Clinical Trials

Participate in nationwide study to understand why some people have prolonged symptoms (referred to as long COVID or post-acute sequelae of SARS-CoV-2, also called PASC) or develop new or returning symptoms after the acute phase of SARS-CoV-2 infection. We need COVID-19 survivors from the Birmingham and Mobile, Alabama, and New Orleans, Louisiana, areas. If you are over 18 years old, not pregnant, and would like to take part in UAB’s study, email COVIDResearch@uabmc.edu to find out more.
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August 08, 2022

Obese Adults Needed

Obese adults, age 25 to 45 years old, are needed to determine if the timing of salt intake affects blood pressure throughout the day. This study involves 12 visits over 8 weeks. Participants will be compensated for participation. You may not be eligible to participate if you have significant health problems, are pregnant, or are taking certain medications. Please contact Alexis at aelambert@uabmc.edu or call (205) 582-7761 if you are interested in learning more about this study.
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The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 52 week research study to look into how well semaglutide once weekly medicine works at different doses in people with type 2 diabetes and overweight Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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Are you a Female and Experience a Loss of Urine with Urge and Frequency? Do you have Overactive Bladder with Urinary Leakage? To find out if you are eligible, please call at 205-934-1777 or email Dr. Russell Stanley at russellstanley@uabmc.edu. $200 Compensation will be provided.
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The UAB Epilepsy Center is looking for participants aged 40 and older for a brain imaging study. Eligible individuals will have a diagnosis of depression, anxiety, or PTSD. The study involves one visit at UAB Highlands Hospital and will last up to 2.5 hours. Participants will undergo a brain MRI, complete questionnaires, and provide a small amount of blood. You will be compensated $100 for completing the visit. If interested, please contact Dr. Christina Mueller at (205) 671-4355 or cm1@uab.edu.
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Do you have infrequent or irregular cycles? or Do you have excessive hair growth on your upper lip, chin, chest, abdomen, buttocks, or back? If you answered YES to any of the questions above you may qualify for this study. Benefits: Free physical exam, labs and ovarian imaging, Receive up to $600 for complete participation in the study. Help to improve our understanding of women's health. For More information Please call (205) 934-0877 or email slangan@uabmc.edu
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Has your child been diagnosed with non-alcoholic fatty liver disease (NAFLD)? If so, he/she could be eligible to participate in a 6-month research study that is investigating whether changes in diet composition affect various health outcomes in adolescents with non-alcoholic fatty liver disease. You will receive diet counseling and groceries at no cost. Compensation for participation will also be provided. For more information or to enroll in our study, please email alexlm@uabmc.edu or call 205-934-6299. Participants cannot be claustrophobic.
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If you are 19 or older and an exclusive vaper (meaning only vaping and no cigarette smoking) who lives with someone that does not vape, or a non-vaper who lives with an exclusive vaper, then you may qualify for this study. The person who vapes/does not vape can be your roommate, partner etc. Potential participants will be screened prior to enrollment to ensure they are eligible. Once enrolled, participants will blow into a spirometer, which will measure their lung function and answer questions on respiratory symptoms. If you are interested, please email at rvlab1665@gmail.com or provide your details via this link: https://uab.co1.qualtrics.com/jfe/form/SV_6ExuSQMcdg3AC8K and we will contact you. Thank you!
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Recovering from a stroke? Still have problems with confusion, slow thinking, or memory? If so, you may eligible to take part in a study testing a new form of cognitive training designed to improve how quickly you process information and perform daily activities. The study pays participants $20 per training session on average. The training program, which requires several visits to UAB, can be tailored to fit your schedule. If you are interested, please call 205-934-9768 or email stacemc@uab.edu
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The UAB Youth Safety Lab is studying accidental injuries. We invite families with children ages 10, 11 or 12 who have experience with hunting or shooting to participate. The study involves 5 visits to the UAB Youth Safety Lab. Parents respond to questionnaires and children engage in a range of computer and laboratory tasks. Children will receive training in either firearms safety or nutrition and families will earn up to $550 for their participation, including $150 for each 2-hour visit and $50 for each 30-minute training session. Parking is provided. Children receive a small toy prize at each visit. There are no medical or stressful procedures involved and most children enjoy participating. Call the UAB Youth Safety Lab at 205-934-4068 to enroll or ask questions. You can also email us at ajohn@uab.edu
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You may be eligible to participate in a research study about the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $575 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.
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Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at, genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
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We are looking for male or female adults (18-65) who have had an amputation at least 6 months ago. This study is designed in two Phases to assess the needs of the local amputee population and to determine the potential of a diet to reduce pain and increase quality of life in amputees. In Phase 1, eligible participants will be asked to complete a small packet of questionnaires examining quality of life and diet. In Phase 2, eligible participants with pain for at least 6 months will complete a week of baseline diet and pain data collection before being placed on a 6-week low-carbohydrate diet. During the diet intervention, daily food will be provided and participants will return for testing at 3 and 6 weeks. Participants will receive up to $50 for completing Phase 1 and $150 for completing Phase 2 of the study. You may not be eligible to participate if you have significant health problems, or are taking certain medications. Please contact parade.study@gmail.com or call 205-234-1201. Leave a short message with your name, number, and mention that you are interested in the PARADE study.
