10 - 11 a.m.



This seminar series is developed and sponsored by the UAB informatics Institute. It educates individuals on research innovations in biomedical informatics. 

There are two tracks: Clinical Informatics (1st and 3rd Fridays) and Bioinformatics (2nd and 4th Fridays). 

Clinical informatics seminars focus on the application of informatics for improving healthcare delivery and using health data for research. It includes diverse topics such as design, implementation, and clinical decision support.

Bioinformatics seminars present late-breaking computational techniques, tools and applications. It includes genomics and other -omics.

Some areas of informatics, such as precision medicine, natural language processing and image processing, span clinical informatics and bioinformatics and have greater crossover appeal. Presentations in these areas may be held in either 1st/3rd or 2nd/4th Fridays.

In addition to educating, we also strive to make these seminars social gathering places for the UAB clinical informatics and bioinformatics communities. We encourage you to attend to learn more about biomedical informatics and related disciplines and discover new opportunities for collaboration.


Jake Chen - Chair
Amy Wang - Moderator for 2022-2023 series

Bioinformatics Steering Committee

Jake Chen 
Zechen Chong 
David Crossman
Curtis Hendrickson         
Elliot Lefkowitz
Merry-Lynn McDonald
Hemant Tiwari

Clinical Informatics Steering Committee

Eta Berner
James Cimino
Tiago Colicchio
Tony Fargason
Jacqueline Moss
Bunyamin Ozaydin
Marisa Wilson
Amy Y. Wang

Click here to sign up for future PowerTalk Series updates

Upcoming Informatics Institute PowerTalk Seminars

Register for the powertalks at the links below for the individual seminar. Once you have registered, you will receive a confirmation email with the information for joining the meeting.

Friday, Feb 10, 2023 | Bioinformatics

"Acing the New NIH Data Sharing Requirement with U-BRITE" 

Jake Chen, Ph.D.
Professor of Genetics and Computer Science
Associate Director and Chief Bioinformatics Officer, UAB Informatics Institute
UAB Heersink School of Medicine

Zhandos Sembay, M.S.
Informatics Software Developer, UAB Informatics Institute
UAB Heersink School of Medicine 

Friday, Feb 17, 2023 | Clinical Informatics

"From Lab to Bedside: A Team Science Approach for Translational Natural Language Processing for Clinical Decision Support" 

Majid Afshar, M.D., MSCAR
Assistant Professor, Department of Medicine 
Division of Allergy, Pulmonary and Critical Care Medicine and Department of Biostatistics and Medical Informatics
Co-Director, Critical Care Medicine Data Science Lab
University of Wisconsin School of Medicine and Public Health
Physician Informaticist and Pulmonary and Critical Care Physician, UW Health 

Friday, Feb 24, 2023 | Bioinformatics

"Distributed Representation of Biological Concepts"

W. Jim Zheng, Ph.D.
Professor, School of Biomedical Informatics
Founding Direcotr, Data Science and Informatics Core for Cancer Research 
Director, Bioinformatics and High Performance Computing Service Center
Associate Director, Center for Computational Biomedicine
The University of Texas Health Science Center at Houston 

Friday, Mar 3, 2023 | Clinical Informatics

"Expanding Clinical Informatics Literacy and Workforce Capacity through Provider Builder Programs" 

Wayne H. Liang, M.D., M.S.
Director of Informatics Education and Outreach at Children's Healthcare of Atlanta
Pediatric Hematologist/Oncologist, Aflac Cancer & Blood Disorders Center
Assistant Professor of Pediatrics, Emory University School of Medicine

Friday, Mar 10, 2023 | Bioinformatics 


Zechen Chong, Ph.D.
Associate Professor of Genetics and Scientist, Informatics Institute
UAB Heersink School of Medicine 

Friday, Mar 24, 2023 | Bioinformatics

"Computation Screen to Identify Potential Targets for Immunotherapeutic Removal of Specific Cell Types" 

Avi Ma'ayan, Ph.D.
Mount Sinai Endowed Professor in Bioinformatics
Professor, Department of Pharmacological Sciences 
Director, Mount Sinai Center for Bioinformatics
Icahn School of Medicine at Mount Sinai 

Friday, Mar 31, 2023 | Bioinformatics

"Proteogenomics Presents New Avenues for Tumor Systems Biology"

Chen Huang, Ph.D.
Assistant Professor of Genetics
Scientist, Precision Medicine Institute and O'Neal Comprehensive Cancer 
UAB Heersink School of Medicine 

Bioinformatics Seminar Archive

  • 2023

    Friday, January 13 | Bioinformatics

    Reverse-Engineering Regulatory Mechanisms from scRNA-seq and scATAC-seq”

    Emily Miraldi, Ph.D. 
    Assistant Professor, University of Cincinnati, Department of Pediatrics
    Divisions of Immunobiology and Biomedical Informatics
    Cincinnati Children’s Hospital

    Friday, January 27 | Bioinformatics

    "Machine Learning and Network Biology Applications in Genomics"

    Ece (Gamsiz) Uzun, Ph.D.
    Director of Clinical Bioinformatics, Lifespan Academic Medical Center
    Assistant Professor of Pathology and Laboratory Medicine
    The Warren Alpert Medical School of Brown University 

  • 2022

    Friday, December 9 | Bioinformatics

    "DEPOT: Graph Artificial Intelligence to Reveal Health Trajectories of Chronic Kidney Disease for Precision Medicine”

    Jing Su, Ph.D.
    Assistant Professor and Director of Data Management Services
    Department of Biostatistics and Health Data Science
    Associate Director of Real-world Data, Biostatistics & Data Management Core
    Simon Comprehensive Cancer Center
    Indiana University School of Medicine

    Friday, November 11 | Bioinformatics

    "Multiscale Modeling of Biomolecular Networks"

    Yu "Brandon" Xia
    Professor, Department of Bioengineering
    Canada Research Chair in Computational and Systems Biology, McGill University

    Friday, October 28 | Bioinformatics

    "Virus Surveillance: Tools to Classify the Unknown"

    Elliott J. Lefkowitz, Ph.D. 

