Do you struggle with anxiety, depression, or feel that your quality of life has suffered due to your HIV diagnosis? Researchers in the Department of Psychology at The University of Alabama at Birmingham are conducting a clinical trial of Acceptance and Commitment Therapy for the treatment of mental health concerns among men who have sex with men and are living with HIV. Volunteers will attend 8 weekly roughly 1 hour sessions of psychotherapy delivered via HIPAA-compliant Zoom by a doctoral student in Medical/Clinical Psychology at University of Alabama at Birmingham. Participants will receive $10 upon completion of initial intake session and an additional $15 upon completion of final therapy session. To participate, you must be an active patient of UAB's 1917 clinic. Complete this online screener to indicate interest: https://uab.co1.qualtrics.com/jfe/form/SV_8H8oWPLXTK532DQ Reach out to uabACThivtrial@gmail.com with any questions.

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at (205)934-0534 or email us at nauticalstudy@uabmc.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.

Are you between the ages of 18-60? The UAB Office of Psychiatric Research is actively recruiting participants for our studies and wants to connect with you on our research! Whether you are needing someone to talk to, or even have no history of mental health conditions and are just wanting to further knowledge within the medical and mental health field, we would love to get you involved!Our studies can be broken down into two different categories:1) TREATMENT STUDIES – Our Treatment Studies are designed to evaluate the effectiveness of new antidepressants on individuals living with Major Depressive Disorder or Treatment-Resistant Depression.2) NON-TREATMENT STUDIES – Our Non-Treatment Studies do NOT involve testing a new medication or intervention. Instead, these studies focus on understanding behaviors and experiences of mental health conditions via interviews, tests, or surveys.COMPENSATION IS PROVIDED!For more information, please reach out to the UAB Office of Psychiatric Research at (205) 934-2484 or go to: https://tinyurl.com/UABpsychiatricresearch and our team will be in contact with you shortly!

Join us at the Alabama Vaccine Research Clinic at UAB! We are seeking participants who were assigned male at birth, are 18 years or older, are not living with HIV, have had receptive anal intercourse (RAI) and regularly douche before intercourse. Participants must not have taken oral or injectable PrEP (pre-exposure prophylaxis) for 8 weeks prior to screening. Our clinical trial will help in the development of an on-demand PrEP in the form of a rectal douche. Your involvement will include simple procedures such as medical and sexual history collection, blood and urine sample testing, a physical exam, and receiving PrEP products in the form of an oral pill and a douche. Compensation will be available for your time and effort. If you are interested, please call 205-934-6777, 205-975-2839 or email avrc@uabmc.edu. You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/

Interested in being part of vision rehabilitation research for healthy older adults aged 50-59 to lay the foundation of using a new device? Here is an overview of what our study will involve! The purpose of this study? Calculate baseline data for Bioness Integrated Therapy System (BITS) and identify its clinical implications in treating visual impairments. Compare the baseline data of Bioness Integrated Therapy System (BITS) to Dynavision for visual scanning. Who are we looking for? Healthy adults aged 50-59 without physical, visual, or cognitive impairment and with no history of seizures or balance problems. Adults who are able to walk without assistive devices and are English speakers. What would you have to do in 60 minutes? Fill out a short survey for demographic data. Quick functional screening of upper extremities. Perform four tests on BITS. Perform four tests on Dynavision. Participants will receive a $25 gift card. To participate in the study, please fill out this short survey:https://uab.co1.qualtrics.com/jfe/form/SV_exEYGMKXxc230p0 For more information, please contact us at almulhim@uab.edu

We are looking for volunteers to participate in a clinical study to advance lupus treatment.If you are interested in seeing if you may qualify for an ongoing clinical study, please contact Christina Ndolo at cmndolo@uabmc.edu.

Study Information: Are you 18-60 years of age living with HIV, and want to be a part of a vaccine study? Is your viral load suppressed/undetectable? Are you able to receive a vaccine? Are you generally healthy? Are you willing to temporarily stop taking antiretrovirals? You may qualify for a study looking at testing an experimental HIV vaccine with an experimental adjuvant to see how the immune responses change among participants who do an antiretroviral analytical treatment interruption (ATI) compared to those who do not. Compensation at each study visit will be provided for time and travel. Transportation services are also available upon request. If interested, please email sspaulding@uabmc.edu.