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Are you a Female and Experience a Loss of Urine with Urge and Frequency? Do you have Overactive Bladder with Urinary Leakage? $200 Compensation will be provided. To find out if you are eligible, please call at 205-934-1777 or email Dr. Russell Stanley at russellstanley@uabmc.edu.
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The UAB Department of Dermatology is seeking people for a clinical study looking into ultraviolet light induced effects on the skin immune responses. This study may provide clues for the prevention of skin cancer. We are seeking 18-35 year old individuals, without a history of skin cancer, who are capable of being sunburned and who are not currently pregnant or planning to become pregnant the next 2 months. Participants may receive up to $500 in compensation. Please contact 205-801-8841 or UVstudy@uabmc.edu for more information.
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If you are age 50 -75 years, you may be eligible for a study to examine the effect of salt in the diet on blood pressure. Participation includes 4 in-person visits over 1-month; spaced 1-week apart, during which blood draws and blood pressure measurements will occur. If you qualify, you will eat your usual diet for 7 days, then study-provided meals that follow a low- salt diet for 7-days, and your own meals with extra salt in the form of study-provided bullion packets for 7 days, with a visit scheduled at the end of each. The day before these visits you will collect urine for 24 hours and wear a 24 hour blood pressure monitor. Study meals are provided at no cost to you, parking is provided, and additional compensation up to $350 is offered. Individuals with normal or treated and controlled high blood pressure, no food allergies, and who are not taking daily oral anti-inflammatory medicines (such as prednisone or ibuprofen) may be eligible for the study. For more information call 205-934-2024 or email kmhardy@uabmc.edu.
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You may be able to participate in this study if you: are 18 years of age or older, have been diagnosed with major depressive disorder, MDD, have not adequately responded to at least 1 different antidepressant treatment, and are currently on an antidepressant treatment. Please leave a voice message at (205) 975-0068 or email candacegreen@uabmc.edu for more information.
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Are you a caregiver? Do you know someone that is a caregiver? Would you like to earn $20? If so, the Caring for Adults with Difficulties Study (CFAD) needs you! This study examines stressors of caregivers to aging adults, their social support networks, caregiving demands, and personal experiences. To be eligible, you must care for a family member or friend at least 5 hours per week. You must also complete a 45 minute survey online or over the phone. Please contact ups by phone (205-975-9452) or email (mjfields@uab.edu). We look forward to your participation!
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If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians, and have no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail Nehal Vekariya at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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The Alabama Vaccine Research Clinic is conducting a COVID-19 Vaccine Research Trial Located at UAB’s 1917 Clinic at Dewberry on 5th Ave, the Alabama Vaccine Research Clinic is studying novel COVID-19 vaccines and how they can offer a broader range of protection against new variants. To qualify for this study you must be a generally healthy adult, 18 years or older, and have received a FULL series of COVID-19 Vaccination and a booster vaccination. Participation in this study will include 8-13 clinic visits. Study participants will receive COVID-19 variant vaccines. Compensation will be provided. If you are interested in participating in this study trial, or want more information on the Alabama Vaccine Research Clinic, please visit us at https://sites.uab.edu/avrc
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The ExCITES-PD clinical trial at UAB is investigating the effects of exercise on sleep and cognition through participation in a supervised exercise program. Assessments: cognitive tests, sleep study, brain MRI, and 3x/week supervised exercise training sessions for up to 6 months. Compensation provided. To learn more, contact Corina Catiul: ccatiul@uabmc.edu, 205-975-9556 or Jennifer Pilkington: jlpilkington@uabmc.edu, 205-934-8352.
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Do you have High Blood Pressure? Help us find out what is the right time to take blood pressure medication. You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure and have no history of heart problems or kidney problems. The study involves wearing a blood pressure monitor for 24-hours, 24-hour inpatient visits, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested.
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Healthy volunteers between the ages of 14 and 45 needed for research on psychosis spectrum disorders. Study procedures include: three MRI scan visits and two office visits over the course of 16 weeks, a clinical interview, memory, thinking, and concentration evaluations, and optional blood draws. Each of the five study visits will take approximately 3 hours. Compensation is up to $530. If interested please contact a member of our research staff at (205) 996-9813.
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Healthy volunteers between the ages of 19 and 45 needed for an MRI research study. Study procedures include a clinical interview, a one hour MRI scan, and a 30 minutes MRI scan. Compensation up to $110. If you are interested please call a member of our research staff at (205) 996-9813.
