will take 2 hours. The third study visit will take 9 hours. This study will include: a clinical interview, cognitive batteries, questionnaires and assessments related to your daily and psychiatric functioning, two 90 minute MRI scans of your brain, a fasting blood draw, and a urine drug screen and pregnancy test (for females). Compensation is up to $310. TO SEE IF YOU QUALIFY PLEASE CONTACT (205) 934-8203.

Published in Clinical Trials

If you experience urine leakage and you are 65 years or older, you may qualify for the study.

We are assessing whether hip exercises can improve pelvic floor muscle strength and urinary leakage.

You will serve as a “control.” At the visit, you will undergo a routine examination (10 minutes) for urinary leakage and answer questionnaires (10-15 minutes).

You will come to clinic for two visits.

$100 ($50 at each visit) compensation will be provided.

For more information, please call 205.934.5498.

Published in Clinical Trials
Join us at the Alabama Vaccine Research Clinic at UAB! We are looking for volunteers to join a Phase 1 clinical trial to test the safety and immune response of a new HIV vaccine. The study is for adults who are HIV-negative, in good health, and aged 18 to 55. Procedures will include blood draws and injections of the study vaccine, as well as the collection of white blood cells through a procedure called leukapheresis. Participants will be compensated for their time in this study. The study vaccine will not give you HIV. If you are interested, please call 205-934-6777 or email avrc@uabmc.edu. You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/.
Published in Clinical Trials
Our study is looking for physically active and inactive postmenopausal women of Black or White race. We are testing the impact of race, exercise habits, and living conditions on heart disease risk in postmenopausal women. Participation only involves two, one-hour long visits to the UAB Center for Exercise Medicine and offers compensation up to $200. If you are interested in participating, please call McKenna Tharpe at (205) 996-3005.
Published in Clinical Trials
Participants Needed. We are recruiting individuals who have experienced a stroke and are able to walk with minimal restriction and also age similar control participants that have NOT experienced a stroke between the ages of 18-89 for a research study on walking. The focus of this study is to understand how to optimize the delivery of a combined strength and aerobic training regimen to individuals with post stroke hemiparesis and reduce overuse and inefficiencies associated with the unaffected leg while walking. If you qualify, your participation in the study will span a single study visit, with a total time commitment of 3 hours. You will be compensated for your time. Please e-mail Christopher Hurt at cphurt@uab.edu or contact him by phone at 205-934-8517 if you are interested.
Published in Clinical Trials
What is the study?

This study aims to characterize social cognition and motivation in HIV and to determine the effect of social cognition and motivation on quality of life in HIV.

Are you eligible?
  • Older than 40 years
  • No Neurological Deficits
  • No History of Psychotic Symptoms
  • No diagnosis of a mood disorder
  • No Diagnosis of HIV
  • English Speaking

How many visits?
Pre-Screening interview (2 hours)
Behavioral Testing Sessions (6 hours)
MRI Scans (4 hours)

$25 per hour up to $312.50

Interested?
Contact us: 205.934.8203 NLSB.uab@gmail.com
Published in Clinical Trials
Study Information:
  • Are you 18-60 years of age living with HIV, and want to be a part of a vaccine study?
  • Is your viral load suppressed/undetectable?
  • Are you able to receive a vaccine?
  • Are you generally healthy?
  • Are you willing to temporarily stop taking antiretrovirals?

You may qualify for a study looking at testing an experimental HIV vaccine with an experimental adjuvant to see how the immune responses change among participants who do an antiretroviral analytical treatment interruption (ATI) compared to those who do not. Compensation at each study visit will be provided for time and travel. Transportation services are also available upon request. If interested, please email sspaulding@uabmc.edu.

Published in Clinical Trials
• Are you 18-70 years of age living with HIV, and want to be a part of a curative study?
• Is your viral load suppressed/undetectable?
• Are you able to receive an infusion or injection?
• Are you generally healthy?
• Are you willing to temporarily stop taking antiretrovirals?