    Professor, Department of Microbiology
    Co-Director, Undergraduate Bioinformatics Program
    Director of Bioinformatics, Center for Clinical and Translational Science
    Director, Bioinformatics Core, Microbiome Facility
    UAB Heersink School of Medicine

    Friday, October 14 | Bioinformatics

    "Harnessing Bulk and Single Cell Omics Data for the Discovery of Biomarkers in Cancer"

    Chindo Hicks, Ph.D.
    Director, Bioinformatics and Genomics Program
    Professor, Department of Genetics
    LSU Health Sciences Center New Orleans School of Medicine 

    Friday, September 30 | Bioinformatics

    "An Integrated Approach to Ovarian Cancer Diagnostics and Therapeutics"

    John F. McDonald, Ph.D.

    Director, Integrated Cancer Research Center
    Professor, School of Biological Sciences, Georgia Institute of Technology
    Chief Scientific Officer, Ovarian Cancer Institute

    Friday, September 9 | Bioinformatics

    "Using AI-Algorithms to Advance Drug Discovery for Neglected Parasitic Diseases"

    Rahul Singh, Ph.D
    Professor, Department of Computer Science
    San Francisco State University

    #DataMatters - Leveraging Big Data for Cancer Discovery and Impact

    Jill S. Barnholtz-Sloan, Ph.D
    Associate Director for Informatics and Data Science (IDS)
    Center for Biomedical Informatics and Information Technology (CBIIT)
    Senior Investigator, Trans-Divisional Research Program (TDRP)
    Division of Cancer Epidemiology and Genetics (DCEG)
    National Cancer Institute (NCI)

    Friday, April 8 | Bioinformatics

    Predicting Isoform Functions via Deep Learning and Refinement of Interaction Networks

    Tao Jiang, PhD
    Distinguished Professor
    Department of Computer Science and Engineering
    University of California, Riverside

    Friday, March 25 | Bioinformatics

    Data-driven Informatics Research for Precision Oncology

    Qianqian Song, PhD,
    Assistant Professor of Cancer Biology
    Wake Forest School of Medicine

    Friday, February 25 | Bioinformatics

    Machine Learning Finds New Insights in Cardiac Regeneration

    Thanh Nguyen, PhD
    Postdoctoral Fellow, Dept. of Biomedical Engineering and Informatics Institute
    UAB Heersink School of Medicine

    Friday, February 11 | Bioinformatics

    Functional Genomics Downstream Analysis and Common Informatics Tools

    Zongliang Yue, PhD
    Postdoctoral Fellow, Informatics Institute
    UAB Heersink School of Medicine

    Friday, January 28 | Bioinformatics

    “Genome-Guided Rare Disease Diagnosis and Drug Targeting Strategies”

    Brittany N. Lasseigne, PhD
    Assistant Professor, Department of Cell, Developmental and Integrative Biology
    Associate Scientist, O'Neal Comprehensive Cancer Center
    Scientist, Hugh Kaul Precision Medicine Institute
    Scientist, Informatics Institute

  • 2021
    Friday, November 12 | Bioinformatics

    “Translating Big Data to Effective Cancer Therapy”

    Aik Choon Tan, PhD
    Vice Chair, Department of Biostatistics and Bioinformatics
    Moffitt Cancer Center

    Friday, November 5 | Bioinformatics

    “Facilitating Collaborative Research: Data Harmonization and Pooling”

    Eneida A. Mendonca, MD, PhD, FAAP, FACMI

    Vice President for Research Development and Interim Director, Center for Biomedical Informatics
    Regenstrief Institute, Inc.
    Professor of Pediatrics and Biostatistics, Indiana University School of Medicine
    Friday, October 22 | BioInformatics

    “Data Science Sherpas: UAB Research and the Journey to the Computer”

    Blake Joyce, PhD
    Data Science Manager
    UAB Research Computing

    Friday, October 8 | Bioinformatics

    “From Collecting Multi-Omic Data to Inferring Meaning”

    Ewy A. Mathé, PhD
    Director of Informatics, Division of Preclinical Innovation
    DPI Cores
    National Center for Advancing Translational Sciences (NCATS)
    National Institute of Health

    Friday, September 24 | Bioinformatics

    “Harnessing Public Genomics Big Data to Gain Functional Insights on Complex Diseases”

    Zhaohui "Steve" Qin, PhD, MS
    Professor, Department of Biostatistics and Bioinformatics
    Rollins School of Public Health
    Emory University

    Friday, September 10 | Bioinformatics

    “Identifying Viruses, their Integration sites, and Regulatory Factors in Host Genomes”"

    Zhongming Zhao, PhD, MS.
    Chair Professor and Director, Center for Precision Health
    School of Biomedical Informatics
    University of Texas Health Science Center at Houston

    Friday, August 27 | Bioinformatics

    "Using the Wisdom of Crowds to Address Computational Grand Challenges in Biomedicine"

