About the Study The iADAPT study is a 16-week study designed to determine which weight loss program features are most effective in people with a physical disability. Participants will follow one of two diets and may be given additional nutritional or exercise counseling. The study provides weekly coaching, body composition assessment, and lab work to assess diabetes and heart disease risk. Eligibility: Aged 18–75 Overweight/obese BMI Physical disability or mobility impairment Not currently on weight loss medications Reimbursement: Participants will receive up to $150 in compensation for their time. Participants: Come in person to the WHARF on Lakeshore Campus at the beginning and end of the four-month period for testing Receive weekly group coaching on lifestyle changes (via Zoom) May receive additional exercise and diet support as needed Will receive detailed body composition and metabolic assessments Contact Info Omer Faruq Telephone: 205-518-8292 Email: ofaruq@uab.edu

Participate in the PRISM-BP research study at UAB, investigating whether sharing personalized genetic risk scores can help people better control blood pressure. In this study, participants will attend 7 visits over 12 months. The study involves health checks, blood tests, urine samples, activity tracking, and wearing a 24-hour blood pressure monitor. Some participants will also receive their genetic risk score with counseling. Eligible participants must be 18–55 years old, have high blood pressure, and have no history of serious heart or kidney problems. Women cannot be pregnant or breastfeeding. Participants will be compensated up to $360 for completing study visits. Please e-mail Dr. Bal at harshvir6598@uabmc.edu or call us at 205-934-7936 if you are interested.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. In this study, participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Amrita at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-0649 if you are interested.

If you are overweight or obese and have Type 2 Diabetes you may qualify for a clinical research study. This clinical trial is studying an investigational medicine. We’re searching for adults aged 18+ years, with a BMI of 27 or greater, and who are keen to take part in clinical research. Qualified participants will receive no-cost study-related exam and investigational drug and may be compensated for time and travel. For more information, contact Tracie Thomas tthoma@uab.edu or 205-996-4015.

The UAB Department of Nutrition Sciences is conducting a nutrition and brain health study looking at whether an acute dose of a ketone supplement can improve cognitive function in individuals 60 and older. You may qualify if you are between the ages of 60-75 years, are healthy or have prediabetes, have NOT been diagnosed with Diabetes, are willing to consume a ketone supplement drink, and are willing to travel to UAB for 2 testing visits that include a PET-fMRI brain scan. Qualified participants will receive PET-fMRI scans upon request and monetary compensation for their time. For more information and to see if you qualify, please call or email sksweatt@uab.edu.

The UAB Department of Nutrition Sciences, in collaboration with Viking Therapeutics, is conducting a 78 week research study to look into how well VK2735, a GLP-1 and GIP combo investigational once weekly medicine, works at different doses in people with type 2 diabetes and overweight or obesity. Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-2689 or email at alp0029@uab.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. In this study, participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Amrita at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-0649 if you are interested.

Learn more about the CT-388-104 Study testing the safety and effectiveness of a selective GLP-1/GIP investigational drug for those living with overweight or obesity with type 2 diabetes. You may be able to join the CT-388-104 Study if you: Are 18 through 75 years old Have a body mass index (BMI) of 25 or above Have been diagnosed with type 2 diabetes Have tried to lose weight once or more through diet and exercise but without success There are other requirements for taking part in this study. The study team will go over these with you. If you qualify to join, you may receive at no cost: The investigational drug or placebo Close medical care and follow-up throughout the study Lifestyle management counseling Contact us to find out more about the CT-388-104 Study: Alex Rolling, CRC, RDalp0029@uab.edu205-996-2689

Do you want to make a difference for kids? More children are at risk for type 2 diabetes, and you can help us learn why. Type 2 diabetes is diagnosed when the body has problems with high blood sugar levels. This can lead to serious health problems if not identified and treated early. DISCOVERY is a study for children 9-14 years old who may be at higher risk of developing type 2 diabetes. What will happen in the study? In person and phone visits Lab tests Questionnaires Physical exams Glucose (blood sugar) monitors Join families across the US to help us make a difference for all children and young people! This study does not involve medications and there is no cost to you. You will be compensated for your time in this study. Contact us for more information:205-517-1351Discovery@uab.edu

Receive compensation and Free 20-Week Exercise Program. Eligible enrolled participants will receive: - Supervised exercise training at no cost- Blood pressure medication at no cost- Convenient parking at no cost- Compensation for timeIf you are interested, please call 205-996-3005 and mention The ACES Study or apply here -https://www.uab.edu/medicine/exercise/volunteer-clinical-trials/aces-trial.