You may qualify for a HIV treatment study looking at an investigational way to effectively clear the HIV virus in areas of the body that standard antiretroviral treatment is unable to reach. You will receive one of two potential intervention methods. One intervention method is a broadly neutralizing antibody that is given to control growth of the HIV virus and to increase the body’s immune system response. The second intervention method is an injection (IL-15 Superagonist) designed to awaken the immune system, activate any dormant HIV virus, and then kill the virus. The duration of this study is approximately 84-112 weeks pending on which intervention method you receive. There is compensation at each study visit for time and travel.


Contact: If interested, please email kspraggins@uabmc.edu or call 205-934-9346
Published in Clinical Trials
Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.
Published in Clinical Trials
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.
Published in Clinical Trials
Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
Published in Clinical Trials
You may be eligible to participate in a research study: If you are a healthy female, between age of 18-50, still having a regular menstrual cycle & you are NOT on hormonal birth control (birth control pills or shots (i.e. Depo shot) or IUD, like Mirena). And, if you are willing to undergo an endometrial biopsy procedure and blood draw.

Participants will be compensated a total of $200. Only requires 2 visits.

For information, call us at 205-934-5498 or email: urogynecology@uabmc.edu
Published in Clinical Trials

A Phase 3, Randomized, Multicenter, Open-label Study to Investigate the Efficacy and Safety of Retatrutide Once Weekly Compared with Semaglutide Once Weekly in Adult Participants with Type 2 Diabetes and Inadequate Glycemic Control with Metformin with or without SGLT2 Inhibitor (TRANSCEND-T2D-2)

TRANSCEND-T2D-2 is a clinical research study for people with type 2 diabetes.
This study will test if an investigational medicine (the medicine being studied) can
help with blood glucose (sugar) and weight management compared with an existing
treatment for type 2 diabetes.

  • Are aged 18 years or older
  • Have type 2 diabetes
  • Have been taking 1500mg or more of metformin each day for at least 3 months (with or without SGLT2i)
  • Have a BMI of 25 or more
  • Have HbA1c levels of 7.0% to 10.5%

To see if you qualify please contact at 205-996-4015, 205-934-5564 or via mail at tthoma@uab.edu or ccnrn@uab.edu
Published in Clinical Trials
If you’ve been feeling stuck and longing for relief, you may be eligible to receive dedicated medical attention, an investigational therapeutic and compensation for your involvement in an innovative research study.

We're conducting clinical research in depression to learn how individuals’ brain biology impacts response to treatment, with the goal to help people find relief faster. You do not need to already have a diagnosis to participate.

If you’re currently taking medication, you are likely still eligible for our studies and don’t have to stop your existing treatment regimen.

For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.
Published in Clinical Trials
Major Depressive Disorder is a mental health condition characterized by periods of low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. The purpose of this clinical research study is to evaluate the safety and effectiveness of an investigational drug for Major Depressive Disorder, also known as Major Depression. Study participation may include several clinic visits over a period of up to 5 months with an opportunity to conduct some visits either virtually or in-clinic. Qualified participants will receive compensation for their time.

For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.
Published in Clinical Trials
Are you:
• A woman on parole, probation, or recently released from prison or jail?
• A woman who has used drugs?
• Interested in learning about a way to protect yourself against HIV?

You may qualify for a paid research study at the University of Alabama at Birmingham, in partnership with Yale University.
• Participate in confidential study interviews at our research office.
• Earn $50 for each interview, up to $225 for participating in the study.

Fill out our contact survey at: https://yalesurvey.ca1.qualtrics.com/jfe/form/SV_d7sAjr6GDsjiJng?Q_CHL=qr

Or you may call: (205) 934-2851 or Email: AthenaStudy@uabmc.edu
Published in Clinical Trials
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.
Published in Clinical Trials
Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
Published in Clinical Trials
Help us find out by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.
Published in Clinical Trials
Researchers from the UAB School of Optometry are currently recruiting those with dry eyes to participate in a research study looking at how a part of your eye's immune system called the complement system is involved in dry eye disease. If eligible, you will be asked to have your eyes evaluated three times, each visit being 3 to 17 days apart. Visit will last between 30 to 90 minutes. You will receive $150 if you are eligible for the study and complete all study procedures. NOW RECRUITING SUBJECTS WITH SJOGREN'S SYNDROME.

