Heflin Center for Genomic Science

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Welcome to the Heflin Center for Genomic Sciences

Welcome to the Heflin Center for Genomic Sciences (HCGS). The Heflin Center was founded in 2002 as a University Wide Interdisciplinary Research Center (UWIRC) with the goal of enhancing resources to enable UAB investigators to incorporate genetic and genomic approaches in their research. 

Genomics Opportunities

Genomics – study of the structure and function of the entire complement of genetic information in the cell – is catalyzing rapid advances in both biology and medicine. In biology, genomics is illuminating the pathways of cellular development and function, as well as patterns of evolution at the population level. In medicine, genomics has revolutionized diagnosis of rare disease, sometimes revealing new therapies. Cancer is due to accumulation of mutations in multiple genes and can define the landscape of these changes to guide treatment. Genomics is also providing clues to the genetic contributors to common diseases such as hypertension and diabetes, providing insights into causes of these problem. Genomic approaches will increasingly be integrated across all of medicine, helping prevent disease or provide targeted treatments. We are also developing the ability to edit genomic information for therapeutic benefit. Although this rises complex ethical questions, it also offers new approaches to improving quality of life for those with genetic disorders.

The Heflin Center provides a significant amount of outreach in genomics for UAB and the community. The regularly scheduled series are listed below: 

Bioethics Seminar Series | 2nd Wednesday of the month | 3 - 4 p.m. 

Genomic Medicine Seminar Series | 1st and 3rd Wednesday of the month | 3 - 4 p.m. 

Genetics and Genomics Immersion Course | 3-day course each fall and spring 

Featured Events:

Non-Coding RNA Symposium
Friday November 3, 2017
8:00 AM - 4 PM
Finley Conference Center
NON CODING RNA SYMPOSIUM 002We invite our junior faculty, resident trainees, postdoctoral fellows, and graduate students, undergraduate students to submit an abstract of their original ncRNA research for presentation as
a poster at this year’s symposium. Prizes will be awarded for the top posters.
Abstract Submission Opens: 8:00 am – Monday, September 11, 2017
Abstract Submission Deadline: 5:00 pm – Friday, October 13, 2017 (no exceptions)

More information.


Upcoming Events

Genomics Core Laboratories (GCL)

The GCL provides Next Generation Sequence analysis, whole genome and targeted gene expression analysis, high- and low-throughput whole genome and custom genotyping, whole genome methylation analysis, and standard Sanger sequencing analysis to UAB investigators as well as individuals outside of the UAB system.