Research tools developed by University of Alabama at Birmingham (UAB) investigators continue to support scientific discovery long after they are created. Through licensing agreements managed by the Bill L. Harbert Institute of Innovation and Entrepreneurship (HIIE), these tools help researchers around the world advance their work.
Among the most licensed research tools in the HIIE’s portfolio are antibodies, proteins that recognize and bind to specific biological targets. Scientists use antibodies to identify proteins, study disease pathways, and validate research findings.
Antibodies that are available at HIIE have been generated by UAB faculty and staff members at UAB via traditional methods - creating specialized cells called hybridomas. “Those cells can be preserved for long periods of time and serve as a renewable source for producing antibodies that researchers need,” said Stephanie Moore, Ph.D., Antibody Portfolio Manager at the HIIE.
Antibodies are among the most licensed research tools in the HIIE’s portfolio.
Research organizations and companies typically license these antibody-producing cell lines for research-use-only applications. However, in some cases, underlying technology may also support future diagnostic or therapeutic development.
In addition to antibodies, UAB licenses a variety of research tools, including specialized cell lines, mouse models, and bacterial strains. These resources are designed to help scientists study diseases, test hypotheses, and develop new approaches to treatment.
Unlike many inventions that rely primarily on patent protection, research tools often derive their value from being unique and difficult to recreate. Licensing allows these materials to reach a broader research community while preserving their connection to the discoveries made at UAB.
Research tools also represent an important source of licensing revenue for the HIIE. Revenue generated through these agreements helps support the university’s efforts to protect, manage, and commercialize innovation developed by UAB researchers.
Though they often work behind the scenes, research tools play a critical role in advancing science, Moore said.
“Research tools are an important part of our portfolio, and they bring in an appreciable amount of revenue for the HIIE,” Moore said.
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-- July 9, 2026