If you are interested in participating in this research and want to know more about the study, kindly follow this link to fill out our recruitment survey.
Published in Clinical Trials
University of Alabama at Birmingham is seeking cigarette smokers who would like to quit smoking for participation in a scientific research study. The research study involves free counseling and treatment provided in a comfortable, supportive setting. The study may involve ingestion of psilocybin, a psychoactive substance found in psychedelic mushrooms that have been used as a sacrament in various cultures. Some research studies have suggested that psychedelics, when administered under interpersonally supportive and well-prepared conditions, may be effective in helping people overcome addictions.

Questionnaires, interviews, and biological measures of smoking will be used to assess the treatment's effects on mood and smoking. Participants will be compensated $50 per session. If you would like to discuss the possibility of volunteering, please call 205-996-1198, or go to www.quitsmokingbaltimore.org for more information about the study and to complete the online study prescreener for the UAB site. Confidentiality will be maintained for all applicants and participants.

Volunteers must be 21 years of age or older, and must live within travel distance of the study site in Birmingham.
Published in Clinical Trials
There is an ongoing psychedelic clinical research study evaluating the safety and efficacy of an intranasal study drug for patients with treatment resistant depression.

To qualify patients need to be 18-75 years of age, failed to respond to an adequate dose & duration of at least 2 medicines for depression. If currently taking antidepressants, willing and able to discontinue.

If eligible, study participants will be expected to abstain from illicit drugs for the duration of the trial & attend all study visits & follow instructions from the study doctor. Study examinations will be at no cost to you.

For more information please contact 205-996-1198 or spremani@uab.edu
Published in Clinical Trials
Treatment for Urge Urinary Leakage: BEST Study

This study will compare the effectiveness of two different treatments for urge urinary incontinence (UUI). One treatment is Botox injections in the bladder, and the other is an oral medication (mirabegron or vibegron).

Participants compensated up to $425.

For more information about this study, please email or at urogynecology@uabmc.edu or 205-934-5498.
Published in Clinical Trials
BrainREAD is recruiting autistic and typically-developing children, ages 7-13, with reading comprehension difficulties to participate in an MRI study that includes a free reading intervention through Lindamood-Bell Learning Processes. We are also recruiting typically developing children with no reading difficulties to participate. Participation involves a pre and post session which are broken up into two days each. Day 1 consist of neuropsychological evaluations and Day 2 is the MRI scan. Participants can be compensated up to $250 for both testing sessions. If interested, please call 205-202-0616, email cas-cbalab@uab.edu. or visit https://sites.uab.edu/cbra/ to fill out our contact form.
Published in Clinical Trials
February 12, 2024

WE NEED YOU!

We may have the right sexual health research study for YOU. Participants will be compensated.

Call us TODAY at 205-934-8166.
Published in Clinical Trials
Our research team is currently conducting an exercise training study in children and adolescents with cerebral palsy who can walk.
  • You must be 11 - 21 years old.
  • You will be asked to walk, jump, step, and do exercises.
  • Eligible participants will have multiple visits and can be compensated up to $430 depending on your tests.

To learn more about the study, please call (205) 774-8448 or email phuong@uab.edu.
Published in Clinical Trials
Are you experiencing pain due to endometriosis? Please consider joining a research study looking at a potential new medication to help women experiencing moderate to severe endometriosis-related pain. Study medication provided at no cost. Participants receive compensation for each visit completed. For more information please call 205-934-1322 or email slangan@uabmc.edu.
Published in Clinical Trials
About 12% of people in the United States are currently living with herpes simplex virus type 2 (HSV-2) genital herpes. Moderna is sponsoring the Vantage Trial, a clinical trial looking at the safety and immune response of an investigational vaccine to potentially treat HSV-2. Your participation may help advance research of an investigational treatment option for HSV-2—one that aims to treat genital herpes and relieve the burden of daily medication.

If you are living with HSV-2, you may be eligible to join. To learn more, contact the UAB Sexual Health Research Clinic at 205-934-8166.
Published in Clinical Trials
Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at, genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
Published in Clinical Trials
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.
Published in Clinical Trials

We are looking for people with knee osteoarthritis to participate in a study to examine whether a diet intervention can reduce pain and improve quality of life. The commitment to this study will last approximately 7 weeks and include the following:

  • Five (5) visits to UAB where you will fill out questionnaires, complete a DEXA scan, blood draw or Quantitative Sensory testing. These visits will last anywhere from 1-3 hrs.
  • Six (6) weeks on a randomized diet where we will provide three (3) meals and two to three (2-3) snacks per day.