    Gustavo Stolovitzky, Ph.D.
    Program Director, Translational Systems Biology and Nanobiotechnology
    Thomas J. Watson Research Center
    DREAM Challenges Founding Chair Emeritus and Director
    IBM Exploratory Life Sciences Council Chair

    Friday, April 30 | Bioinformatics

    “Computational Pathology and Integrative Genomics for Cancer Research”
    Kun Huang, Ph.D., FAIMBE
    Professor and Vice-Chair for Data Science, Department of Biostatistics and Health Data Science
    Precision Health Initiative Chair for Genomic Data Science
    Director of Data Science and Informatics, Precision Health Initiative
    Assistant Dean for Data Science
    Associate Director of Data Science, Simon Comprehensive Cancer Center
    Indiana University School of Medicine
    Senior Investigator, Regenstrief Institute

    Friday, April 9

    “Beyond BERT: Learning Representations for Clinical NLP”
    Timothy Miller, Ph.D.
    Assistant Professor of Pediatrics and Computational Health Informatics Program (CHIP)
    Harvard Medical School

    Friday, March 26

    “The Collaboration Structures of Critical Care Teams and Patient Outcomes: A Retrospective Network Analysis”
    You Chen, Ph.D.
    Assistant Professor, Department of Biomedical Informatics
    Vanderbilt University Medical Center
    OHPEN Laboratory

    Friday, March 12

    “Brain Imaging Genetics: Integrated Analysis and Machine Learning”
    Li Shen, Ph.D., FAIMBE
    Professor of Informatics
    University of Pennsylvania Perelman School of Medicine
    Shen Lab

    Friday, February 26

    “Adapting Natural Language Processing Models Across Clinical Domains”
    Steven Bethard, Ph.D.
    Associate Professor
    School of Information
    University of Arizona

    Friday, February 12

    "Multi-omic Analysis of Health and Disease Across Thousands of People"Nathan Price, Ph.D.
    Co-CEO, Onegevity Health
    Professor, Institute for Systems Biology
    Co-Director, Hood-Price Integrated Laboratory for Systems Biomedicine

    Friday, January 22 

    "An Evidence-based Network Approach to Recommending Targeted Cancer Therapies"
    Simina Boca, Ph.D.
    Associate Professor
    Department of Oncology and Department of Biostatistics, Bioinformatics and Biomathematics
    Georgetown University Medical Center

  • 2020
    December 11, 2020

    "Meta-Learning for Cancer Prediction and Survival Analysis"
    Aidong Zhang, Ph.D.
    Computer Science and Biomedical Engineering
    University of Virginia

    November 13, 2020

    "Application of Single-Cell Data Analysis in Autoimmune Disease"
    Min Gao, Ph.D.
    Assistant Professor
    Department of Medicine - Cardiovascular Disease
    Associate Scientist
    Informatics Institute

    October 30, 2020

    "Lessons from COVID-19: How Are Data Science and AI Changing Future Biomedical Research?"
    Jake Chen, Ph.D.
    Professor of Genetics and Computer Science
    Associate Director of Informatics Institute
    Chief Bioinformatics Officer
    UAB Heersink School of Medicine

    October 23, 2020

    "Getting to the Edge of Biological Networks"
    Shahid M. Mukhtar, Ph.D.
    Associate Professor
    Departments of Biology and Surgery
    Nutrition Obesity Research Center
    UAB Heersink School of Medicine

    October 9, 2020

    "Genomic Tools for Third-Generation Sequencing Data Analysis"
    Zechen Chong, Ph.D.
    Assistant Professor of Genetics and Scientist
    Informatics Institute
    UAB Heersink School of Medicine

    September 25, 2020

    "Community-Relative Distance with Applications to Bioinformatics"
    Ryan Melvin, Ph.D.
    Assistant Professor of Surgery
    Department of Anesthesiology
    UAB Heersink School of Medicine

    September 11, 2020

    "Understanding the Impact of Social Determinants of Health on the COVID-19 Pandemic"
    Ramaraju Rudraraju, Ph.D.
    Assistant Professor of Surgery
    Division of Cardiothoracic Surgery
    UAB Heersink School of Medicine

    May 8, 2020

    “From ‘Big Data’ to ‘Little Data’ — From Information Disarray to Action”
    William M. Tierney, M.D.
    Professor, Department of Population Health
    Chair, Department of Population Health
    Dell Medical School
    The University of Texas at Austin

    April 24, 2020

    “De-identification of UAB Clinical Text using Transfer Learning”
    John D. Osborne, Ph.D.
    Assistant Professor
    UAB Heersink School of Medicine
    Informatics Institute

    April 10, 2020

    “Bioinformatics for B-Cell Receptor Repertoire Sequencing Studies”
    Alexander Rosenberg, Ph.D.
    Associate Professor
    Department of Microbiology
    Informatics Institute
    UAB Heersink School of Medicine

    March 27, 2020

    "Mining and Prediction of Gene Functions for Systematic Study of the Genotype-Phenotype Map"
    Nilesh Kumar

    Ph.D. Student
    UAB Department of Biology

    "The Systeomics of Arsenical Injury"
    Bharat Mishra
    Ph.D. Student
    UAB Department of Biology

    March 6, 2020

    Topic: “The Coronavirus (COVID-19) Outbreak and Data-driven Healthcare: An Informatics Perspective”
    Speaker: Jake Chen, Ph.D.
    Affiliation: Professor, Department of Genetics, Chief Bioinformatics Officer, Associate Director
    Informatics Institute, UAB Heersink School of Medicine

