Clinical Trials
Did you recently have a baby and want help losing weight?
Do you sometimes feel hopeless, or that life has no purpose?
To see if you qualify call 205-379-7527.
Do you identify as a trans man or woman? Are you 18-85 years of age? Do you have low back pain? Would you like to take part in a research study?
If the answer to all of these questions is YES, you could be eligible to participate in a research study examining the impact of gender identity, hormone levels and sex assigned at birth to pain sensitivity in people who have chronic low back pain. – the ERASED study (Racial and Socioeconomic Differences in Chronic Low Back Pain).
The commitment to this study is two visits that will last approximately 4-5 hours and include:
- One (1) telephone screen
- Two (2) visits to UAB where you will fill out questionnaires, have a single blood draw, take part in pain sensitivity and functional testing.
If you are eligible to participate in this study, you will receive up to $400.
- Identify as transgender
- Be between 18 and 85 years of age
- Have none of the following health conditions (HIV+, cardiovascular disease, uncontrolled hypertension)
Participants can be on HRT (hormone replacement therapy) or not.
To find out more about this study, call 205-934-8743. For information regarding research studies and rights of participants, call 205-834-3625.
There are no approved treatments specifically for cocaine use disorder. We are looking for adults (18-65 years of age) who are using cocaine and who are interested in reducing or stopping their use. The purpose of our study is to test a combination of two medications for 2 months as a possible treatment for cocaine use disorder.
This study includes the use of a placebo, which looks like the medication we are testing but does not include any active medicine. Study medication and assessments will be provided to participants at no cost. Participants will receive compensation for their time and efforts.
Study information will be kept strictly confidential. Your privacy is important to us.
Call us for more information at 205-996-0211 or email us at curb2study@uabmc.edu
Do you have a child aged 6 months to 18 years of age that is scheduled to receive the COVID-19 vaccine series or booster?
CMVibe Study: Evaluates a CMV vaccine in healthy females or males aged 9-15 years old and healthy females aged 16-25 years old.
Help us find out by joining our study at UAB by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.
DON’T let urine leakage stress you out
Call us today at (205) 934-5498 to join our urogynecology clinical trial and find the perfect treatment plan tailored to you.
To participate in this research, you must:
- be 11 to 18 years old
- have no diagnosed medical conditions
- have a parent/guardian available to participate in lab visits
If you choose to participate in the study, you will be part of the healthy control group. You will come for 2 lab visits 13 weeks apart. The adolescent can be compensated up to $100 total. To find out more about the study, call 205-975-4205 or email pedshealthlab@uabmc.edu.
This study is a 5-hour workshop delivered in groups that is based on principles of acceptance and commitment therapy (ACT). Participants will learn new skills to facilitate the adoption of healthy lifestyle behaviors, such as eating a healthy diet and exercising regularly. These skills include identifying values, tolerating the discomfort associated with lifestyle change, identifying self-sabotaging thoughts, and more!
For more information, please contact Andrea at andrealdavis@uabmc.edu or 205-206-9434.
LGBTQ+ Cancer Well-Being Study
Hispanic Dementia Caregiver Well-Being Study
To be contacted by the research team register here: https://uab.co1.qualtrics.com/jfe/form/SV_d3TmeAlFEPBRmNU
¿Cuidas de un familiar con problemas de memoria o demencia/enfermedad de Alzheimer?
La Universidad de Alabama en Birmingham (UAB) está invitando a cuidadores familiares hispanos y latinos para que completen breves encuestas para nuestro proyecto. Tus respuestas ayudarán a comprender mejor las experiencias del día a día y a desarrollar servicios para apoyar mejor a los cuidadores familiares de la comunidad. Les compensaremos por su participación. Sus respuestas permanecerán anónimas. Para saber más escribe a starlab@uab.edu o llama por teléfono al 205-996-0339 y pregunta por Lorelí Alvarez.
Para ser contactado por el equipo de investigación haga click aquí: https://uab.co1.qualtrics.com/jfe/form/SV_d3TmeAlFEPBRmNU
Do you vape or live with someone who vapes? You may be eligible to participate in this PAID vaping and lung function study.
Are you pregnant and wanting to eat healthier?
Transgender Men and Non-Binary People Needed
1. Accidental bowel leakage (fecal incontinence)
2. Urinary leakage (urinary incontinence)
Please call 205-934-5498 to learn more about these studies.
This study focuses on better understanding breast milk composition, the presence or absence of CMV in breast milk, and its possible transmission to babies. CMV is a common virus that most people in the US are infected with by adulthood. Participants will meet with study staff once a month for six months to collect non-invasive samples and answer a questionnaire. Samples collected include oral swabs from you and your baby, a small quantity of breast milk and a skin swab from you, as well as a urine and stool sample from your baby. Participants will be compensated up to $300 for completing the study visits and providing samples. Eligible participants may also qualify for additional sub-studies for additional compensation up to $800.