Participants must:

  • Be currently suffering from pain related to knee osteoarthritis
  • Be free from other serious health conditions (diabetes, cardiovascular disease, eating disorders, metabolic disease)

Participants will receive up to $250 for completing the study and meals will be provided. Please contact DIRECT at DIRECTPAIN1@gmail.com (205) 834-3628. Leave a short message with your name and number.

Published in Clinical Trials
DAY or NIGHT, when is the best time to take your blood pressure medication?

Help us find out by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.
Published in Clinical Trials
Healthy participants needed if you are:
  • 18-75 years old
  • No diagnosis of any neurological disorders or psychiatric problems
  • No history of problematic drug/alcohol use in the last 3 months
For more information and to determine eligibility, please call the Neuroscience Laboratory of Social Behavior at (205) 934-8203 or email nlsb.uab@gmail.com.
**Compensation is provided**
Published in Clinical Trials
If you are 14 to 39 years of age, less than 18 weeks pregnant, and planning to deliver at UAB, you may be eligible for our education-based study. This study focuses on learning about healthy behaviors and how to make positive changes that could lead to a healthier pregnancy for you and your baby. Four study visits are spread out over 13 weeks during pregnancy, and one brief post-delivery visit where study staff visit participants in the post-partum unit. Participation includes a one-on-one education session, answering several questionnaires, and collecting lab work, including blood, mouth swabs & self-collected urine samples, and vaginal swabs. Also, three times during the study, participants are given a packet to collect two swabs at home and mail them in. Participants are compensated $230 for completing all study visits and specimens. For more information, please call Leslie Black at 205-919-5945, email PrPrepStudy@uabmc.edu, or text 256-934-4991.
Published in Clinical Trials
UAB is looking for participants for a study investigating the effects of a new study medication on symptoms of fibromyalgia. We are looking for women aged 25-65 who are diagnosed with fibromyalgia OR are experiencing chronic widespread bodily pain. Participants will come to UAB for 7 study visits over a 3-month period. Participants will be compensated for completing all study visits.

Please call 205-996-1198 if interested.
Published in Clinical Trials
The purpose of this study is to evaluate if COPD is caused by exposure to heavy metals. This study will include a medical history review, a brief physical examination, spirometry, exhaled breath condensate, urine sample, blood collection, and a bronchoscopy/bronchoalveolar lavage procedure. Those who qualify will receive compensation for their time. Participation is voluntary. Participants in the study must: be 18 to 65 years of age; live in defined zip codes, 35207, 35217, 35214; and fulfill other eligibility criteria to include a medical and medication history for evaluation. For more information, please call (205) 996-1769 or email uabsuperfund@uabmc.edu.
Published in Clinical Trials
The purpose of this research study is to analyze cells and fluid obtained from the lungs and determine mechanism(s) by which these cells are impaired in their ability to reduce the severity of lung infections. This study will include a medical history review, a brief physical examination, spirometry, and a bronchoscopy/bronchoalveolar lavage procedure. Those who qualify will receive compensation for their time. Participation is voluntary. Participants in the study must: be 18 to 65 years of age; live in defined zip codes, 35207, 35217, 35214; and fulfill other eligibility criteria to include a medical and medication history for evaluation. For more information, please call (205) 996-1769 or email uabsuperfund@uabmc.edu.
Published in Clinical Trials
We are asking you to take part in this research study because you are a resident of North Birmingham or Tarrant and may have exposure to arsenic due to industrial activity in the area. This research study is now enrolling adults within the zip codes, 35207 and 35217. After confirming enrollment eligibility, those who qualify will be randomized to receive either folic acid supplementation or a placebo at no cost. We will collect a brief medical and medication history, collect samples of urine and blood, perform spirometry testing, and complete a respiratory questionnaire.