    February 14, 2020

    Topic: "Deep Learning-driven Distance-based Ab Initio Protein Structure Prediction"
    Speaker: Jianlin Cheng, Ph.D.
    Affiliation: William and Nancy Thompson Professor in Electrical Engineering and Computer Science, University of Missouri

    January 24, 2020

    Topic: "Omics Approaches for Insight to Skeletal Muscle Wasting and Weight Loss in COPD"
    Speaker: Merry-Lynn McDonald, Ph.D.
    Affiliation: Director of Integrative ‘Omics and Assistant Professor, UAB Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine

    January 10, 2020

    Topic: "Genomics, Machine Learning, and Osteoporosis Risk Assessment"
    Speaker: Qing Wu, ScD, MSPH, MS, MB
    Affiliation: Associate Professor of Biostatistics, Department of Environmental & Occupational Health, School of Public Health and Nevada Institute of Personalized Medicine, University of Nevada, Las Vegas

  • 2019

    December 13, 2019

    Topic: "Research Computing: Building Gateways To Science"
    Speaker: Ralph Zottola, Ph.D.
    Affiliation: Assistant Vice-President for Researching Computing, Chief Architect for UAB Research Computing Applications

    November 22, 2019

    Topic: "Polygenic Risk Scores: Are They GPS for Clinical Practice?"
    Speaker: Hemant Tiwari, Ph.D. 
    William “Student” Sealy Gosset Endowed Professor, Department of Biostatistics, Section on Statistical Genetics, UAB School of Public Health

    October 25, 2019

    Topic: "AI-Informatics in Biomedicine: Find the Balance in Marriage"
    Speaker: Thanh Nguyen, Ph.D.
    Postdoctoral Fellow, UAB Heersink School of Medicine

    October 11, 2019

    Topic: "Control-Alter-Delete: Gene Regulatory Mechanisms in Brain Function and Disease"
    Speaker: Jeremy Day Ph.D.
    Associate Professor, Department of Neurobiology, UAB Heersink School of Medicine

    September 13, 2019

    Topic: "Bioinformatics for Single-cell Analysis: A Review of Computational Biology Trends and Application Opportunities"
    Speaker: Jake Chen, Ph.D.
    Affiliation: Professor, UAB Heersink School of Medicine, Department of Genetics and Computer Science, Associate Director of Informatics Institute, Chief Bioinformatics Officer

    May 24, 2019

    Topic: "Predicting genetic effect of missense variants using deep learning"
    Speaker: Yufeng Shen, Ph.D.
    Affiliation: Assistant Professor, Department of Systems Biology, Department of Biomedical Informatics, Columbia University

    May 10, 2019

    Topic: "A New Mathematical Framework for Convergence Computations"
    Speaker: Murat Tanik, Ph.D.
    Affiliation: Professor and Chair, UAB Department of Electrical and Computer Engineering, Wallace R. Bunn Chair of Telecommunications

    April 26, 2019

    Topic: "Whole-exome sequencing approach to select genes related to left ventricular hypertrophy in African Americans." 
    Speaker: Ryan Irvin, Ph.D.
    Affiliation: Associate Professor in the Department of Epidemiology, School of Public Health, UAB

    March 22, 2019

    Topic: "Privacy-preserving Techniques for Sharing and Analyzing Human Genomic Data"
    Speaker: Casey Greene, Ph.D.
    Affiliation: Assistant Professor, Department of Pharmacology, University of Pennsylvania

    February 8, 2019

    Topic: "Strategies to Study Rare Diseases with 'Big Data'"
    Speaker: Haixu Tang, Ph.D.
    Affiliation: Director, Data Science Academic Programs, Professor of Informatics and Computing, Indiana University Bloomington

    January 25, 2019

    Topic: "Biological discoveries through bioinformatics analysis and research"
    Speaker: Sheng Liu, Ph.D.
    Affiliation: Junior Faculty, Indiana University Department of Medical & Molecular Genetics

    January 11, 2019

    Topic: "L-2-Hydroxyglutarate in Renal Cancer: Epigenetic Mechanisms and Liabilities"
    Speaker: Sunil Sudarshan, M.D.
    Affiliation: Associate Professor, UAB Department of Urology

  • 2018

    December 14, 2018

    Topic:  "The UAB Undiagnosed Diseases Program: Bioinformatic Applications in Rare Disorders" 
    Speaker:  Bruce Korf, M.D., Ph.D.
    Affiliation: Wayne H. and Sara Crews Finley Chair in Medical Genetics, Chief Genomics Officer, UAB Medicine, Co-Director, UAB-HudsonAlpha Center for Genomic Medicine, Associate Director for Rare Diseases, Hugh Kaul Personalized Medicine Institute

    November 16, 2018

    Topic: “From linear organization to the 3D genome architecture” 
    Speaker: Yichao Li, Ph.D.
    Affiliation: Research Assistant, Ohio University School of Engineering and Computer Science

    October 26, 2018

    Topic: "Exploring the -Omics of Glioblastoma Using Patient-Derived Models of Cancer"
    Speaker: Christopher Willey, M.D., Ph.D.
    Affiliation: Director, UAB Kinome Core, Associate Professor, UAB Radiation Oncology

    October 12, 2018

    Topic: "Unraveling the meiotic recombination landscape in individual human genomes"
    Speaker: Peng Xu, Ph.D.
    Affiliation: Postdotoral Fellow, UAB Informatics Institute

    September 28, 2018

    Topic: "From chaos, DRAMA: Data-driven Research for Advanced Modeling and Analysis"
    Speaker: Jeremy Blackburn, Ph.D.
    Affiliation: Assistant Professor, UAB Department of Computer Science

