Anatomic Pathology

Division Director: Vishnu V.B. Reddy, M.D.

Anatomic Pathologists diagnose disease based on the examination of cells, tissues, and organs from patients. Our Division conducts basic and translational research with the goal of increasing our understanding of the mechanisms driving organ-directed disease processes and of furthering diagnostic techniques such as immunohistochemistry and molecular diagnostics.

Special interests and expertise include: heart, lung, GI, liver, breast, kidney, genitourinary tract, ENT, non-neoplastic and neoplastic bone and skin disease, as well as specialized investigations of embryo and fetal disease.

Laboratory Medicine

Division Director: X. Long Zheng, M.D., Ph.D.

A division in the Department of Pathology, the Division of Laboratory Medicine engages in clinical service, medical research, and teaching. It oversees the analysis of components of blood, urine, body fluids, and tissue used for the diagnosis and management of disease. Approximately 5.2 million tests are conducted annually for the UAB Health System. The Division also offers outreach services to the UAB Health System Clinics, as well as to referring physician offices. Its medical and scientific staff is available for consultation regarding appropriate laboratory testing, coagulation, and blood banking (24 hours per day). The Division has 15 full-time faculty members with MD and/or PhD degrees. It also offers a one-year Fellowship in Blood Banking and Transfusion Medicine.

All sections of the UAB Hospital Laboratories are automated and integrated with the UAB Hospital information systems. Test results can be reported at remote sites. Division laboratories are accredited by CAP, AABB, JCAHO, CLIA, and ICC and are examined by internal and external quality assurance programs. Special expertise includes: clinical chemistry, toxicology, endocrinology, clinical microbiology, parasitology, mycology, clinical immunology, clinical hematology, coagulation, immune cytopenia, molecular diagnosis, transfusion medicine/blood banking, therapeutic apheresis, flow cytometry, and molecular genetics (in collaboration with the Department of Genetics at UAB).

Molecular and Cellular Pathology

Division Director: Ralph Sanderson, Ph.D.

Pathology's Division of Molecular and Cellular Pathology comprises 26 full-time faculty, at all ranks, with active research laboratories focused on the molecular mechanisms that underlie the development of disease.  Current areas of research in the Division include cardiovascular disease, cancer, bone biology, liver and digestive diseases, diabetes and insulin resistance, matrix biology, HIV and free radical biology.

Division faculty play leading roles in the UAB Comprehensive Cancer Center, Comprehensive Cardiovascular Center and the Center for Free Radical Biology. Division faculty are committed to graduate education, with leadership roles in the UAB Graduate in Biomedical Science program particularly in the Pathobiology and Molecular Medicine and Cancer Biology themes.

Genomics and Bioinformatics

Interim Division Director: Dr. Shuko Harada

 

Neuropathology

Division Director: Vishnu V.B. Reddy, M.D.

The UAB Division of Neuropathology is one of the largest and one of the most successful Neuropathology Divisions in the country.  The Division includes three faculty members.  The Division has a long-standing accredited NP fellowship training program.  The Division is committed to excellence in clinical service, scientific research, and teaching.

The Division of Neuropathology provides primary neuropathology diagnostic services to neurosurgeons at UAB Hospital and the Birmingham VA Hospital.  We also provide consultation service to Children’s Hospital and the Jefferson County Coroner/Medical Examiner Office.  We examine approximately 800 surgical neuropathology specimens per year of which approximately 500 are tumor related.  We also examine the brains from approximately 200 autopsy cases per year.  Four to six autopsy cases of suspected CJD are investigated per year.  Primary responsibility for signing out muscle (400 per year) and peripheral nerve (150 per year) biopsies lies in the Department of Neurology and our fellow is involved in the analysis of these cases.

The faculty of the Division of Neuropathology has a broad spectrum of research interests and expertise in nervous system diseases.  These research interests include the mechanisms involved in the pathogenesis of neurofibromatosis-associated peripheral nervous system neoplasms, the molecular regulation of apoptotic and autophagic neuronal cell death during nervous system development and in neuropathological conditions, the pathology of epilepsy, neuropsychiatric and neurodegenerative conditions and the environmental and genetic triggers for Lewy body formation and dopaminergic neuron death in Parkinson’s disease.

The UAB Division of Neuropathology has a long history of teaching excellence.  Drs. Powers, Carroll and Roth have each received multiple medical school “Teacher of the Year” honors at UAB and/or Washington University School of Medicine.  Further, the Neuropathology Section of the second year medical school course was voted by the Argus Society as “Best Correlative Pathology Section” for over ten straight years.  In addition to teaching medical students and the training of NP fellows, we actively participate in the teaching of Anatomic Pathology residents and residents in Neurology, Neurosurgery and Neuroradiology through both didactic sessions and intensive 4 week neuropathology rotations.

Forensic Pathology

Division Director: Gregory Davis, M.D.

The Division of Forensic Pathology provides forensic pathology services to Jefferson County, Alabama (Birmingham and surrounding region) in a medical examiner system. The pathologists perform approximately 650 postmortem examinations annually through the Jefferson County Coroner/Medical Examiner Office, including approximately 120 homicides and 240 accidents. The pathologists provide consultation on these cases to the families of the decedents, and to police and attorneys when appropriate. The pathologists testify approximately 40 times per year in criminal and civil trials related to the deaths investigated by the office. The division has its own investigative staff, autopsy assistants, clerical staff, and toxicology services.

The three pathologists in the division are all Diplomates of the American Board of Pathology in forensic pathology. The division is one of a handful of forensic pathology divisions fully incorporated into the Department of Pathology in an academic medical center, and the division offers a one-year fellowship in forensic pathology.