Participation is voluntary, and you will be compensated for your time. Participants in the study must: be 18 to 65 years of age; a resident of 35207 or 35217 zip codes; not currently pregnant or currently taking folic acid; and fulfill other eligibility criteria. For more information, please call (205) 996-1769 or email uabsuperfund@uabmc.edu.
Published in Clinical Trials
If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
Published in Clinical Trials
People with dementia sometimes do not cooperate with care. They may refuse to bathe, change clothes, or refuse to take medications. The purpose of this study is to test if a caregiver coaching program can help family caregivers better manage refusal behaviors by increasing their use of problem-solving strategies and decreasing any negative coping strategies. To participate, you must be at least 18 years old, live in Alabama, and live with and provide unpaid care to a family member with dementia who refuses help or care. You will receive 9 1-hour coaching sessions over Zoom at a time that works for you. You will be asked to complete surveys and questionnaires, and you will be paid for doing these things. All surveys and questionnaires are completed online. There is NO travel to UAB. Please email CURBIT@UAB.EDU for more information.
Published in Clinical Trials

DAY or NIGHT, when is the best time to take your blood pressure medication?

Help us find out by joining our study at UAB by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

Published in Clinical Trials
UAB researchers are looking for adults (ages 25-65) who are suffering from demoralization - feelings of hopelessness or meaninglessness - to participate in a research study evaluating a novel medication.

To see if you qualify call 205-379-7527.
Published in Clinical Trials
CURB-2 is an abbreviation we use to refer to this study because there was a similar study completed and published in 2016 called CURB, which stands for Cocaine Use Reduction with Buprenorphine. The results from that study showed that using injectable naltrexone and sublingual buprenorphine was beneficial to participants on high doses of the medication. This study will give injectable naltrexone and injectable buprenorphine to make sure medication doses are consistent to confirm potential benefits.

There are no approved treatments specifically for cocaine use disorder. We are looking for adults (18-65 years of age) who are using cocaine and who are interested in reducing or stopping their use. The purpose of our study is to test a combination of two medications for 2 months as a possible treatment for cocaine use disorder.

This study includes the use of a placebo, which looks like the medication we are testing but does not include any active medicine. Study medication and assessments will be provided to participants at no cost. Participants will receive compensation for their time and efforts.

Study information will be kept strictly confidential. Your privacy is important to us.

Call us for more information at 205-996-0211 or email us at curb2study@uabmc.edu
Published in Clinical Trials
If so, they could be a part of a study that looks at the long-term effects of receiving the COVID-19 vaccine. Healthy children or children with conditions affecting their immune systems are eligible to enroll. Blood samples and nasal swabs will be collected every 2 months for one year. An echocardiogram and EKG will also be required at the second visit. Compensation for participation is available. To learn more, contact the UAB study team: 205-638-2629 or mlpurser@uabmc.edu
Published in Clinical Trials
Congenital CMV infection is the most common infection passed from the mother to baby during pregnancy. It is also the most common non-hereditary cause of hearing loss and brain damage in children. You or your child will have 3 injections, several months apart. You will have approximately 11 clinic visits over the 18 month study period. Saliva swabs, urine, and blood samples will be required. Compensation for participation is available. To learn more, visit CMVibeTrial.com or contact the UAB study team: 205-638-2629 or mlpurser@uabmc.edu
Published in Clinical Trials

Help us find out by joining our study at UAB by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

Published in Clinical Trials
Are you tired of constantly fearing urinary leakage? Say goodbye to embarrassing accidents and take control of your life! We believe in living life to the fullest without worrying about Urgency Urinary Leakage. Compensation is provided.

Call us today at (205) 934-5498 to join our urogynecology clinical trial and find the perfect treatment plan tailored to you.
Published in Clinical Trials
The UAB Department of Psychiatry is recruiting healthy adolescent participants for a clinical research study. The study will compare healthy adolescents and adolescents with functional seizures (FS).

To participate in this research, you must:
- be 11 to 18 years old
- have no diagnosed medical conditions
- have a parent/guardian available to participate in lab visits

If you choose to participate in the study, you will be part of the healthy control group. You will come for 2 lab visits 13 weeks apart. The adolescent can be compensated up to $100 total. To find out more about the study, call 205-975-4205 or email pedshealthlab@uabmc.edu.
Published in Clinical Trials
You may be eligible to participate if you identify as female, White or African American, are aged 35-65, and have a BMI of 30+. Participants will receive $50 as thanks for their participation.