    September 14, 2018

    Topic: “Computational prediction and modeling for protein-drug and protein-protein interactions”
    Speaker: Daisuke Kihara, Ph.D.
    Affiliation: Professor, Department of Biological Sciences and Department of Computer Sciences, Purdue University

    August 24, 2018

    Topic: "Deep Learning and Clustering Algorithms for Protein Scoring"
    Speaker: Debswapna Bhattacharya, PhD
    Affiliation: Assistant Professor, Auburn University

    August 10, 2018

    Topic: "Context fear memory formation is regulated by hippocampal lncRNA-mediated histone methylation changes"
    Speaker: Anderson Butler 
    Affiliation: Ph.D. candidate in GBS Cell, Molecular & Developmental Biology Program and Graduate student in Lubin Lab

    July 27, 2018

    Topic: "HLA Population Genetics and Informatics to Optimize the Kidney Allocation System"
    Speaker: Loren Gragert, Ph.D.
    Affiliation: Assistant Professor, Tulane University

    July 22, 2018

    Topic: "Predicting regulatory variants with large-scale multi-omics data"
    Speaker: Li Chen, Ph.D.
    Affiliation: Assistant Professor, Auburn University

    July 13, 2018

    Topic: "Implementation of Next Generation Sequencing (NGS) Testing in Precision Oncology Advantages and Challenges"
    Speaker: Shuko Harada, MD
    Affiliation: Associate Professor, UAB Pathology

    May 25, 2018

    Topic: "Towards the ultimate diagnostics: NGS of immune repertoire"
    Speaker: Jian Han, MD, PhD
    Affiliation: Faculty Investigator, HudsonAlpha Institute for Biotechnology

    May 11, 2018

    Topic: "Comparative and evolutionary genomics of allelic imbalance in mammals"
    Speaker: Xu Wang, Ph.D.
    Affiliation: Assistant Professor, Auburn University

    April 27, 2018

    Topic: "Integrating high-throughput drug screening with targeted deep sequencing reveals novel treatment strategies for chemoresistant acute myeloid leukemia"
    Speaker: Miranda Burnette, Ph.D.
    Affiliation: T32 Fellow, UAB Department of Microbiology

    March 23, 2018

    Topic: "An Introduction to Applied Longitudinal Data Analysis"
    Speaker: Lloyd J. Edwards, PhD
    Affiliation: Professor and Chair, Deparment of Biostatistics School of Public Health

    Abstract: Longitudinal studies, in which outcomes are measured repeatedly over time on the same subject, are widely conducted in various applications and often provide better insights about the processes of interest than cross-sectional studies. Longitudinal studies allow addressing questions about changes over time in the response and changes in the relationship of the response to subjects' characteristics. We present an introduction to applied longitudinal data analysis that is meant to introduce features of longitudinal data and available statistical techniques for analyzing the data.

    March 9, 2018

    Topic: "Roles of Alternative Splicing in Complex Diseases"
    Speaker: Yunlong Liu, Ph.D.
    Affiliation: Professor, Indiana University School of Medicine

    February 23, 2018

    Topic: Integrating multidimensional data to catalyze translation of GWAs finds to biology and therapeutics
    Speaker: Bingshan Li,PhD    
    Affiliation: Associate Professor, Vanderbilt University

    Dr. Bingshan Li is Associate Professor at Vanderbilt Genetics Institute. Dr. Li’s research is focused on developing statistical methods and computational tools to understand genetics of human complex traits. Dr. Li is a pioneer in the development of gene-based collapsing methods for analyzing rare variants (almost 10 years ago), which laid a foundation for sequencing data analysis for complex traits. As a result, he received the C.W. Cotterman Award by the American Society of Human Genetics in 2009. He is now focused on developing methods for analyzing noncoding rare variants in whole genome sequencing (WGS) data. Dr. Li is a PI of one of the three Analysis Centers for the Genome Sequencing Program, which is to carry out whole genome sequencing over >100,000 samples across multiple complex diseases. 

    Genome-wide association studies (GWAS) have identified numerous variants associated with schizophrenia (SCZ). Translating GWAS findings to biological mechanisms, especially clinical applicability, however, remains a major challenge. In this talk, I will introduce a statistical framework that integrates multiple -omics data to identify SCZ risk genes based on GWAS findings. The risk genes identified are highly consistent with the leading pathophysiological hypotheses of SCZ, specifically expressed in brain tissues, and enriched in de novo mutations in a broader range of psychiatric disorders (e.g. autism, developmental diseases and intellectual disability). Furthermore, the risk genes are enriched in drug targets, providing candidate genes for therapeutic development. We further investigated the expression patterns of risk genes across multiple tissue- and cell type-specific transcriptomic data, and used machine learning approaches to build models to predict risk genes across the genome

    February 9, 2018

    Topic: Genomic disgnosis of developmental diabilities   
    Speaker: Greg Cooper, PhD 
    Affiliation: Faculty Investigator, HudsonAlpha Institute for Biotechnology

    January 26, 2018

    Topic: Impact of rare variants on eft ventrivular traits in African American using WGS 
    Speaker: Rafet Al-Tobasei, PhD
    Affiliation: T32 Fellow, UAB Department of Biostatistics

    January 12, 2018

    Topic: Intergrative Anlaysis of Cancer Progression
    Speaker: Sooryanarayana Varambally, PhD
    Affiliation: Associate Professor, UAB Department of Pathology