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Are you currently pregnant? If you are 14 to 39 years of age, less than 18 weeks pregnant, and planning to deliver at UAB, you may be eligible for our education based study. This study focuses on learning about healthy behaviors and how to make positive changes that could lead to a healthier pregnancy for both you and your baby. There are four study visits spread out over 13 weeks during pregnancy and one brief post-delivery visit where study staff visit participants in the post-partum unit. Participation includes a one-on-one education session, answering several questionnaires, and collecting lab work, including blood, mouth swabs & self-collected urine samples, and vaginal swabs. Also, three times during the study, participants are given a packet to collect two swabs at home and mail them in. Participants are compensated $230 for completing all study visits and specimens. For more information, please call Leslie Black at 205-919-5945, email PrPrepStudy@uabmc.edu, or text 408-214-0980.
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Researchers in the UAB School of Medicine are recruiting individuals 18 years and older who have drank alcohol in the past year. The study involves completing a brief online screening questionnaire to determine your eligibility. If you are eligible, you will complete a second set of questionnaires that lasts 90 minutes for which will receive $30. For more information about our study, please email us at trustlab@uabmc.edu
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We are seeking adult participants aged 60 and older. Participation includes a screening visit, cognitive testing, a fitness test, a sleep study, and a brain MRI. Time commitment: one week. PI: Amy Amara, MD, PhD, Associate Professor of Neurology Contact information: Jennifer Pilkington: jlpilkington@uabmc.edu; 205-934-8352 Corina Catiul: ccatiul@uabmc.edu; 205-975-9556
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Feel like you're missing out? If you are being treated for major depressive disorder (MDD) but still feel a lack or loss of interest in usually pleasurable activities, the TERPSIS Study, a clinical research study on an investigational medication for MDD, be of interest to you. The TERPSIS Study is researching a potential MDD therapy to improve symptoms of depression, and you may be eligible to participate. This study is now enrolling adults diagnosed with MDD Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no costs. Participants in the TERPSIS Study must: -Be 18 to 65 years of age -Have a clinical diagnosis of MDD -Be taking antidepressant medication(s) but still feeling a lack of interest in usually pleasurable activities -Fulfill other eligibility criteria For more information, please email kristinepike@uabmc.edu or call 205-975-8542.
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You may be eligible to participate in a research study: If you are a healthy female, between age of 18-50, still having a regular menstrual cycle & you are NOT on hormonal birth control (birth control pills or shots (i.e. Depo shot) or IUD, like Mirena). And, if you are willing to undergo an endometrial biopsy procedure. Participants will be compensated total of $200. Only requires 2 visits. For information, call us at 205-934-5498 or email Stephanie Clevenger at slangan@uabmc.edu.
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Do you have pain in one or both of your knees on most days? If so, you may qualify for a research study being conducted at the University of Alabama Birmingham. We are seeking people between 45 and 85 years of age to participate in a study of brain and breathing treatments for arthritis pain. The study involves seven visits over a three-week period to the study center at the University of Alabama Birmingham, where clinical tests and brain stimulation treatment will be done, along with brain scanning. Participants will receive $350 for completing the study. If you are interested, please call the PROACT Study at 205-934-9614.
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We are looking for individuals with prediabetes to participate in a 16-week weight loss program. Qualified participants will receive weekly group-based Zoom weight management classes with a health coach in addition to one-on-one nutrition counseling sessions on time-restricted eating or exercise counseling. Participants will also receive free lab work, fitness testing, body composition analysis, and weight/activity monitoring devices for the period of the study. To qualify for this study you should: 1) be aged 18-75, have BMI of 27, and 3) be willing to participate in weekly weight loss classes via Zoom and attend 3 in-person study visits at UAB Highlands Family and Community Medicine Clinic (60-90 minutes each). Compensation is $150. To get more information, please email Aseel El Zein at aelzein@uab.edu
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Researchers at University of Alabama-Birmingham seeking males and females ages 21 to 65 for study of alcohol’s effect on mood and attention. Earn between $20 and $200. Contact info: trustlab@uabmc.edu Phone: 205-975-7809
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CAN TAKING A CAPSULE BEFORE MEALS HELP YOU LOSE WEIGHT? WEIGHT LOSS RESEARCH STUDY For OVERWEIGHT MEN and WOMEN At UAB The purpose of the CAPSULE research study is to test weight loss effect of a hydrogel capsule, an orally taken pill that may create a continuing sense of fullness. Qualified participants will receive dietary and activity counseling sessions, as well as medical exams, lab work, and weight monitoring in the research clinic and by telehealth. This study requires a twenty-eight-week commitment. To qualify for this study, you should: • Be 18 years or older • Have a BMI between 27 – 40 • Not have any other significant illness or disease • Have had previous unsuccessful attempts to lose weight • Smartphone user Compensation of up to $525 is offered for the completion of this study. To have more detailed information sent to you, please call (205) 996-2689 or send email to Sarah Ehrlicher at sehrlich@uab.edu
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We are looking for individuals with spinal cord injury to participate in a home based exercise program for improving cardiometabolic health outcomes, such as body weight, blood sugar, cholesterol, and cardiovascular fitness. To qualify you must have a confirmed diagnosis of SCI at the cervical or thoracic level (C7-T12, classified as A, B, C, or D on the AIS scale), be at least 3 years post-injury, aged 19-65 years old. Participants will exercise for 16-weeks from home using an arm crank cycle ergometer and will receive $300 for completing the study. For more information, and to see if you might be eligible to join, please contact (205) 996-4114 or email at grdnfs@uab.edu