This study is a 5-hour workshop delivered in groups that is based on principles of acceptance and commitment therapy (ACT). Participants will learn new skills to facilitate the adoption of healthy lifestyle behaviors, such as eating a healthy diet and exercising regularly. These skills include identifying values, tolerating the discomfort associated with lifestyle change, identifying self-sabotaging thoughts, and more!

For more information, please contact Andrea at andrealdavis@uabmc.edu or 205-206-9434.
Published in Clinical Trials
Do you identify as an individual living with cancer and part of the LGBTQIA+ community or a care partner of someone in this community? A research lab at the University of Alabama at Birmingham is looking to learn about the day-to-day experiences of LGBTQIA+ cancer survivors and their care partners. We are interested in how individuals manage difficult situations related to their respective roles in their relationships. Individuals living with cancer often encounter stressful situations that can impact their mood and any additional stressors from living as a sexual or gender minority with a lack of resources adds an increased risk of experiencing stressful situations. The goal of this work is to develop resources that better support the well-being of LGBTQIA+ individuals living with cancer and their care partners. This study will take place FULLY online with completion of daily surveys. All participants will be compensated. To learn more about our study contact us at starlab@uab.edu
Published in Clinical Trials
The University of Alabama at Birmingham (UAB) is inviting Hispanic or Latino/a family caregivers to complete short surveys for our study. Your answers will help us understand your daily experiences and develop services to better support caregivers in the community. You will be paid for your time. Your answers will remain anonymous. To learn more contact us at starlab@uab.edu or call Lorelí Alvarez at 205-996-0339.
To be contacted by the research team register here: https://uab.co1.qualtrics.com/jfe/form/SV_d3TmeAlFEPBRmNU

¿Cuidas de un familiar con problemas de memoria o demencia/enfermedad de Alzheimer?
La Universidad de Alabama en Birmingham (UAB) está invitando a cuidadores familiares hispanos y latinos para que completen breves encuestas para nuestro proyecto. Tus respuestas ayudarán a comprender mejor las experiencias del día a día y a desarrollar servicios para apoyar mejor a los cuidadores familiares de la comunidad. Les compensaremos por su participación. Sus respuestas permanecerán anónimas. Para saber más escribe a starlab@uab.edu o llama por teléfono al 205-996-0339 y pregunta por Lorelí Alvarez.
Para ser contactado por el equipo de investigación haga click aquí: https://uab.co1.qualtrics.com/jfe/form/SV_d3TmeAlFEPBRmNU
Published in Clinical Trials
Study of an investigational device for improving glycemic control in adults with type 2 diabetes. It is an external headset that attaches behind the ears to deliver a small electrical current to the vestibular system – the balance system in the inner ear. Previous research suggests that activating the vestibular nerve may cause a reduction in body fat but also improve glycemic control. The aim of the study is to evaluate whether frequent use of the device, along with a lifestyle modification program, can improve glycemic control. Contact 205-996-4015 or 205-996-4020 for more information.
Published in Clinical Trials
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.
Published in Clinical Trials
Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
Published in Clinical Trials
We are actively recruiting for research studies focused on women with one of the following conditions:

1. Accidental bowel leakage (fecal incontinence)
2. Urinary leakage (urinary incontinence)

Please call 205-934-5498 to learn more about these studies.
Published in Clinical Trials
If you are currently pregnant, 18 or older, planning to deliver at UAB, and planning to breast feed, you may be eligible for our study!

This study focuses on better understanding breast milk composition, the presence or absence of CMV in breast milk, and its possible transmission to babies. CMV is a common virus that most people in the US are infected with by adulthood. Participants will meet with study staff once a month for six months to collect non-invasive samples and answer a questionnaire. Samples collected include oral swabs from you and your baby, a small quantity of breast milk and a skin swab from you, as well as a urine and stool sample from your baby. Participants will be compensated up to $300 for completing the study visits and providing samples. Eligible participants may also qualify for additional sub-studies for additional compensation up to $800.