For more information, please contact us via phone or email at:
Phone: 205-975-3752
Email: milk@uabmc.edu
BrainREAD: A Reading Intervention Study for Children
SAVITRI Study for Depression
Alzheimer’s Dementia and Agitation Clinical Study
This study seeks to examine socio-emotional constructs, such as motivation, resilience, and stigma using an assessment survey. The project’s final goal is to provide educators and parents with targeted socio-emotional intervention techniques for a more holistic perspective on student learning.
All English-speaking children from 11 to 14 years of age are eligible. Students with Specific Learning Disabilities are encouraged to participate.
Click here to learn more: https://drive.google.com/file/d/1JCw1f7PfRTRHJhdlV39ZHH_g3nThBwBq/view?usp=sharing
Estradiol and Complement Activity Trial
The Alabama Vaccine Research Clinic at UAB are seeking volunteers for a phase 1 HIV prevention study. This study is to evaluate the safety and immunogenicity of synthetic DNAs encoding in adults without HIV. This trial is in search of healthy HIV negative adults between the ages of 18-55. Procedures will include blood draws and injections of study vaccine, as well as the collection of white blood cells. White blood cells will be collected by a procedure called leukapheresis. Participants will be compensated for their efforts in this study.
If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
Trans Men
Vitamin C and Kidney stones study
If you are 18 or older with a history of calcium oxalate kidney stones, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
For more information email kidneystone@uabmc.edu
Vitamin C and Kidney stones study
If you are 18 or older and in good health, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.
For more information email kidneystone@uabmc.edu
See the website at www. preventabletrial.org
Please call or text: (205) 224-2567 or email destinytaylor@uabmc.edu if you are interested.
Gonorrhea Prevention Vaccine Study
Phone number A- 205-934-8166 - Sexual Health Research Clinic.
• Five (5) visits to UAB where you will fill out questionnaires, complete a DEXA scan, blood draw or Quantitative Sensory testing. These visits will last anywhere from 1-3 hrs.
• 6 weeks on a randomized diet, we will provide three (3) meals and two to three (2-3) snacks per day.
Participants must:
• Be currently suffering from pain related to osteo knee arthritis
• Be free from other serious health conditions (diabetes, cardiovascular disease, eating disorders, metabolic disease)
Participants will receive up to $250 for completing the study and meals will be provided. Please contact DIRECT at DIRECTPAIN1@gmail.com (205) 834-3628. Leave a short message with your name and number.
DECLARE Study
The purpose of this research study is to examine the effects of 10 weeks of exercise on the brain. DEcreasing Cognitive Loss and Vascular Rarefaction with Exercise (DECLARE) is focused on the elucidation of exercise effects on brain health and the way by which exercise mitigates age-related growth factor deficiencies, hypertension and cognitive decline.
To participate in this research, you must:
– have high blood pressure
– be between 55-75 years of age
– be healthy (Ok to be on medication)
– not currently exercising
Please contact us at 205-996-5592 or use the following link to complete the 5 minute screening questionnaire: https://uab.co1.qualtrics.com/jfe/form/SV_6FigP3lOJYdvl9c
adolescent study for depression
Are you felling sad, down, or hopeless?
Are you feeling guilty, tense, or irritable?
If so, you may be eligible to participate in a study.
Compensation provided.
For more information, please call Brennan wink at 205-975-4208 or send an
email to Brennanwink@uabmc.edu
Lung Health Cohort
Are you or someone you care about age 25-35 and interested in lung health? Join the landmark Lung Health Cohort Research Study to improve the health of future generations.
The pioneering NIH-funded study will follow 4,000 young, healthy adults to paint a clearer picture of lung health and the factors involved in predicting and preventing lung disease.
To learn more, visit: Lung.org/lung-study
Family caregivers of people with dementia are invited to participate in the coach-guided videoconferencing acceptance and commitment therapy study
Application of a Reimbursable Form of Constraint- Induced Movement Therapy for Upper extremity Recovery Following Stroke: A Pilot Study
The role of S-cone neural activity in eye growth regulation and refractive development
This study has been approved by the University of Alabama at Birmingham Institutional Review Board (ref: 300008644).
You will be eligible to participate in the study if you are:
-18-35 years old.
-You have corrected to normal vision (with glasses and contact lenses)
-You have good general and ocular health
This study includes a single visit that is expected to last 90 minutes or less. If eligible, you will be compensated $50.00 for your time and participation in the study.
Dr. Safal Khanal
Principal Investigator
Department of Optometry and Vision Science
University of Alabama at Birmingham
If you need more information or would like to participate in the study, please contact:
Dr. Safal Khanal
skhanal@uab.edu
(205) 934 4558
Healthy Women Needed for a Research Study
BabyCOVE Study: Evaluates the COVID-19 vaccine in healthy infants aged 12 weeks to less than 6 months old.