Clinical Informatics Seminar Archive

  • 2023

    "Taming a Wolf in Sheep's Clothing: Informatics Infrastructure for Detecting and Monitoring Systemic Lupus Erythematosus Using Electronic Health Record Data"

    Theresa L. Walunas, Ph.D., FAMIA
    Assistant Professor of Medicine
    Division of General Internal Medicine
    Associate Director, Center for Health Information Partnerships
    Northwestern University, Feinberg School of Medicine

    "Challenges, Opportunities, and Best Practices for Clinical Decision Support (CDS) Governance and Implementation"

    Richard Schreiber, M.D.
    Associate Chief Medical Informatics Officer, Penn State Health Holy Spirit Medical Center
    Associate, Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health
    Professor of Medicine, Geisinger Commonwealth School of Medicine

  • 2022

    Friday, Dec 2 | Clinical Informatics

    "OneFlorida+ Informatics Infrastructure and Tools to Accelerate Clinical Research"

    William R. Hogan, MD, MS
    Professor, Health Outcomes and Biomedical Informatics
    Director of Biomedical Informatics, Clinical and Translational Sciene Institute, University of Florida
    Director of Informatics, OneFlorida Clinical Research Consortium

    Friday, Nov 18 | Clinical Informatics

    "Biomedical Informatics: Year in Review"

    Jim Cimino, MD, FACMI, FACP
    Distinguished Professor of Medicine
    Department of Medicine, Division of General Internal Medicine
    UAB Heersink School of Medicine
    Director, UAB Informatics Institute
    Co-director, Center for Clinical and Translational Science

    Friday, Oct 21 | Clinical Informatics

    "Toward Designing Context-Aware Electronic Health Records with a Patient-Specific Knowledge Base"

    Tiago Colicchio, Ph.D.
    Assistant Professor of Medicine
    Division of General Internal Medicine and Informatics Institute

    Thursday, Oct 13 | Clinical Informatics

    "Unbiased Representation of Clinical Data for Precise Patient Outcome Prediction"

    Jin Chen, Ph.D.
    Associate Professor, Division of Biomedical Informatics
    Department of Internal Medicine
    Department of Computer Science
    University of Kentucky

    Friday, Oct 7 | Clinical Informatics

    "Data Mapping Patient Reported Outcomes to Support Remote Patient Monitoring"

    Jeffrey R. Curtis, MD, MS, MPH
    Harbart Ball Professor of Medicine, Epidemiology & Computer Science
    Division of Clinical Immunology & Rheumatology

    Alfredo Guzman, MSHI
    Research Informatics Serivce Center (RISC) 

    Friday, Sep 16 | Clinical Informatics

    "Applications of Human Factor Engineering for Better Clinical Decision Support (CDS)"

    Swaminathan Kandaswamy, Ph.D 

    Assistant Professor of Pediatrics
    Emory University, School of Medicine

    Friday, Sept 2 | Clinical Informatics

    Translational Artificial Intelligence (AI): The Need to Translate from Basic Science to Clinical Value

    William Hersh, MD, FAMCI, FAMIA, FIAHSI, FACP
    Professor and Chair, Department of Medical Informatics and Clinical Epidemiology (DMICE)
    Oregon Health and Science University

    Friday, April 1 | Clinical Informatics

    Current Practices and Frontiers in Rule-Based Electronic Phenotyping

    Fabrício Kury, MD
    Clinical Data Strategist

    Friday, March 11 | Clinical Informatics

    Development of Computable Pediatric Chemotherapy Regimen Knowledge for Cancer Clinical Care and Research

    Wayne H. Liang, MD, MS
    Pediatric Hematologist/Oncologist and Physician Informaticist, Aflac Cancer & Blood Disorders Center
    Children’s Healthcare of Atlanta Assistant Professor of Pediatrics, Emory University School of Medicine

    Friday, March 4 | Clinical Informatics

    Public and Population Health Informatics Challenges in addressing Health Disparities

    Raymonde Uy, MD, MBA
    Physician Informaticist

    Friday, February 4 | Clinical Informatics

    Data Is Transforming the Scientific Method

    Nicholas P. Tatonetti, PhD, FACMI
    Associate Professor of Biomedical Informatics
    Vagelos College of Physicians and Surgeons
    Columbia University

    Friday, January 21 | Clinical Informatics

    Multi-omic Translational Approaches to Investigate Therapeutic Resistance in Glioblastoma

    Christopher D. Willey, MD, PhD
    Director UAB Kinome Core
    Professor of Radiation Oncology
    UAB Heersink School of Medicine

    Friday, January 14 | Clinical Informatics

    How to Teach a Computer to Learn about Microbes

    Marcin P. Joachimiak, PhD
    Computational Biologist, Environmental Genomics and Systems Biology
    Division, Biosystems Data Science Department
    Lawrence Berkeley National Laboratory

  • 2021
    Friday, November 19

    “Translating Big Data to Effective Cancer Therapy”

    Jim Cimino, MD, FACMI, FACP
    Distinguished Professor of Medicine
    Department of Medicine, Division of General Internal Medicine
    Director, UAB Informatics Institute
    Co-director, Center for Clinical & Translational Science

    Friday, October 15

    “Effective Use of EHR Data to Support Research: The Complementary Roles of Data Extraction and Data Transformation”

    James Willig, M.D., MSPH
    Associate Professor
    UAB School of Medicine,Department of Medicine, Division of Infectious Diseases
    Associate Dean of Clinical Education
    Director, Research and Informatics Services Center, Center for AIDS Research

    Matthew Wyatt, MSHI
    Director of Clinical Research Informatics
    Informatics Institute
    UAB Heersink School of Medicine

