Areas of Interest
Idiopathic Pulmonary Fibrosis, Primary Open-Angle Glaucoma, Pulmonary and Ocular Mechanobiology
Dr. Zhou currently serves as a PLOS ONE editorial board member, a grant reviewer for the American Heart Association (AHA), and a grant reviewer for the Department of Defense (DoD). He has served on ATS International Conferences as chair, co-chair, and facilitator and has also served on the program committee of the ATS Assembly on Respiratory Structure and Function (RSF).
Dr. Zhou's lab also works to determine cellular responses to intraocular pressure-generated mechanical strain that drive ECM remodeling in lamina cribosa cells and scleral fibroblasts harvested from clinical-records-confirmed normal and glaucomatous human donor eyes. Progressive remodeling of load-bearing connective tissues, like lamina cribosa and sclera, at the optic nerve head, is a defining feature of glaucoma. This remodeling alters the microenvironment of the retinal ganglion cell (RGC) axons traversing the ONH and is believed to be a direct cause of the axon loss and death of RGCs. Intraocular pressure is currently the only known modifiable risk factor for glaucoma.
Dr. Zhou's Lab is currently funded by the NIH/NHLBI, AHA, ATS, and the EyeSight Foundation of Alabama (ESFA).
Education & Training
Wuhan University, Wuhan, Hubei, China
Kyushu University, Fukuoka, Japan
University of Alabama at Birmingham, Birmingham, AL