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Do you have Type 2 Diabetes? Are you 18 years or older? Not currently taking Insulin ? Are you currently being treated with stable doses of daily or weekly GLP-1 receptor agonist, the treatment can be with or without any of the following anti-diabetic drugs with stable doses: Metformin, Sulfonylureasa , Meglitinides (glinides), DPP-4 inhibitors, Sodium-glucose co-transporter 2 inhibitors, Alpha-glucosidase-inhibitors, Thiazolidinediones The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 52 week research study comparing the efficacy and safety of once weekly IcoSema and once weekly semaglutide, Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.

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This study is looking for individuals with spinal cord injury to participate in a home based exercise program for improving cardiometabolic health outcomes. Qualified participants must be at least 3 years post-injury, between the ages of 19-65, and must have a confirmed diagnosis of SCI at the cervical or thoracic level (C7-T12, classified as A, B, C, or D on the AIS scale). Participants will exercise for 16-weeks from home using an arm crank cycle ergometer. Participants will be compensated $300 for completing the study. For more information, and to see if you might be eligible to join, please contact 205-996-4114 or email at grdnfs@uab.edu.
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Do you have Type 2 Diabetes? Are you 18 years or older? Not currently taking Insulin? Are you currently being treated with stable doses of daily or weekly GLP-1 receptor agonist? This 52 week research study is seeking qualified participants to help compare the efficacy and safety of once weekly IcoSema and once weekly semaglutide. Qualified participants will receive study drug free of charge and may be compensated for time and travel. The treatment can be with or without any of the following anti-diabetic drugs with stable doses: Metformin, Sulfonylureasa , Meglitinides (glinides), DPP-4 inhibitors, Sodium-glucose co-transporter 2 inhibitors, Alpha-glucosidase-inhibitors, and Thiazolidinediones. For more information, and to see if you might be eligible to join, please contact 205-996-4015 or email at ccnrn@uab.edu.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians, and have no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail Nehal at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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DAY or NIGHT when is the right time to take blood pressure medication?? Help us to find out by joining our study. You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart problems or kidney problems. The study involves wearing a blood pressure monitor for 24-hours, 24-hour inpatient visits, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu if you are interested.
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Women 18 years and older who are currently experiencing any vaginal symptoms are invited to participate in a research study evaluation a new diagnostic test for bacterial vaginosis and vaginal yeast infection. Please call the UAB Sexual Health Research Clinic at 205-934-8166. Compensation will be provided.
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Minimum Eligibility Requirements: • You are 18- to 35-years-old. • You are currently wearing glasses/contact lenses. • You know how to use soft contact lenses. • You have had an eye exam within the last 2 years This study includes four to six visits, which will happen over ten weeks. If eligible, you will be compensated $20 to $40/visit with a maximum of $140 for your participation in the study. If interested, please contact Keyur Savla at 205-212-0355 or ksavla@uab.edu for additional information.

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Do you have Urinary Leakage? If you are eligible (women 65 years or older), you will take part in a 12-week hip muscle exercise program, individualized sessions taught by a licensed physical therapist specialized in hip strength. The program offers 12 private sessions, alternating in-person and phone visits (a “home program”) Compensation will be provided. For more information, please call 205.934.5498.

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A clinical research study is now enrolling eligible adults. The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an investigational medication when it is used alone in people with TRD. You may be eligible to participate if you: • Are 18 years of age or older • Have been diagnosed with TRD • Have not adequately responded to at least 2 different antidepressant treatments If you are interested, additional eligibility criteria will be assessed by the study doctor or staff. The commitment for the study is about 24 weeks. Qualified patients may receive investigational study medication and some study-required medical care at no cost. For more information about this study, you may visit www.clinicaltrials.gov and search “54135419TRD4005” or contact Kristine at 205-975-8542 or kristinepike@uabmc.edu.

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A clinical research study is now enrolling eligible adults between the ages of 18-74 years of age. The purpose of the study is to evaluate the safety and effectiveness of an investigational medicine in people who have depression with sleep problems. Must have been diagnosed with depression, Have taken antidepressants in the past that did not work well for you and currently taking an antidepressant medication but still having symptoms of depression. Having difficulty falling asleep, or or do not feel rested the next day. If you are interested additional eligibility criterial will be assessed by the study doctor or staff. Qualified patients may receive study-related medical care and investigational study medication at no cost. In addition, reimbursement for study-related travel may be provided. Please contact Dana Green 205 975-6426

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Participants must be: • Ages 21 to 65 • Able to safely consume alcohol • In good physical and mental health Participant activities: Attend an initial 1-hour study appointment, and a second appointment lasting 1-11.5 hours. Incentives: $20 for Session 1. For Session 2, earn $20 per hour, between $20 and $200. Alcohol and Mood Study: 205-975-7809
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If you are between the ages of 18 -75 yrs and have a body mass index between 19 - 45 kg/m2 you may be eligible to participate in a study exploring how much oxalate (a normal product of the body, also found in food) is made by the body and eliminated in urine. Participation involves eating study-provided meals for 5 days, providing urine and blood samples, one imaging visit (DXA) and one day-long visit during which an intravenous infusion of oxalate is given. Study meals are provided free of charge and additional compensation up to $375 is offered. Individuals with obesity, overweight or normal weight, and with and without a history of kidney stones are all welcome to the study. For more information call 205-934-5712 or email kidneystone@uabmc.edu.
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We are recruiting 9th grade Black males for a new study that is focusing on film viewing and academic functioning. The project involves viewing 4 films and completing 3 surveys with the ability to make up to $70 dollars for participating. This study is designed to take place completely from the participant’s home. If you are interested in learning more email afis.uab@gmail.com or call/text at (205) 549-3416 for more information. 
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You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, wearing a blood pressure monitor for 24-hours, a 24-hour inpatient stay, and collecting blood and urine samples. The meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu if you are interested.