    Friday, October 1 

    “Translating Informatics Research into Practice ”"

    Daniel Fabbri, PhD, FAMIA.
    Assistant Professor of Biomedical Informatics and Computer Science
    Vanderbilt University School of Medicinee

    Friday, September 17 

    “Incorporation of AHA Annual Survey Data into the UAB SHP Health Services Research Data Warehouse”"

    Nichole Samuy, M.D.
    Associate Professor of Pediatrics
    Department of Pediatrics
    Division of Pediatric Hospital Medicine
    UAB Heersink School of Medicine

    Friday, September 3

    "An Integrated Optimization and Machine Learning Model to Predict Admission Status in Emergency Department Patients"

    Abdulaziz Ahmed, Ph.D.
    Assistant Professor of Health Services Administration
    UAB School of Health Professions
    Associate Professor of Preventive Medicine

    Friday, April 16

    “A Multidimensional Precision Medicine Approach Identifies an Autism Subtype Characterized by Dyslipidemia”
    Yuan Luo, Ph.D.
    Associate Professor of Preventive Medicine
    Chief AI Officer, Northwestern University Clinical and Translational Sciences Institute (NUCATS) and Institute of Augmented Intelligence in Medicine (IAIM)
    Northwestern University Feinberg School of Medicine

    Friday, March 5

    “Building tools to support family centered care: the InfoSage experience"
    Charles Safran, M.D., MS, FACMI
    Professor of Medicine
    Harvard Medical School

    Friday, February 5

    “Update on UAB Autopsy Synoptic Reporting and Development of a COVID-19 Autopsy Virtual Biorepository”
    Paul Benson, M.D.
    Associate Professor
    Department of Pathology
    Division of Anatomic Pathology
    UAB Heersink School of Medicine

    Friday, January 29

    "Leveraging Informatics to Create Learning Health Systems: Now, It’s Personal!"
    Peter J. Embí, M.D., MS, FACP, FACMI, FAMIA
    President & CEO
    Regenstrief Institute
    Leonard Betley Professor of Medicine and Associate Dean for Informatics & Health Services Research
    Indiana University School of Medicine
    Associate Director of Informatics
    Indiana Clinical and Translational Sciences Institute (CTSI)

    Friday, January 15

    "Public Health Informatics in the Time of COVID-19"
    Nicholas Soulakis, Ph.D.
    Assistant Professor of Preventive Medicine (Health and Biomedical Informatics, Epidemiology) and Medical Social Sciences
    Northwestern University Feinberg School of Medicine
    Chief Public Health Informatics Advisor
    Chicago Department of Public Health
    Illinois Department of Public Health

  • 2020
    December 18, 2020

    "Facilitating collaborative research: data harmonization and pooling"
    Eneida A. Mendonca, M.D., Ph.D., FAAP, FACMI
    Vice President for Research Development
    Interim Director
    Center for Biomedical Informatics
    Regenstrief Institute
    Professor of Pediatrics and Biostatistics
    Indiana University School of Medicine

    December 04, 2020

    “A Critical Analysis of COVID-19 Research Literature: Text Mining Approach”
    Ferhat Zengul, Ph.D.
    Assistant Professor
    Health Services Administration
    School of Health Professions 

    Nurettin Oner, Ph.D., MHA
    Research Associate
    Health Services Administration
    School of Health Professions

    Bunyamin Ozaydin, Ph.D.
    Assistant Professor
    Health Services Administration
    School of Health Professions

    November 20, 2020

    “Biomedical Informatics Year in Review”
    James Cimino, M.D., FACMI, FACP
    Department of Medicine
    Division of General Internal Medicine
    Informatics Institute
    UAB Heersink School of Medicine

    November 6, 2020

    “Are We Talking About the Same Patient? Studying Nurse-Physician Language Differences”
    Andrew Boyd, M.D.
    Associate Professor
    Biomedical and Health Information Sciences
    University of Illinois at Chicago

    October 2, 2020

    "The Peril and Promise of Clinical Informatics"
    David M. Liebovitz, M.D.
    Co-Director, Institute for Augmented Intelligence in Medicine - Center for Medical Education in Data Science and Digital Health
    Associate Vice Chair for Clinical Informatics, Department of Medicine
    Associate Professor of Medicine (General Internal Medicine and Geriatrics)
    Northwestern University Feinberg School of Medicine

    April 17, 2020

    Topic: “The Role of Telehealth in Reducing Health Disparities”
    Speaker: Mohanraj Thirumalai, Ph.D., MEng, MS
    Affiliation: Assistant Professor, Health Services Administration, UAB School of Health Professions

    February 21, 2020

    Topic: "Diagnostic Decision Support Systems: An Educational Intervention to Increase Use"
    Speaker: Eta Berner, Ed.D.
    Affiliation: Professor, UAB School of Health Professions, Director of the UAB Center for Health Informatics for Patient Safety/Quality

    January 31, 2020

    Topic: "Re-Envisioning Informatics in Nursing Education for 2020 and Beyond"
    Speaker: Marisa L. Wilson, DNSc, MHSc, RN, CPHIMS, RN-BC, FAAN
    Affiliation: Associate Profesor of Nursing, Director, Nursing Academic Affairs, Coordinator, Informatics Specialty Track, Director, Health Systems Leadership Pathway, UAB School of Nursing