University of Alabama at Birmingham is seeking cigarette smokers who would like to quit smoking for participation in a scientific research study. The research study involves free counseling and treatment provided in a comfortable, supportive setting. The study may involve ingestion of psilocybin, a psychoactive substance found in psychedelic mushrooms that have been used as a sacrament in various cultures. Some research studies have suggested that psychedelics, when administered under interpersonally supportive and well-prepared conditions, may be effective in helping people overcome addictions. Questionnaires, interviews, and biological measures of smoking will be used to assess the treatment's effects on mood and smoking. Participants will be compensated $50 per session. If you would like to discuss the possibility of volunteering, please call 205-996-1198, or go to www.quitsmokingbaltimore.org for more information about the study and to complete the online study prescreener for the UAB site. Confidentiality will be maintained for all applicants and participants.Volunteers must be 21 years of age or older, and must live within travel distance of the study site in Birmingham.

There is an ongoing psychedelic clinical research study evaluating the safety and efficacy of an intranasal study drug for patients with treatment resistant depression. To qualify patients need to be 18-75 years of age, failed to respond to an adequate dose & duration of at least 2 medicines for depression. If currently taking antidepressants, willing and able to discontinue. If eligible, study participants will be expected to abstain from illicit drugs for the duration of the trial & attend all study visits & follow instructions from the study doctor. Study examinations will be at no cost to you. For more information please contact 205-996-1198 or spremani@uab.edu

If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.

UAB researchers are looking for adults (ages 25-65) who are suffering from demoralization - feelings of hopelessness or meaninglessness - to participate in a research study evaluating a novel medication.To see if you qualify call 205-379-7527.

Help us find out by joining our study at UAB by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.

The Functional Outcomes from Diet in Multiple Sclerosis (FOOD for MS) study will test whether eating healthy foods and losing weight can improve physical function, pain, fatigue, mood, and sleep in adults with relapsing-remitting or secondary progressing MS. We will also explore the how diet impacts inflammation, immunity, and metabolic biomarkers that may contribute to MS symptoms and progression. Eligible participants must be 18-65 years old, diagnosed with Relapsing Remitting Multiple Sclerosis or Secondary Progressive Multiple Sclerosis, and be able to travel to one of our two study sites, Birmingham, Alabama or St. Louis, Missouri three times points over 8 months. Participants will be compensated $150 for completing all study visits and have their groceries provided for the length of the 8 month study. Please contact Kathryn Green at kathryngreen@uabmc.edu or by phone 205-319-1424 or Meghan Taylor at meghan13@uab.edu for more information and to see if you qualify.

Do you have a history of kidney stones? If you are 18 or older with a history of calcium oxalate kidney stones, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.For more information email kidneystone@uabmc.edu

f you are 18 or older and in good health, you may be eligible to participate in a research study. The goal of this study is to better understand how vitamin C is related to oxalate metabolism, an element of calcium oxalate kidney stone disease and how body weight impacts this. The study requires eating a study diet for 6 days, collecting 24-hr urines and blood samples with a one-day long visit at the UAB Clinical research unit. Study meals are provided free of charge and additional compensation up to $490 is offered.For more information email kidneystone@uabmc.edu

We are looking for people who identify as trans or cisgender, are 18-65 years of age and would like to take part in a research study examining the impact of gender identity, hormone levels and sex assigned at birth to pain sensitivity and immune cell activity. The commitment to this study will last approximately 3 hours where you will fill out questionnaires, have a single blood draw and take part in pain sensitivity testing. Participants must: Be free from certain health conditions (HIX+, cardiovascular disease, uncontrolled hypertension). Participants can be on HRT (hormone replacement therapy) or not. Participants will receive up to $100. To find out more about this study, call 205-834-3625 or email shinestudyuab@gmail.com.

The RECOVER study was designed in partnership with many of the nation’s top experts in treatment-resistant depression, and approved by Medicare, to provide additional evidence of the benefit of VNS Therapy. If the results confirm previous studies, Medicare and other insurers may start to cover it.People who participate in RECOVER will receive VNS Therapy and all study-related care at no cost to them. To join the RECOVER study, you must be 18 years orolder and:1. Currently depressed2. Have depression, or bipolar depression, that has lasted for at least two years or recurred several times3. Have tried at least four types of antidepressant treatments and not found them helpful4. Have Medicare Insurance