We are doing this study to see if CagriSema (Cagrilintide/semaglutide), a new medicine intended for the treatment of obesity, is safe for use in people living with obesity and cardiovascular disease. The study will also include some people with type 2 diabetes and/or chronic kidney disease.
You may qualify to participate if::
- You have had a stroke, a heart attack (myocardial infarction), or have poor circulation (peripheral
- arterial disease)
- You are 55 years of age or older
- You are living with obesity (BMI ≥ 30 kg/m2 )
- You can have type 2 diabetes and/or chronic kidney disease
- You are able to attend regular clinic visits and receive phone calls over
- a period of 3 years
Want to know more about the REDEFINE 3 study?
Call the study team at (205) 996-4015 or via email ccnrn@uab.edu
SAVITRI Study for Depression
Alzheimer’s Dementia and Agitation Clinical Study
Are you struggling to find a treatment for depression that works?
People who participate in RECOVER will receive VNS Therapy and all study-related care at no cost to them.
To join the RECOVER study, you must be 18 years or
older and:
1. Currently depressed
2. Have depression, or bipolar depression, that has lasted for at least two years or recurred several times
3. Have tried at least four types of antidepressant treatments and not found them helpful
4. Have Medicare Insurance
Seeking Gulf War Veterans for Brain Imaging Study
Healthy African American Men between the ages of 18 and 40 are needed for the Exercise and Beta-Blocker Study
Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
Are you a healthy African American between the ages of 18 and 60?
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.
Do you have Type 2 Diabetes and overweight
The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 78 week research study to look into how well semaglutide once weekly medicine works in participants with obesity and type 2 diabetes
Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
Tivanisiran for Dry Eye in Subjects with Sjögren’s Syndrome
You may be eligible to take part in the SYL1001_V Study if:
• You are 18 years or older
• You have a diagnosis of Sjögren’s
• Other entry criteria apply and your eligibility will be determined by
the study staff
If you decide to take part in the study, your participation could last approximately 3.5 months and consist of 5 to 6 visits to the study center. You will be reimbursed for each completed visit.
If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
Eligible enrolled participants will receive:
- Supervised exercise training at no cost
- Blood pressure medication at no cost
- Convenient parking at no cost
- Compensation for time
If you are interested, please call 205-996-3005 and mention The ACES Study or apply here -https://www.uab.edu/medicine/exercise/volunteer-clinical-trials/aces-trial.
Do you have Type 2 Diabetes? Tired of out-of-control blood sugar?
For more information, please contact us at: 205-224-2567, or freedom@uabmc.edu, or fill out this pre-screening form and we will get in touch with you: https://redcap.link/freedom
This study will last up to four years and will involve doing in-person visits every 6 months and filling out an online questionnaire from home every 3 months. At the first study visit you will be asked a series of questions or fill out a questionnaire about who you are (such as age, sex, or race), medical conditions that may affect the chances of having long-term effects of COVID-19, whether you have been vaccinated against COVID-19, and any symptoms you currently have. You will have a brief medical exam and we will also collect samples of your blood, saliva, stool, nasal swab and urine. Some participants will be invited for additional medical examinations and tests. You will be compensated.
Adult Volunteers with history of Chronic Obstructive Pulmonary Disease (COPD) needed for study
Can Intermittent Fasting or Calorie Restriction Slow the Aging Process? Healthy Volunteers Needed!
Help us find out by joining our study. The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting an exciting research study, in collaboration with Pennington Biomedical Research Center, to investigate whether intermittent fasting or calorie restriction (i.e., losing weight) can improve health and slow the aging process.
If you are randomly selected to do calorie restriction, you may lose weight by eating less. If you are randomly selected to do intermittent fasting, you will fast for 16 hours per day and eat dinner by 6 pm about 6 days per week (1 break day per week). We want you to be successful: the study provides intensive coaching and support to help you successfully lose weight or practice intermittent fasting.
To qualify, you should:
Be 25-45 years old
Have a BMI between 22-30 Calculate your BMI here
Be healthy
Not currently taking any medications or supplements for chronic conditions
Not smoke, vape, or use tobacco products currently or within the last 6 months
Not currently participate in a regular program of heavy physical activity (e.g., jogging, running, or riding fast on a bicycle for 30 minutes or more per day)
The study involves collecting a medical history, body fat and bone scans, blood draws, urine collection, questionnaires, and other simple tests. Participation in the study will last approximately 7 months. Compensation of up to $1,500 is offered for the completion of this study. If you are interested in participating and think you may be eligible, please click the button below to screen online, call 205-934-1457, or email dial@uab.edu.