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If you are between the ages of 18 -75 yrs and have a body mass index > 30 kg/m2 you may be eligible to participate in a study exploring the reason why individuals who have high BMI have an increased risk of forming calcium oxalate kidney stones. Participation involves eating study-provided meals for 4 days, providing urine and blood samples. Study meals are provided free of charge and additional compensation up to $140 is offered. For more information call 205-934-5712 or email kidneystone@uabmc.edu.

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If you are between the ages of 18 -75 yrs and have type 2 diabetes you may be eligible to participate in a study exploring the reason why individuals who have diabetes have an increased risk of forming calcium oxalate kidney stones. Individuals with obesity, overweight or normal weight are all welcome to the study. Participation involves eating study-provided meals for 4 days, providing urine and blood samples. Study meals are provided free of charge and additional compensation up to $140 is offered. For more information call 205-934-5712 or email kidneystone@uabmc.edu.

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Do you experience urine leakage with a strong and sudden urge and you leak before reaching the toilet? You may be eligible to participate in this important study if you are female and 21 years of age or older, if you are experiencing urine leakage with the feeling of urgency, coughing, sneezing, or laughing. For more information, contact our research team at 205-934-5498. Compensation is provided.

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Do you experience accidental bowel leakage? You may qualify for a bowel leakage research study if you are female, 18 years or older, and have had accidental bowel leakage for at least 6 months. For more information contact 205-934-5498. Compensation is provided.

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You may be eligible to participate in the UAB’s Cardiovascular Research Biobank (CARBON), a repository of biological samples that will be used for future research about heart disease, diabetes, genomics, and more. Participants must be over the age of 18. The study will require one brief visit to UAB and collection of blood samples. Participants will be compensated. Please contact Nehal Vekariya at carbonstudy@uabmc.edu or 205-934-7173 if you are interested.

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Healthy Volunteers Needed If you are: • 18-50 years of age • Can read and write in English • Are generally healthy • And have no history of mental illness or psychiatric disorders

For more information and to determine eligibility, please call UAB Office of Psychiatric Research at (205) 934-8203. **Compensation is provided**

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The UAB Epilepsy Center is looking for participants aged 15 and older for a brain imaging study. Eligible individuals will have psychogenic non-epileptic seizures (PNES) without co-morbid epilepsy. The study involves one visit at UAB Highlands Hospital and will last up to 2.5 hours. Participants will undergo a brain MRI, complete questionnaires, and provide a small amount of blood. You will be compensated $100 for completing the visit. If interested, please contact Dr. Christina Mueller at (205) 671-4355 or cm1@uab.edu.

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Are you interested in managing your weight? Men and women age 19-75 whose body mass index (BMI) range from 30-50 are needed for SWOP, a two-year study investigating the effects of daily self-weighing. Some participants will be asked to weigh themselves daily for two years using the study-provided scale that will pair with the participant's own smartphone. All participants will be asked to complete brief visits at UAB every 6 months (a total of five visits). Compensation provided. Participants must be under the care of a primary care doctor, have steady Wi-Fi at home, and live within 50 miles of UAB campus. Call 205-996-SWOP or email SWOP@uabmc.edu to find out if you qualify.
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Do you have pain in one or both of your knees on most days? If so, you may qualify for a research study being conducted at the University of Alabama Birmingham. We are seeking people between 45 and 85 years of age to participate in a study of brain and breathing treatments for arthritis pain. The study involves seven visits over a three-week period to the study center at the University of Alabama Birmingham, where clinical tests and brain stimulation treatment will be done, along with brain scanning. Participants will receive $350 for completing the study. If you are interested, please call the PROACT Study at 205-934-9614.

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Are you a Female and Experience a Loss of Urine with Urge and Frequency? Do you have Overactive Bladder with Urinary Leakage? Compensation will be provided. To find out if you are eligible, please call at 205-934-1777 or email Dr. Russell Stanley at russellstanley@uabmc.edu.

