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Padgett LE and Tse HM. 2016. NADPH Oxidase-Derived Superoxide Provides a Third Signal for CD4 T cell Effector Responses. Journal of Immunology 197(5):1733-42   PMC4992601


Tse HM
, Kozlovskaya V, Kharlampieva, and Hunter CS. 2015. Mini-review: Directed differentiation and encapsulation of islet  beta-cells: recent advances and future considerations. Molecular Endocrinology 29(10):805-812. PMC4588727


Padgett LE, Anderson B, Liu C, Ganini D, Mason RP, Piganelli JD, Mathews CE, and Tse HM. 2015. Loss of NOX-Derived Superoxide Exacerbates Diabetogenic CD4 T cell Effector Responses in Type 1 Diabetes. Diabetes 64(12):4171-4183. PMC4657579


Kozlovskaya V, Xue B, Lei W, Padgett LE, Tse HM*, and Kharlampieva E. 2015. Hydrogen-Bonded Multilayers of Tannic Acid as Mediators of T cell Immunity. Advanced Healthcare Materials 4(5):686-694. PMC4390483. * co-corresponding author.


Padgett LE, Burg AB, Lei W, and Tse HM 2015. Loss of NADPH Oxidase-Derived Superoxide Skews Macrophage Phenotypes to Delay Type 1 Diabetes. Diabetes 64(3):937-946. PMCID: PMC4338593


Padgett LE, Burg AR, Lei W, Tse HM. 2014. Loss of NADPH Oxidase-Derived Superoxide Skews Macrophage Phenotypes to Delay Type 1 Diabetes. Diabetes. [Epub ahead of print] PMID:25288672


Bone RN, Gai Y, Magrioti V, Kokotou MG, Ali T, Lei X, Tse HM, Kokotos G, Ramanadham S. 2014. Inhibition of Ca2+-Independent Phospholipase A2 (iPLA2β) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice. Diabetes. [Epub ahead of print] PMID:25213337


Lei X, Bone RN, Ali T, Zhang S, Bohrer A, Tse HM, Bidasee KR, Ramanadham S. 2014. Evidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development. Endocrinology. 155(9):3352-64. PMID:25004092  PMCID:PMC4138580


Sawant A, Schafer CC, Jin TH, Zmijewski J, Tse HM, Roth J, Sun Z, Siegal GP, Thannickal VJ, Grant SC, Ponnazhagan S, Deshane JS. 2013. Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways. Cancer Res. 73(22):6609-20. PMID:24085788  PMCID:PMC3854493


Casazza K, Hanks LJ, Clines GA, Tse HM, Eberhardt AW. 2013. Diabetes-related impairment in bone strength is established early in the life course. World J Diabetes. 4(4):145-50. PMID:23961325  PMCID:PMC3746087


Kozlovskaya V, Zavgorodnya O, Chen Y, Ellis K, Tse HM, Cui W, Thompson JA, Kharlampieva E. 2012. Ultrathin polymeric coatings based on hydrogen-bonded polyphenol for protection of pancreatic islet cells. Adv Funct Mater. 22(16):3389-3398. PMID:23538331  PMCID:PMC3607452


Delmastro-Greenwood MM, Tse HM, Piganelli JD. 2014. Effects of metalloporphyrins on reducing inflammation and autoimmunity. Antioxid Redox Signal. PMID:23472672


Padgett LE, Broniowska KA, Hansen PA, Corbett JA, Tse HM. 2013. The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis. Ann N Y Acad Sci. 1281:16-35. PMID:23323860  PMCID:PMC3715103


Seleme MC, Lei W, Burg AR, Goh KY, Metz A, Steele C, Tse HM. 2012. Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice. Free Radic Biol Med. 52(9):2047-56. PMID:22361747  PMCID:PMC3711256


Lin MS, Tse HM, Delmastro MM, Bertera S, Wong CT, Lakomy R, He J, Sklavos MM, Coudriet GM, Pietropaolo M, Trucco MM, Piganelli JD. 2011. A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice. Immunol Res. 50(2-3):213-20. PMID:21717080


Thayer TC, Delano M, Liu C, Chen J, Padgett LE, Tse HM, Annamali M, Piganelli JD, Moldawer LL, Mathews CE. 2011. Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes. Diabetes. 60(8):2144-51. PMID:21715554   PMCID:PMC3142064


Sheng H, Spasojevic I, Tse HM, Jung JY, Hong J, Zhang Z, Piganelli JD, Batinic-Haberle I, Warner DS. 2011. Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. J Pharmacol Exp Ther. 338(3):906-16. PMID:21652782  PMCID:PMC3164343


Hager EJ, Piganelli JD, Tse HM, Gibson KM. 2012. Aberrant expression of costimulatory molecules in splenocytes of the mevalonate kinase-deficient mouse model of human hyper-IgD syndrome (HIDS). J Inherit Metab Dis. 35(1):159-68. PMID:21607759  PMCID:PMC3654530


Tse HM, Thayer TC, Steele C, Cuda CM, Morel L, Piganelli JD, Mathews CE. 2010. NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity. J Immunol. 185(9):5247-58. PMID:20881184   PMCID:PMC3190397


Batinic-Haberle I, Spasojevic I, Tse HM, Tovmasyan A, Rajic Z, St Clair DK, Vujaskovic Z, Dewhirst MW, Piganelli JD. 2012. Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities. Amino Acids. 42(1):95-113. Erratum in: Amino Acids. 42(1):115-6. PMID:20473774  PMCID:PMC3022969