For more information, please contact us via phone or email at:
Phone: 205-975-3752
Email: milk@uabmc.edu
Published in Clinical Trials
BrainREAD is recruiting children with autism and typically-developing children, ages 7-13, who have reading comprehension difficulties to participate in an MRI study that includes a free reading intervention through Lindamood-Bell Learning Processes. Participation involves two sessions each of which are broken up into two days - one day of neuropsych assessments and one day for the scan. Participants can be compensated up to $125 for the first scan and tests with an additional $125 for the follow-up scan and tests, 12 weeks later. If interested, please call 205-202-0616, email cbralab@ua.edu or visit cbra.ua.edu/brainread.html and fill out our contact form.
Published in Clinical Trials
If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
Published in Clinical Trials
Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.
Published in Clinical Trials
The UAB TRIP Lab is studying the effects of concussion on driving among adolescents and young adults, from acute post-injury to symptom resolution. We are in search of 16-24 year olds who have had a concussion within the last 10 days AND who have NOT had a concussion (control group) to participate in a longitudinal study. Participants will visit UAB once per week, where they will drive in a fully immersive, state-of-the-art driving simulator and complete some cognitive and/or balance tasks. Participant will also complete surveys throughout the week. Participants are compensated up to $610 for their time. If interested, please contact the UAB TRIP Lab, (205) 975-9440 | TRIPLAB@UAB.EDU
Published in Clinical Trials
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.
Published in Clinical Trials
The Functional Outcomes from Diet in Multiple Sclerosis (FOOD for MS) study will test whether eating healthy foods and losing weight can improve physical function, pain, fatigue, mood, and sleep in adults with relapsing-remitting or secondary progressing MS. We will also explore the how diet impacts inflammation, immunity, and metabolic biomarkers that may contribute to MS symptoms and progression. Eligible participants must be 18-65 years old, diagnosed with Relapsing Remitting Multiple Sclerosis or Secondary Progressive Multiple Sclerosis, and be able to travel to one of our two study sites, Birmingham, Alabama or St. Louis, Missouri three times points over 8 months. Participants will be compensated $150 for completing all study visits and have their groceries provided for the length of the 8 month study. Please contact Kathryn Green at kathryngreen@uabmc.edu or by phone 205-319-1424 or Meghan Taylor at meghan13@uab.edu for more information and to see if you qualify.
Published in Clinical Trials
Do you have a history of kidney stones?
If you are 18 or older with a history of calcium oxalate kidney stones, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
Published in Clinical Trials
f you are 18 or older and in good health, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
Published in Clinical Trials
Healthy adults needed for a study on vitamin C
If you are 18 or older and in good health, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
Published in Clinical Trials
Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at, genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
Published in Clinical Trials
The benefits of taking statins for older adults without heart disease are not fully understood. About 20,000 older adults along with a team of researchers and clinicians across the country will be involved in the PREVENTABLE study. The purpose is to learn if taking a statin is helpful for older adults. Are you a good fit for PREVENTABLE? Contact the study team to find out.

See the website at www. preventabletrial.org

Please call or text: (205) 224-2567 or email destinytaylor@uabmc.edu if you are interested.
Published in Clinical Trials
Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
Published in Clinical Trials
We are looking for people who identify as trans or cisgender, are 18-65 years of age and would like to take part in a research study examining the impact of gender identity, hormone levels and sex assigned at birth to pain sensitivity and immune cell activity. The commitment to this study will last approximately 3 hours where you will fill out questionnaires, have a single blood draw and take part in pain sensitivity testing. Participants must: Be free from certain health conditions (HIX+, cardiovascular disease, uncontrolled hypertension). Participants can be on HRT (hormone replacement therapy) or not. Participants will receive up to $100. To find out more about this study, call 205-834-3625 or email shinestudyuab@gmail.com.
Published in Clinical Trials
March 01, 2023

DECLARE Study

We are recruiting healthy men & women who are between 55-75 years of age AND have hypertension for the DECLARE Study.

The purpose of this research study is to examine the effects of 10 weeks of exercise on the brain. DEcreasing Cognitive Loss and Vascular Rarefaction with Exercise (DECLARE) is focused on the elucidation of exercise effects on brain health and the way by which exercise mitigates age-related growth factor deficiencies, hypertension and cognitive decline.