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Are you struggling with Opioid addiction? If so, you may be eligible to participate in a research study at UAB that focuses on biomarkers in people with opioid addiction. The study includes 1 visit and takes up to 2 hours to complete. For more information, please call the UAB Office of Psychiatric Research at (205) 934-8336. You will be compensated $20 for your time and efforts.
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Healthy women needed for a research study. You may be eligible to participate in a research study: If you are female between age of 18-45, If you a healthy and still having a regular menstrual cycle, And, if you are willing to undergo an endometrial biopsy procedure. Participants will be compensated total of $200. Only requires 2 visits. For information, call us at 205-934-5498 or email Stephanie Clevenger at slangan@uabmc.edu.
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 Are you 18 years old or older? Have you drank alcohol in the past year? Researchers in the UAB School of Medicine are recruiting individuals 18 years and older who have drank alcohol in the past year. The study involves completing a brief online screening questionnaire to determine your eligibility. If you are eligible, you will complete a second set of questionnaires that lasts 90 minutes for which will receive $30. For more information about our study, call our research staff at 205-934-2851 or email us at arshnoorgrewal@uabmc.edu.
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You may be eligible to take part in this study if you have previously had a heart attack (myocardial infarction) or brain attack (stroke) or have been diagnosed with poor circulation. If you have reduced kidney function or if you have inflammation in your blood vessels ? The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a 4 year research study to look if an investigational medicine ,called ‘ziltivekimab’ can be used to treat people with cardiovascular disease, chronic kidney disease and inflammation. Qualified participants will receive study drug at no cost and may be compensated for time and travel. For more information, and to see if you might be eligible to join, contact (205) 996-4015 or email at ccnrn@uab.edu.
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Are you 18 or older and currently in treatment for alcohol or substance use disorder? Researchers in the UAB School of Medicine are recruiting individuals 18 years and older who have drank alcohol in the past year. The study involves completing two surveys online, one screening and one questionnaire, which will take 90 minutes to complete. Each participant will receive $30 for completing all the surveys. For more information about our study, call the research staff at 205-934-2851.
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You may be eligible to participate in a research study about the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated. To participate, please contact Nehal at 205-934-7173 or email us at nauticalstudy@uabmc.edu.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians, and have no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Nehal Vekariya at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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The Neuroinflammation, Pain, and Fatigue Lab is looking for women with relapsing-remitting Multiple Sclerosis ages 18-65 for a brain imaging study. The study includes a phone interview and two visits to UAB hospital: one screening visit including blood draws, and one imaging visit, during which we will acquire Positron Emission Tomography (PET) and Magnetic Resonance Images (MRI) of your brain for one hour. PET imaging involves exposure to a small amount of radiation. There will also be questionnaires. You will be paid $400 for completing the study. The purpose of the study is to investigate whether patients with multiple sclerosis have increased brain inflammation compared to healthy people. If interested, please contact Chloe Jones at chloej@uab.edu or 205-434-1502, and leave your name and phone number.
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Clinical trial evaluating a novel, non-invasive radiation treatment for ventricular tachycardia refractory to medication and catheter ablation The UAB Departments of Radiation Oncology and Cardiology are looking for patients with ventricular tachycardia (VT) not controlled by medications and catheter ablation. The trial will allow patients suffering from VT despite standard of care regimens to undergo non-invasive cardiac radioablation (CRA; a type of stereotactic body radiotherapy) to the area of the heart responsible for their symptoms. Stereotactic body radiotherapy is delivered with a device called the linear accelerator, which is primarily used to treat patients with cancer. UAB is one of the first centers in the U.S. to obtain a Food and Drug Administration (FDA) investigational device exemption for use of the linear accelerator in this capacity on a phase I/II trial. The study is being conducted in collaboration with the Washington University School of Medicine in St. Louis, a center which pioneered this promising technique in the U.S. For more information on the RAD 1901 trial, please contact Adelyn Gillon, clinical research coordinator, at 205.975.3019 or agillon@uabmc.edu" contenteditable="false">agillon@uabmc.edu.
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November 23, 2021

Asthma clinical trial

If you have asthma, are at least 18 years of age, in the Los Angeles Region, (California) haven’t had oral steroids in at least 4 weeks, and are willing to donate 30 mL of blood, equivalent to two tablespoons, please contact Racheal Ogbebor at email Rachealogbebor@gmail.com.
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Rural Research Participants Needed FSU College of Nursing invites individuals with heart failure and their care partners who live in rural areas to participate in a research project under the direction of Lucinda J. Graven, Ph.D., APRN. Care teams will partner with a registered nurse to manage daily challenges related to heart failure self-care by telephone. Compensation up to $200 per care team who complete the telehealth program. Please contact Joan Grant Keltner, Ph.D., RN at (205) 934-6527 or grantj@uab.edu. For more information, you may also use: https://fsu.qualtrics.com/jfe/form/SV_3IPqQs7MAPmuHpH
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The purpose of the study is to understand the experience of living with COPD and HIV. Only 1 visit with 1 hour interview is required. To qualify, participants must be 50 years of age or older and diagnosed with COPD and HIV for at least 1 year. Eligible volunteers will be compensated $50 for a visit. For more information and to check your eligibility to join, please contact (205) 934-5482 or e-mail junbyun@uab.edu
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The Neuroinflammation, Pain and Fatigue Lab at UAB is looking for women with Fibromyalgia. Participants will come to UAB for a 2-hour screening visit and a 9-hour (all-day) study session. During the study session, we will induce a temporary immune response and assess its effect on fibromyalgia symptoms, including pain and markers of immune activity. You will provide blood samples and undergo brain imaging before and after the immune activation procedure. You will be paid $650 for completing both visits. Participants must be: currently suffering from moderate to severe Fibromyalgia, or be a healthy female and ages 18-55, not pregnant or planning to become pregnant, without significant other medical conditions such as heart disease, not using any opioid medication, for example, Norco, Tramadol, Percocet. To participate, contact Indonesia at 205-289-8748 or e-mail ijordan@uab.edu.
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Participants between the ages of 65-89, and individuals diagnosed with Parkinson’s disease between the ages of 45-89 are needed for a research study on walking. This study is being done to assess how well individuals can modify walking patterns. If you qualify, we anticipate that your participation in the study will span a single study visit, with a total time commitment of 3 hours. You will be compensated for your time. Contact Christopher Hurt at cphurt@uab.edu or  at 205-934-8517, if you are interested.
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Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.