    January 17, 2020

    Topic: "The ‘F Word’ in FAIR – Finding Objects in the Scientific Record to Enable Research Synthesis and Inform Clinical Practice"
    Speaker: Kathryn Kaiser, Ph.D.
    Affiliation: Assistant Professor, Department of Health Behavior, UAB School of Public Health, Senior Scientist, Center for Outcomes and Effectiveness Research and Education (COERE), Scientist, Nutrition Obesity Research Center (NORC)

  • 2019

    December 6, 2019

    Topic: "Biomedical Informatics Year in Review"
    Speaker: James Cimino, M.D.
    Affiliation: Professor, Department of Medicine, Director, Informatics Institute, UAB Heersink School of Medicine

    November 1, 2019

    Topic: "A Design Science Approach to Community-Based Participatory Research: An Information System for Certified Peer Specialists in Opioid Use Disorder"
    Speaker: Sue Feldman, RN, MEd, Ph.D.
    Affiliation: Associate Professor and Director, Graduate Programs in Health Informatics, Health Services Administration, UAB School of Health Professions

    October 18, 2019

    Topic: "Using Industrial Engineering and Lean Techniques to Mitigate Burnout in Care Teams"
    Speaker: Daniel Silva, Ph.D.
    Affiliation: Assistant Professor, Department of Industrial and Systems Engineering, College of Engineering, Auburn University

    October 4, 2019

    Topic: "Transforming Cancer Clinical Research & Care Delivery through Clinical Informatics"
    Speaker: Wayne Liang, M.D.
    Affiliation: Assistant Professor, UAB Heersink School of Medicine, Department of Pediatrics, Division of Hematology/Oncology, Informatics Institute 

    September 6, 2019

    Topic: "Transitioning from one EHR to Another: Opportunities and Challenges"
    Speaker: Amy Y. Wang, M.D., MBI
    Affiliation: Associate Professor, UAB Heersink School of Medicine, Department of Medicine, Informatics Institute 

    April 5, 2019

    Topic: “Concepts, Relations, and Properties of a Clinical Ontology”
    Speaker: Irushi Dissanayake
    Affiliation: Postdoctoral Researcher, UAB Informatics Institute

    March 15, 2019

    Topic: "Toward Designing Smarter Electronic Clinical Documentation Systems"
    Speaker: Tiago Colicchio, Ph.D.
    Affiliation: Assistant Professor, Department of Medicine, Informatics Institute, UAB

    March 1, 2019

    Topic: “Gamification, patient reported outcomes and patient based metrics”
    Speaker: James, Willig, M.D., MSPH
    Affiliation: Associate Professor, Division of Infectious Diseases, UAB Department of Medicine

    February 15, 2019

    Topic: "Population Genomics and Gene Expression Data Analysis"
    Speaker: Linyong Mao, Ph.D.
    Affiliation: Assistant Professor, Department of Biochemistry and Molecular Biology, Howard University

    February 1, 2019

    Topic: “Clinical Bioinformatics Methods to Study Genomic Mutational Profiles in Cancer Disease”
    Speaker: Yvonne Edwards, Ph.D.
    Affiliation: Director of Bioinformatics, Program in Molecular Medicine and Research, Assistant Professor, University of Massachusetts Medical School

    January 18, 2019

    Topic: "Actually See Your Patient, Not Just Inside Them: A New Technology and Paradigm for Medical Imaging Care"
    Speaker: Srini Tridandapani, M.D., Ph.D., MBA
    Affiliation: Vice Chair, Imaging Informatics, Professor, Department of Radiology- Cardiopulmonary Section 

    January 4, 2019

    Topic: “Incorporating CMS Medicare Cost Report data into Health Services Research Data Infrastructure”
    Speaker: Bunyamin Ozaydin, Ph.D.
    Affiliation:  Assistant Professor, UAB School of Health Professions

  • 2018

    December 7, 2018

    Topic: "Quality Improvement with CDW Mining, Graph-Network Analysis & Visualization: The INFECTALYTICS Project"
    Speaker:  Allen Bryan, M.D., Ph.D.
    Affiliation:  Assistant Professor, Department of Pathology, Division of Laboratory Medicine

    November 30, 2018

    Topic: "Investigating the Use of Patient Attributes to Predict False-Positive Medical Alerts" 
    Speaker: Tim Kennell
    Affiliation: M.D./Ph.D. Student, UAB, GBS

    November 9, 2018

    Topic: "Biomedical Informatics Year in Review"
    Speaker: James J. Cimino, M.D.
    Affiliation: Director, UAB Informatics Institute, Professor of Medicine

    November 2, 2018

    Topic: "Informatics in Precision Medicine: When Data Is the Drug"
    Speaker: Matthew Might, Ph.D.
    Affiliation: Director, UAB Hugh Kaul Precision Medicine Institute, Professor of Medicine

    October 19, 2018

    Topic: “Beyond Patient Portals: Informatics Support for Patient Engagement in the Inpatient Setting”
    Speaker: Wayne Liang, M.D.
    Affiliation: Assistant Professor, UAB Department of Pediatrics, Division of Pediatric Hematology/Oncology 

    October 5, 2018

    Topic: "Physician Performance and Preference for Clinical Data in Structured and Unstructured Formats."
    Speaker: Eta Berner, Ed.D.
    Affiliation: Professor, Director, Center for Health Informatics for Patient Safety/Quality UAB School of Health Professions

    September 5, 2018

    Topic:“Putting the “Why” in “EHR”: Toward the Development of an Ontology for  Representing Clinical Reasoning in Clinical Notes”
    Speaker:  Jim Cimino, M.D., FACMI, FACP
    Affiliation: Professor, Director-Informatics Institute, Co-Director-Center for Clinical and Translational Science