To participate in this research, you must:
– have high blood pressure
– be between 55-75 years of age
– be healthy (Ok to be on medication)
– not currently exercising

Please contact us at 205-996-5592 or use the following link to complete the 5 minute screening questionnaire: https://uab.co1.qualtrics.com/jfe/form/SV_6FigP3lOJYdvl9c
Published in Clinical Trials
February 22, 2023

Lung Health Cohort

One Breath Matters.

Are you or someone you care about age 25-35 and interested in lung health? Join the landmark Lung Health Cohort Research Study to improve the health of future generations.

The pioneering NIH-funded study will follow 4,000 young, healthy adults to paint a clearer picture of lung health and the factors involved in predicting and preventing lung disease.

To learn more, visit: Lung.org/lung-study 
Published in Clinical Trials
The University of Alabama at Birmingham (UAB), in collaboration with Novo Nordisk, is conducting a 3-year research study to see if CagriSema, an investigational weekly medicine being studied for the treatment of obesity is also safe for the heart and blood vessels.

We are doing this study to see if CagriSema (Cagrilintide/semaglutide), a new medicine intended for the treatment of obesity, is safe for use in people living with obesity and cardiovascular disease. The study will also include some people with type 2 diabetes and/or chronic kidney disease.

You may qualify to participate if::
  • You have had a stroke, a heart attack (myocardial infarction), or have poor circulation (peripheral
  • arterial disease)
  • You are 55 years of age or older
  • You are living with obesity (BMI ≥ 30 kg/m2 )
  • You can have type 2 diabetes and/or chronic kidney disease
  • You are able to attend regular clinic visits and receive phone calls over
  • a period of 3 years

Want to know more about the REDEFINE 3 study?
Call the study team at (205) 996-4015 or via email ccnrn@uab.edu
Published in Clinical Trials
If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
Published in Clinical Trials
Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.
Published in Clinical Trials
The RECOVER study was designed in partnership with many of the nation’s top experts in treatment-resistant depression, and approved by Medicare, to provide additional evidence of the benefit of VNS Therapy. If the results confirm previous studies, Medicare and other insurers may start to cover it.

People who participate in RECOVER will receive VNS Therapy and all study-related care at no cost to them.

To join the RECOVER study, you must be 18 years or
older and:

1. Currently depressed
2. Have depression, or bipolar depression, that has lasted for at least two years or recurred several times
3. Have tried at least four types of antidepressant treatments and not found them helpful
4. Have Medicare Insurance
Published in Clinical Trials
We are currently seeking Gulf War Veterans to participate in a brain imaging research study. Healthy Gulf War Veterans and Veterans with chronic health problems are invited to participate. Participation involves 1-2 visits to UAB for 2.5 hours total. Participants undergo MRI brain scan, blood draw, and complete several questionnaires. Participants who complete the study receive $150 compensation. Please email chloej@uab.edu or call 205-434-1502 for more information and to find out if you're eligible.
Published in Clinical Trials
You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy African American men having no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
Published in Clinical Trials

Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested

Published in Clinical Trials

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.

Published in Clinical Trials
Are you 19 years or older? Are you being treated with lifestyle changes or treated with one or more oral diabetes medications ?

The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 78 week research study to look into how well semaglutide once weekly medicine works in participants with obesity and type 2 diabetes

Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
Published in Clinical Trials
Clinical Study for Patients with Dry Eye Associated with Sjögren’s Disease. If you are an adult with Dry Eye Disease associated with Sjögren’s, you may be eligible to take part in a clinical research study being conducted by Sylentis S.A.U. The purpose is to compare the study eye drop to placebo (eyedrop without medication) in treating the signs and symptoms of Dry Eye associated with Sjögren’s.

You may be eligible to take part in the SYL1001_V Study if:
• You are 18 years or older
• You have a diagnosis of Sjögren’s
• Other entry criteria apply and your eligibility will be determined by
the study staff


If you decide to take part in the study, your participation could last approximately 3.5 months and consist of 5 to 6 visits to the study center. You will be reimbursed for each completed visit.
Published in Clinical Trials
Page 1 of 4