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We are enrolling opioid users without a history of psychosis, endocrine diseases, inflammatory diseases, or autoimmune diseases. If you meet these criteria you may be eligible to participate in a research study. Compensation provided up to $20. For more information, please call the UAB Office of Psychiatric Research at 205-934-8336.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians and have no history of diabetes, heart problems, or kidney problems. The study involves performing exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Nehal Vekariya at nvekariya@uabmc.edu if you are interested.
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You may be eligible to participate in a research study about the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated. Please e-mail Nehal Vekariya at nvekariya@uabmc.edu if you are interested.
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The Neuroinflammation, Pain and Fatigue Lab at UAB is looking for women with Fibromyalgia, and women who are healthy and without pain. Participants will come to UAB for a 2-hour screening visit and a 9-hour (all-day) study session. During the study session, we will induce a temporary immune response and assess its effect on fibromyalgia symptoms, including pain and markers of immune activity. You will provide blood samples and undergo brain imaging before and after the immune activation procedure. You will be paid $650 for completing both visits. Participants must be: currently suffering from moderate to severe Fibromyalgia, or be a healthy female and ages 18-55, not pregnant or planning to become pregnant, without significant other medical conditions such as heart disease, not using any opioid medication, for example, Norco, Tramadol, Percocet. To participate, please contact Indonesia at 205-289-8748 or e-mail ijordan@uab.edu.
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UAB's Urogynecology and Pelvic Reconstructive Surgery is conducting a 3 month at-home non-invasive lower leg stimulation study. You may be eligible if you are female and 18 years of age and older, have a history of chronic Bowel Leakage for at least 6 months, and have tried at least 2 treatments, including medications, diet, and pelvic exercises. Compensation will be provided. If you would like more information about the study, please contact 205-934-5498.
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Are you taking Metformin alone or metformin with a sodium-glucose transport protein 2 (SGLT2) inhibitor to treat your diabetes? The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a 39-week research study to see how two new study medicines work together on blood sugar levels in people with Type 2 diabetes. Qualified participants will receive study-drug free of charge and may be compensated for time and travel. For more information, and to check your eligibility to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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You could be eligible to participate if you are 18 or older and a premenopausal female. Also, If you have been diagnosed with endometriosis, and are experiencing pain associated with endometriosis. There is no cost for your participation. For more information, contact our research team at 205-934-1322. Compensation is available for those who qualify.
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The purpose of the study is to measure maximum walking speed and step length with virtual reality and customizable exercise games as feedback sources on a robotic treadmill. The targeted population is individuals with hemiparesis, in a chronic and stable stroke stage, who are able to follow instructions, and able to walk independently for at least three minutes. Based on a phone screening, eligible participants will attend up to two separate sessions at UAB Spain Rehabilitation Center. In each session, they will go into different walking or stepping performance conditions. The session will last about two hours, and participants will be paid 30$ per session for their time and effort. For more information please call Saleh Alhirsan at (205) 261-3853 or by email atalhirsan@uab.edu.
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We are looking for adults between 21-55 years old and diagnosed with Attention Deficit and Hyperactivity Disorder (ADHD), and use stimulant medication to participate in our study. We want to determine the role of ADHD stimulant medication on balance and other factors, such as physical activity in improving balance performance. We hypothesize that ADHD will improve balance performance in adults with ADHD. We also hypothesize that moderate to vigorous physical activity behaviors will positively influence balance performance in this population. Participants will be required to make two visits. Once on-medication; and on the second visit, we will ask participants to forgo ADHD medication 24 hours before the testing. For more information please contact Mansour at (205) 503-2977, or by email at amansour@uab.edu.
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The purpose of the SCIPE study is to examine two 8-week remotely delivered exercise interventions: Movement-to-Music, and Standard Exercise Training. Enrolled participants will be randomized into one of three groups: M2M, SET, or attention control. The primary goal of this study is to examine changes in physical activity levels after the 8-week M2M and SET interventions. We hypothesize that M2M and SET participants will have significant increases in physical activity, sleep quality, quality of life, and decreases in pain compared to the Attention Control group after the 8-week intervention. The secondary aim is to examine the effects of the M2M and SET interventions on health and quality of life outcomes. Exercise enjoyment in M2M and SET participants will also be explored. The tertiary aim is to evaluate the demographic, clinical, and psychosocial variables of two participant groups: 1) compliant participants who completed ≥ 50% of the intervention, and 2) non-compliant participants who completed post-testing but only 50% of the intervention, or did not complete post-testing. The SCIPE study will take place entirely online. The exercise program will be delivered to you in a video format, so you can exercise anywhere that is convenient for you. For more information please contact (205) 209-2245 or email scipe@uab.edu.
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You may be eligible to participate in this important study if you are premenopausal female age 18-49, if you have been diagnosed with endometriosis, and are experiencing moderate to severe pain associated with your endometriosis. There is no cost for your participation. For more information, contact our research team at 205-934-1322. Compensation is available for those who qualify. https://endometriosis-study.com/
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If you are 18 years of age or older and currently taking the blood thinners Xarelto (rivaroxaban) or Eliquis (apixaban), you may be eligible to participate in a research study. This study is being done to determine how your kidney function affects how you metabolize Xarelto or Eliquis. The study involves keeping a medication log for one week and one (12 hour) visit to UAB where we will collect blood samples at different times during the day. Participants will be compensated $150 for completing the one-day study visit. If you are interested or for more information, please contact our research team at pkpdstudy@uabmc.eduor 205-917-9800.
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You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking sacubitril/valsartan or valsartan, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Vibhu Parcha, vparcha@uabmc.edu if you are interested. 
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You may be eligible to participate in a research study about the effects of exercise and Metoprolol, a blood pressure pill, on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasian with no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please email Dr. Vibhu Parcha at vparcha@uabmc.edu if you are interested.
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If you are 18 years of age or older, have tried at least 1 antidepressant medication, are feeling sad, down, hopeless, guilty, tense, or irritable, and are in good physical health, you may be eligible to participate in a research study comparing medications with transcranial magnetic stimulation. You will receive compensation for your time. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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The RECOVER study will investigate the use of Vagus Nerve Stimulation (VNS) Therapy in up to 1,000 people across the United States. To join the RECOVER study you must be 18 years or older and: currently depressed, have depression (or bipolar depression) that has lasted for at least two years or recurred several times, and have tried at least four types of antidepressant treatments and not found them helpful. Please leave a voice message at (205) 975-0068 or email candacegreen@uabmc.edu for more information.

