More than 100 different UAB researchers have been first authors on papers based on data from the REGARDS study, a long-running project to uncover the cause of stroke disparities in the United States. The secret to this success is a willingness to share that is built into the study's DNA, scientists say.

This long-running study proves that nice people finish first

Science always begins with a question, and Big Science poses big questions. At the turn of the millennium, one of the biggest conundrums in the health of America was the disparity in stroke deaths between Black and white individuals across the United States, and between residents of the South and people living in the rest of the country. Black people under age 75 were more than twice as likely to die from stroke than were white people, while people who lived in the South had a 40 percent higher risk of dying from stroke than their counterparts in other parts of the United States.

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Virginia Wadley (right) and George Howard (left)

In the ‘Stroke Belt,’ Erosion of Memory Is More Likely Too

People in a large area of the American South have long been known to have more strokes and to be more likely to die from them than people living elsewhere in the country.

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Suzanne Judd

New study calculates damage of food + lifestyle fails. What’s your score?

Hot sauce may burn the tongue, but the inner fire of inflammation brings real damage.

“We know inflammation is detrimental for heart disease, cancer and other chronic conditions,” said Suzanne Judd, Ph.D., a professor in the Department of Biostatistics. Research has demonstrated that diet and lifestyle choices contribute to inflammation. But which foods and choices do we mean, exactly?

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A REGARDS study examines factors associated with higher risk of incident hypertension among black adults

The high prevalence of hypertension (abnormally high blood pressure) among the US black population is a major contributor to disparities in life expectancy; however, the causes for higher incidence of hypertension among black adults are unknown. In this study, REGARDS investigators found that the most important factor contributing to differences in hypertension incidence between black and white participants was the Southern dietary pattern, accounting for 51.6% of the excess risk among black men and 29.2% of the excess risk among black women.

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Virginia Howard, Ph.D.

Do age and race differences determine risk of stroke in women and men?

A new REGARDS study suggests that white women were less likely to have a stroke than white men, but at age 75 and older, there was no difference in stroke risk between white women and men. In contrast, the study found that black women were at lower risk of stroke than black men only until age 64, with a similar stroke risk in the age group of 65 and older.

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