Tse HM
, Thayer TC, Steele C, Cuda CM, Morel L, Piganelli JD, Mathews CE. 2010. NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity. J Immunol. 185(9):5247-58. PMID: 20881184


Batinic-Haberle I, Spasojevic I, Tse HM, Tovmasyan A, Rajic Z, St Clair DK, Vujaskovic Z, Dewhirst MW, Piganelli JD. 2010. Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities. Amino Acids. 42(1):95-113. PMID: 20473774


Sklavos MM, Bertera S, Tse HM, Bottino R, He J, Beilke JN, Coulombe MG, Gill RG, Crapo JD, Trucco M, Piganelli JD. 2010. Redox modulation protects islets from transplant-related injury. Diabetes. 59(7):1731-8. PMID: 20413509


Su D, Coudriet GM, Kim DH, Lu Y, Perdomo G, Qu S, Slusher S, Tse HM, Piganelli J, Giannoukakis N, Zhang J and Dong HH.  2009. FoxO1 Links Insulin Resistance to Pro-inflammatory Cytokine IL-1beta Production in Macrophages.  Diabetes, 58: 2624-2633. PMID: 19651810


Sheng H, Yang W, Fukuda S, Tse HM, Paschen W, Batinic-Haberle I, Crapo JD, Pearlstein RD, Piganelli JD, and Warner DS. 2009. Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.  Free Radical Biology and Medicine, 47: 917-923. PMID: 19631268


Milton-Sklavos MJ, Tse HM, and Piganelli JD. 2008. Redox Modulation Inhibits CD8 T cell Effector Function.  Free Radical Biology and Medicine 45:1477-1486. PMID: 18805480


Luppi P, Cifarelli V, Tse HM, Piganelli JD, and Trucco M. 2008. Human C-peptide antagonizes high glucose-induced endothelial dysfunction through the NF-kB pathway.  Diabetologia 51:1534-1543. PMID: 18493738


Cifarelli V, Luppi P, Tse HM, He J, Piganelli JD, and Trucco M. 2008. Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-kB activation in vascular smooth muscle cells.  Atherosclerosis 201:248-257. PMID: 18294642


Hager EJ, Tse HM, Piganelli JD, Gupt M, Baetscher M, Tse TE, Pappu AS, Steiner RD, Hoffmann GF, and Gibson KM. 2007. Deletion of a Single Mevalonate Kinase (Mvk) Allele Yields a Murine Model of Hyper-IgD Syndrome.  Journal of Inherited Metabolic Disease 30:888-895. PMID: 18008182


Tse HM
, Milton MJ, Schreiner S, Profozich JL, Trucco M, and Piganelli JD. 2007. Disruption Of Innate-Mediated Pro-Inflammatory Cytokine And Reactive Oxygen Species Third Signal Leads To Antigen-Specific Hyporesponsiveness.  Journal of Immunology 178:908-917. PMID: 17202352


Ge X, Piganelli JD, Tse HM, Bertera S, Mathews CE, Trucco M, Wen L, and Rudert WA. 2006. Modulatory Role of DR4- to DQ8-restricted CD4 T-Cell Responses and Type 1 Diabetes Susceptibility.  Diabetes 55:3455-3462. PMID: 17130492


Luppi P, Tse H, Lain KY, Markovic N, Piganelli JD, and DeLoia JA. 2006. Preeclampsia activates circulating immune cells with engagement of the NF-kappaB pathway. Am J Reprod Immunol 56 (2):135-144. PMID: 16836616


Bottino R, Balamurugan AN, Tse H, Thirunavukkarasu C, Ge X, Profozich J, Milton M, Ziegenfuss A, Trucco M, and Piganelli JD. 2004.  Response of Human Islets to Isolation Stress and the Effect of Antioxidant Treatment.  Diabetes 53:2559. PMID: 15448084


Tse HM
, Milton MJ, Piganelli JD. 2004. Mechanistic Analysis of the Immunomodulatory Effects of a Catalytic Antioxidant on Antigen Presenting Cells: Implication for Their Use in Targeting Oxidation-Reduction Reactions in Innate Immunity. Free Radic Biol Med 36:233. PMID: 14744635


Schott, W. H., B. D. Haskell, H. M. Tse, M. J. Milton, J. D. Piganelli, C. M. Choisy-Rossi, P. C. Reifsnyder, A. V. Chervonsky, and E. H. Leiter. 200). Caspase-1 Is Not Required for Type 1 Diabetes in the NOD Mouse. Diabetes 53:99. PMID: 14693703


Tse HM
, Josephy S, Chan E, Fouts D, Cooper A. 2002.  Activation of the Mitogen-Activated Protein Kinase Signaling Pathway is Instrumental in Determining the Ability of Mycobacterium avium to Grow in Murine Macrophages.  Journal of Immunology 168:825-833. PMID: 11777978


Tse H
, Gill RE. 2002.  Bypass of A- and B-Signaling Requirements for Myxococcus xanthus Development by Mutations in spdRJournal of Bacteriology 184(5):1455-1457. PMID: 11844778


Hager E, Tse H, Gill RE. 2001.  Identification and Characterization of spdR mutations that bypass the BsgA protease-dependent regulation of developmental gene expression in Myxococcus xanthusMolecular Microbiology 39(3):765-780. PMID: 11169116