The University of Alabama at Birmingham, Department of Family and Community Medicine, is conducting a 12-month research study to test the effectiveness of a diabetes management intervention. If you have type 2 diabetes, are 18 years or older, and self-identify as Black or African American, you may be eligible to participate. Participants will be compensated up to $300 for completing the study. For more information, please contact us at: 205-224-2567, or freedom@uabmc.edu, or fill out this pre-screening form and we will get in touch with you: https://redcap.link/freedom

Adults with Type 2 Diabetes needed for a study If you are between the ages of 18 -89 yrs and have type 2 diabetes you may be eligible to participate in a study exploring the reason why individuals who have diabetes have an increased risk of forming calcium oxalate kidney stones. Individuals who are obese, overweight, or normal weight are all welcome to the study. Participation involves eating study-provided meals for 4 days, providing urine and blood samples. Study meals are provided free of charge and additional compensation up to $140 is offered. For more information, call 205-934-5712 or email kidneystone@uabmc.edu or kidneystoneresearch@uabmc.edu.

You may be eligible to participate in the UAB’s Cardiovascular Research Biobank (CARBON), a repository of biological samples that will be used for future research about heart disease, diabetes, genomics, and more. Participants must be over the age of 18. The study will require one brief visit to UAB and collection of blood samples. Participants will be compensated. Please contact Nehal Vekariya at carbonstudy@uabmc.edu or 205-934-7173 if you are interested.

You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking sacubitril/valsartan or valsartan, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Vibhu Parcha, vparcha@uabmc.edu if you are interested. 

UAB Department of Nutrition Sciences is conducting a nutrition study looking at the effects of diet in adults with type 2 diabetes, high blood sugar, for less than 5 years. You may qualify if you are between the ages of 35-65, are African American or European American, are not using insulin, and are willing to travel to UAB for testing visits. Qualified participants will receive weekly groceries, personal health information, group support sessions with a Registered Dietitian, and monetary compensation for your time. For more information and to see if you qualify, please call 205-934-4386 or email LLG@uab.edu.

We are seeking volunteers with Type 2 Diabetes for a weight loss research study looking at the role of dietary protein in weight loss and the remission of type 2 diabetes. The study will last approximately 12 months. Participants will participate in a 16 week State of Slim group weight loss program and a 36 week State of Slim Next Steps weight loss maintenance program, with body composition scans and lab work at no charge. Participants will receive monetary stipends of $300 to reimburse for time and travel to study classes and study visits. You may qualify for this weight loss research study if you are nonvegetarian, 18 years of age or older, has Type 2 Diabetes diagnosed within the last 6 years, are overweight or obese with a BMI greater than or equal to 27. Must be willing to participate in weekly group weight loss classes for 16 weeks, bi-weekly weight loss maintenance classes for 36 weeks, and attend four study visits over 12 months at the Lakeshore Foundation Campus. Also is willing to regularly consume lean red meat or not consume any red meats. Please call (205)873-8241 or email cwyoder@uab.edu if you are interested.

The UAB Department of Nutrition Sciences is conducting a nutrition study looking at the effects of diet in Type 2 diabetes. You may qualify if you are ages 35-65, are African American or European American, have been diagnosed with Type 2 diabetes within the past 5 years, and are willing to travel to UAB for testing visits. Qualified participants will receive weekly groceries, personal health information, group support sessions with a Registered Dietitian, and monetary compensation for your time. For more information and to see if you qualify, please call 205-934-4386 or email LLG@uab.edu.

Healthy African American or Caucasian men and women ages 18-40 needed to participate in a research study about the effects of glucose on a protein in your blood — this protein is related to heart disease. Must have no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please email Dr. Nirav Patel, npatel@uabmc.edu if you are interested.

The UAB Division of Rheumatology and Immunology is conducting a study to research the effects of Rheumatoid Arthritis on muscle strength and insulin. To qualify, you must be between the ages of 35 and 65, not be diagnosed with diabetes or any other illness that may impair evaluation of study outcomes, and do not engage in a strength training program or vigorous exercise. All participants will be required to come to UAB for testing on 3 or more occasions and qualified RA participants will receive a 15-week regimen of the study drug. There is no charge for participation and all participants will receive compensation. For more information, and to see if you might be eligible to join, call (205) 934-4021.

You may qualify to participate in an international research study to evaluate the safety and tolerability of an investigational drug for patients with type 2 diabetes and kidney disease. Are you at least 18 years old? Do you have type 2 diabetes mellitus and a clinical diagnosis of kidney disease? Eligible study participants will receive study medications, blood pressure checks, physical exams, laboratory tests and ECG at no cost. Participants will  be reimbursed for time and travel. For more information, call the UAB Hypertension Program at 934-9281 or e-mail ccc-hlnresearch@mail.ad.uab.edu.