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If you are at least 18 years of age, can read and write in English, are generally healthy, and have no history of mental illness or psychiatric disorders, please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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You may be able to participate in this study if you: are 18 years of age or older, have been diagnosed with major depressive disorder, MDD, and have not adequately responded to at least 2 different antidepressant treatments. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have Major Depressive Disorder (MDD) that hasn’t responded to anti-depressant medication, learn about this research study of an investigational drug for MDD. As part of their study participation, patients will be regularly evaluated and closely monitored by a team of medical professionals. To pre-qualify for this study, you must: be 18 to 65 years of age; have been diagnosed with MDD; be in a current depressive episode for at least 8 weeks but not more than 12 months; and have been taking an antidepressant medication for at least the last 8 weeks. Additional criteria will apply. All study-related visits, tests, and study drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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This is a paid research opportunity for adults who provide care for adult loved ones 45 years or older. We are actively recruiting for a research study to examine caregivers’ experiences and health outcomes. To be eligible, caregiver participants need to commit to providing care for their loved ones at least five hours weekly, and their loved ones need to be ages 45 and older. The study takes approximately 45 minutes to complete and can be completed via our online survey or over the phone with one of our trained research assistants. Participants will receive a $20 gift card for completing the study. The link to complete the study is: https://uab.co1.qualtrics.com/jfe/form/SV_bmAfy0dohaFEciG. For more information, please call and leave a voicemail for our research lab at (205) 975-9452, or email Wesley Browning at wbro9119@uab.edu, or Celine Atkins at gcat347@uab.edu.
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Is your child ages 4 or 5? If so, they may be eligible to participate in a study at the UAB Youth Safety Lab. This study is about superheroes and children’s play. It involves a 90-minute visit to our laboratory and involves no risk or invasive behaviors. During the visit, you complete questionnaires while your child participates in games with a research assistant. Your child will also be randomly assigned to dress up as either a superhero or a student in school. You and your child earn $40 and take home a special prize as a thank you for your time. For more information, and to see if you might be eligible to join, please contact (205) 934-4068 or email chmorgan@uab.edu.
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The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a research study to evaluate the effectiveness of an investigational drug to treat people with Type 2 Diabetes and obesity. To qualify, you must have Type 2 Diabetes, older than 18 years old, moderately overweight, diet-controlled or taking oral diabetes medications. Qualified participants will receive the study drug free of charge and compensation for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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Looking for individuals between the ages of 18-70 with a diagnosis of traumatic brain injury, spinal cord injury, spina bifida, cerebral palsy, stroke, Parkinson disease, or multiple sclerosis to participate in Movement-to-Music (M2M), a rhythmic-based exercise program provided entirely remotely from Lakeshore Foundation. You may be eligible if you have stable cardiovascular conditions and have not participated in a similar research study in the past 6 months. All equipment for completing the program and additional compensation provided. To learn more about this opportunity and if you are eligible, please call Lori Theriot at (205) 313-7455 or email m2mstudy@uab.edu.
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We are looking for adults with type 2 diabetes for a research study to see if eating large amounts of whole fruit can improve your blood sugar and reduce your need for diabetes medications. You may be eligible if you are 20-65 years old, overweight (BMI 27-45), diagnosed with type 2 diabetes within the last 6 years, and are not taking insulin. Participants will be provided with meals for 12 weeks, a high-speed Vita-Mix blender, and $1,375 for completing the study. Since this study is time-intensive, we are seeking only highly motivated and dedicated participants. If you are interested, please complete the brief electronic form at http://bit.ly/fruit_study. For more information, please contact Cody Hanick at chanick@uab.edu or (262) 923-0672.
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We are looking for adults with type 2 diabetes for an exciting research study to see whether intermittent fasting and/or using light therapy can improve your blood sugar, improve your overall health, and reset your body clock. Participants will either eat early in the day, graze throughout the day, and/or use a special light therapy box or glasses. You may be eligible if you have type 2 diabetes, are 30-80 years old, are not taking insulin, and usually wake up between 5:00 and 9:00 am. The main part of the study lasts 16 weeks and involves two overnight tests in our clinic (which can be done on weekends, if preferred). Participants will receive $2400 for completing the study. 

If you are interested, please follow the link http://bit.ly/clocksstudy  to apply for the CLOCKS study. Or for more information, please contact our research team for more information: Errin Jessie or Kimberly Armstead at CLOCKSSTUDY@uab.edu or 205-975-3944 or 205-934-6202.

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